MONDAY, June 27 (HealthDay News) -- The life expectancy of patients with childhood-onset, type 1 diabetes (T1D) has increased over time, according to a study presented at the American Diabetes Association's 71st Scientific Sessions, held from June 24 to 28 in San Diego.
Rachel G. Miller, from the University of Pittsburgh, and colleagues estimated the all-cause mortality and life expectancy of patients with childhood-onset T1D enrolled in the Pittsburg Epidemiology of Diabetes Complications study cohort. Improvements in life expectancy were compared between 390 participants from the 1950 to 1964 diagnosis cohort and 543 from the 1965 to 1980 diagnosis cohort.
The investigators identified a significant decline in mortality in individuals from the 1965 to 1980 diagnosis cohort compared to those from the 1950 to 1964 diagnosis cohort, with 30-year mortality of 11.6 and 35.6 percent, respectively. The 1965 to 1980 cohort had an estimated life expectancy at birth of 68.8 years, which was approximately 15 years more than that of the 1950 to 1964 cohort (53.4 years); over the same time period, the increase in the life expectancy of the general U.S. population was less than one year. The estimated life expectancy of the 1965 to 1980 cohort was around four years less than that for a similar cohort of the U.S. general population (72.4 years), whereas the 1950 to 1965 cohort had a life expectancy around 18 years less than the comparable U.S. general population (71.5 years). The estimated 15-year improvement in life expectancy between the two cohorts was independent of the gender or pubertal status at diagnosis.
"The gap in survival between T1D and the U.S. general population appears to be rapidly diminishing," the authors write.
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