December 2012 Briefing - Family Practice

Here are what the editors at HealthDay consider to be the most important developments in Family Practice for December 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Little Change in Global Infertility Rates Since 1990

MONDAY, Dec. 31 (HealthDay News) -- Infertility rates worldwide are similar to those in 1990, though the number of couples affected by infertility rose to nearly 50 million in 2010 due to population growth, according to a study published online Dec. 18 in PLOS Medicine.

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Type of Involvement in Gaming Impacts Perceived Social Support

MONDAY, Dec. 31 (HealthDay News) -- The level of psychological involvement in gaming determines the measure of a player's perceived social support, according to a study published in the current issue of Society & Leisure.

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Primary Care Physicians Perform Well on Diabetes Care Measures

FRIDAY, Dec. 28 (HealthDay News) -- Compared to covering physicians or midlevel providers, primary care physicians (PCPs) perform better on multiple critical process measures for diabetes care, according to a study published online Dec. 10 in Diabetes Care.

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Low Insulin Secretion Tied to Depressive Symptoms in Women

FRIDAY, Dec. 28 (HealthDay News) -- Middle-aged women with insulin secretion levels in the lowest quintile appear to have more than twice the risk of developing new-onset depressive symptoms compared with those with higher insulin secretion levels, according to research published online Dec. 10 in Diabetes Care.

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Recent U.S. Food-Linked Listeriosis Outbreaks Shorter

FRIDAY, Dec. 28 (HealthDay News) -- Compared with earlier outbreaks, more recent food-associated listeriosis outbreaks in the United States have been shorter and affected fewer people, according to research published online Dec. 12 in Emerging Infectious Diseases.

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Elevated C-Reactive Protein Linked to Distress, Depression

FRIDAY, Dec. 28 (HealthDay News) -- Elevated plasma levels of C-reactive protein (CRP) are associated with psychological distress and depression in the general population, according to a study published online Dec. 24 in the Archives of General Psychiatry.

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Sustained Virological Response Lowers Mortality Risk in Hep C

FRIDAY, Dec. 28 (HealthDay News) -- Sustained virological response (SVR) is associated with lower all-cause mortality in patients with chronic hepatitis C virus (HCV) and advanced hepatic fibrosis, according to a study published in the Dec. 26 issue of the Journal of the American Medical Association.

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Inpatient Resource Use Up for Children With Chronic Illness

FRIDAY, Dec. 28 (HealthDay News) -- Children with chronic conditions, particularly conditions affecting two or more body systems, increasingly use more resources when hospitalized than those without chronic conditions, according to a study published online Dec. 24 in the Archives of Pediatrics & Adolescent Medicine.

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Weight-Based Victimization Common Among Heavy Teens

FRIDAY, Dec. 28 (HealthDay News) -- Weight loss treatment-seeking adolescents frequently report weight-based victimization (WBV) at school, which is perpetrated by adults as well as peers and friends, according to a study published online Dec. 24 in Pediatrics.

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Dietary PA/OA Fat Ratio May Affect T2DM Risk in Women Only

FRIDAY, Dec. 28 (HealthDay News) -- A diet low in palmitic acid (PA) and high in oleic acid (OA) improves insulin sensitivity and is associated with lower levels of markers of metabolic and oxidative stress in women only, according to a study published online Dec. 13 in Diabetes.

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Limited Value for Pap Tests in Endometrial Cancer Recurrence

FRIDAY, Dec. 28 (HealthDay News) -- For women who have undergone a hysterectomy for endometrial cancer, abnormal Papanicolaou (Pap) test results do not aid in diagnosing recurrent disease, according to a study published in the January issue of Obstetrics & Gynecology.

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Urine Biomarkers May Help Diagnose Kawasaki Disease

FRIDAY, Dec. 28 (HealthDay News) -- Proteins present in urine exhibit excellent diagnostic performance for Kawasaki disease, according to a study published online Dec. 20 in EMBO Molecular Medicine.

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High Risk of Pulmonary Embolism Seen in Severe Asthma

FRIDAY, Dec. 28 (HealthDay News) -- Patients with asthma are at higher risk of pulmonary embolism, particularly if the asthma is severe or they take oral corticosteroids, according to a study published online Dec. 20 in the European Respiratory Journal.

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Teen Vitamin D Intake Not Related to Adult RA or SLE Risk

THURSDAY, Dec. 27 (HealthDay News) -- Dietary vitamin D intake during adolescence does not appear to be associated with the risk of adult-onset rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE), according to research published in the December issue of Arthritis Care & Research.

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Indicators Show Little Change in Overuse of Ambulatory Care

THURSDAY, Dec. 27 (HealthDay News) -- In the United States from 1999 to 2009, the delivery of underused care in the ambulatory setting improved, but fewer changes were seen in inappropriate care, according to a study published online Dec. 24 in the Archives of Internal Medicine.

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MRI Fairly Accurate As Surrogate for CSF Biomarkers

THURSDAY, Dec. 27 (HealthDay News) -- Magnetic resonance imaging (MRI) is a fairly accurate screening tool for distinguishing between Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD), according to a study published online Dec. 26 in Neurology.

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Cancer Screening Goals Not Being Met by General Population

THURSDAY, Dec. 27 (HealthDay News) -- In the United States, the general population only meets the recommended cancer screening goals for colorectal cancer, while cancer survivors meet all requirements except for cervical cancer screening, according to a study published online Dec. 27 in Frontiers in Cancer Epidemiology and Prevention.

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FDA Approves Juxtapid for Rare Cholesterol Disorder

THURSDAY, Dec. 27 (HealthDay News) -- The U.S. Food and Drug Administration has approved the orphan drug Juxtapid (lomitapide) for patients with homozygous familial hypercholesterolemia (HoFH), for use in combination with a low-fat diet and other lipid lowering treatments, according to a Dec. 26 press release.

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Review: Poor Outcomes With Blood Transfusion in MI

THURSDAY, Dec. 27 (HealthDay News) -- For patients with acute myocardial infarction, a strategy of blood transfusion is associated with increased all-cause mortality and subsequent myocardial infarction compared with a strategy of no transfusion, according to a meta-analysis published online Dec. 24 in the Archives of Internal Medicine.

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Imaging Widely Used in Presumed Pediatric Appendicitis

THURDAY, Dec. 27 (HealthDay News) -- Most children with presumed appendicitis undergo preoperative computed tomography (CT) and ultrasound imaging before surgery, with significant variation by hospital type and patient sex, according to research published online Dec. 24 in Pediatrics.

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Understanding of Infantile Hemangiomas Is Improving

THURSDAY, Dec. 27 (HealthDay News) -- Improved understanding of the pathogenesis of infantile hemangiomas (IHs) is leading to better treatment options, according to a review published online Dec. 24 in Pediatrics.

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Fewer Than a Quarter Call 911 During Acute Heart Problem

THURSDAY, Dec. 27 (HealthDay News) -- During acute coronary syndromes, fewer than one-quarter of patients call 911, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

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Prophylactic Options Compared for Women With BRCA1/2

THURSDAY, Dec. 27 (HealthDay News) -- The results of a simulation model suggest that, when quality of life is considered, prophylactic bilateral salpingectomy with delayed oophorectomy may be an acceptable alternative to bilateral salpingo-oophorectomy for women with BRCA mutations, according to research published in the January issue of Obstetrics & Gynecology.

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Early Menopause Tied to Greater Type 2 Diabetes Risk

THURSDAY, Dec. 27 (HealthDay News) -- Women who experience early menopause have a greater risk of type 2 diabetes, according to a study published online Dec. 10 in Diabetes Care.

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Reports of Child Maltreatment Down in 2011

WEDNESDAY, Dec. 26 (HealthDay News) -- The number of child neglect and abuse cases reported in the United States dropped in 2011, with an estimated 681,000 unique victims, according to the Child Maltreatment 2011 report.

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Fertility Drugs Not Linked to Uterine Cancer Recurrence

WEDNESDAY, Dec. 26 (HealthDay News) -- For women who undergo fertility-sparing treatment for uterine cancer, subsequent use of fertility drugs is not associated with a higher incidence of cancer recurrence, according to research published in the January issue of Obstetrics & Gynecology.

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Almost Half of Children With Food Allergy Report Being Bullied

WEDNESDAY, Dec. 26 (HealthDay News) -- For children with food allergy, bullying is common, and correlates with decreased quality of life and increased distress for children and their parents, according to a study published online Dec. 24 in Pediatrics.

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Lower Developmental Scores at Age 3 Seen in Plagiocephaly

WEDNESDAY, Dec. 26 (HealthDay News) -- Preschool-aged children with deformational plagiocephaly (DP) have lower scores on a measure of child development than unaffected controls, according to a study published online Dec. 24 in Pediatrics.

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Pre-Consult Genitourinary Exams Performed Infrequently

WEDNESDAY, Dec. 26 (HealthDay News) -- Initial genitourinary (GU) physical examinations are performed in less than a third of cases prior to requesting a urologic consultation, and this rate is affected by patient age and sex, according to research published in the December issue of Urology.

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C-Peptide Levels May Predict Mortality in Angiography Patients

WEDNESDAY, Dec. 26 (HealthDay News) -- Higher levels of C-peptide, a pro-insulin cleavage product, is associated with all-cause and cardiovascular mortality in patients undergoing coronary angiography, according to a study published online Nov. 30 in Diabetes Care.

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Topics of Sibling Conflict Have Distinct Effects on Teens

TUESDAY, Dec. 25 (HealthDay News) -- For adolescents, each underlying topic of sibling conflict has a distinct impact on their emotional adjustment, according to a study published online Dec. 20 in Child Development.

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Small Survival Advantage Noted for Olympic Athletes

TUESDAY, Dec. 25 (HealthDay News) -- Olympic athletes have a small survival advantage, with no significant difference in the mortality risk based on the level of exercise intensity variation of each discipline, according to two studies published Dec. 13 in BMJ.

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Sit and Rise Test Score Inversely Linked to Mortality

MONDAY, Dec. 24 (HealthDay News) -- For adults aged 51 to 80 years, the ability to sit and rise from the floor without support (hand/knee) is associated with improved survival, according to a study published online Dec. 13 in the European Journal of Preventive Cardiology.

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Internet Use Cuts Cancer Fatalism in Poorly Educated

MONDAY, Dec. 24 (HealthDay News) -- For adults with average or lower than average education or health knowledge, use of the Internet can reduce cancer fatalism, according to a study published in the December issue of the Journal of Communication.

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FDA Recommends Against Drug to Treat Chronic Fatigue Syndrome

FRIDAY, Dec. 21 (HealthDay News) -- A U.S. Food and Drug Administration advisory committee on Thursday recommended against approval of the first proposed drug to treat chronic fatigue syndrome (CFS), intravenous Ampligen (rintatolimod).

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Varizig Approved to Reduce Chickenpox Symptoms

FRIDAY, Dec. 21 (HealthDay News) -- Varizig (varicella zoster immune globulin) has been approved by the U.S. Food and Drug Administration to minimize chickenpox symptoms when administered within four days of exposure to the virus that causes the disease.

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FDA Expands Tamiflu Use to Treat Babies Under 1 Year Old

FRIDAY, Dec. 21 (HealthDay News) -- Tamiflu (oseltamivir) can now be given to children as young as 2 weeks old under an expanded approval announced Friday by the U.S. Food and Drug Administration.

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ACP Pledges to Try and End Firearms-Linked Death, Injuries

FRIDAY, Dec. 21 (HealthDay News) -- In the wake of the Dec. 14 tragic shooting in Newtown, Conn., the American College of Physicians (ACP) has pledged to play a part in ending recurring firearm-related deaths and injuries, according to an ACP statement published Dec. 20.

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Familial Cancer Risk Not Limited to Parents' Early-Onset Cancer

FRIDAY, Dec. 21 (HealthDay News) -- For many cancers, the familial risks of cancer are seen in offspring whose parents received a diagnosis of concordant cancer at all ages, although the highest risk is seen for those diagnosed at an early age, according to a study published online Dec. 20 in BMJ.

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Children Eat More Fruits and Vegetables at Family Meals

FRIDAY, Dec. 21 (HealthDay News) -- Eating meals together as a family leads to significantly higher consumption of fruits and vegetables for children, according to a study published online Dec. 19 in the Journal of Epidemiology & Community Health.

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ACOG: IOM's Gestational Weight Gain Guide Is Basis for Practice

FRIDAY, Dec. 21 (HealthDay News) -- The Institute of Medicine's (IOM) 2009 guidelines on gestational weight gain should serve as a basis for clinical practice, according to a Committee Opinion published by the American College of Obstetricians and Gynecologists (ACOG) in the January issue of Obstetrics & Gynecology.

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Motor Vehicle Incidents Common in Medical Residents

FRIDAY, Dec. 21 (HealthDay News) -- During training, internal medicine residents commonly experience motor vehicle incidents, including crashes and near misses, but less commonly experience blood and body fluid (BBF) exposures, according to research published in the December issue of the Mayo Clinic Proceedings.

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Longitudinal Algorithm May Detect Ovarian Cancer Earlier

FRIDAY, Dec. 21 (HealthDay News) -- Compared with a single-threshold (ST) rule, a parametric empirical Bayes (PEB) longitudinal screening algorithm can identify ovarian cancer earlier and at a lower concentration of CA125, according to research published online Dec. 17 in the Journal of Clinical Oncology.

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High Perceived Stress Related to Incident CHD

FRIDAY, Dec. 21 (HealthDay News) -- High perceived stress is associated with a moderate 27-percent increased risk of incident coronary heart disease (CHD), according to the results of a meta-analysis published in the Dec. 15 issue of The American Journal of Cardiology.

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Upper Lumbar Disc Space Related to Hip Pain

FRIDAY, Dec. 21 (HealthDay News) -- Disc space narrowing at disc levels L1/L2 and L2/L3, visible on lumbar radiographs, may help to identify hip pain patients whose pain originates in the lumbar spine, according to research published in the November issue of the European Spine Journal.

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Standards of Medical Care in Diabetes Released for 2013

FRIDAY, Dec. 21 (HealthDay News) -- Updated evidence for diabetes care, including guidelines for self-monitoring glucose, new blood pressure targets, and other aspects of care, are presented in a major position statement from the American Diabetes Association (ADA), "Standards of Medical Care in Diabetes," published as a supplement to the January issue of Diabetes Care.

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Data Suggest Smoking Doesn't Impact RA Treatment Response

THURSDAY, Dec. 20 (HealthDay News) -- For patients with early rheumatoid arthritis (RA), smoking status does not impact treatment response to early combination therapy or initial methotrexate treatment with step-up therapy, according to a study published in the December issue of Arthritis Care & Research.

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Fatty Acids Don't Reduce Atrial Fibrillation Recurrence

THURSDAY, Dec. 20 (HealthDay News) -- Polyunsaturated fatty acids (n-3 PUFA) do not reduce the recurrence of atrial fibrillation (AF), according to a study published online Dec. 19 in the Journal of the American College of Cardiology.

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FDA: Pradaxa Not for Patients With Mechanical Heart Valves

THURSDAY, Dec. 20 (HealthDay News) -- Pradaxa (dabigatran etexilate mesylate) should not be used to prevent stroke or blood clots (major thromboembolic events) in patients with mechanical heart valves, according to a Dec. 19 safety announcement issued by the U.S. Food and Drug Administration.

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AAP to Obama: Make Safety of Children a National Focus

THURSDAY, Dec. 20 (HealthDay News) -- Responding to the Dec. 14 tragic shooting in Newtown, Conn., the American Academy of Pediatrics (AAP) has expressed a willingness to work together with the government to ensure the health and safety of children, according to a letter written from the AAP to President Obama.

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In U.S., Only 3.3 Percent Have Ideal Cardiovascular Health

THURSDAY, Dec. 20 (HealthDay News) -- Only 3.3 percent of Americans are in ideal cardiovascular health, with considerable between-state variation noted, according to research published online Dec. 19 in the Journal of the American Heart Association.

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Overall, Teen Drug Use Remains Steady in 2012

THURSDAY, Dec. 20 (HealthDay News) -- Overall, illicit drug use among U.S. teenagers was unchanged over the past year; however, from 2007 to 2012, there has been an increase in illicit drug use among 12th graders and an increase in the use of marijuana among 10th graders, according to a report issued Dec. 19 by the White House Office of National Drug Control Policy.

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High-Nutrient Dense Snack Cuts Calorie Intake for Children

THURSDAY, Dec. 20 (HealthDay News) -- Giving children a high-nutrient dense (HND) snack of cheese and vegetables reduces calorie intake compared with a non-nutrient dense (NND) snack, according to a study published online Dec. 17 in Pediatrics.

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Metformin Treatment Beneficial for Obese Children, Teens

THURSDAY, Dec. 20 (HealthDay News) -- Obese children and adolescents treated with twice-daily metformin have significantly improved body mass index standard deviation scores (BMI-SDS), fasting glucose, and other metabolic risk factors, according to research published online Nov. 21 in the Journal of Clinical Endocrinology & Metabolism.

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Spanish Registry IDs Predictors of Low Back Pain Improvement

THURSDAY, Dec. 20 (HealthDay News) -- For patients with acute or chronic low back pain (LBP), predictors have been identified for clinically relevant improvements in LBP, pain down the leg (LP), and disability at three months, according to research published in the November issue of The Spine Journal.

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Alzheimer's Trial Participation Linked to Study Partner

THURSDAY, Dec. 20 (HealthDay News) -- Patients with Alzheimer's disease (AD) with non-spouse caregivers participate less frequently in AD clinical trials, according to research published online Dec. 19 in Neurology.

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Meds Adherence Self-Report Valid in Type 2 Diabetes

THURSDAY, Dec. 20 (HealthDay News) -- Self-reported measures of medication adherence in adults with type 2 diabetes are valid, although some self-reports are moderated by depression, according to a study published online Nov. 30 in Diabetes Care.

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10th Annual Report Shows Gaps in Emergency Preparedness

WEDNESDAY, Dec. 19 (HealthDay News) -- There seem to be considerable gaps in the ability of states to respond to health emergencies, according to the 10th annual report, Ready or Not? Protecting the Public from Diseases, Disasters, and Bioterrorism, published Dec. 19 by the Trust for America's Health.

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Substantial Morbidity, Mortality From Fungus-Tainted Steroid

WEDNESDAY, Dec. 19 (HealthDay News) -- Considerable morbidity and mortality resulted from the use of three lots of fungus-contaminated methylprednisolone acetate, recalled by the pharmacy, according to a preliminary report published online Dec. 19 in the New England Journal of Medicine.

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Vertex Announces Boxed Warning on Hepatitis C Drug

WEDNESDAY, Dec. 19 (HealthDay News) -- In the wake of multiple deaths, the oral hepatitis C drug telaprevir (Incivek) will now carry a boxed warning, according to a statement released Dec. 19 by Vertex Pharmaceuticals.

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Implications of Employer Contraceptive Coverage Explored

WEDNESDAY, Dec. 19 (HealthDay News) -- The Affordable Care Act's (ACA) provision of preventive services, including contraceptive methods, has raised religious objections and complex legal issues for secular employers, according to a perspective piece published online Dec. 19 in the New England Journal of Medicine.

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Secondhand Smoke Affects Many Living in Multiunit Housing

WEDNESDAY, Dec. 19 (HealthDay News) -- Many residents of multiunit housing (MUH) experience secondhand smoke (SHS) infiltration, despite having smoke-free home rules, according to a study published online Dec. 17 in Nicotine & Tobacco Research.

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Amoxicillin of Little Benefit in Lower-Respiratory Infection

WEDNESDAY, Dec. 19 (HealthDay News) -- In cases of lower-respiratory-tract infection when pneumonia is not suspected, amoxicillin provides little symptomatic benefit, according to a study published online Dec. 19 in The Lancet Infectious Diseases.

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Pediatric Ingestions of Caustic Substances Down in 2009

WEDNESDAY, Dec. 19 (HealthDay News) -- Hospitalizations of children ingesting caustic substances such as lye were fewer in 2009 than previous estimates, according to a study published in the December issue of the Archives of Otolaryngology -- Head & Neck Surgery.

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Childhood Abuse Tied to Adult-Onset Asthma in Black Women

WEDNESDAY, Dec. 19 (HealthDay News) -- There is a positive association between adult-onset asthma and physical abuse in childhood among African-American women, according to a study published online Dec. 7 in the Journal of Allergy and Clinical Immunology.

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Many Docs Use Social Media to Find, Share Medical Data

WEDNESDAY, Dec. 19 (HealthDay News) -- Most physicians use social media on at least a weekly basis, and report that it improves the quality of patient care they deliver, according to a study published in the September/October issue of the Journal of Medical Internet Research.

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Lost Productivity ~20 Percent of Cancer Costs for Employees

WEDNESDAY, Dec. 19 (HealthDay News) -- Productivity losses due to disability days for employees being treated for cancer represent about 20 percent of the overall health care expenditure, according to a study published in the December issue of the Journal of Occupational and Environmental Medicine.

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HPV Diagnosis at Older Age May Be 'Latent' Infection Reactivation

TUESDAY, Dec. 18 (HealthDay News) -- Among U.S. women with a sexual debut before the sexual revolution, a lower cumulative probability of human papillomavirus (HPV) infection may be masking an age-related increase in HPV reactivation, according to a study published online Dec. 12 in the Journal of Infectious Diseases.

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Two Distinct High-Risk Diabetes Populations ID'd in Children

TUESDAY, Dec. 18 (HealthDay News) -- Children with high-risk A1C (hrA1C) and impaired fasting glucose (IFG) define different populations, with differentially increased risk markers, according to research published online Nov. 27 in Diabetes Care.

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Intensive Lifestyle Changes Do Raise Odds of T2DM Remission

TUESDAY, Dec. 18 (HealthDay News) -- For overweight adults, an intensive lifestyle intervention (ILI) is associated with a greater likelihood of remission compared with diabetes support and education (DSE), although the absolute remission rates are modest, according to a study published in the Dec. 19 issue of the Journal of the American Medical Association.

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Incidence of Specific Cancers Up for WTC Rescue Workers

TUESDAY, Dec. 18 (HealthDay News) -- For rescue/recovery workers at the World Trade Center (WTC), the incidence of prostate and thyroid cancers and multiple myeloma was increased for 2007 to 2008, according to a study published in the Dec. 19 issue of the Journal of the American Medical Association.

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Aspirin Use 10 Years Prior Tied to Incidence of Late AMD

TUESDAY, Dec. 18 (HealthDay News) -- For adults, regular use of aspirin 10 years prior to retinal examination is associated with increased incidence of late and neovascular age-related macular degeneration (AMD), according to a study published in the Dec. 19 issue of the Journal of the American Medical Association.

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For Whiplash, Usual Care, Single PT Session Found Adequate

TUESDAY, Dec. 18 (HealthDay News) -- For patients with acute whiplash, usual care in the emergency department and a single session with a physical therapist are recommended, according to a study published online Dec. 18 in The Lancet.

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Significant, Complex Link ID'd Between Sleepiness, Vitamin D

TUESDAY, Dec. 18 (HealthDay News) -- There is a significant correlation between 25-hydroxyvitamin D (25[OH]D) and sleepiness, which is affected by race for individuals with vitamin D deficiency (VitDd; defined as 25(OH)D <20 ng/mL), according to research published in the December issue of the Journal of Clinical Sleep Medicine.

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Suicide Risk Highest Shortly After Parental Psychiatric Event

TUESDAY, Dec. 18 (HealthDay News) -- Among adults and adolescents who have been hospitalized for an attempted suicide, the risk of suicide is highest within two years of a parental event (suicide attempt and suicide, inpatient care, and disability pension due to psychiatric diagnoses), especially among girls, according to a study published online Dec. 12 in PLOS ONE.

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Polygenic Risk Score Helpful for Women With Familial Breast CA

TUESDAY, Dec. 18 (HealthDay News) -- For women affected by familial breast cancer, a polygenic risk score based on 22 genomic variants can identify women at high-risk of breast cancer, according to a study published in the Dec. 10 issue of the Journal of Clinical Oncology.

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Life Expectancy Has Increased With Drop in Air Pollutants

TUESDAY, Dec. 18 (HealthDay News) -- Life expectancy has improved, particularly in urban and densely populated areas of the country, in response to reductions in ambient levels of fine particulate matter seen from 2000 to 2007, according to a study published in the January issue of Epidemiology.

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Workplace Bullying Linked to Psychotropic Medication Use

TUESDAY, Dec. 18 (HealthDay News) -- Experiencing or observing workplace bullying increases the risk of subsequent psychotropic medication use, according to a study published online Dec. 12 in BMJ Open.

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Length-of-Stay, Readmissions Down in VA Hospitals

TUESDAY, Dec. 18 (HealthDay News) -- Over a 14-year period (1997 to 2010), the risk-adjusted hospital length of stay (LOS) and hospital readmission rates decreased throughout Veterans Affairs hospitals, according to a study published in the Dec. 18 issue of the Annals of Internal Medicine.

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Aerobic Exercise Optimal for Reducing Fat Mass, Body Mass

TUESDAY, Dec. 18 (HealthDay News) -- For sedentary, overweight, or obese adults, aerobic training (AT) seems to be the optimal mode of exercise for reducing fat mass and body mass, while a combined approach of AT and resistance training (RT) increases the time commitment with no added loss compared with AT alone, according to a study published in the Dec. 15 issue of the Journal of Applied Physiology.

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Children With Mild TBI Exhibit White Matter Abnormalities

TUESDAY, Dec. 18 (HealthDay News) -- Children and adolescents who have experienced mild traumatic brain injury (concussion) show changes in brain white matter that persist months after the injury, even after symptoms have disappeared, according to a study published in the Dec. 12 issue of The Journal of Neuroscience.

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Adalimumab Relieves Hidradenitis Suppurativa

TUESDAY, Dec. 18 (HealthDay News) -- For patients with moderate-to-severe hidradenitis suppurativa (HS), a chronic skin disease characterized by painful abscesses, nodules, and draining fistulas in the axilla and groin, treatment with once-weekly adalimumab is associated with improvements in pain and inflammation, according to a study published online Dec. 17 in the Annals of Internal Medicine.

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STEMI Guidelines Emphasize Timely Reperfusion, Ideally PCI

MONDAY, Dec. 17 (HealthDay News) -- New guidelines urge timely management for patients with ST-segment elevation myocardial infarction (STEMI), according to a scientific report co-published online Dec. 17 in Circulation and the Journal of the American College of Cardiology.

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AAP Urges United Nations Not to Ban Thimerosal in Vaccines

MONDAY, Dec. 17 (HealthDay News) -- In response to the United Nations (UN) Environmental Program international treaty, which seeks to reduce mercury exposure from different sources, the American Academy of Pediatrics (AAP) has joined the World Health Organization (WHO) in urging the UN to reconsider their stance on thimerosal (ethyl mercury), a component used in multi-dose vaccine vials to prevent contamination. The AAP's statement of endorsement of the WHO's recommendation along with three related commentaries have been published online Dec. 17 in Pediatrics.

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Supplementation of Formula With LCPUFAs Ups Infant Visual Acuity

MONDAY, Dec. 17 (HealthDay News) -- For infants, supplementation of formula with long-chain polyunsaturated fatty acids (LCPUFAs) correlates with improved visual acuity in the first year of life, according to research published online Dec. 17 in Pediatrics.

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Vitamin D, Iron Balanced With 500 mL Milk/Day for Children

MONDAY, Dec. 17 (HealthDay News) -- Two cups of cow's milk per day is sufficient to maintain healthy vitamin D and iron stores for most young children, according to a study published online Dec. 17 in Pediatrics.

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Snack Foods Linked to Colorectal Cancer Risk in Lynch Syndrome

MONDAY, Dec. 17 (HealthDay News) -- People with Lynch syndrome have a higher risk of developing early colon cancer if they eat a diet heavy on snacks such as fried foods and sodas, according to a study published online Dec. 17 in Cancer.

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Dietary Fat Increases Glucose Level and Insulin Needs

MONDAY, Dec. 17 (HealthDay News) -- A high-fat meal increases the postprandial glucose levels and insulin requirements of patients with type 1 diabetes, according to research published online Nov. 27 in Diabetes Care.

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Health Care Satisfaction Rated As High by Unacculturated Hispanics

MONDAY, Dec. 17 (HealthDay News) -- Hispanic patients, particularly unacculturated Hispanics, rate their health care experience more highly than do other patient groups, according to a study published in the October issue of the Journal of Immigrant and Minority Health.

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Viewing CPR Video Tool Lowers CPR Use in Advanced Cancer

MONDAY, Dec. 17 (HealthDay News) -- Compared to patients with advanced cancer who were simply told about the likelihood of success with cardiopulmonary resuscitation (CPR), those who viewed a video of CPR were less likely to opt for its use, according to research published online Dec. 10 in the Journal of Clinical Oncology.

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Risk Factors ID'd for Revision of Total Hip Replacement

MONDAY, Dec. 17 (HealthDay News) -- Younger, taller, and heavier patients who undergo primary total hip replacement (THR) are at a greater risk of needing a revision surgery, according to research published in the December issue of Arthritis Care & Research.

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UV Nail Lamps Do Not Significantly Up Skin Cancer Risk

FRIDAY, Dec. 14 (HealthDay News) -- Ultraviolet (UV) nail lamps, used for professional and personal nail techniques, do not pose a clinically significant skin cancer risk, according to a letter to the editor published online Dec. 6 in the Journal of Investigative Dermatology.

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Tenofovir Effectively Treats Adolescents With Chronic HBV

FRIDAY, Dec. 14 (HealthDay News) -- In adolescents infected with hepatitis B virus (HBV), once-daily tenofovir treatment for 72 weeks effectively suppresses HBV DNA and normalizes alanine aminotransferase (ALT) values, regardless of prior HBV treatment exposure, according to research published in the December issue of Hepatology.

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Trunk Exercise Reduces Pain, Disability in Low Back Pain

FRIDAY, Dec. 14 (HealthDay News) -- For patients with chronic low back pain, compared with general exercise, specific trunk exercise results in significant reductions in self-rated disability and pain but similar changes in anticipatory postural adjustments, according to a study published in the Dec. 1 issue of Spine.

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Cardiac Rhythm Devices Mar Quality of Life for Children

FRIDAY, Dec. 14 (HealthDay News) -- The presence of cardiac rhythm devices negatively impacts pediatric patient and parent-reported quality of life (QOL), according to a study published online Dec. 4 in Circulation: Arrhythmia and Electrophysiology.

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Predictors of Organ Damage Identified in Patients With SLE

FRIDAY, Dec. 14 (HealthDay News) -- Patient age, hypertension, and corticosteroid use are the most important predictors of the cumulative organ damage that occurs in patients with systemic lupus erythematosus (SLE), according to research published in the December issue of Arthritis & Rheumatism.

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Leisure-Time Physical Activity Could Add Up to Five Years to Life

FRIDAY, Dec. 14 (HealthDay News) -- Leisure-time physical activity is associated with an increased life expectancy of up to 5.5 years, according to a study published online Dec. 11 in the American Journal of Preventive Medicine.

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For Elderly, Stroke Risk Up With Psychosocial Distress

FRIDAY, Dec. 14 (HealthDay News) -- In older black and white adults, psychosocial distress is related to fatal and nonfatal stroke, according to a study published online Dec. 13 in Stroke.

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Life Expectancy Up But More Healthy Years Lost to Disability

FRIDAY, Dec. 14 (HealthDay News) -- Although life expectancy is increasing, global estimates of healthy life expectancy indicate that the world's population loses more years of healthy life to disability today than in the past, according to the Global Burden of Disease Study 2010, published in the Dec. 15 special issue of The Lancet.

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Researchers Study Link Between Mind Wandering, Car Crashes

FRIDAY, Dec. 14 (HealthDay News) -- Mind wandering while driving correlates with an increased risk of responsibility for motor vehicle accidents, according to a study published online Dec. 13 in BMJ.

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Caffeinated Coffee May Reduce Oral/Pharyngeal Cancer Deaths

FRIDAY, Dec. 14 (HealthDay News) -- People who drink at least four cups of caffeinated coffee per day have about a 50 percent lower risk of death due to oral/pharyngeal cancer, according to a study published online Dec. 9 in the American Journal of Epidemiology.

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Exposure to Nature Improves Creative Thinking

THURSDAY, Dec. 13 (HealthDay News) -- Spending several days hiking without access to electronic devices improves scores on a creativity test by 50 percent, according to a study published online Dec. 12 in PLOS One.

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Dialysis-Requiring Acute Kidney Injuries on the Rise

THURSDAY, Dec. 13 (HealthDay News) -- From 2000 to 2009, the incidence of dialysis-requiring acute kidney injury (AKI) and resulting deaths increased considerably, according to research published online Dec. 6 in the Journal of the American Society of Nephrology.

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Exercise Performance Enhanced With Virtual Partner

THURSDAY, Dec. 13 (HealthDay News) -- Exercise duration is improved by exercising with a virtual partner, especially with a moderately superior partner, according to a study published in the October issue of the Annals of Behavioral Medicine.

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Adults With Autism Report Worse Health Care Experiences

THURSDAY, Dec. 13 (HealthDay News) -- Adults with autism report significantly worse health care experiences than adults without autism, according to a study published in the November issue of the Journal of General Internal Medicine.

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Immunogenicity Strongly Impacts Response to Adalimumab in RA

THURSDAY, Dec. 13 (HealthDay News) -- For patients with rheumatoid arthritis (RA), long-term clinical outcomes are good with etanercept and adalimumab; but for adalimumab, treatment response is strongly dependent on the presence or absence of anti-adalimumab antibodies, according to research published in the December issue of Arthritis & Rheumatism.

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Racial/Ethnic Differences ID'd in HTN Medication Behaviors

THURSDAY, Dec. 13 (HealthDay News) -- For adults with hypertension who are new users of antihypertensive medication, racial/ethnic differences in medication-taking behavior occur early in the course of treatment and may be mediated by health system factors, according to a study published online Dec. 10 in the Archives of Internal Medicine.

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Increased Risk of Diabetes for Breast Cancer Survivors

THURSDAY, Dec. 13 (HealthDay News) -- Postmenopausal women with breast cancer have an increased risk of developing diabetes, which varies over time, according to a study published online Dec. 12 in Diabetologia.

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Raising Taxes on Sugars, Fats May Be Viable Health Strategy

THURSDAY, Dec. 13 (HealthDay News) -- Taxes on sugar and saturated fats could be associated with beneficial dietary change, according to a study published online Dec. 11 in PLOS Medicine.

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Despite cART, Anal Cancer Risk Still High for HIV-Infected

THURSDAY, Dec. 13 (HealthDay News) -- For HIV-infected patients, despite combined antiretroviral treatment (cART), the risk of anal cancer is still much higher than in the general population, according to a study published in the Dec. 10 issue of the Journal of Clinical Oncology.

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Secondhand Smoke Ups Child Meningococcal Disease Risk

THURSDAY, Dec. 13 (HealthDay News) -- Exposure to secondhand smoke (SHS) correlates with an increased risk of invasive meningococcal disease in children, according to a study published online Dec. 10 in BMC Public Health.

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~40 Percent of Cancer Patients Receive Opioids at End of Life

THURSDAY, Dec. 13 (HealthDay News) -- For patients with one of five common cancers, 43.6 percent receive at least one prescription of opioids in the last three months of life, according to a study published in the Dec. 10 issue of the Journal of Clinical Oncology.

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FDA: Chantix May Raise Risk for Cardiovascular Events

THURSDAY, Dec. 13 (HealthDay News) -- People who take the smoking cessation drug Chantix may be at increased risk for major adverse cardiovascular events (MACE), according to a Dec. 12 Drug Safety Coummnication bulletin posted by the U.S. Food and Drug Administration.

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Admission for Syncope Ups Risk of Death, Cardio Events

WEDNESDAY, Dec. 12 (HealthDay News) -- Among patients without previous comorbidity admitted for syncope, there is a significant increased risk of all-cause mortality, stroke, and cardiovascular hospitalization, according to a study published online Dec. 12 in the Journal of the American College of Cardiology.

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Care Based on Intracranial Pressure Not Superior in TBI

WEDNESDAY, Dec. 12 (HealthDay News) -- For patients with severe traumatic brain injury (TBI) treated in the intensive care unit, treatment based on maintaining monitored intracranial pressure is not superior to care based on imaging and clinical examination, according to a study published online Dec. 12 in the New England Journal of Medicine.

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Current Health Costs Pushing Docs to Make Urgent Choices

WEDNESDAY, Dec. 12 (HealthDay News) -- The current growth in health care's share of the gross domestic product (GDP) and need to implement learning health systems is forcing physicians to make important choices, according to a perspective piece published online Dec. 12 in the New England Journal of Medicine.

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ACOG to HHS: Reconsider Age Limit on Plan B Access

WEDNESDAY, Dec. 12 (HealthDay News) -- Physicians from the American Congress of Obstetricians and Gynecologists (ACOG), together with other health organizations, are urging the U.S. Department of Health and Human Services (HHS) to reconsider the age limit for access to Plan B One-Step emergency contraception.

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MRI, PET, and CSF Biomarkers Up Prediction of Alzheimer's

WEDNESDAY, Dec. 12 (HealthDay News) -- Adding data from magnetic resonance imaging (MRI), fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET), and cerebrospinal fluid (CSF) biomarkers to routine clinical testing can improve the ability to predict conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD), according to research published online Dec. 11 in Radiology.

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Smoking Cessation Cuts Pain in Patients With Spine Disorders

WEDNESDAY, Dec. 12 (HealthDay News) -- For patients with painful spinal disorders, there is a strong, clinically significant association between smoking cessation and improved patient-reported pain scores, according to a study published in the Dec. 5 issue of The Journal of Bone & Joint Surgery.

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Any Amount of Smoking Ups Sudden Cardiac Death in Women

WEDNESDAY, Dec. 12 (HealthDay News) -- For women without coronary heart disease (CHD) at baseline, smoking, even in small quantities, is associated with a significantly increased risk of sudden cardiac death (SCD), according to research published online Dec. 11 in Circulation: Arrhythmia and Electrophysiology.

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Home-Delivered Meals Keep Seniors in Their Homes

WEDNESDAY, Dec. 12 (HealthDay News) -- States with greater investment in community-based service networks that supply home-delivered meals to seniors have fewer low-care nursing home residents, according to research published online Dec. 3 in Health Services Research.

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NSAIDs Exacerbate Exercise-Induced Small Intestinal Injury

WEDNESDAY, Dec. 12 (HealthDay News) -- Nonsteroidal anti-inflammatory drugs (NSAIDs) aggravate exercise-induced small intestinal injury in athletes, according to a study published in the December issue of Medicine & Science in Sports & Exercise.

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Higher Carotenoid Levels Tied to Lower Breast Cancer Risk

TUESDAY, Dec. 11 (HealthDay News) -- Higher circulating levels of carotenoids correlate with a reduced risk of breast cancer, according to research published online Dec. 6 in the Journal of the National Cancer Institute.

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Prevalence of Nonrefractive Visual Impairment Increasing

TUESDAY, Dec. 11 (HealthDay News) -- From 1999-2002 to 2005-2008, there has been an increase in the prevalence of nonrefractive visual impairment, which may be partly due to the increasing prevalence of diabetes, specifically long-duration diabetes, according to research published in the Dec. 12 issue of the Journal of American Medical Association.

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Adolescent ADHD Predictor of Problems in Adulthood

TUESDAY, Dec. 11 (HealthDay News) -- Attention-deficit/hyperactivity disorder (ADHD) in adolescence is a major predictor of physical, mental, work, and financial problems in adulthood, according to a study published online Dec. 10 in Pediatrics.

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Compression-Only CPR Best for Out-of-Hospital Cardiac Arrest

TUESDAY, Dec. 11 (HealthDay News) -- Among out-of-hospital cardiac arrest patients who receive shocks with public-access defibrillation, compression-only cardiopulmonary resuscitation (CPR) is more effective than conventional CPR, according to a study published online Dec. 10 in Circulation.

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Loneliness Linked to Increased Dementia Risk

TUESDAY, Dec. 11 (HealthDay News) -- Older adults who feel lonely have a higher risk of developing dementia, according to a study published online Dec. 10 in the Journal of Neurology, Neurosurgery & Psychiatry.

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NHANES Data Don't Support BPA, Chronic Disease Link

TUESDAY, Dec. 11 (HealthDay News) -- An analysis of data from a public health database has shown no association between urinary bisphenol A (BPA) levels and chronic diseases, unlike previous studies, but this dataset may be inappropriate to analyze such associations, according to research published online Dec. 5 in PLOS One.

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Benzodiazepines Linked to Higher Risk of Pneumonia

TUESDAY, Dec. 11 (HealthDay News) -- Benzodiazepine use is associated with an increased risk of developing pneumonia as well as increased mortality following pneumonia, according to a study published online Dec. 5 in Thorax.

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Mindfulness-Based Cognitive Therapy Beneficial in Diabetes

TUESDAY, Dec. 11 (HealthDay News) -- For patients with diabetes and low levels of emotional well-being, mindfulness-based cognitive therapy (MBCT) improves emotional distress and health-related quality of life, according to a study published online Nov. 27 in Diabetes Care.

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Readmission Seen in ~7 Percent of Elective Spine Surgeries

MONDAY, Dec. 10 (HealthDay News) -- About 7 to 8 percent of Medicare beneficiaries who undergo elective spine surgery for degenerative conditions are readmitted to the hospital within 30 days, according to a study published in the October issue of The Spine Journal.

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Number of Independent Physicians Continues to Decline

MONDAY, Dec. 10 (HealthDay News) -- Physician business models are transforming, with a sustained shift away from independent practice, according to report released by the consulting firm Accenture.

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Maternal BMI Negatively Linked to Child Cognition

MONDAY, Dec. 10 (HealthDay News) -- Maternal pre-pregnancy body mass index (BMI) is negatively associated with children's cognitive performance at ages 5 and 7, although the overall effect size is modest, according to research published online Dec. 10 in Pediatrics.

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USPSTF: Use Interventions to Avert Tobacco Use in Children

MONDAY, Dec. 10 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends that primary care physicians offer behavioral counseling and educational interventions to prevent tobacco use among children and adolescents. This Recommendation Statement is based on an evidence review of 19 trials published online Dec. 11 in the Annals of Internal Medicine.

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Child Readmission for Asthma Tied to Medical Home Quality

MONDAY, Dec. 10 (HealthDay News) -- For pediatric patients, the quality of the medical home correlates with readmission after acute asthma hospitalization; and most readmissions after hospitalization are likely not preventable, according to two studies published online Dec. 10 in Pediatrics.

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Iron May Curb Behavioral Issues for LBW Infants

MONDAY, Dec. 10 (HealthDay News) -- Early iron supplementation in low birth weight (LBW) infants is not associated with cognitive function at age 3.5 years, but correlates with a reduction in the prevalence of behavioral problems, according to a study published online Dec. 10 in Pediatrics.

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Primary Care Financially Viable Even With Educational Debt

MONDAY, Dec. 10 (HealthDay News) -- For medical school graduates with median levels of educational debt, a career in primary care is financially viable, according to a study published online Nov. 16 in Academic Medicine.

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Spinal Fusion Surgery Not Associated With Stroke

MONDAY, Dec. 10 (HealthDay News) -- Undergoing spinal fusion surgery does not affect the risk of stroke within the three years after surgery, according to a study published in the December issue of the European Spine Journal.

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Raised Risk of Ischemic Stroke in Women With A-Fib Explored

MONDAY, Dec. 10 (HealthDay News) -- Women with atrial fibrillation (AF) have a higher risk of ischemic stroke than men with AF, related in part to differences in the percent time in the therapeutic range (TTR) associated with warfarin anticoagulation control, according to research published in the Dec. 15 issue of The American Journal of Cardiology.

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Longer UTI Treatment Doesn't Reduce Recurrence Among Men

MONDAY, Dec. 10 (HealthDay News) -- For men with urinary tract infection (UTI), longer duration of antibiotic treatment does not reduce recurrence; and treatment of preoperative bacteriuria has no clinical benefit, according to two studies published online Dec. 3 in the Archives of Internal Medicine.

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EHR Algorithm Can Be Used to Detect, Classify Diabetes

MONDAY, Dec. 10 (HealthDay News) -- Data from electronic health records (EHRs) can be used to detect more cases of diabetes than claim codes alone and can be used to accurately distinguish between type 1 and type 2 diabetes, according to a study published online Nov. 27 in Diabetes Care.

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Gene-Environment Interaction Ups Risk of Preeclampsia

MONDAY, Dec. 10 (HealthDay News) -- A genetic variant, AGT2R, in mothers, fathers, and neonates is associated with a significantly increased risk of preeclampsia in mothers with a body mass index (BMI) of 25 kg/m² or more, according to a study published online Nov. 5 in Placenta.

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Neuroplasticity Reduced in Teens Born Prematurely

FRIDAY, Dec. 7 (HealthDay News) -- Adolescents who were born prematurely have reduced neuroplasticity, which may explain their motor, learning, and memory difficulties, according to a study published in the Nov. 14 issue of the Journal of Neuroscience.

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Concerns for Long-Term Safety of Antipsychotics in Over 40s

FRIDAY, Dec. 7 (HealthDay News) -- For patients over the age of 40 with psychosis, treatment with one of the four most commonly used atypical antipsychotic (AAP) drugs (aripiprazole, olanzapine, quetiapine, and risperidone) may lack effectiveness and is associated with a high incidence of side effects, according to a study published online Nov. 27 in the Journal of Clinical Psychiatry.

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No Evidence That Doping Enhances Athletic Performance

FRIDAY, Dec. 7 (HealthDay News) -- Although use of recombinant human erythropoietin (rHuEPO) is prohibited among athletes because it reportedly enhances performance, there is no scientific evidence that it does so, according to a study published online Dec. 6 in the British Journal of Clinical Pharmacology.

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Synergistic Risk of VTE for Women With PCOS Using the Pill

FRIDAY, Dec. 7 (HealthDay News) -- For women with polycystic ovary syndrome (PCOS), the risk of venous thromboembolism is increased for non-users of oral contraceptives, and further increased for users of combined oral contraceptives, according to a study published online Dec. 3 in CMAJ, the journal of the Canadian Medical Association.

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Study Confirms Benefit of Adjunct CBT in Med-Resistant Depression

FRIDAY, Dec. 7 (HealthDay News) -- Cognitive behavioral therapy (CBT) is effective for reducing depressive symptoms when used as an adjunct to usual care in medication-resistant patients, according to a study published online Dec. 7 in The Lancet.

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Risk of Asthma Up for Children Born After Fertility Treatment

FRIDAY, Dec. 7 (HealthDay News) -- Children born to subfertile parents are more likely to have asthma, with the likelihood further increased for children born after the use of assisted reproduction technologies (ARTs), according to a study published online Dec. 5 in Human Reproduction.

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Health Care Law Boosts Savings on Meds for Medicare Recipients

FRIDAY, Dec. 7 (HealthDay News) -- Savings on prescription drugs related to the Affordable Care Act have reached $5.1 billion, according to a Dec. 3 news release from the U.S. Department of Health and Human Services.

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Anticompetitive Market Power Common in Managed Care Plans

FRIDAY, Dec. 7 (HealthDay News) -- For each of the three most popular types of managed care plans in the United States (point-of-service plan [POS], health maintenance organization [HMO], and preferred provider organization [PPO]), anticompetitive market power is widespread, according to a Nov. 28 news release from the American Medical Association (AMA).

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Emerging Risk Factors ID'd for Postpartum Depression

THURSDAY, Dec. 6 (HealthDay News) -- Emerging risk factors for postpartum depression include the serotonin transporter (5-HTT) genotype and omega-3 polyunsaturated fatty acid (n-3 PUFA) status, both of which may interact to affect risk, according to a review published in the November issue of The Canadian Journal of Psychiatry.

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Shift Length Affects Nurse Well-Being, Patient Satisfaction

THURSDAY, Dec. 6 (HealthDay News) -- For nurses, working extended hours is associated with increased job dissatisfaction and burnout, and with patient dissatisfaction, according to a study published in the November issue of Health Affairs.

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Low Testosterone Levels Affect Total Lipid Oxidation

THURSDAY, Dec. 6 (HealthDay News) -- Very low testosterone levels impact total lipid oxidation but have no effect on the production of very-low-density lipoprotein-triglycerides (VLDL-TGs), according to a study published online Nov. 27 in Diabetes.

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Socioeconomic Status Affects Cancer Trial Referrals

THURSDAY, Dec. 6 (HealthDay News) -- Patients of lower socioeconomic status are less likely to be referred to participate in early-phase cancer trials compared with patients of higher socioeconomic status, according to research published online Dec. 3 in the Journal of Clinical Oncology.

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Wealth Affects Link Between Psychological Stress, Mortality

THURSDAY, Dec. 6 (HealthDay News) -- Low socioeconomic status (SES) amplifies the association between psychological distress and all-cause mortality, according to a study published online Dec. 3 in the Archives of Internal Medicine.

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Impact of HTN Meds on Cardio Risk Affected by Body Size

THURSDAY, Dec. 6 (HealthDay News) -- For patients with hypertension, the impact of the type of treatment on cardiovascular risk is affected by body size, according to a study published online Dec. 6 in The Lancet.

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Reports Raise Concerns About Antiseptic Product Contamination

THURSDAY, Dec. 6 (HealthDay News) -- Recent reports linking outbreaks of infection to antiseptic products have prompted the U.S. Food and Drug Administration to evaluate the need for sterile manufacture of such products, according to a perspective piece published in the Dec. 6 issue of the New England Journal of Medicine.

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Health Inequalities Persist Despite Rising Prosperity in U.K.

THURSDAY, Dec. 6 (HealthDay News) -- In the decade from 1998 to 2007, life expectancy in England increased with increasing prosperity; however, more deprived areas had smaller improvements in life expectancy, resulting in widening health disparities, according to a study published online Dec. 4 in BMJ.

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FDA: Public-Private Venture Set to Improve Regulatory Science

THURSDAY, Dec. 6 (HealthDay News) -- The Medical Device Innovation Consortium (MDIC), the first public-private partnership to promote medical device regulatory science, has been established, according to a Dec. 3 news release issued by the U.S. Food and Drug Administration.

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Microarray Analysis May Add to Karyotyping for Prenatal Testing

WEDNESDAY, Dec. 5 (HealthDay News) -- Microarray analysis can be a useful addition to karyotyping in prenatal testing and appears to be helpful in the investigation of stillbirth, according to two studies published in the Dec. 6 issue of the New England Journal of Medicine.

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FDA: Zofran 32-mg Dose Pulled From Market

WEDNESDAY, Dec. 5 (HealthDay News) -- The 32-mg, single intravenous dose of Zofran (ondansetron), an anti-nausea drug, is being removed from the market due to its potential to cause serious, even fatal, cardiac damage, according to a Drug Safety Communication (DSC) issued Dec. 4 by the U.S. Food and Drug Administration.

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FDA Requests Removal of Generic Budeprion XL 300 mg

WEDNESDAY, Dec. 5 (HealthDay News) -- The U.S. Food and Drug Administration has concluded that generic Budeprion XL 300 mg (extended-release bupropion hydrochloride, manufactured by Impax Laboratories and distributed by Teva Pharmaceuticals) cannot be considered therapeutically equivalent to the brand-name product, according to a perspective piece published online Dec. 5 in the New England Journal of Medicine.

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Fungus Was Deadly Infection Source Following Tornado

WEDNESDAY, Dec. 5 (HealthDay News) -- Following the 2011 Joplin, Mo., tornado, a cluster of cutaneous mucormycosis fungal infections was observed, which correlated with substantial morbidity and mortality, according to research published in the Dec. 6 issue of the New England Journal of Medicine.

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Extended Sleep Time Linked to Reduced Pain Sensitivity

WEDNESDAY, Dec. 5 (HealthDay News) -- Extending bedtime for sleepy healthy adults reduces daytime sleepiness and correlates with reduced pain sensitivity, according to a study published in the Dec. 1 issue of SLEEP.

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Stimulant Still Available for Sale Despite FDA Action

WEDNESDAY, Dec. 5 (HealthDay News) -- Products containing 1,3-dimethylamylamine (DMAA), a stimulant marketed as a dietary supplement in the United States, are still available for sale despite a warning from the U.S. Food and Drug Administration, according to a research letter published online Dec. 3 in the Archives of Internal Medicine.

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SAMHSA: Prevalence of Mental Illness in U.S. Stable in 2011

WEDNESDAY, Dec. 5 (HealthDay News) -- In 2011, nearly one in five adults in the United States reported any mental illness (AMI), and one in twenty suffered from serious mental illness (SMI), according to a Nov. 29 report published by the Substance Abuse and Mental Health Services Administration (SAMHSA).

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Breath Test Shows Potential for Detecting Colorectal Cancer

WEDNESDAY, Dec. 5 (HealthDay News) -- Analysis of volatile organic compounds (VOCs) from breath samples is able to distinguish healthy patients from those with colorectal cancer with more than 75 percent accuracy, according to a study published in the January issue of the British Journal of Surgery.

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Tetanus-Diphtheria-Pertussis Shot Deemed Safe for Seniors

WEDNESDAY, Dec. 5 (HealthDay News) -- Immunizing older adults with the tetanus-diphtheria-acellular pertussis (Tdap) vaccine appears to be safe, according to a study published online Nov. 28 in Clinical Infectious Diseases.

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Resistance Exercise Offers More Prolonged Glycemic Control

WEDNESDAY, Dec. 5 (HealthDay News) -- For patients with type 1 diabetes, resistance exercise is associated with a smaller initial decline in blood glucose compared with aerobic exercise, but offers a more prolonged reduction in post-exercise glycemia, according to research published online Nov. 19 in Diabetes Care.

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Periodontal Disease, Erectile Dysfunction Linked

TUESDAY, Dec. 4 (HealthDay News) -- For males aged 30 to 40 years, there is an association between chronic periodontitis (CP) and erectile dysfunction (ED), according to a study published online Dec. 4 in The Journal of Sexual Medicine.

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Five-Hour Protected Sleep Feasible for Medical Interns

TUESDAY, Dec. 4 (HealthDay News) -- Implementation of a five-hour period of protected sleep is feasible for medical interns on long shifts, resulting in interns getting more uninterrupted sleep and feeling more alert the next day, according to a study published in the Dec. 5 issue of the Journal of the American Medical Association.

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Few Internal Medicine Residents Choosing Primary Care

TUESDAY, Dec. 4 (HealthDay News) -- Only about one in five graduating internal medicine residents in the United States plan to enter general internal medicine (GIM), which is more common among graduates of primary care programs, women, and U.S. medical graduates, according to a study published in the Dec. 5 issue of the Journal of the American Medical Association.

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Predictors of QoL ID'd for Long-Term Lymphoma Survivors

TUESDAY, Dec. 4 (HealthDay News) -- A considerable proportion of long-term survivors of non-Hodgkin's lymphoma (NHL) have persistently low or worsening quality of life (QoL), which is predicted by age, comorbidity, and the perception of cancer's impact, according to research published online Dec. 3 in the Journal of Clinical Oncology.

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Psychotropics Seem to Be Appropriately Prescribed to Teens

TUESDAY, Dec. 4 (HealthDay News) -- There is no evidence that psychotropic medications are being overly prescribed or misused by U.S. adolescents, according to a study published online Dec. 3 in the Archives of Pediatrics & Adolescent Medicine.

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SAMHSA: >11,000 ER Visits for Synthetic Marijuana in 2010

TUESDAY, Dec. 4 (HealthDay News) -- In 2010, more than 11,000 emergency department visits involved a synthetic cannabinoid product (synthetic marijuana, commonly known by street names including "Spice" and "K2"), 75 percent of which were among those aged 12 to 29 years, according to a report published Dec. 4 by the Substance Abuse and Mental Health Services Administration (SAMHSA).

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CDC: Flu Season Has Started and Hitting Hard

TUESDAY, Dec. 4 (HealthDay News) -- Flu season descended on the United States early and hard this year, with significant increases in flu activity observed in just the past two weeks, according to a Nov. 30 weekly surveillance report published by the U.S. Centers for Disease Control and Prevention.

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Smoking, Depression Tied to Lower Bone Accrual in Teen Girls

TUESDAY, Dec. 4 (HealthDay News) -- Depression and smoking appear to have a negative impact on bone accrual in adolescent girls, according to a study published online Dec. 4 in the Journal of Adolescent Health.

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Standardized Blood Culture Process Reduces Contamination

TUESDAY, Dec. 4 (HealthDay News) -- Introduction of a standardized sterile collection process for blood cultures can reduce peripheral blood culture contamination rates and hospital charges, according to research published online Dec. 3 in Pediatrics.

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Lower BMI, Especially in Boys, Has Protective Effect in Acne

TUESDAY, Dec. 4 (HealthDay News) -- Family history, body mass index, and diet are all linked to the risk of moderate-to-severe acne in young adults, according to a study published in the December issue of the Journal of the American Academy of Dermatology.

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High Fructose Corn Syrup Availability Linked to Diabetes

MONDAY, Dec. 3 (HealthDay News) -- Countries with a higher availability of high fructose corn syrup (HFCS) have a higher prevalence of type 2 diabetes, according to a study published online Nov. 27 in Global Public Health.

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Use of Upper Endoscopy Should Be Limited in GERD

MONDAY, Dec. 3 (HealthDay News) -- For patients with gastroesophageal reflux disease (GERD), use of upper endoscopy should be considered only in specific clinical situations, according to best practice advice issued by the American College of Physicians and published in the Dec. 4 issue of the Annals of Internal Medicine.

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Final Diagnostic Criteria for DSM-5 Approved by APA

MONDAY, Dec. 3 (HealthDay News) -- The final diagnostic criteria for the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) have been approved by the American Psychiatric Association (APA) Board of Trustees.

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United States at Tipping Point in Helping Smokers Quit

MONDAY, Dec. 3 (HealthDay News) -- The United States stands poised on the brink of implementing health insurance coverage requirements that will help smokers quit, but the federal government and many states now offer too little help, according to a report issued Dec. 3 by the American Lung Association.

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Post-Injury Blood Alcohol Inversely Tied to Mortality

MONDAY, Dec. 3 (HealthDay News) -- For patients with traumatic injuries, there is an inverse dose-response association between blood alcohol concentration and in-hospital mortality, according to a study published in the December issue of Alcohol.

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Recent Increase in Adverse TMP-SMX Reactions in Children

MONDAY, Dec. 3 (HealthDay News) -- There has been a significant increase in adverse drug reactions (ADRs) associated with use of trimethoprim-sulfamethoxazole (TMP-SMX) for treatment of skin and soft tissue infection (SSTI) in children, according to research published online Dec. 3 in Pediatrics.

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Epidural Steroid Shot Has Adverse Effect on Bone Density

MONDAY, Dec. 3 (HealthDay News) -- For postmenopausal women, treatment of the pain associated with radiculopathy with epidural steroid injection (ESI) has an adverse effect on bone mineral density (BMD), according to a study published in the Dec. 1 issue of Spine.

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Increasing Number of Workers in Self-Insured Health Plans

MONDAY, Dec. 3 (HealthDay News) -- There has been a recent increase in the percentage of workers in the private sector who are enrolled in self-insured health plans, in which the employer assumes the financial risk related to health insurance (unlike a fully-insured plan, where the insurance company assumes the risk), according to research published in the November issue of the Employee Benefit Research Institute's Notes.

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ART Cuts HIV Infection in Serodiscordant Couples in China

MONDAY, Dec. 3 (HealthDay News) -- For uninfected partners of HIV-positive individuals in China, transmission is reduced with antiretroviral therapy for the HIV-positive individual, according to a study published online Dec. 1 in The Lancet.

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Children Undergoing More Diagnostic Imaging Procedures

MONDAY, Dec. 3 (HealthDay News) -- Children are undergoing more diagnostic imaging procedures (DIPs), with higher-radiation DIPs accounting for an increasing proportion, according to a study published online Dec. 3 in Pediatrics.

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Improved Survival Seen in Ovarian CA With Metformin Use

MONDAY, Dec. 3 (HealthDay News) -- For women with ovarian cancer, metformin use is associated with significantly improved survival, according to a study published online Dec. 3 in Cancer.

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