Despite Progress, Mortality Still Risk Up in Patients With T2DM
Risks vary per age, glycemic control, and renal complications
THURSDAY, Oct. 29, 2015 (HealthDay News) -- Type 2 diabetes still substantially increases mortality risk, with the degree of risk varying with age, renal complications, and glycemic control, according to research published in the Oct. 29 issue of the New England Journal of Medicine.
The new study used data from the Swedish National Diabetes Register to compare the mortality rate among 435,369 people with type 2 diabetes with that of a healthy control group of 2.1 million people. The researchers found that excess risk of death was two to three times higher among those younger than 55, compared to between 30 and 40 percent higher for patients aged 65 to 75.
Patients younger than 55 who've entered end-stage renal disease are 14 times more likely to die than a healthy person. End-stage renal disease also multiplies the mortality risk seven-fold for those 55 to 64, and six-fold for those 65 to 74, the investigators found.
Anyone who didn't manage their diabetes through lifestyle changes, insulin, or medication faced a greatly increased risk of death, said study coauthor Mikhail Kosiborod, M.D. Kosiborod is a cardiologist at Saint Luke's Mid America Heart Institute and a professor of medicine at the University of Missouri-Kansas City. "If you look at the data, regardless of the age we look at, regardless of everything else, the worse the glycemic control the higher the mortality," he told HealthDay.