Here are what the editors at HealthDay consider to be the most important developments in Family Practice for April 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Screening Benefits Women in 40s With High Breast CA Risk
MONDAY, April 30 (HealthDay News) -- Women in their 40s, with at least a two-fold increased risk of breast cancer, benefit from biennial screening mammography; and having extremely dense breasts or first-degree relatives with breast cancer is associated with a two-fold increased risk of breast cancer for women in their 40s, according to two studies published in the May 1 issue of the Annals of Internal Medicine.
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Prenatal Insecticide Exposure Alters Developing Brain
MONDAY, April 30 (HealthDay News) -- Prenatal exposure to chlorpyrifos (CPF), an organophosphate insecticide, correlates with structural changes in the developing brain, according to a study published online April 30 in the Proceedings of the National Academy of Sciences.
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Imaging Provides Clues to Distribution of Fat in Children
MONDAY, April 30 (HealthDay News) -- The use of imaging studies has contributed to an understanding of differences in fat distribution and their link to metabolic disease in childhood, according to research published online April 22 in Obesity Reviews.
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Electronic Reminders Up Meds Adherence in Short Term
MONDAY, April 30 (HealthDay News) -- The use of electronic reminders (short message service [SMS] reminders, electronic reminder devices, or pagers) is associated with improved adherence to chronic medications in the short term, according to a review published online April 25 in the Journal of the American Medical Informatics Association.
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Levaquin Approved to Treat or Prevent Plague
MONDAY, April 30 (HealthDay News) -- Approval of the antibiotic Levaquin (levofloxacin) has been expanded by the U.S. Food and Drug Administration to include plague, a rare but deadly bacterial infection.
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Stress Reduction Ups Health Status in Type 2 Diabetes
FRIDAY, April 27 (HealthDay News) -- A mindfulness-based stress reduction (MBSR) intervention is effective at improving health status and lowering levels of depression among patients with type 2 diabetes, according to a study published in the May issue of Diabetes Care.
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Sleep Measures Do Not Predict Clinical Pain in Fibromyalgia
FRIDAY, April 27 (HealthDay News) -- For patients with fibromyalgia, spatial extent of pain, pain aftersensation, and negative mood account for approximately one-third of the variance in clinical pain, but sleep measures do not significantly predict pain, according to a study published in the April issue of The Journal of Pain.
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About Half of Teens Who Self-Harm Were Frequently Bullied
FRIDAY, April 27 (HealthDay News) -- About half of young adolescents who have self-harmed were frequently bullied, and self-harm among the bullied is more likely in those with mental health problems, a family history of suicide, or a history of being physically abused by an adult, according to a study published online April 26 in BMJ.
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Cancer Worry Linked to Continued Symptom Burden
FRIDAY, April 27 (HealthDay News) -- Age, fatigue, symptom burden, and risk perception are significantly associated with greater cancer worry three years after completing adjuvant treatment for breast cancer, according to a study published online March 15 in Psycho-Oncology.
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Persistent Constipation Rates May Be Lower Than Reported
FRIDAY, April 27 (HealthDay News) -- The clinical symptoms of persistent and nonpersistent chronic constipation (CC) are similar, with persistent CC estimated to have a prevalence of 3 percent, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.
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Sunscreen Use May Lead to Vitamin D Deficiency
FRIDAY, April 27 (HealthDay News) -- Using the amount and sun protection factor (SPF) of sunscreen recommended by the World Health Organization (WHO) is associated with little or no vitamin D production, suggesting that regular sunscreen use may lead to vitamin D deficiency, according to research published online April 18 in the British Journal of Dermatology.
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Antiretroviral Prophylaxis May Cut Breastfeeding HIV Spread
THURSDAY, April 26 (HealthDay News) -- Breastfeeding HIV-infected mothers are less likely to transmit the virus to their infants when either receive antiretroviral drugs, although weaning at six months may be detrimental, according to updated trial results published online April 26 in The Lancet.
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Sleep of Short Duration Common in U.S. Workers
THURSDAY, April 26 (HealthDay News) -- A substantial proportion of workers in the United States get less sleep than recommended by the National Sleep Foundation, according to a report published in the April 27 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
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Berries May Slow Cognitive Decline in Older Women
THURSDAY, April 26 (HealthDay News) -- Flavonoid-rich blueberries and strawberries may reduce cognitive decline in elderly women, according to a study published online April 25 in the Annals of Neurology.
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Heart Surgery Safe for Compensated Cirrhosis Patients
THURSDAY, April 26 (HealthDay News) -- Patients with compensated cirrhosis, defined by a Child-Pugh (CP) score of <8, have no significant increase in postoperative mortality and morbidity following cardiac surgery with cardiopulmonary bypass, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.
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Nutrition, Exercise Guidelines Updated for Cancer Survivors
THURSDAY, April 26 (HealthDay News) -- The American Cancer Society has updated the 2006 guidelines to provide new evidence and clinical practices related to nutrition and physical activity for cancer survivors during the continuum of cancer care, according to a report published online April 26 in CA: A Cancer Journal for Clinicians.
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Hyperalgesia Similar With Drug Therapies for Heroin Addiction
THURSDAY, April 26 (HealthDay News) -- Heroin-addicted patients treated with methadone or buprenorphine have a heightened sensitivity to pain, and the hyperalgesia does not change over the course of treatment, according to a study published in the April issue of The Journal of Pain.
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Subtype Best Predictor of Basal Cell Carcinoma Invasion Depth
THURSDAY, April 26 (HealthDay News) -- Basal cell carcinoma (BCC) subtype identified on biopsy and excision specimens is the best predictor of depth of invasion, according to a study published online April 16 in the Journal of the American Academy of Dermatology.
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Age, Life Expectancy Influence Termination of PSA Screening
THURSDAY, April 26 (HealthDay News) -- Most primary care providers consider both a man's age and life expectancy in deciding whether to discontinue prostate-specific antigen (PSA) screenings, but multiple factors are involved in this decision, according to a study published online April 19 in Cancer.
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Early Menopause Ups Risk of Osteoporosis, Fractures, Death
THURSDAY, April 26 (HealthDay News) -- The occurrence of menopause before age 47 correlates with increased osteoporosis at age 77, increased incidence of fragility fractures, and increased mortality, according to a study published online April 25 in BJOG: An International Journal of Obstetrics and Gynaecology.
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Accelerated Aging Evident in Cocaine-Dependent Individuals
THURSDAY, April 26 (HealthDay News) -- The brains of individuals addicted to cocaine show accelerated loss of gray matter over and above the loss due to normal aging, according to a letter published online April 24 in Molecular Psychiatry.
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Erosive, but Not Nonerosive, GERD Ups Esophageal CA Risk
WEDNESDAY, April 25 (HealthDay News) -- Patients with gastroesophageal reflux disease with a history of esophagitis are at increased risk for esophageal adenocarcinoma, although the absolute risk is low, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.
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Warfarin Keeps Stroke Risk Low in Patients With A-Fib
WEDNESDAY, April 25 (HealthDay News) -- Use of warfarin for stroke prevention in patients with nonvalvular atrial fibrillation (AF) is associated with a low risk of stroke or systemic embolism, according to a meta-analysis published in the April 23 issue of the Archives of Internal Medicine.
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Primary Enforcement Leads to Higher Teen Seat Belt Use
WEDNESDAY, April 25 (HealthDay News) -- Teen drivers and passengers in states with secondary safety belt enforcement laws are less likely to wear seat belts compared with teens in states with primary enforcement, according to a study published in the American Journal of Public Health.
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Low-Dose CT Noninferior for Diagnosing Appendicitis
WEDNESDAY, April 25 (HealthDay News) -- For young adults with suspected appendicitis, low-dose computed tomography (CT) is noninferior to standard-dose CT with respect to negative appendectomy rates, according to a study published in the April 26 issue of the New England Journal of Medicine.
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Amyloid-β-Linked Cognitive Decline Linked to Phospho-Tau
WEDNESDAY, April 25 (HealthDay News) -- In cognitively normal older individuals, amyloid-β (Aβ)-associated longitudinal cognitive decline only occurs in the presence of elevated phospho-tau 181 (p-tau181p) in the cerebrospinal fluid (CSF), according to a study published online April 23 in the Archives of Neurology.
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Ultrasound May Safely Rule Out DVT in Pregnancy
WEDNESDAY, April 25 (HealthDay News) -- For pregnant and postpartum women, a single complete compression ultrasonography may safely exclude a diagnosis of deep vein thrombosis, according to a study published online April 24 in BMJ.
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Inducing for Premature Rupture of Membranes Not Better
WEDNESDAY, April 25 (HealthDay News) -- In pregnant women with preterm prelabor rupture of membranes (PPROM), inducing labor and watchful waiting are similarly effective in terms of pregnancy outcomes such as neonatal sepsis and cesarean section, according to a study published online April 24 in PLoS Medicine.
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Exposure to Violence Wears on Children's DNA
WEDNESDAY, April 25 (HealthDay News) -- Children who are exposed to violence have significantly more telomere erosion than their unexposed peers, according to a study published online April 24 in Molecular Psychiatry.
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Anatomic Existence of the G-Spot Reported
WEDNESDAY, April 25 (HealthDay News) -- The anatomic existence of the G-spot has been documented, and it has been identified as a distinguishable anatomic structure located on the dorsal perineal membrane, according to a study published in the May issue of The Journal of Sexual Medicine.
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Botox Modestly Improves Chronic Headaches, Migraines
WEDNESDAY, April 25 (HealthDay News) -- Botulinum toxin A provides a modest benefit for patients with chronic migraine headaches and chronic daily headaches, compared with placebo, according to a meta-analysis published in the April 25 issue of the Journal of the American Medical Association.
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Nursing Excellence Ups Very Low Birth Weight Baby Outcomes
WEDNESDAY, April 25 (HealthDay News) -- For very low birth weight (VLBW) infants, hospitals with recognition for nursing excellence (RNE) have significantly lower rates for hospital infection, seven-day mortality, and severe intraventricular hemorrhage, but not 28-day mortality or hospital stay mortality, according to a study published in the April 25 issue of the Journal of the American Medical Association.
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Resistance Training Aids Memory in Senior Women
WEDNESDAY, April 25 (HealthDay News) -- For senior women with mild cognitive impairment, twice-weekly resistance training (RT) for six months is associated with improved cognition and brain plasticity compared with balance and tone (BAT) exercises, according to a research letter published in the April 23 issue of the Archives of Internal Medicine.
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Mortality High for Cardiac Device Infective Endocarditis
TUESDAY, April 24 (HealthDay News) -- Patients with infective endocarditis involving implanted cardiac devices experience high in-hospital and one-year mortality rates, particularly if there is valve involvement, according to a study published in the April 25 issue of the Journal of the American Medical Association.
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USPSTF Guidelines Haven't Changed PSA Screening Practice
TUESDAY, April 24 (HealthDay News) -- Despite the 2008 changes in U.S. Preventive Services Task Force (USPSTF) recommendations against prostate-specific antigen (PSA)-based screening for prostate cancer in men 75 years or older, screening rates remained unchanged for men of all ages between 2005 and 2010, according to a research letter published in the April 25 issue of the Journal of the American Medical Association.
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Text Messages to Parents Promote Flu Shots for Children
TUESDAY, April 24 (HealthDay News) -- A text messaging-based intervention increases influenza vaccination compared with usual care in a low-income, urban population, although overall rates of vaccination remain low, according to a study published in the April 25 issue of the Journal of the American Medical Association.
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Subclinical Hyperthyroidism Tied to Coronary Heart Disease
TUESDAY, April 24 (HealthDay News) -- Subclinical hyperthyroidism is associated with increased risk of coronary heart disease (CHD) morbidity and mortality; and treatment with levothyroxine for subclinical hypothyroidism is associated with fewer ischemic heart disease (IHD) events in patients aged 40 to 70 years, according to two studies published online April 23 in the Archives of Internal Medicine.
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Patients With Acute Low Back Pain Have Poor Prognosis
TUESDAY, April 24 (HealthDay News) -- Few patients with acute low back pain (LBP), with or without sciatica, declare sick leave; however, approximately half have one or more recurrences and a considerable proportion experience chronic pain six months or longer after the initial episode, according to a study published in the April 15 issue of Spine.
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2001 to 2010 Saw 74 Percent Drop in Global Measles Mortality
TUESDAY, April 24 (HealthDay News) -- From 2001 to 2010, there was a 74 percent decrease in estimated global measles mortality, with mortality in India and the World Health Organization (WHO) African region accounting for most of the estimated cases in 2010, according to a study published online April 24 in The Lancet.
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Meds, Clinic Noncompliance Linked to Mortality in Diabetes
TUESDAY, April 24 (HealthDay News) -- Insulin-treated patients with type 2 diabetes who are noncompliant with their medication or clinic appointments face increased all-cause mortality, according to a study published online April 17 in Diabetes Care.
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S. Aureus, Enterotoxins ID'd in Atopic Keratoconjunctivitis
MONDAY, April 23 (HealthDay News) -- Staphylococcus aureus (S. aureus) and S. aureus-secreted enterotoxins (SE) are frequently found in patients with atopic keratoconjunctivitis (AKC), particularly in those with corneal ulceration, according to a study published online April 10 in Allergy.
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Bladder Cancer Diagnosis Encourages Smokers to Quit
MONDAY, April 23 (HealthDay News) -- Smokers with a new diagnosis of bladder cancer are significantly more likely to quit compared with smokers in the general population, according to a study published online April 23 in the Journal of Clinical Oncology.
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Angiotensin Receptor Blockers Reduce No-Reflow Post-PCI
MONDAY, April 23 (HealthDay News) -- For patients with acute myocardial infarction (AMI), pretreatment with angiotensin receptor blockers (ARBs) is linked with reduced incidence of the no-reflow phenomenon after percutaneous coronary intervention (PCI), according to a study published online April 10 in Cardiovascular Therapeutics.
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Shingles Vaccine Generally Well Tolerated in Older Adults
MONDAY, April 23 (HealthDay News) -- The zoster vaccine is safe and well tolerated in older adults, despite an increased risk of allergic reaction in the days following vaccination, according to a study published in the Journal of Internal Medicine.
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Metabolites Linked to Insulin Resistance in Normoglycemia
MONDAY, April 23 (HealthDay News) -- Twenty metabolites, including amino acids, intermediates in glucose synthesis, ketone bodies, and fatty acids, are associated with insulin resistance, according to a study published online April 17 in Diabetes.
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Massachusetts Saw Recent Drop in Pediatric Obesity
MONDAY, April 23 (HealthDay News) -- The prevalence of obesity among children younger than 6 years in a Massachusetts cohort was stable from 1999 to 2003, and decreased from 2004 to 2008, according to a study published online April 23 in Pediatrics.
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Reliability, Validity of Clinical Dehydration Scale Questioned
MONDAY, April 23 (HealthDay News) -- A previously derived clinical dehydration scale (CDS) is characterized by moderate interobserver reliability and weak links with objective measures of disease severity for children administered intravenous rehydration, according to a study published online April 23 in Pediatrics.
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High BMI Tied to Non-Specific Foot Pain, Plantar Heel Pain
MONDAY, April 23 (HealthDay News) -- Increased body mass index (BMI) correlates with non-specific foot pain in the general population, and with chronic plantar heel pain in a non-athletic population, according to a meta-analysis published online April 13 in Obesity Reviews.
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Insulin Resistance Cut-Off Established From Clamp Data
MONDAY, April 23 (HealthDay News) -- Cut-offs for predicting insulin resistance based on hyperinsulinemic-euglycemic clamp data and routinely measured clinical and biochemical variables have been determined, according to a study published online April 17 in Diabetes Care.
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Pain Coping Ability Impacts Lupus Symptomology
MONDAY, April 23 (HealthDay News) -- Pain coping strategies can significantly impact the physical symptoms and psychological distress experienced by patients with systemic lupus erythematosus (SLE), according to a study published online April 13 in Arthritis Care & Research.
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Pediatric Regimen Beats Adult Chemo for Young Adults With ALL
MONDAY, April 23 (HealthDay News) -- Adolescent and young adult patients with acute lymphoblastic leukemia (ALL) who are treated with pediatric-inspired regimens exhibit lower all-cause mortality, higher complete remission and event-free survival rates, and lower relapse rates compared with those treated with conventional adult-chemotherapy regimens, according to a study published in the May issue of the American Journal of Hematology.
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Patient-Centered Approach Key for T2DM Management
FRIDAY, April 20 (HealthDay News) -- Treatment of type 2 diabetes should be personalized in a patient-centered approach, with diet, exercise, and education forming the basis of any treatment program, supplemented by medications as necessary, according to a joint position statement issued by the American Diabetes Association and the European Association for the Study of Diabetes, published online April 19 in Diabetes Care.
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Marijuana and Tobacco Co-Use Common in Young Adults
FRIDAY, April 20 (HealthDay News) -- Half of young adult tobacco smokers also have used marijuana in the last 30 days, and co-use occurs on nearly half of the days either substance is used, according to a study published online April 19 in Addiction Science & Clinical Practice.
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Computerized Therapy Equal to Usual Care for Depressed Teens
FRIDAY, April 20 (HealthDay News) -- For adolescents presenting with depressive symptoms, use of a computerized cognitive behavior therapy intervention (SPARX; Smart, Positive, Active, Realistic, X-factor thoughts) is a potential alternative to usual care, according to a study published online April 19 in BMJ.
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Metformin + Insulin Comparable to Insulin Alone in T2DM
FRIDAY, April 20 (HealthDay News) -- For patients with type 2 diabetes, treatment with metformin and insulin has no significant effect on all-cause or cardiovascular mortality, compared with insulin alone, although data are limited and suffer from bias, according to a meta-analysis published online April 19 in BMJ.
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Impaired Fasting Glucose Affects Male Sexual Health
FRIDAY, April 20 (HealthDay News) -- Nearly 20 percent of men with sexual dysfunction have impaired fasting glucose (IFG) and are more likely than men with normal glucose levels to have severe erectile dysfunction (ED), reduced penile blood flow, and overt hypogonadism as well as increased overall cardiovascular (CV) risk, according to a study published online April 10 in The Journal of Sexual Medicine.
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QRS Width on ECG Linked to Sudden Cardiac Arrest in CAD
FRIDAY, April 20 (HealthDay News) -- For patients with coronary artery disease (CAD), QRS width on electrocardiogram and echocardiographic evidence of heart failure are associated with out-of-hospital sudden cardiac arrest (SCA), regardless of whether they have a history of previous myocardial infarction (MI), according to a study published in the May 1 issue of The American Journal of Cardiology.
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Study Compares Effectiveness of Psoriasis Treatments
FRIDAY, April 20 (HealthDay News) -- The effectiveness of therapies for psoriasis is variable, and may be lower in real-world settings than in trial settings, according to a study published in the April issue of the Archives of Dermatology.
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Race, Location Affect Probability of Survival to Age 70
FRIDAY, April 20 (HealthDay News) -- The probability of a person surviving from birth to age 70 varies according to geographic location and gender, with a set of 22 socioeconomic and environmental factors accounting for almost all the variation, according to a study published online April 17 in PLoS One.
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Letting Go of Regret Linked to Healthy Aging
FRIDAY, April 20 (HealthDay News) -- Emotionally healthy aging is associated with an ability to let go of regrets and not dwell on missed opportunities, according to a study published online April 19 in Science.
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Prisoners at Risk for Non-Communicable Diseases
FRIDAY, April 20 (HealthDay News) -- The prevalence of obesity, inadequate exercise, and poor diet among prisoners may put them at risk for non-communicable diseases (NCDS), according to a review published online April 20 in The Lancet.
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Eating Low-Fat Dairy Linked to Reduced Stroke Risk
THURSDAY, April 19 (HealthDay News) -- Eating low-fat dairy products is associated with a reduced risk of total stroke and cerebral infarctions, according to a study published online April 19 in Stroke.
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Pulmonary HTN Predicts Heart Failure After Acute MI
THURSDAY, April 19 (HealthDay News) -- Pulmonary hypertension (PH) is a strong independent predictor of heart failure in patients with acute myocardial infarction (AMI), according to a study published in the May 1 issue of The American Journal of Cardiology.
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CDC: HPV-Associated Cancers Strike More Than 30,000 Yearly
THURSDAY, April 19 (HealthDay News) -- Cancers associated with the human papillomavirus (HPV) are diagnosed in nearly 11 out of 100,000 men and women in the United States annually, and HPV vaccines play an important role in reducing the incidence of those cancers for which screening is not approved, according to a report published in the April 20 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
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Speed, Ecstasy Use in Teens Predicts Future Depression
THURSDAY, April 19 (HealthDay News) -- Use of meth/amphetamine and ±3,4-methylenedioxymethamphetamine (MDMA) among adolescents is associated with an increased risk of subsequent depressive symptoms, according to study published online April 19 in the Journal of Epidemiology & Community Health.
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Use of PICU Beds for Non-Critical Care Found to Be Significant
THURSDAY, April 19 (HealthDay News) -- Pediatric intensive care unit (PICU) beds are used for critical care services the majority of the time, but even when new patients are waiting for floor beds, at least one PICU bed is usually in use for non-critical care services, according to a study published in the April issue of the Journal of Hospital Medicine.
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Review Shows Gum Disease Does Not Cause Heart Disease
THURSDAY, April 19 (HealthDay News) -- Periodontal disease (PD) and atherosclerotic vascular disease (ASVD) share common risk factors, but there is no evidence for a causal relationship between the two, nor evidence that treating PD prevents or alters the outcomes of ASVD, according to a scientific statement from the American Heart Association (AHA) published online April 18 in Circulation.
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Room for Improvement in Knowledge of ABC Levels, Goals
THURSDAY, April 19 (HealthDay News) -- Many individuals with diabetes do not know their last hemoglobin A1C (A1C), blood pressure, and low-density lipoprotein (LDL) cholesterol levels (ABC levels), although the correlation between such knowledge and meeting targets for ABC control is unclear, according to a study published online April 12 in Diabetes Care.
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Bariatric Surgery Effective Therapy for Diabetes in Obese
THURSDAY, April 19 (HealthDay News) -- For morbidly obese patients with type 2 diabetes, bariatric surgery is more efficacious than conventional medical treatment, leading to improvement or remission of diabetes and associated comorbidities, according to a study published online April 16 in the Archives of Surgery.
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Magnetically-Controlled Rod Shows Promise for Scoliosis
THURSDAY, April 19 (HealthDay News) -- Use of a magnetically-controlled growing rod (MCGR) procedure may be effective and safe for non-invasive outpatient distraction in children with scoliosis, according to research published online April 19 in The Lancet.
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Hospital Readmission Within 30 Days More Likely in Men
THURSDAY, April 19 (HealthDay News) -- Male gender is associated with increased hospital utilization within 30 days after index discharge, with hospital utilization in the preceding six months a risk factor for both males and females, according to a study published online April 3 in BMJ Open.
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Blood Test IDs Depressive Disorder in Adolescents
THURSDAY, April 19 (HealthDay News) -- A blood test which measures transcriptomic markers may be useful for distinguishing early-onset major depressive disorder (MDD) in adolescents, according to a study published online April 17 in Translational Psychiatry.
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FDA: Clinicians Urged to Stop Using Certain Ultrasound Gel
WEDNESDAY, April 18 (HealthDay News) -- Hospitals, clinics, and health care professionals should immediately discontinue using Other-Sonic Generic Ultrasound Transmission Gel due to risk of bacterial contamination in certain batches, according to a safety communication issued April 18 by the U.S. Food & Drug Administration.
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Albendazole Cuts Enteric Parasite Prevalence in Refugees
WEDNESDAY, April 18 (HealthDay News) -- The administration of a single 600-mg dose of albendazole to United States-bound refugees prior to departure from Africa and Southeast Asia reduces the prevalence of intestinal nematodes, according to a study published in the April 19 issue of the New England Journal of Medicine.
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CV Autonomic Neuropathy Risk for CVD Despite Albumin Status
WEDNESDAY, April 18 (HealthDay News) -- Cardiovascular autonomic neuropathy (CAN) appears to affect the risk of cardiovascular disease even in type 1 diabetes patients with normal albumin excretion rates, according to a study published online April 12 in Diabetes.
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Higher Daily Physical Activity Reduces Alzheimer's Risk
WEDNESDAY, April 18 (HealthDay News) -- Higher total daily physical activity is associated with a reduced risk of developing Alzheimer's disease (AD) and with a lower rate of cognitive decline, according to research published online April 18 in Neurology.
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Basal Cell Carcinoma on Ear Significantly More Aggressive
WEDNESDAY, April 18 (HealthDay News) -- Basal cell carcinoma (BCC) on the ear is significantly more likely to be aggressive, and occurs more frequently in men, according to a study published in the May issue of the Journal of the American Academy of Dermatology.
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Numerous Genetic Variants Linked to Bone Mineral Density
WEDNESDAY, April 18 (HealthDay News) -- Pooling the results of numerous studies, 56 genetic variants associated with bone mineral density have been identified, of which 14 are associated with fracture risk, according to a study published online April 15 in Nature Genetics.
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Addicted Teens Benefit From 12-Step Meetings Attendance
WEDNESDAY, April 18 (HealthDay News) -- For adolescents with substance use disorder, attendance at 12-step programs is low, although more frequent attendance correlates with greater abstinence, according to a study published online April 16 in Alcoholism: Clinical & Experimental Research.
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Medicare Coverage Gap Leads to Drug Discontinuation
WEDNESDAY, April 18 (HealthDay News) -- Part D Medicare beneficiaries who do not have financial assistance during the coverage gap are at increased risk for cardiovascular drug discontinuation, according to research published online April 17 in Circulation: Cardiovascular Quality and Outcomes.
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Study Looks at Patient Perception of Harm During Cancer Care
WEDNESDAY, April 18 (HealthDay News) -- Cancer patients may often experience what they believe to be a preventable, harmful event during the diagnosis or treatment of their cancer, but rarely do they formally report these events, according to research published online April 16 in the Journal of Clinical Oncology.
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Omega-3 Supplements Don't Benefit Patients With MS
WEDNESDAY, April 18 (HealthDay News) -- Omega-3 (ω-3) fatty acid supplements do not improve disease activity in patients with relapsing-remitting multiple sclerosis (MS), according to a study published online April 16 in the Archives of Neurology.
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Testosterone Ups Exercise Capacity in Heart Failure
TUESDAY, April 17 (HealthDay News) -- Testosterone supplementation is associated with improved exercise capacity in patients with moderate-to-severe heart failure, according to a meta-analysis published online April 17 in Circulation: Heart Failure.
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New Fibrate Use Ups Serum Creatinine Levels in Elderly
TUESDAY, April 17 (HealthDay News) -- For elderly adults, new fibric acid derivative (fibrate) use is associated with an increase in serum creatinine levels, in hospitalizations for these levels, and in nephrologist consultations, according to a study published in the April 17 issue of the Annals of Internal Medicine.
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ICD-9 Codes Underestimate Statin-Linked Rhabdomyolysis
TUESDAY, April 17 (HealthDay News) -- Use of diagnostic codes, such as International Classification of Diseases -- Ninth Revision (ICD-9) codes, may result in misclassification of rare, adverse drug reactions (ADRs), including the risk of rhabdomyolysis from high-dose simvastatin, according to a research letter published in the April 18 issue of the Journal of the American Medical Association, a theme issue on comparative effectiveness research.
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Fewer Complications With IMRT for Prostate Cancer
TUESDAY, April 17 (HealthDay News) -- For patients with nonmetastatic prostate cancer, treatment with intensity-modulated radiation therapy (IMRT) is associated with fewer complications than proton therapy or conformal radiation therapy, according to a study published in the April 18 issue of the Journal of the American Medical Association, a theme issue on comparative effectiveness research.
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Evidence Lacking for Value of CKD Screening and Monitoring
TUESDAY, April 17 (HealthDay News) -- There is no evidence that screening and monitoring for chronic kidney disease (CKD) improves clinical outcomes, according to research published in the April 17 issue of the Annals of Internal Medicine.
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Preexposure Chemoprophylaxis Cuts HIV Infection at a Cost
TUESDAY, April 17 (HealthDay News) -- Models show daily oral preexposure chemoprophylaxis (PrEP) in the general population of men who have sex with men (MSM) could prevent a substantial number of HIV infections, but at a high cost, according to a study published in the April 17 issue of the Annals of Internal Medicine.
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Nutrition, Mobility Predict Early Death in Elderly Cancer Patients
TUESDAY, April 17 (HealthDay News) -- Low nutritional assessment scores, poor mobility, and advanced disease predict early death after chemotherapy initiation among elderly patients with cancer, according to a study published online April 16 in the Journal of Clinical Oncology.
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Rate Down But Unintentional Injury Still Top Cause of Death
TUESDAY, April 17 (HealthDay News) -- Although the unintentional injury death rate has declined over the last decade, it is still the leading cause of death among children and adolescents in the United States, according to a study published in the April 16 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
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2001 to 2006 Saw Increase in Mohs Surgery for Skin Cancer
TUESDAY, April 17 (HealthDay News) -- For Medicare beneficiaries, the rate of use of Mohs micrographic surgery (MMS) to treat nonmelanoma skin cancer (NMSC) doubled from 2001 through 2006, according to research published in the April issue of the Archives of Dermatology.
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Depressed Moms May Trigger Infant Night Waking
TUESDAY, April 17 (HealthDay News) -- Maternal depression and dysfunctional cognition impacts mothers' behavior at bedtime and may affect infant sleep, according to a study published online April 17 in Child Development.
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Epidural Steroid Shot May Offer Modest Benefit in Sciatica
TUESDAY, April 17 (HealthDay News) -- For adults with lumbosacral radiculopathy, epidural steroid injections may be beneficial for short-term pain relief and improvements in functional capacity, according to a study published in the April 17 issue of the Annals of Internal Medicine.
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Fast Food Salt Levels Vary Among Six Countries
MONDAY, April 16 (HealthDay News) -- High salt content in pizza, fried chicken, and other products served by multinational food chains varies substantially across six countries, and even incremental reductions of the seasoning could have a big impact on improving the health of the population, according to a study published online April 16 in CMAJ, the journal of the Canadian Medical Association.
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Pre-Pregnancy BMI Important Indicator of Offspring Obesity
MONDAY, April 16 (HealthDay News) -- Maternal gestational weight gain (GWG) during the first 20 weeks of pregnancy correlates with body mass index (BMI)-based overweight/obesity and abdominal obesity at age 16, but maternal pre-pregnancy BMI is a stronger indicator of offspring obesity, according to a study published in the May issue of BJOG: An International Journal of Obstetrics and Gynaecology.
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Immunization Pain Reduced Using the Five S's Technique
MONDAY, April 16 (HealthDay News) -- Use of the five S's intervention (swaddling, side/stomach position, shushing, swinging, and sucking) reduces pain scores and crying time following administration of routine immunizations for 2- and 4-month-old infants, according to a study published online April 16 in Pediatrics.
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Alcohol Use With Opioids Common Even Without Abuse Past
MONDAY, April 16 (HealthDay News) -- Alcohol or sedative use during chronic opioid therapy (COT) for non-cancer pain puts patients at risk for adverse events such as respiratory depression or sedation, and the risk of concurrent use of central nervous system (CNS) depressants is not limited to patients with a history of substance abuse, according to a study published in the March issue of The Journal of Pain.
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High SPF Sunscreens Assure Protection From Solar Rays
MONDAY, April 16 (HealthDay News) -- An application of water-resistant sunscreen with a sun protection factor (SPF) of 70 or higher adequately protects people against skin cancer and photodamage even when applied irregularly, according to a study published online April 1 in the Journal of the American Academy of Dermatology.
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Social Adversity Contributes to Obesity in Girls
MONDAY, April 16 (HealthDay News) -- Preschool-aged girls who experience higher cumulative social adversity at age 1 or age 3 are about twice as likely to exhibit early-onset obesity by age 5 as those without significant risk factors at either time point, according to research published online April 16 in Pediatrics.
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'Choking Game' Linked to Other Risk Behaviors in Young Teens
MONDAY, April 16 (HealthDay News) -- About 6 percent of Oregon male and female eighth-graders participate in the "choking game," an activity in which children apply pressure to the neck to limit oxygen and blood flow in the hopes of experiencing a euphoric feeling once the pressure is released and blood and oxygen rush back to the brain; and participation in this activity is linked to other risk behaviors, according to research published online April 16 in Pediatrics.
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IL-32 Expression Upregulated in Chronic Rhinosinusitis
MONDAY, April 16 (HealthDay News) -- Interleukin-32 (IL-32) mRNA expression is significantly higher in biopsies obtained from patients with chronic rhinosinusitis (CRS), compared to levels found in biopsies obtained from individuals without the condition, according to a study published online April 9 in Allergy.
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Calorie Cutting Needed to Meet Youth Obesity Goals
FRIDAY, April 13 (HealthDay News) -- In order for the nation to achieve Healthy People 2020 childhood obesity prevention goals, children on average would need to reduce their daily caloric intake by 64 calories, according to a study published in the May issue of the American Journal of Preventive Medicine.
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Crizotinib Treatment Lowers Total Testosterone Levels
FRIDAY, April 13 (HealthDay News) -- Men with non-small-cell lung cancer (NSCLC) treated with crizotinib exhibit rapid suppression of total testosterone (T) levels compared with those who do not receive crizotinib treatment, according to research published online April 4 in Cancer.
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Most Breast Cancer Survivors Experience Lasting Side Effects
FRIDAY, April 13 (HealthDay News) -- The majority of breast cancer survivors experience one or more treatment-related side effects, and the proportion remains stable at six years post-diagnosis, according to a study published in a special supplement to the April 15 issue of Cancer addressing the physical late effects of breast cancer treatment.
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Isomaltulose Doesn't Improve Glycemic Control in Diabetes
FRIDAY, April 13 (HealthDay News) -- For patients with type 2 diabetes, substitution of sucrose with isomaltulose is not associated with improved glycemic control (measured by hemoglobin A1c [HbA1c] levels) at 12 weeks, according to a study published online April 9 in Diabetes Care.
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Obesity Costs Are Higher Than Previous Estimates
FRIDAY, April 13 (HealthDay News) -- Obesity accounts for nearly 21 percent of U.S. health care costs, much higher than previously estimated, according to a study published in the January issue of the Journal of Health Economics.
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Sequencing Traditional Chinese Medicines Reveals Surprises
FRIDAY, April 13 (HealthDay News) -- DNA sequencing of traditional Chinese medicines (TCMs) using high-throughput sequencing (HTS) reveals that potentially toxic plant ingredients and traces of endangered animals are present, according to a study published online April 12 in PLoS Genetics.
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Pain Correlates Most Strongly With Disability in Hispanics With RA
FRIDAY, April 13 (HealthDay News) -- For Hispanic patients with rheumatoid arthritis (RA), self-reported pain correlates most strongly with disability, according to a study published online April 5 in Arthritis Care & Research.
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Many Women Still Report Drinking During Pregnancy
THURSDAY, April 12 (HealthDay News) -- A considerable proportion of women report continuing to drink during pregnancy, but biomarker tests indicate they are drinking at modest levels, according to a study published online April 6 in Alcoholism: Clinical & Experimental Research.
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Small Number of Genes Involved in X-Linked Ichthyosis
THURSDAY, April 12 (HealthDay News) -- Patients with X-linked recessive ichthyosis (XLRI) have altered expression in a small number of genes, and although moisturizer treatment improves dryness, it doesn't affect other biophysical properties or gene expression, according to a study published online April 5 in the British Journal of Dermatology.
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Risk of Sudden Cardiac Death Up for Black Patients With HTN
THURSDAY, April 12 (HealthDay News) -- Black patients with hypertension face a significantly increased risk of sudden cardiac death (SCD) compared with nonblack patients, even after adjusting for multiple confounding variables, according to a study published in the April issue of Heart Rhythm.
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Prolonged Inadequate Sleep Linked to Obesity and Diabetes
THURSDAY, April 12 (HealthDay News) -- Prolonged inadequate sleep at irregular times lowers the resting metabolic rate and leads to defects in pancreatic insulin secretion, increasing the risk for obesity and diabetes, according to a study published in the April 11 issue of Science Translational Medicine.
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Vitamin D3 Levels Not Linked to Academic Achievement
THURSDAY, April 12 (HealthDay News) -- Serum 25-hydroxyvitamin D (25[OH]D)3 concentrations are not associated with academic performance in children, according to a study published online April 9 in the Journal of Epidemiology & Community Health.
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U.S. Fertility Measures Largely Unchanged Since 2002
THURSDAY, April 12 (HealthDay News) -- Fertility measures for 15- to 44-year olds for 2006 to 2010 are similar to findings from 2002, according to an April 12 data brief issued by the National Center for Health Statistics (NCHS).
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Majority of Obese Adults Do Try to Lose Weight
THURSDAY, April 12 (HealthDay News) -- Nearly two-thirds of obese adults are trying to lose weight, and those that eat less fat, exercise more, and use prescription weight loss medications are more successful at losing weight, according to a study published online April 10 in the American Journal of Preventive Medicine.
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Role of Omega-3 in Secondary Prevention of CVD Questioned
THURSDAY, April 12 (HealthDay News) -- For patients with a history of cardiovascular disease (CVD), evidence is lacking for a secondary preventive effect of omega-3 fatty acid supplements, according to a meta-analysis published online April 9 in the Archives of Internal Medicine.
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Chronic Depression Patients Pick Acupuncture Over Counseling
THURSDAY, April 12 (HealthDay News) -- Patients with depression can be recruited from primary care to compare acupuncture with counseling and general practitioner (GP) care, according to a study published in the April issue of CNS Neurosciences & Therapeutics.
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Mentholated Cigarettes Linked to Increased Stroke Risk
THURSDAY, April 12 (HealthDay News) -- Mentholated cigarettes are associated with a significantly increased risk of stroke, particularly among women and non-African-American smokers, according to a letter published in the April 9 issue of the Archives of Internal Medicine.
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Gestational Age Affects Severity of Autism Symptoms
THURSDAY, April 12 (HealthDay News) -- Both preterm (<37 weeks) and post-term (>42 weeks) gestational age (GA) children with autistic spectrum disorder (ASD) display more severe symptoms compared with those born at a normal GA, according to research published online March 16 in the Journal of Autism and Developmental Disorders.
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Antidepressants Don't Worsen Parkinson's Symptoms
WEDNESDAY, April 11 (HealthDay News) -- The antidepressants paroxetine and venlafaxine extended release (XR) reduce depression without worsening motor function in patients with Parkinson's disease, according to a study published online April 11 in Neurology.
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Study Assesses Glucose Monitoring Trends in Tweens
WEDNESDAY, April 11 (HealthDay News) -- During the transition to adolescence, children with type 1 diabetes monitor their blood glucose less frequently, resulting in significant increases in HbA1c levels, according to research published online April 3 in Diabetes Care.
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Pattern of Disc Degeneration Impacts Low Back Pain
WEDNESDAY, April 11 (HealthDay News) -- Contiguous, multilevel disc degeneration (CMDD) is associated with increased likelihood of low back pain (LBP) and pain severity compared with skipped level disc degeneration (SLDD), according to a study published in the April 1 issue of Spine.
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Occupational Exposures Put Nurses at Risk of Miscarriage
WEDNESDAY, April 11 (HealthDay News) -- Nurses face an increased risk of spontaneous abortions during early pregnancy from occupational exposure to antineoplastic drugs and sterilizing agents, according to a study published in the April issue of the American Journal of Obstetrics & Gynecology.
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Eight-Item Classifier Accurately Distinguishes Autism
WEDNESDAY, April 11 (HealthDay News) -- The use of a short eight-item classifier identifies individuals with autism with high sensitivity and specificity, according to a study published online April 10 in Translational Psychiatry.
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Stroke Risk Much Higher If Sibling Has Had a Stroke
WEDNESDAY, April 11 (HealthDay News) -- Having a sibling who has had a stroke significantly increases the familial stroke risk by at least 60 percent, according to a study published online April 10 in Circulation: Cardiovascular Genetics.
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Mobile Stroke Units Halve Time to Treatment
WEDNESDAY, April 11 (HealthDay News) -- Diagnosis and treatment of stroke in patients at the scene of the emergency rather than at the hospital about halves the time to treatment, according to a study published online April 11 in The Lancet Neurology.
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Smoking Found to Be a Risk Factor for Barrett's Esophagus
WEDNESDAY, April 11 (HealthDay News) -- Cigarette smoking may be a modifiable risk factor for Barrett's esophagus, according to a study published in the April issue of Gastroenterology.
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STI Screening Improves With Free, Home-Based Testing
WEDNESDAY, April 11 (HealthDay News) -- The availability of free and home-based screening tests for sexually transmitted infections (STIs) is associated with a higher rate of screening completion, according to a study published in the April issue of the American Journal of Obstetrics & Gynecology.
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Perception of Breast Cancer Care Differs From Actual Care Quality
WEDNESDAY, April 11 (HealthDay News) -- The perception of care for women living in inner cities with newly diagnosed, early-stage breast cancer is dependent, in large part, on factors other than the actual quality of care provided, including the quality of the process of getting care, trust in the physician, and perceptions of racism, according to research published online April 9 in the Journal of Clinical Oncology.
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BMD Loss Occurs Early in Androgen Deprivation Therapy
WEDNESDAY, April 11 (HealthDay News) -- The highest average change in bone mineral density (BMD) occurs during early treatment of nonmetastatic, hormone-sensitive prostate cancer in men receiving intermittent androgen deprivation therapy (ADT), according to research published online April 9 in the Journal of Clinical Oncology.
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For Obese, Deep Organs Receive Lower Doses of Radiation
WEDNESDAY, April 11 (HealthDay News) -- For obese individuals, organs deep within the abdomen may receive lower doses of radiation than the organs of normal-weight individuals, with the same scanner operating parameters, according to a study published online April 5 in Physics in Medicine and Biology.
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More Gastro Events in Patients With Rheumatoid Arthritis
WEDNESDAY, April 11 (HealthDay News) -- The incidence of upper and lower gastrointestinal (GI) events is higher among patients with rheumatoid arthritis (RA), as is the risk of mortality due to GI events, when compared to individuals without RA, according to a study published online April 1 in the Journal of Rheumatology.
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Decision Aid for Chest Pain in ER Engages Patients
TUESDAY, April 10 (HealthDay News) -- Use of a decision aid, a visual patient education tool, helps chest pain patients become more engaged in their care and results in fewer admissions for observation and stress testing, without negatively impacting care outcomes, according to a study published online April 10 in Circulation: Cardiovascular Quality and Outcomes.
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Injectable Contraceptive Linked to Elevated Breast Cancer Risk
TUESDAY, April 10 (HealthDay News) -- Recent use of the injectable contraceptive depo-medroxyprogesterone acetate (DMPA) for 12 months or longer may approximately double the risk of breast cancer in young women, according to a study published online Feb. 27 in Cancer Research.
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Death Risk Similar With High-Dose Losartan, Candesartan
TUESDAY, April 10 (HealthDay News) -- For patients with heart failure, the use of high-dose losartan is not associated with an increased mortality risk compared with high-dose candesartan, according to a study published in the April 11 issue of the Journal of the American Medical Association.
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Increased Risk of Fatal Road Crashes on Tax Day in the U.S.
TUESDAY, April 10 (HealthDay News) -- There is a small, but significant, increase in fatal road crashes on tax day in the United States, according to a letter published in the April 11 issue of the Journal of the American Medical Association.
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ECG Abnormalities Add to Accuracy of CHD Risk Prediction
TUESDAY, April 10 (HealthDay News) -- Major and minor electrocardiographic (ECG) abnormalities are associated with an increased risk of coronary heart disease (CHD) events, particularly in elderly individuals, according to a study published in the April 11 issue of the Journal of the American Medical Association.
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Strategy of Offering Choice of CRC Screening Ups Adherence
TUESDAY, April 10 (HealthDay News) -- Adherence to colorectal cancer (CRC) screening varies based on the screening strategy, with adherence linked to patient preference and ethnicity/race, according to a study published in the April 9 issue of the Archives of Internal Medicine.
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Alternative Medicine Doesn't Affect Asthma Care in Children
TUESDAY, April 10 (HealthDay News) -- Complementary and alternative medicine (CAM) is not associated with adherence to pediatric asthma treatment, according to a study published online April 9 in Pediatrics.
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Insurers Should Screen Older Smokers for Lung Cancer
TUESDAY, April 10 (HealthDay News) -- Lung cancer screening with low-dose spiral computed tomography could be of substantial value in high-risk smoker populations over the age of 50, and commercial insurers should consider providing coverage for the screening, according to a study published in the April issue of Health Affairs.
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Mitochondrial Respiratory Capacity, Sperm Motility Linked
TUESDAY, April 10 (HealthDay News) -- Sperm with higher motility have increased mitochondrial respiratory capacity, according to a study published in the April issue of Urology.
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HPV Vaccine Side Effects Not Serious in Young Women
TUESDAY, April 10 (HealthDay News) -- Younger girls are more likely than adult women to report side effects after receiving the quadrivalent human papillomavirus (HPV4; Gardasil) vaccine, but the side effects are non-serious, according to a study published online Jan. 9 in the Journal of Women's Health.
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Frequent, Older Dental X-Rays Linked to Brain Cancer
TUESDAY, April 10 (HealthDay News) -- Frequent bitewing or panorex dental X-rays taken on previous generations of machines are linked to an increased risk of intracranial meningioma, according to a study published online April 10 in Cancer.
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Radiation Exposure High for Patients With GI Disorders
TUESDAY, April 10 (HealthDay News) -- Patients with inflammatory bowel disorders and other organic and functional gastrointestinal (GI) disorders are exposed to high levels of annual and cumulative diagnostic radiation, according to a study published in the March issue of Clinical Gastroenterology and Hepatology.
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High U.S. Cancer Care Costs Seem to Be Worth It
MONDAY, April 9 (HealthDay News) -- For patients with cancer in the United States, the value of additional survival gains have exceeded the additional costs of U.S. health spending compared with European counties, according to a study published in the April issue of Health Affairs.
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Economic, Health Indices Linked to Elevated Cholesterol
MONDAY, April 9 (HealthDay News) -- For patients with a history of hyperlipidemia, country-level economic and health system indices impact global-level variation in elevated cholesterol, according to a study published online April 9 in Circulation.
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Asymptomatic High-Risk Adults Often Have Pancreatic Lesions
MONDAY, April 9 (HealthDay News) -- Screening of asymptomatic high-risk individuals (HRIs) for pancreatic cancer often detects pancreatic lesions, many of which are proven or suspected neoplasms, according to a study published in the April issue of Gastroenterology.
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Urinary Incontinence Drugs Have Comparable Efficacy
MONDAY, April 9 (HealthDay News) -- Available pharmacotherapies for treating women with urinary incontinence (UI) produce comparable small benefits, according to research published online April 9 in the Annals of Internal Medicine.
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Variety of Fruits, Vegetables Linked to Lower Diabetes Risk
MONDAY, April 9 (HealthDay News) -- Eating a greater quantity of vegetables and a greater variety of fruits and vegetables (F&V) correlates with a reduced risk of type 2 diabetes (T2D), according to a study published online April 3 in Diabetes Care.
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Teen Alcohol Consumption Tied to Benign Breast Disease
MONDAY, April 9 (HealthDay News) -- Adolescent alcohol consumption is associated with increased risk of proliferative benign breast disease (BBD), which is a risk factor for breast cancer, and there is no evidence that adolescent folate intake provides a protective effect against alcohol-associated BBD, according to a study published online April 9 in Pediatrics.
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Two Novel Genetic Variants Linked to Childhood Obesity
MONDAY, April 9 (HealthDay News) -- Two new genetic variants have been found to be associated with childhood obesity, according to a study published online April 8 in Nature Genetics.
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Targeted Exercise Relieves Sciatica Pain
MONDAY, April 9 (HealthDay News) -- Active conservative symptom-guided therapy for severe sciatica can safely reduce pain and improve neurological function at a rate that matches or surpasses outcomes from common higher-cost surgical interventions, according to a Danish study published in the April 1 issue of Spine.
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Maternal Metabolic Disease Tied to Autism
MONDAY, April 9 (HealthDay News) -- Maternal metabolic conditions (MCs) increase the risk that a child will be born with a neurodevelopmental disorder, such as autism or developmental delay, according to a study published online April 9 in Pediatrics.
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Evidence Lacking for Sleep Length, Energy Metabolism Link
MONDAY, April 9 (HealthDay News) -- Short sleep duration may affect total daily energy expenditure or directly affect energy metabolism, although more study is required, according to a review published online March 22 in Obesity Reviews.
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Infection May Be Trigger for Venous Thromboembolism
MONDAY, April 9 (HealthDay News) -- Older adults recovering from an infection are at increased risk of being hospitalized for a venous thromboembolism (VTE), according to a study published online April 3 in Circulation.
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Report Highlights Child Deaths From Post-Surgery Codeine Use
MONDAY, April 9 (HealthDay News) -- Researchers have identified three previously unreported instances of severe opioid-induced toxicity in children following adenotonsillectomy for obstructive sleep apnea syndrome, according to a case report published online April 9 in Pediatrics.
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Statins Moderate Effect of Metformin on Prostate Cancer
MONDAY, April 9 (HealthDay News) -- For men with type 2 diabetes treated with metformin, prostate cancer (PCa) incidence varies depending on statin use, with a significantly reduced risk for patients taking a combination of metformin and statins, according to a study published online March 28 in Diabetes Care.
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Lumbar Spinal Stenosis Lowers Health-Related QoL
FRIDAY, April 6 (HealthDay News) -- Patients diagnosed with lumbar spinal stenosis (LSS) have a substantial burden of illness and reduced health-related quality of life (HRQL) compared to the general population, and their HRQL is compounded by associated comorbidities, according to a study published in the March issue of The Spinal Journal.
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Low Blood Adiponectin Predicts Future Asthma Risk in Women
FRIDAY, April 6 (HealthDay News) -- Middle-aged women with low blood adiponectin levels are about twice as likely to develop asthma, particularly if they smoke, according to a study published online April 6 in the American Journal of Respiratory and Critical Care Medicine.
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Treating Hepatic Encephalopathy Reduces Costs Due to MVAs
FRIDAY, April 6 (HealthDay News) -- For patients with minimal hepatic encephalopathy (MHE), diagnosis and treatment with lactulose reduces costs associated with motor vehicle accidents (MVAs), according to a study published in the April issue of Hepatology.
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Wire Grill Brush Bristles Pose Unexpected Danger
FRIDAY, April 6 (HealthDay News) -- For patients presenting with odynophagia or abdominal pain, physicians should consider the possibility of inadvertent wire brush bristle ingestion after eating grilled meat, according to a report published in the April issue of the American Journal of Roentgenology.
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Fetal Pesticide Exposure Affects Birth Weight, Gestation Length
FRIDAY, April 6 (HealthDay News) -- Fetal exposure to organophosphate (OP) insecticides can affect the length of gestation and birth weight, according to a study published online April 5 in Environmental Health Perspectives.
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Cognitive Therapy Has Little Effect on Psychosis Risk
FRIDAY, April 6 (HealthDay News) -- Although cognitive therapy does not reduce the risk of developing psychosis such as schizophrenia for at-risk individuals, it significantly reduces symptom severity for those who do develop psychosis, according to a study published online April 5 in BMJ.
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Toddlers Getting Little Daily Parent-Supervised Outdoor Play
FRIDAY, April 6 (HealthDay News) -- About half of all preschool-aged children do not have even one parent-supervised outdoor playtime per day, according to research published online April 2 in the Archives of Pediatrics & Adolescent Medicine.
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Antibiotics Safe and Effective to Treat Appendicitis
FRIDAY, April 6 (HealthDay News) -- Although surgery is standard practice for treating appendicitis, uncomplicated acute appendicitis can be safely and effectively treated with antibiotics, according to a meta-analysis published online April 5 in BMJ.
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Immunotherapy Tied to Lower Alzheimer's CSF Biomarkers
FRIDAY, April 6 (HealthDay News) -- For patients with mild-to-moderate Alzheimer's disease, immunotherapy treatment with the anti-β-amyloid (Aβ) monoclonal antibody bapineuzumab results in lower concentrations of two cerebrospinal fluid (CSF) biomarkers: total (T)-tau and phosphorylated (P)-tau, according to a study published online April 2 in the Archives of Neurology.
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Reduction Noted in Heart Rate Variability During Hot Flashes
FRIDAY, April 6 (HealthDay News) -- Women experiencing hot flashes have a significant reduction in heart rate variability during the hot flash, suggesting a role for the autonomic nervous system, according to a study published in the April issue of Menopause.
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Early Exposure to Interpersonal Trauma Harms Cognition
FRIDAY, April 6 (HealthDay News) -- Exposure to interpersonal trauma (IPT) in the first years of life is associated with decreased cognitive functioning in childhood, with exposure in the first two years particularly harmful, according to a study published online April 4 in the Journal of Epidemiology & Community Health.
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Methotrexate and Azathioprine Equally Efficacious for Eczema
FRIDAY, April 6 (HealthDay News) -- Methotrexate and azathioprine may be equally effective in treating severe atopic eczema in adults, according to a critical appraisal of a study published in the April issue of the British Journal of Dermatology.
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Physical Activity Predicts Functionality in Older Adults
FRIDAY, April 6 (HealthDay News) -- Physically active older adults experience significantly fewer functional limitations than more sedentary older adults, according to a study published online April 5 in the Journal of the American Geriatrics Society.
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Resistant Malaria Increasing on Thailand-Myanmar Border
THURSDAY, April 5 (HealthDay News) -- From 2001 to 2010, an increase was seen in artemisinin resistance in Plasmodium falciparum (P. falciparum) on the Thailand-Myanmar border, which was largely attributable to parasite genetics, according to a longitudinal study published online April 5 in The Lancet.
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Low-Energy-Density Diets Effective for Managing Weight
THURSDAY, April 5 (HealthDay News) -- There is an association between energy density and body weight, such that consumption of diets lower in energy density may be an effective strategy for weight management, according to study published online April 5 in the Journal of the Academy of Nutrition and Dietetics.
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Increased Breast Cancer Risk With False-Positive Test
THURSDAY, April 5 (HealthDay News) -- Women with false-positive mammogram tests remain at significantly higher risk of breast cancer for six or more years, compared to women with negative tests, but the size of the excess risk has decreased since the early 2000s, according to a study published online April 5 in the Journal of the National Cancer Institute.
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Asbestos Exposure Linked to Cardiovascular Death
THURSDAY, April 5 (HealthDay News) -- Occupational exposure to asbestos is associated with a higher risk of dying of cardiovascular disease, according to a study published online April 2 in Occupational & Environmental Medicine.
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Exercise Training Improves Cardiac Parameters in Lupus
THURSDAY, April 5 (HealthDay News) -- For inactive patients with systemic lupus erythematosus (SLE), a three-month exercise training program is associated with improved chronotropic reserve and heart rate recovery, according to a study published online March 21 in Arthritis Care & Research.
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Studies Investigate Role of De Novo Mutations in Autism
THURSDAY, April 5 (HealthDay News) -- The contribution of de novo mutations to the risk of autism spectrum disorders (ASDs) is complex, according to three sequencing studies published online April 4 in Nature.
Abstract - Sanders
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Flavonoid Intake May Protect Men Against Parkinson's
THURSDAY, April 5 (HealthDay News) -- Total flavonoid intake is significantly associated with a lower risk of Parkinson's disease (PD) in men, particularly the intake of anthocyanins and berries, according to a study published online April 4 in Neurology.
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Esophageal Cancer Surgery Has Lasting Effects on QoL
THURSDAY, April 5 (HealthDay News) -- Long-term survivors of esophageal cancer surgery who experience postoperative complications continue to experience long-lasting adverse effects on their health-related quality of life (HRQL), according to a study published online April 2 in the Journal of Clinical Oncology.
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Prenatal Antipsychotics Impact Infant Neuromotor Function
THURSDAY, April 5 (HealthDay News) -- The use of prescribed antipsychotics during pregnancy may result in significantly lower neuromotor performance in 6-month-old infants, according to a study published online April 2 in the Archives of General Psychiatry.
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New Guidelines Issued for Rheumatoid Arthritis Treatment
THURSDAY, April 5 (HealthDay News) -- The 2008 American College of Rheumatology (ACR) guidelines for the treatment of rheumatoid arthritis (RA) have been updated for 2012, according to a special article published in the May issue of Arthritis Care & Research.
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Medical Malpractice Claims Incur Substantial Defense Costs
WEDNESDAY, April 4 (HealthDay News) -- Defense costs for medical malpractice claims vary among specialties and are higher for claims that result in indemnity payments, according to a letter published in the April 5 issue of the New England Journal of Medicine.
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Cancer Diagnosis Linked to Higher Immediate Suicide Risk
WEDNESDAY, April 4 (HealthDay News) -- A recent cancer diagnosis is associated with a higher risk of suicide and death from cardiovascular causes, with the risk being highest in the weeks after diagnosis, according to a study published in the April 5 issue of the New England Journal of Medicine.
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Antibodies to HIV-1 Proteins Impact Vaccine Efficacy
WEDNESDAY, April 4 (HealthDay News) -- Antibodies to HIV-1 proteins may play a role in the efficacy of HIV-1 vaccination, according to a study published in the April 5 issue of the New England Journal of Medicine.
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End-of-Life Decline of Cognitive Functions Are Correlated
WEDNESDAY, April 4 (HealthDay News) -- In the last years of life, cognitive abilities decline rapidly, with a strong correlation between different functions; and cognitive activity is associated with cognitive function and predictive of cognitive decline, according to two studies published online April 4 in Neurology.
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Diagnostic Coding May Skew Pneumonia Outcomes Data
WEDNESDAY, April 4 (HealthDay News) -- The decline in pneumonia-related hospitalizations and associated inpatient deaths seen in 2003 to 2009 may be a result of diagnostic coding, rather than an actual improvement in outcomes, according to a study published in the April 4 issue of the Journal of the American Medical Association.
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Metal-on-Metal Bearing Not Linked to Cancer Incidence
WEDNESDAY, April 4 (HealthDay News) -- Hip replacements with metal-on-metal bearing surfaces do not seem to be associated with cancer incidence, according to study published online April 3 in BMJ.
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Alcohol, Drug Use Prevalent Among U.S. Adolescents
WEDNESDAY, April 4 (HealthDay News) -- Alcohol and drug use is prevalent among teens, with the median age of alcohol and drug abuse occurring during adolescence, according to a study published in the April issue of the Archives of General Psychiatry.
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Importance of Diabetes Genetic Variants Unclear
WEDNESDAY, April 4 (HealthDay News) -- Genetic variants associated with type 2 diabetes that affect glucagon-like peptide 1 (GLP-1) are not associated with GLP-1 levels or GLP-1-induced insulin secretion in healthy individuals, according to a study published online March 28 in Diabetes.
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Childhood Cancer Survivors at Risk for Cardiac Events
WEDNESDAY, April 4 (HealthDay News) -- Childhood cancer survivors (CCSs) treated with anthracyclines and/or cardiac irradiation have a higher risk of developing symptomatic cardiac events (CEs) in the long term, according to a study published online April 2 in the Journal of Clinical Oncology.
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Antibiotic-Resistant S. aureus Found in Many Ambulances
WEDNESDAY, April 4 (HealthDay News) -- Antibiotic-resistant strains of Staphylococcus aureus (S. aureus) are found in the majority of advanced life support (ALS) ambulances in the Chicago area, according to a study published in the April issue of the American Journal of Infection Control.
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Neupro Approved for Advanced Parkinson's and Restless Leg Syndrome
TUESDAY, April 3 (HealthDay News) -- The Neupro (rotigotine) transdermal system has been approved by the U.S. Food and Drug Administration to treat advanced Parkinson's disease and moderate-to-severe restless leg syndrome, the Belgian drug maker UCB said Tuesday in a news release.
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Fluoroquinolone Use Linked to Retinal Detachment
TUESDAY, April 3 (HealthDay News) -- The use of the oral fluoroquinolone antibiotics is associated with an increased risk of retinal detachment, although the absolute risk is small, according to a study published in the April 4 issue of the Journal of the American Medical Association.
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Mammogram Plus MRI or Ultrasound Catches More Cancer
TUESDAY, April 3 (HealthDay News) -- The addition of an ultrasound or magnetic resonance imaging (MRI) to annual mammography results in a higher rate of detection of incident breast cancers, according to a study published in the April 4 issue of the Journal of the American Medical Association.
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Obesity Epidemic in U.S. Worse Than Previously Thought
TUESDAY, April 3 (HealthDay News) -- The body mass index (BMI) substantially underdiagnoses obesity when compared to the dual-energy X-ray absorptiometry (DXA) scan, a direct simultaneous measure of body fat, muscle mass, and bone density, according to a study published online April 2 in PLoS One.
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Waist Measurements Specify Lipid, BP Levels in Obese Teens
TUESDAY, April 3 (HealthDay News) -- Waist measures (waist circumference and waist-to-height ratio [WHtR]) are associated with lipid and blood pressure levels, with increased WHtR linked to worsened lipid profile and hypertension in obese adolescents, according to a study published online April 2 in the Archives of Pediatrics & Adolescent Medicine.
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Heavy Baby Girls at Future Risk of Cardiometabolic Disease
TUESDAY, April 3 (HealthDay News) -- Heavier baby girls are at increased risk for developing diabetes and cardiovascular disease at age 17 years than are overweight baby boys, according to a study published online March 22 in the Journal of Clinical Endocrinology & Metabolism.
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More Than 40 Percent of Patients With RA Are Inactive
TUESDAY, April 3 (HealthDay News) -- More than 40 percent of patients with rheumatoid arthritis are inactive, with lack of motivation and lack of belief in physical activity strongly related to inactivity, according to a study published in the April issue of Arthritis Care & Research.
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Sleep Apnea, Snorting Linked to Probable Major Depression
TUESDAY, April 3 (HealthDay News) -- Sleep apnea and frequent snorting/stopping breathing during sleep, but not snoring, are associated with probable major depression, according to a study published in the April issue of SLEEP.
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Cervical Pessary Significantly Reduces Risk of Preterm Birth
TUESDAY, April 3 (HealthDay News) -- For women with a short cervix, use of a cervical pessary significantly reduces the risk of spontaneous delivery before 34 weeks, according to a randomized trial published online April 3 in The Lancet.
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Inflammatory Regulation Plays Role in Stress, Illness Link
TUESDAY, April 3 (HealthDay News) -- People under chronic stress have glucocorticoid receptor resistance (GCR), which is linked to increased risk of illness, according to research published online April 2 in the Proceedings of the National Academy of Sciences.
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Study Estimates Overdiagnosis From Mammography Screening
TUESDAY, April 3 (HealthDay News) -- Implementation of a mammography screening program leads to a substantial amount of overdiagnosis, according to a study published in the April 3 issue of the Annals of Internal Medicine.
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Most Americans Getting Adequate Amounts of Vitamins, Nutrients
MONDAY, April 2 (HealthDay News) -- Most people in the United States are getting adequate nutrition, but some groups experience lower levels of vital nutrients than that which is recommended for good health, according to the Second National Report on Biochemical Indicators of Diet and Nutrition released April 2 by the U.S. Centers for Disease Control and Prevention.
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Serious Eye Disease Linked to Bisphosphonate Use
MONDAY, April 2 (HealthDay News) -- First-time users of oral bisphosphonates have an increased risk of both uveitis and scleritis compared with nonusers, according to a study published online April 2 in CMAJ, the journal of the Canadian Medical Association.
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Guidelines Improve Outcomes in Nonshockable Cardiac Arrest
MONDAY, April 2 (HealthDay News) -- Implementation of the latest American Heart Association (AHA) resuscitation guidelines, which eliminate "stacked" shocks and emphasize chest compressions, results in significantly improved outcomes for patients experiencing nonshockable out-of-hospital cardiac arrest (OHCA), according to a study published online April 2 in Circulation.
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School Environment Has Little Effect on Teen Mental Health
MONDAY, April 2 (HealthDay News) -- There is limited evidence that the school environment impacts adolescent mental health, according to a review published online April 2 in Pediatrics.
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In Taiwan, Diabetes Linked to Increased Parkinson's Risk
MONDAY, April 2 (HealthDay News) -- Individuals with diabetes in Taiwan have a significantly increased risk of Parkinson's disease (PD), which is robust across most age and gender stratifications, according to a study published online March 19 in Diabetes Care.
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Operator Sleep Deprivation Does Not Adversely Affect PCI
MONDAY, April 2 (HealthDay News) -- Percutaneous coronary intervention (PCI) performed in the middle of the night does not impact the same operator's ability to perform PCI the next day, according to a study published online March 30 in Catheterization and Cardiovascular Interventions.
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Melanoma Incidence Increasing Among Young Adults
MONDAY, April 2 (HealthDay News) -- From 1970 to 2009, there was an increase in the incidence of melanoma among young adults, particularly females, according to a study published in the April issue of the Mayo Clinic Proceedings.
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Six Developmental Trajectories ID'd in Children With Autism
MONDAY, April 2 (HealthDay News) -- Six longitudinal developmental trajectories have been identified among children with autism, with significant heterogeneity seen in developmental pathways within these trajectories, according to a study published online April 2 in Pediatrics.
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More Complications After Thyroid Surgery in Elderly
MONDAY, April 2 (HealthDay News) -- Advanced age is a risk factor for complications after thyroidectomy, according to a study published online March 14 in the Journal of Clinical Endocrinology & Metabolism.
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Maternal Caffeine Intake Doesn't Affect Infant Sleep
MONDAY, April 2 (HealthDay News) -- Heavy caffeine consumption by nursing mothers does not increase the number of nighttime awakenings in 3-month-old infants, according to a study published online April 2 in Pediatrics.
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Malodorous Urine Often Reported for Infants With UTI
MONDAY, April 2 (HealthDay News) -- Parental reports of malodorous urine increase the likelihood of a diagnosis of a urinary tract infection (UTI) in young children being evaluated for a suspected infection, according to a study published online April 2 in Pediatrics.
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