HealthDay operates under the strictest editorial standards. Our syndicated news content is completely independent of any financial interests, is based solely on industry-respected sources and the latest scientific research, and is carefully fact-checked by a team of industry experts to ensure accuracy.
- All articles are edited and checked for factual accuracy by our Editorial Team prior to being published.
- Unless otherwise noted, all articles focusing on new research are based on studies published in peer-reviewed journals or issued from independent and respected medical associations, academic groups and governmental organizations.
- Each article includes a link or reference to the original source.
- Any known potential conflicts of interest associated with a study or source are made clear to the reader.
Please see our Editorial and Fact-Checking Policy for more detail.Editorial and Fact-Checking Policy
HealthDay Editorial Commitment
HeathDay is committed to maintaining the highest possible levels of impartial editorial standards in the content that we present on our website. All of our articles are chosen independent of any financial interests. Editors and writers make all efforts to clarify any financial ties behind the studies on which we report.
TUESDAY, Sept. 29, 2015 (HealthDay News) -- Blood tests may identify women with lupus who are at high risk for complications during pregnancy, according to a new study.
Lupus is an immune system disorder known to increase the chances of pregnancy problems such as preeclampsia and miscarriage.
This new research found that monitoring for certain "biomarkers" -- or indicators -- in the blood of lupus patients during early pregnancy can identify those who are likely to have normal pregnancies and those who are at risk for problems, the study's authors said.
The researchers analyzed data from 497 pregnant women with lupus and 207 pregnant women without the disease. They were checked every month of pregnancy.
The study found that biomarkers called circulating angiogenic factors -- which regulate development of the placenta and influence the health of blood vessels in the mother -- can be assessed early in pregnancy.
As early as 12 to 15 weeks into pregnancies, changes in these biomarkers can signal risk for complications such as the blood pressure problem preeclampsia, fetal growth problems, preterm birth and death of the fetus or newborn, the study authors said.
Analyzing these biomarkers could also rule out increased risk of severe complications in most patients, resulting in less anxiety and more appropriate care, according to the authors of the study published Sept. 29 in the American Journal of Obstetrics & Gynecology.
"Given that over 20 percent of pregnant women with [lupus] experience adverse pregnancy outcomes, the ability to identify patients early in pregnancy, who are destined for poor outcomes, would significantly impact care of this high risk population," lead investigator Dr. Jane Salmon, of the Hospital for Special Surgery and Weill Cornell Medical College in New York City, said in a journal news release.
The study shows that when levels of the biomarkers are normal, 95 percent of women with lupus will have no pregnancy complications, according to Dr. Roberto Romero, the journal's editor-in-chief for obstetrics.
"Therefore, the simple measurement of these biomarkers can be highly reassuring to mothers, families and physicians," Romero, chief of the Perinatology Research Branch at the U.S. National Institute of Child Health and Human Development, said in the news release.
The Lupus Foundation of America has more about lupus and pregnancy.
This story may be outdated. We suggest some alternatives.
The content contained in this article is over two years old. As such our recommendation is that you reference the articles below for the latest updates on this topic. This article has been left on our site as a matter of historic record. Please contact us at firstname.lastname@example.org with any questions.
Updated on May 31, 2022