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September 2012 Briefing - Family Practice

Here are what the editors at HealthDay consider to be the most important developments in Family Practice for September 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Standards for Diabetes Education, Support Updated

FRIDAY, Sept. 28 (HealthDay News) -- A task force from the American Association of Diabetes Educators and the American Diabetes Association has updated the national standards for diabetes self-management education and support, according to a report published online Sept. 20 in Diabetes Care.

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History of Sexual Abuse Slows Response to Bariatric Surgery

FRIDAY, Sept. 28 (HealthDay News) -- Although studies suggest that individuals with a history of sexual abuse may experience less weight loss soon after bariatric surgery, most individuals still benefit from the surgical procedure, with increased weight loss seen over time, according to research published in the October issue of Obesity Reviews.

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Pain Intensity in Juvenile Arthritis Varies Widely

FRIDAY, Sept. 28 (HealthDay News) -- In youth with juvenile idiopathic arthritis (JIA), pain intensity varies within days, impacting patient quality of life, according to a study published online Sept. 12 in Arthritis Care & Research.

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SNPs Linked to Erectile Dysfunction After Radiotherapy

FRIDAY, Sept. 28 (HealthDay News) -- Twelve single nucleotide polymorphisms (SNPs) are associated with development of erectile dysfunction (ED) following radiotherapy for prostate cancer, according to a study published online Sept. 28 in the International Journal of Radiation Oncology*Biology*Physics.

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Review Finds Little Impact of Exercise Interventions on Kids

FRIDAY, Sept. 28 (HealthDay News) -- Interventions to increase physical activity in children and adolescents have little impact, according to research published online Sept. 27 in BMJ.

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Benzodiazepine Use Linked to Increased Risk of Dementia

FRIDAY, Sept. 28 (HealthDay News) -- New use of benzodiazepines correlates with an increase in the risk of dementia, according to a study published online Sept. 27 in BMJ.

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Single Progesterone Test Can Rule Out Viable Pregnancy

FRIDAY, Sept. 28 (HealthDay News) -- For women in early pregnancy with symptoms and an inconclusive ultrasound assessment, a single progesterone measurement can rule out a viable pregnancy, according to a study published online Sept. 27 in BMJ.

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Many Support Financial Incentives for Organ Donation

FRIDAY, Sept. 28 (HealthDay News) -- At least 40 percent of Canadians consider it acceptable to offer financial incentives to encourage kidney donation, according to a study published online Sept. 27 in the Clinical Journal of the American Society of Nephrology.

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Simple Form Identifies Ovarian Cancer Warning Signs

FRIDAY, Sept. 28 (HealthDay News) -- A simple, quick, easy-to-use paper form can help identify symptoms potentially indicative of ovarian cancer in women treated in the primary care clinic setting, according to research published in the September issue of the Open Journal of Obstetrics and Gynecology.

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Pediatric Kidney Disease Tied to Abnormal Carotid Arteries

THURSDAY, Sept. 27 (HealthDay News) -- Ultrasound measurements of carotid intima-media thickness (cIMT) are significantly elevated among children with chronic kidney disease (CKD) compared with healthy controls, according to a study published online Sept. 13 in the Clinical Journal of the American Society of Nephrology.

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Study Supports Diet High in Total Antioxidants for Lower MI Risk

THURSDAY, Sept. 27 (HealthDay News) -- A diet high in total antioxidant capacity, based on fruits, vegetables, coffee, and whole grains, is associated with a lower risk of myocardial infarction, according to a study published in the October issue of The American Journal of Medicine.

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Much of Intellectual Disability Not Genetically Inherited

THURSDAY, Sept. 27 (HealthDay News) -- A considerable proportion of severe intellectual disability results from de-novo genetic variants, suggesting that only a small proportion of cases are likely to be inherited in an autosomal recessive fashion, according to a study published online Sept. 27 in The Lancet.

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Topical NSAIDs Effective for Chronic Musculoskeletal Pain

THURSDAY, Sept. 27 (HealthDay News) -- Topical nonsteroidal anti-inflammatory drugs (NSAIDs) can provide effective pain relief for chronic musculoskeletal pain in adults, according to a review published online Sept. 12 in The Cochrane Library.

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Infant Regulatory Problems Predict Somatic Symptoms

THURSDAY, Sept. 27 (HealthDay News) -- Functional somatic symptoms (FSS) in childhood may be predicted by feeding, sleeping, or tactile reactivity problems in the first 10 months of life, according to a study published online Sept. 27 in The Journal of Pediatrics.

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Negative Response to Uncertain Prenatal Microarray Results

THURSDAY, Sept. 27 (HealthDay News) -- Women do not necessarily consider the potential significance and ambiguity of the information they could receive from prenatal microarray testing, according to a study published online Sept. 6 in Genetics in Medicine.

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Insulin Sensitivity Lower in Adults Born Preterm

THURSDAY, Sept. 27 (HealthDay News) -- Middle-aged adults who were born preterm, even moderately preterm (32 to 36 weeks' gestation), are less insulin sensitive compared with adults who were born at term, according to research published in the October issue of Diabetes.

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Complementary Medicine Superior to Usual PTSD Therapy

THURSDAY, Sept. 27 (HealthDay News) -- A complementary medicine intervention of healing touch with guided imagery (HT+GI) reduces post-traumatic stress disorder (PTSD) and related symptoms in returning combat-exposed active duty military personnel, according to a study published in the September issue of Military Medicine.

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Choice of Psoriasis Treatment Affects CVD Event Rates

THURSDAY, Sept. 27 (HealthDay News) -- Compared with other anti-psoriatic therapies, systemic anti-inflammatory treatment of patients with severe psoriasis with biologic agents or methotrexate is associated with a lower combined risk of death, myocardial infarction, and stroke, according to research published online Sept. 11 in the Journal of Internal Medicine.

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Being Deemed 'Unfit to Drive' Cuts Subsequent Road Crashes

WEDNESDAY, Sept. 26 (HealthDay News) -- Medical warnings to patients who are potentially unfit to drive correlate with a reduction in the number of road crashes in which the patient is a driver, according to a study published in the Sept. 27 issue of the New England Journal of Medicine.

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Trio of Studies Look at Impact of Sugary Drinks on Weight

FRIDAY, Sept. 21 (HealthDay News) -- For adults, children, and teens, drinking sugar-sweetened beverages correlates with increases in body mass index (BMI) and obesity, according to three studies published online Sept. 21 in the New England Journal of Medicine to coincide with presentation at the annual meeting of The Obesity Society, held from Sept. 20 to 24 in San Antonio, Texas.

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Effect of BMI Category on CVD Risk Quantified in Children

WEDNESDAY, Sept. 26 (HealthDay News) -- For school-aged children, cardiovascular disease risk parameters are worse for those who are overweight, and substantially worse for those who are obese, compared with their normal-weight peers, according to a review published online Sept. 25 in BMJ.

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Physicians' Gut Feelings Should Not Be Dismissed

WEDNESDAY, Sept. 26 (HealthDay News) -- Having a gut feeling about the seriousness of an illness, despite clinical assessment of non-severe illness, is associated with an increased risk of serious illness, according to a study published online Sept. 25 in BMJ.

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Drugs Similar in Efficacy for Neuropathic Pain in Diabetes

WEDNESDAY, Sept. 26 (HealthDay News) -- In the treatment of patients with chronic diabetic peripheral neuropathic pain (DPNP), there are no significant differences in pain-relief efficacy between amitriptyline, duloxetine, and pregabalin; however, pregabalin improves sleep continuity and duloxetine improves daytime functioning, according to research published online Sept. 18 in Diabetes Care.

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Efficacy of Black Cohosh for Menopausal Symptoms Unclear

WEDNESDAY, Sept. 26 (HealthDay News) -- There is insufficient evidence to support the use of black cohosh for menopausal symptoms, according to the results of a systematic literature review published online Sept. 12 in The Cochrane Library.

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Antibiotic Use Varies by Season, Geographic Region for Elderly

WEDNESDAY, Sept. 26 (HealthDay News) -- Antibiotic usage among older adults varies widely by geographical region and season, according to a study published online Sept. 24 in the Archives of Internal Medicine.

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Energy Expenditure Up With Active Video Gaming

WEDNESDAY, Sept. 26 (HealthDay News) -- Compared with traditional sedentary video game playing, active video game playing (e.g., using the Xbox 360) significantly increases heart rate, oxygen uptake, and energy expenditure, according to research published online Sept. 24 in the Archives of Pediatrics & Adolescent Medicine.

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Risk of Post-Cesarean Infection Up for Overweight, Obese

WEDNESDAY, Sept. 26 (HealthDay News) -- About 10 percent of U.K. women who undergo cesarean section develop a surgical site infection, with the odds significantly increased for overweight or obese women, according to a study published in the October issue of BJOG: An International Journal of Obstetrics and Gynaecology.

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Early Menopause Ups Coronary Heart Disease and Stroke Risk

WEDNESDAY, Sept. 26 (HealthDay News) -- Women who experience menopause before the age of 46 have an increased risk of coronary heart disease and stroke, according to a study published in the October issue of Menopause.

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Medicare Knee Replacement Numbers Up Over Last 20 Years

TUESDAY, Sept. 25 (HealthDay News) -- From 1991 to 2010 there was a 161.5 percent annual volume increase in primary total knee arthroplasty (TKA) among Medicare enrollees as well as an increase in per capita utilization, according to research published in the Sept. 26 issue of the Journal of the American Medical Association.

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Marijuana-Like Chemical Corrects Behavior in Fragile X

TUESDAY, Sept. 25 (HealthDay News) -- The protein lost in fragile X syndrome, the most common genetic cause of autism, is part of a complex that, when targeted by a drug that boosts a natural marijuana-like chemical in the brain, corrects some of the behavioral abnormalities in mice, according to a study published online Sept. 25 in Nature Communications.

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Guidelines Issued for Improving Outcomes for ICD Recipients

TUESDAY, Sept. 25 (HealthDay News) -- Patient and family education and psychological support are key components for improving outcomes for implantable cardioverter defibrillator (ICD) recipients, according to a scientific statement issued by the American Heart Association and published online Sept. 24 in Circulation.

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Sporadic Jakob-Creutzfeldt Disease Often Misdiagnosed

TUESDAY, Sept. 25 (HealthDay News) -- Patients with sporadic Jakob-Creutzfeldt disease (sCJD) are often misdiagnosed, with only 18 percent correctly diagnosed at their first assessment, according to a study published online Sept. 24 in the Archives of Neurology.

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Stress-Weight Link in Black and White Teen Girls Studied

TUESDAY, Sept. 25 (HealthDay News) -- Increased stress is tied to weight gain in teenage girls, particularly black girls, according to a study published online Sept. 20 in the Annals of Behavioral Medicine.

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Bacteriophages of P. acnes Have Limited Genetic Diversity

TUESDAY, Sept. 25 (HealthDay News) -- Bacteriophages that infect the dominant bacteria inhabitant of the human sebaceous follicle, Propionibacterium acnes (P. acnes), which contributes to the pathogenesis of acne, have limited genetic diversity and display a broad host range, according to a study published online Sept. 25 in mBio.

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Obstructive Sleep Apnea Linked to Perinatal Complications

TUESDAY, Sept. 25 (HealthDay News) -- Obstructive sleep apnea (OSA) is associated with perinatal complications in obese pregnant women, according to a study published online Sept. 21 in Obstetrics & Gynecology.

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Study Examines Prevalence of Local Allergic Rhinitis

TUESDAY, Sept. 25 (HealthDay News) -- Local allergic rhinitis (LAR) is prevalent among patients with rhinitis, affecting about one in four, and is often associated with childhood onset and persistent, severe conjunctivitis and/or asthma, according to a study published in the October issue of Allergy.

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Interrelated Anxiety, GI, and Sensory Issues Common in ASD

TUESDAY, Sept. 25 (HealthDay News) -- For children with autism spectrum disorder (ASD), a possibly interrelated phenomenon of co-existing anxiety, sensory over-responsivity, and gastrointestinal (GI) problems is common, according to a study published online Aug. 1 in the Journal of Abnormal Child Psychology.

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Being Born Preterm Linked to Later Pregnancy Complications

MONDAY, Sept. 24 (HealthDay News) -- Women born preterm are at significantly increased risk of experiencing pregnancy complications of their own, according to a study published online Sept. 24 in CMAJ, the journal of the Canadian Medical Association.

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Leadership Inversely Associated With Stress Levels

MONDAY, Sept. 24 (HealthDay News) -- Leaders have lower levels of cortisol and lower reports of anxiety, with a dose-response association seen for levels of leadership, which seems to be mediated by a sense of control, according to a study published online Sept. 24 in the Proceedings of the National Academy of Sciences.

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Surveillance for Low-Risk Prostate Cancer Examined

MONDAY, Sept. 24 (HealthDay News) -- For men with low-risk prostate cancer, projections show that active surveillance may result in a modest decline in prostate cancer-specific survival, but allows men to remain treatment-free for several more years compared with immediate radical prostatectomy, according to a study published online Sept. 24 in Clinical Cancer Research.

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Pediatricians Should Provide Support for Adoptive Families

MONDAY, Sept. 24 (HealthDay News) -- As more children are adopted each year, pediatricians must be knowledgeable about adoption issues and model positive language for adoptive families, according to a clinical report published online Sept. 24 in Pediatrics.

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Effect of Behavioral Intervention on Alcohol Misuse Evaluated

MONDAY, Sept. 24 (HealthDay News) -- Behavioral counseling interventions may be beneficial for adults with risky drinking behaviors, according to a review and meta-analysis published online Sept. 25 in the Annals of Internal Medicine.

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Genetic Variants Identified for Risk of Male Breast Cancer

MONDAY, Sept. 24 (HealthDay News) -- Two single nucleotide polymorphisms (SNPs) associated with an increased risk of male breast cancer have been identified, according to a study published online Sept. 23 in Nature Genetics.

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Taste Perceptions Differ for Obese, Non-Obese Children

MONDAY, Sept. 24 (HealthDay News) -- Obese children are less able than their normal-weight peers to identify taste qualities, according to a study published online Sept. 20 in the Archives of Disease in Childhood.

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Deaths Due to Poisoning, Suicide, Falls Up in Last Decade

MONDAY, Sept. 24 (HealthDay News) -- Deaths due to suicide, falls, and unintentional poisoning increased over the last decade, while motor vehicle accident deaths declined by 25 percent, according to research published online Sept. 20 in the American Journal of Public Health.

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AAP Strongly Discourages Home Trampolines

MONDAY, Sept. 24 (HealthDay News) -- Home trampoline use is strongly discouraged by the American Academy of Pediatrics (AAP), according to a policy statement published online Sept. 24 in Pediatrics.

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Childhood Antibiotic Exposure Linked to Development of IBD

MONDAY, Sept. 24 (HealthDay News) -- Early exposure to antianaerobic antibiotics in childhood is associated with an increased risk of developing inflammatory bowel disease (IBD), according to research published online Sept. 24 in Pediatrics.

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Limited Evidence on Medication Use for Youth With Autism

MONDAY, Sept. 24 (HealthDay News) -- There is a lack of evidence supporting the use of medications in adolescents and young adults with autism spectrum disorders (ASDs), according to a review published online Sept. 24 in Pediatrics.

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Safe for Intravenous Catheters to Be Replaced As Needed

FRIDAY, Sept. 21 (HealthDay News) -- Replacement of peripheral intravenous catheters as clinically indicated is as safe as routine replacement, according to a study published in the Sept. 22 issue of The Lancet, a theme issue on surgery.

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Central Centrifugal Cicatricial Alopecia Pathogenesis Studied

FRIDAY, Sept. 21 (HealthDay News) -- Protease-activated receptor 2 (PAR-2), which is activated by cowhage, may play a role in central centrifugal cicatricial alopecia (CCCA), the most common cause of scarring hair loss in African-American women, according to research published online Sept. 17 in the British Journal of Dermatology.

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Fewer Older People on the Street May Lead Youth to Riskier Lives

FRIDAY, Sept. 21 (HealthDay News) -- There is a difference in the age profile of people observed on the streets in affluent and deprived neighborhoods, which is not always reflective of the actual age profile of the community and may influence life-history strategies, according to a study published in the September issue of Human Nature.

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Skin Cancer Incidence Up After Pancreas Transplantation

FRIDAY, Sept. 21 (HealthDay News) -- Nonmelanoma skin cancers (NMSCs) commonly occur after pancreas transplantation (PT), particularly in those who have a history of skin cancer, according to a study published in the October issue of the Journal of the American Academy of Dermatology.

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Urge to Overeat Linked to Production of Natural Narcotic

FRIDAY, Sept. 21 (HealthDay News) -- When presented with tasty foods, the brain produces the opioid peptide enkephalin that stimulates an unexpected reward center in the brain and leads to overeating, according to a study published online Sept. 20 in Current Biology.

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Increased Prevalence of Obesity in Rural Areas

FRIDAY, Sept. 21 (HealthDay News) -- Rates of obesity are significantly higher among rural adults compared with urban residents, according to a study published in The Journal of Rural Health.

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Perceived Stress Linked to Asthma, Atopic Disorders

FRIDAY, Sept. 21 (HealthDay News) -- Perceived stress correlates with an increased risk of adult-onset asthma, allergic rhinitis, and atopic dermatitis as well as asthma medication use, according to a study published online Sept. 3 in Allergy.

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Health Benefits Seen for Moving to Less Poor Neighborhood

THURSDAY, Sept. 20 (HealthDay News) -- Moving from a high-poverty to a lower-poverty neighborhood correlates with long-term improvements in physical and mental health and subjective well-being, according to a study published in the Sept. 21 issue of Science.

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Channel Blockers Reduce Causes of Asthma Symptoms

THURSDAY, Sept. 20 (HealthDay News) -- Epithelial expression of the calcium-activated chloride channel (CaCC) TMEM16A is increased in patients with asthma, and its inhibition negatively regulates epithelial mucin secretion and airway smooth muscle contraction, according to a study published online Sept. 17 in the Proceedings of the National Academy of Sciences.

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Stress-Reducing Effect of Acute Exercise Persists

THURSDAY, Sept. 20 (HealthDay News) -- The anxiety-lowering effect of exercise seems to persist even after exposure to emotional stimuli, according to a study published online Aug. 14 in Medicine & Science in Sports & Exercise.

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Drug Improves Social Function in Fragile X Syndrome

THURSDAY, Sept. 20 (HealthDay News) -- A γ-aminobutyric acid type B (GABAB) agonist, STX209 (Arbaclofen), can significantly improve social function in patients with fragile X syndrome, according to a study published in the Sept. 19 issue of Science Translational Medicine.

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Thin Placenta at Birth Ups Risk of Sudden Cardiac Death Later

THURSDAY, Sept. 20 (HealthDay News) -- Sudden cardiac death in adults is associated with placental size at birth, with a significantly increased risk of death for decreased placental thickness, according to a study published online Sept. 19 in the International Journal of Epidemiology.

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Sequential Oral, Topical Tacrolimus Benefits Dermatitis

THURSDAY, Sept. 20 (HealthDay News) -- Sequential therapy with oral tacrolimus and topical tacrolimus may be an effective treatment for severe atopic dermatitis (AD), according to a pilot study published in the October issue of the Journal of the American Academy of Dermatology.

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Parent-Reported Child Food Allergies Often Unsubstantiated

THURSDAY, Sept. 20 (HealthDay News) -- Nearly one-third of parent-reported food allergies are not formally diagnosed by a physician, according to a study published online Sept. 3 in the Journal of Allergy and Clinical Immunology.

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Duration of Antiplatelet Drugs for Drug-Eluting Stents Studied

THURSDAY, Sept. 20 (HealthDay News) -- In patients receiving drug-eluting stents, dual antiplatelet therapy can be safely discontinued during the first year, according to two studies published online Sept. 19 in the Journal of the American College of Cardiology.

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Linaclotide Relieves Symptoms of IBS With Constipation

THURSDAY, Sept. 20 (HealthDay News) -- Over 26 weeks of treatment, the peptide guanylate cyclase-C agonist linaclotide significantly improves abdominal pain and bowel symptoms in patients with irritable bowel syndrome with constipation (IBS-C), according to research published online Sept. 18 in the American Journal of Gastroenterology.

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AHA: Sesame, Rice Oil Blend Lowers Blood Pressure

THURSDAY, Sept. 20 (HealthDay News) -- Daily use of a blend of sesame and rice bran oils can significantly lower blood pressure and lipids in patients with hypertension, according to a study presented at the American Heart Association's High Blood Pressure Research Scientific Sessions, held from Sept. 19 to 22 in Washington, D.C.

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African-Americans Less Adherent to DASH Diet for Lowering BP

THURSDAY, Sept. 20 (HealthDay News) -- Greater adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is associated with larger reductions in blood pressure (BP), independent of weight loss; however, African-Americans are less likely to adhere to the DASH diet, according to a study published online Sept. 19 in the Journal of the Academy of Nutrition and Dietetics.

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Emotional Neglect in Childhood Ups Stroke Risk in Adults

THURSDAY, Sept. 20 (HealthDay News) -- Emotional neglect as a child may be tied to a higher risk of stroke as an adult, according to a study published online Sept. 19 in Neurology.

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Prognostic Factors ID'd for Q-Switched Laser Tattoo Removal

WEDNESDAY, Sept. 19 (HealthDay News) -- Several prognostic factors impact effective tattoo removal by Q-switched laser, while a new picosecond 755-nm alexandrite laser is safe and effective for removing tattoo pigment, according to two studies published online Sept. 17 in the Archives of Dermatology.

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Higher Dietary Fructose Tied to Lower Liver Energy Stores

WEDNESDAY, Sept. 19 (HealthDay News) -- Increased dietary fructose consumption may impair hepatocellular energy homeostasis, as seen with reduced levels of liver adenosine triphosphate (ATP), with lower levels seen in those with high uric acid (UA) levels, according to a study published in the September issue of Hepatology.

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Nonmedical School Vaccination Exemptions Increasing

WEDNESDAY, Sept. 19 (HealthDay News) -- Nonmedical exemptions for school vaccination requirements have increased since 2005, particularly in states with easy exemption policies, according to a letter to the editor published in the Sept. 20 issue of the New England Journal of Medicine.

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Alcohol-Related Esophageal Cancer Risk Is Reversible

WEDNESDAY, Sept. 19 (HealthDay News) -- The alcohol-related effects on esophageal cancer risk are reversible with cessation of alcohol consumption, according to research published in the July issue of Addiction.

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Nearly Half of European Mortality Due to Cancer, Chronic Disease

WEDNESDAY, Sept. 19 (HealthDay News) -- Deaths from cancer and chronic diseases accounted for approximately 42 percent of deaths in 2007 across the European Union (EU), according to a study published online Aug. 28 in BMJ Supportive & Palliative Care.

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A 5 Percent Reduction in BMI Could Alter U.S. Obesity Course

WEDNESDAY, Sept. 19 (HealthDay News) -- Obesity trends for 2030 could see considerable improvement if there was a 5 percent reduction in average body mass index for all adults by state, according to a report published online Sept. 18 by the Trust for America's Health (TFAH) and the Robert Wood Johnson Foundation (RWJF).

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New Guidelines Issued for Pediatric Fever and Neutropenia

WEDNESDAY, Sept. 19 (HealthDay News) -- New evidence-based guidelines have been compiled on the management of fever and and neutropenia (FN) in children with cancer and/or who are undergoing hematopoietic stem-cell transplantation; the guidelines were published online Sept. 17 in the Journal of Clinical Oncology.

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More Cardio-Related Life Years Lost at Extreme Temperatures

WEDNESDAY, Sept. 19 (HealthDay News) -- Cold spells and heat waves increase the number of life years lost from cardiovascular disease, with more of an increase seen during heat waves, according to research published in the September issue of Circulation: Cardiovascular Quality and Outcomes.

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Quitting Smoking Is Tough for Teens, Too

TUESDAY, Sept. 18 (HealthDay News) -- Teenagers mostly experience the same negative effects of smoking abstinence and withdrawal as adults, according to a study published online Sept. 4 in Nicotine & Tobacco Research.

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Adipose Tissue Distribution Aids Diabetes Risk Determination

TUESDAY, Sept. 18 (HealthDay News) -- Obese adults with dysfunctional adiposity (excess visceral body fat distribution and insulin resistance) are more likely to develop type 2 diabetes than obese adults with general adiposity, according to a study published in the Sept. 19 issue of the Journal of the American Medical Association, a theme issue on obesity.

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Bisphenol A Linked to Obesity in Children and Teens

TUESDAY, Sept. 18 (HealthDay News) -- Children and adolescents in the United States with elevated levels of urinary bisphenol A (BPA), a ubiquitous breakdown product of coatings used in food and beverage containers, are about twice as likely to be obese, according to a study published in the Sept. 19 issue of the Journal of the American Medical Association, a theme issue on obesity.

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Premature Death Rate Higher in People Who Self-Harm

TUESDAY, Sept. 18 (HealthDay News) -- People who self-harm have over three-fold higher rates of premature death, from both natural and external causes, according to a study published online Sept. 18 in The Lancet.

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VTE Risk Varies by Hormone Therapy Formulation

TUESDAY, Sept. 18 (HealthDay News) -- The risk of venous thromboembolism (VTE) in postmenopausal women differs considerably according to the formulation of hormone therapy (HT) used, with the highest VTE risk seen in users of oral estrogen-progestin HT containing medroxyprogesterone acetate, according to research published online Sept. 10 in the Journal of Thrombosis and Haemostasis.

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L-Carnitine Does Not Reduce Cancer-Related Fatigue

TUESDAY, Sept. 18 (HealthDay News) -- Patients with invasive malignancies who take L-carnitine supplements do not experience a reduction in fatigue, pain, or depression, according to research published online Sept. 17 in the Journal of Clinical Oncology.

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Resuming Warfarin After GI Bleed Cuts Mortality

TUESDAY, Sept. 18 (HealthDay News) -- In the 90 days following a gastrointestinal tract bleeding (GIB) event, patients who do not resume warfarin therapy experience an increased rate of thrombosis and death, according to research published online Sept. 17 in the Archives of Internal Medicine.

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Hip Circumference Inversely Tied to Diabetes Risk

TUESDAY, Sept. 18 (HealthDay News) -- There is an inverse relationship between hip circumference and risk of type 2 diabetes mellitus (T2DM), according to a meta-analysis published online Sept. 3 in Obesity Reviews.

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Gout Is Primary Indication in About 0.2 Percent of ER Visits

TUESDAY, Sept. 18 (HealthDay News) -- Gout is the primary indication in about 0.2 percent of emergency department visits annually, according to a study published online Sept. 4 in Arthritis Care & Research.

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Progestogens Not Effective in Multiple Gestations

TUESDAY, Sept. 18 (HealthDay News) -- Progestogen treatment may be beneficial for pregnant women who have previously given birth to preterm babies, but does not seem to be effective for multiple gestations, according to research published online Sept. 5 in Obstetrics & Gynecology.

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Community-Based Intervention Feasible for Obese Children

MONDAY, Sept. 17 (HealthDay News) -- A community-based scalable weight-management program correlates with significant reductions in overweight status in children, according to a study published online Sept. 17 in Pediatrics.

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Cancer Incidence and Mortality Declining for Hispanics

MONDAY, Sept. 17 (HealthDay News) -- Cancer incidence and death rates seem to be declining for Hispanics, but screening use is lower than for non-Hispanic whites, according to two studies published online Sept. 17 in CA: A Cancer Journal for Clinicians.

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Maternal Vitamin D Linked to Infant Development

MONDAY, Sept. 17 (HealthDay News) -- During pregnancy, higher maternal circulating concentrations of 25-hydroxyvitamin D3 (25[OH]D3) correlates with improved mental and psychomotor development in infants, according to a study published online Sept. 17 in Pediatrics.

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No Increased Cancer Risk With Herpes Zoster Infection

MONDAY, Sept. 17 (HealthDay News) -- There is no increased risk of cancer among patients with newly diagnosed herpes zoster infection, according to a study published online Sept. 17 in CMAJ, the journal of the Canadian Medical Association.

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Ethnic Variation Seen in Level of Pancreatic Triglycerides

MONDAY, Sept. 17 (HealthDay News) -- There is considerable ethnic variation in the levels of pancreatic triglycerides (TGs) and in β-cell dysfunction, according to research published online Sept. 11 in Diabetes Care.

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Nicotine Replacement Doesn't Increase Cardio Risk After ACS

MONDAY, Sept. 17 (HealthDay News) -- Use of nicotine replacement therapy (NRT) does not increase the risk of adverse cardiovascular events in the first year following acute coronary syndromes (ACS), according to research published in the Oct. 1 issue of The American Journal of Cardiology.

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Study Looks at Pain Processing Abnormalities in Knee OA

MONDAY, Sept. 17 (HealthDay News) -- For patients with knee osteoarthritis (K-OA), the lack of correlation between clinical pain and radiographic evidence of disease severity may be due to central sensitization, according to a study published online Sept. 7 in Arthritis & Rheumatism.

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Health Ambiguity Linked to Depression in Stroke Survivors

MONDAY, Sept. 17 (HealthDay News) -- Health ambiguity, or uncertainty about the outcome of illness, is significantly associated with depression in survivors of first stroke, and this association is stronger for men than women, according to research published online Sept. 14 in the Archives of Physical Medicine and Rehabilitation.

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White Matter Structural Changes ID'd in Children With T1DM

MONDAY, Sept. 17 (HealthDay News) -- Children with type 1 diabetes have significant structural differences in the white matter of their brain compared to healthy children, which correlates with hemoglobin A1c (HbA1c) values, according to a study published online Sept. 10 in Diabetes Care.

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Review: Inhaled Analgesia Provides Pain Relief in Labor

MONDAY, Sept. 17 (HealthDay News) -- For women in labor, inhaled analgesia provides pain relief but is associated with considerable side effects, according to a study published online Sept. 12 in The Cochrane Library.

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Mechanism of Smoking-Induced Insulin Resistance Elucidated

MONDAY, Sept. 17 (HealthDay News) -- Smoking-induced insulin resistance, which improves with smoking cessation, may be due to activation of mammalian target of rapamycin (mTOR), according to a study published online Sept. 10 in Diabetes.

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Sexting Linked to Riskier Sexual Behavior in Teens

MONDAY, Sept. 17 (HealthDay News) -- Sending or receiving sexually explicit materials via cellphone, "sexting," is associated with higher reported rates of sexual activity in adolescents, according to a study published online Sept. 17 in Pediatrics.

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Researchers Quantify Impact of Sodium on BP in Children

MONDAY, Sept. 17 (HealthDay News) -- For children and adolescents, sodium intake is associated with systolic blood pressure (SBP) and the risk for pre-high blood pressure (pre-HBP) and HBP, according to a study published online Sept. 17 in Pediatrics.

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Considerable Out-of-Pocket Costs in Last Few Years of Life

MONDAY, Sept. 17 (HealthDay News) -- Out-of-pocket health care expenditures can put a significant financial burden on elderly Medicare beneficiaries in their last five years of life, according to a study published online Sept. 4 in the Journal of General Internal Medicine.

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Thyroid-Stimulating Hormone Up Over Time in Oldest Old

FRIDAY, Sept. 14 (HealthDay News) -- For the oldest old, increases in thyroid-stimulating hormone (TSH) occur over time but do not correlate with mortality, according to a study published online Aug. 9 in the Journal of Clinical Endocrinology & Metabolism.

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Lung Transplant for CF Less Likely for Medicaid Recipients

FRIDAY, Sept. 14 (HealthDay News) -- For adults with cystic fibrosis (CF), the likelihood of not being accepted for lung transplantation is higher for those with low socioeconomic status, as indicated by Medicaid status, according to a study published online Sept. 13 in the American Journal of Respiratory and Critical Care Medicine.

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Obstructive Sleep Apnea Ups Cardio Risk in the Elderly

FRIDAY, Sept. 14 (HealthDay News) -- In the elderly, untreated severe obstructive sleep apnea (OSA) is associated with an increased risk of cardiovascular death, and adequate treatment with continuous positive airway pressure (CPAP) may reduce this risk, according to research published online Sept. 13 in the American Journal of Respiratory and Critical Care Medicine.

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Spindle Abnormalities Seen in Oocytes of Severely Obese

FRIDAY, Sept. 14 (HealthDay News) -- Oocytes from severely obese women undergoing in vitro fertilization display significant spindle abnormalities, which may contribute to poor reproductive outcomes, according to a study published online Sept. 11 in Human Reproduction.

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Exposure to Air Pollution Tied to Low Vitamin D in Newborns

FRIDAY, Sept. 14 (HealthDay News) -- Exposure to two urban pollutants during pregnancy correlates with a decrease in the blood serum levels of 25-hydroxyvitamin D (25[OH]D) of newborns, according to a study published online Aug. 17 in the Journal of Clinical Endocrinology & Metabolism.

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For Youth, Only Vigorous Activity Reduces Cardiometabolic Risk

FRIDAY, Sept. 14 (HealthDay News) -- In youth, vigorous physical activity (PA), but not light or moderate PA, correlates with improved measures of cardiometabolic risk, according to research published online Sept. 10 in the Archives of Pediatrics & Adolescent Medicine.

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Disability for 15 Percent of Patients After Minor Stroke, TIA

FRIDAY, Sept. 14 (HealthDay News) -- Approximately 15 percent of patients exhibit some disability 90 days after a minor stroke or transient ischemic attack (TIA), and more than 50 percent of patients who have a recurrent event experience disability, according to a study published online Sept. 13 in Stroke.

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Job Strain Ups Risk of Coronary Heart Disease

FRIDAY, Sept. 14 (HealthDay News) -- Job strain is associated with an increase in the risk of coronary heart disease, according to a meta-analysis published online Sept. 14 in The Lancet.

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Evidence Lacking for Weight Trends After Joint Arthroplasty

FRIDAY, Sept. 14 (HealthDay News) -- There is no conclusive evidence on whether patients undergoing total joint arthroplasty (TJA) lose or gain weight after surgery, according to a study published online Sept. 7 in Clinical Orthopaedics and Related Research.

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Risk of Car Accidents Up With Antidepressant Use

FRIDAY, Sept. 14 (HealthDay News) -- There is an increased risk of motor vehicle accidents (MVAs) for patients taking antidepressants, benzodiazepines, or Z-drugs, according to a study published online Sept. 13 in the British Journal of Clinical Pharmacology.

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Higher Mortality Risk With Preoperative Hyponatremia

FRIDAY, Sept. 14 (HealthDay News) -- Patients with preoperative hyponatremia have a higher risk of 30-day mortality and morbidity, including coronary events, surgical site wound infections, and pneumonia, according to research published online Sept. 10 in the Archives of Internal Medicine.

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Antipsychotic Use Up Among U.S. Medicaid-Enrolled Youth

FRIDAY, Sept. 14 (HealthDay News) -- There has been a substantial increase in antipsychotic use among Medicaid-enrolled children in recent years, with the increase partially driven by youth with attention-deficit/hyperactivity disorder (ADHD) and those with multiple diagnoses, according to a study published online Sept. 4 in Health Services Research.

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Meta-Analysis: Acupuncture Reasonable Chronic Pain Option

THURSDAY, Sept. 13 (HealthDay News) -- Acupuncture is an effective treatment for chronic pain conditions, including back and neck pain, osteoarthritis, and chronic headache, with pain relief superior to both no-acupuncture controls and sham-acupuncture groups, according to the results of a systematic review and meta-analysis published online Sept. 10 in the Archives of Internal Medicine.

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Advertising Changes After Drug Switch to Over-the-Counter

THURSDAY, Sept. 13 (HealthDay News) -- When a drug switches from prescription-only to over-the-counter (OTC) there is a shift in the direct-to-consumer advertising (DTCA), with less presentation of potential harms and frequent omission of identification by generic names, according to a research letter published online Sept. 11 in the Journal of the American Medical Association.

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Long-Term Finasteride Doesn't Impair Quality of Life

THURSDAY, Sept. 13 (HealthDay News) -- Taking finasteride to prevent prostate cancer does not negatively affect the physical function, mental health, or vitality domains of health-related quality of life, according to a study published online Sept. 12 in the Journal of the National Cancer Institute.

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Impact of Exposure to Road Traffic Noise Quantified

THURSDAY, Sept. 13 (HealthDay News) -- Noise-impact indicators, such as the percentage of the population who are highly annoyed and who have high levels of sleep disturbance, can be valuable metrics in comparing noise equity among urban communities, according to research published online Sept. 11 in the American Journal of Preventive Medicine.

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Diabetes Outcome Better for Patients With Empathetic Docs

THURSDAY, Sept. 13 (HealthDay News) -- Physician empathy, as measured by a validated scale, correlates with clinical outcome for patients with diabetes, with better outcome for those with doctors with high empathy, according to a study published in the September issue of Academic Medicine.

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European Review: Benefits of Mammograms Outweigh Harms

THURSDAY, Sept. 13 (HealthDay News) -- For women in Europe, mammographic screening is associated with a reduction in breast cancer mortality that is greater than the potential harms of over-diagnosis and false-positive screening results (FPRs), according to a study published in the September issue of the Journal of Medical Screening.

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Review: Inflammation's Role in Obesity-Colorectal Cancer Link

THURSDAY, Sept. 13 (HealthDay News) -- A new review summarizes the ways in which inflammation and altered metabolism are associated with colorectal cancer in obese individuals; the review was published online Sept. 3 in Obesity Reviews.

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Preparation Process Eases MRI for Children With Sickle Cell

THURSDAY, Sept. 13 (HealthDay News) -- For young children with sickle cell disease (SCD), preparation and support procedures (PSP) can help reduce the need for sedation during magnetic resonance imaging (MRI) scans, according to a study published online June 19 in Pediatric Radiology.

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Promotion of Sun Safety Does Not Inhibit Outdoor Exercise

THURSDAY, Sept. 13 (HealthDay News) -- Parental perceptions of skin cancer threat do not negatively influence children's outdoor physical activity, according to a study published in the September issue of the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Thermal Sensation Spared in Nerve-Sparing Prostatectomy

THURSDAY, Sept. 13 (HealthDay News) -- Penile thermal sensory thresholds increase after non-nerve-sparing radical prostatectomy (RP) but not after the nerve-sparing procedure, according to a study published in the September issue of The Journal of Sexual Medicine.

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Diagnosis of Congenital Heart Disease Ups Maternal Depression

THURSDAY, Sept. 13 (HealthDay News) -- Mothers who receive a prenatal diagnosis of congenital heart disease (CHD) commonly report posttraumatic stress, depression, and anxiety, according to research published online Sept. 12 in The Journal of Pediatrics.

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For Obese, Body Habitus, Not BMI Impacts Op Site Infection

WEDNESDAY, Sept. 12 (HealthDay News) -- For obese patients undergoing lumbar spine fusion surgery, the skin to lamina distance and the thickness of subcutaneous fat are significant risk factors for surgical site infection (SSI), according to a study published in the Sept. 1 issue of Spine.

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Whooping Cough Vaccine Protection Short-Lived

WEDNESDAY, Sept. 12 (HealthDay News) -- After receiving the last of five required doses of pertussis vaccine, a child's protection from the disease rapidly declines, according to a study published in the Sept. 13 issue of the New England Journal of Medicine.

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Epidural Steroid Injection Impairs Hip Bone Density

WEDNESDAY, Sept. 12 (HealthDay News) -- Epidural steroid injections (ESIs) for radiculopathy negatively impact bone mineral density (BMD) in postmenopausal women, according to a study published online Sept. 3 in Spine.

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Considerable Variation Seen for Medicare Cost-Saving Program

WEDNESDAY, Sept. 12 (HealthDay News) -- There is substantial variation in the savings achieved for practice groups involved in the Medicare Physician Group Practice Demonstration (PGPD) program, designed to improve quality and slow cost growth, according to a study published in the Sept. 12 issue of the Journal of the American Medical Association.

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Vitamin A Metabolite Linked to Sex-Specific Fat Accumulation

WEDNESDAY, Sept. 12 (HealthDay News) -- An enzyme that regulates the levels of a vitamin A metabolite may play a role in explaining why women are more prone to obesity and accumulation of abdominal fat, particularly after menopause, according to a study published online Aug. 28 in Diabetes.

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Persistence of Statin Use Linked to Decreased Cancer Risk

WEDNESDAY, Sept. 12 (HealthDay News) -- There is an inverse association between statin persistence and cancer risk, particularly for hematopoietic malignancies, according to a study published in the September issue of the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Pregnancy-Associated Cancers on the Rise in Australia

WEDNESDAY, Sept. 12 (HealthDay News) -- The incidence of pregnancy-associated cancers is increasing in Australia, with the increase only partially explained by increasing maternal age, according to a study published online Sept. 5 in BJOG: An International Journal of Obstetrics and Gynaecology.

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Review: Omega-3s Do Not Reduce Risk of Cardio Events

TUESDAY, Sept. 11 (HealthDay News) -- Supplementation with omega-3 polyunsaturated fatty acids (PUFAs) is not associated with a statistically significant reduction in major cardiovascular end points, according to research published in the Sept. 12 issue of the Journal of the American Medical Association.

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No Superior Method of Adjusting Inhaled Steroids in Asthma

TUESDAY, Sept. 11 (HealthDay News) -- For adults with mild-to-moderate asthma controlled with inhaled corticosteroids, adjustment of corticosteroids based on biomarkers (exhaled nitric oxide) or symptoms does not improve the time to treatment failure compared with physician assessment-based adjustment, according to a study published in the Sept. 12 issue of the Journal of the American Medical Association.

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Less Alzheimer's Pathology With Angiotensin Receptor Blocker Use

TUESDAY, Sept. 11 (HealthDay News) -- In autopsy findings, patients treated with angiotensin receptor blockers (ARBs) show less Alzheimer's disease (AD)-related pathology, according to a study published online Sept. 10 in the Archives of Neurology.

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Adding Ketamine to Opioids Doesn't Reduce Cancer Pain

TUESDAY, Sept. 11 (HealthDay News) -- Using subcutaneously administered ketamine in a dose-escalating regimen as an adjunct to opioids and standard co-analgesics does not have any clinical benefit in relieving cancer pain, but it is associated with increased toxicity, according to research published online Sept. 10 in the Journal of Clinical Oncology.

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PTSD Seen in Nearly 20 Percent of Young Children With Cancer

TUESDAY, Sept. 11 (HealthDay News) -- Nearly 20 percent of infants and preschoolers with cancer suffer from posttraumatic stress disorder (PTSD), according to a study published online Aug. 22 in Psycho-Oncology.

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Gestational Diabetes, Poverty Link to ADHD Strengthened

TUESDAY, Sept. 11 (HealthDay News) -- The previously reported association between attention-deficit/hyperactivity disorder (ADHD) and gestational diabetes mellitus (GDM) and low socioeconomic position (SEP) has been confirmed in a large German cohort, according to a research letter published online Sept. 10 in the Archives of Pediatrics & Adolescent Medicine.

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Safe Dengue Vaccine Deemed Feasible

TUESDAY, Sept. 11 (HealthDay News) -- A safe recombinant, live, attenuated tetravalent dengue vaccine has been deemed possible, according to a study published online Sept. 11 in The Lancet.

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Costs of Neck and Back Conditions Increasing in U.S.

TUESDAY, Sept. 11 (HealthDay News) -- For individuals with back and neck conditions, costs have increased in the last decade, with the main increase due to rising medical specialist costs, according to a study published in the Sept. 1 issue of Spine.

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Acupuncture Activates Neural Responses in Parkinson's

TUESDAY, Sept. 11 (HealthDay News) -- Patients with Parkinson's disease may benefit from acupuncture treatment on acupoint GB34, with improved neural response noted after acupuncture stimulation, according to a study published in the September issue of CNS Neurosciences & Therapeutics.

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Updated Guidelines Issued for 'Strep' Diagnosis, Treatment

TUESDAY, Sept. 11 (HealthDay News) -- The Infectious Diseases Society of America recommends use of penicillin or amoxicillin as first-line treatment for culture-confirmed cases of Group A streptococcal (GAS) pharyngitis, according to updated clinical practice guidelines published online Sept. 9 in Clinical Infectious Diseases.

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Obese Teens Self-Report Eating Less Than Healthy-Weight Peers

MONDAY, Sept. 10 (HealthDay News) -- Younger obese children report consuming more daily calories than their healthy-weight peers, while obese adolescents report consuming fewer daily calories, suggesting that excessive energy intake in early childhood may lead to onset of obesity, according to a study published online Sept. 10 in Pediatrics.

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Heavy Drinking Linked to Intracerebral Bleed at Young Age

MONDAY, Sept. 10 (HealthDay News) -- Heavy alcohol intake correlates with intracerebral hemorrhage (ICH) at a younger age, according to a study published in the Sept. 11 issue of Neurology.

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NSAID Use Ups Cardiovascular Risk Up to Five Years Post-MI

MONDAY, Sept. 10 (HealthDay News) -- The increased cardiovascular risk associated with nonsteroidal anti-inflammatory drug (NSAID) use following a first myocardial infarction (MI) persists up to five years, according to a study published online Sept. 10 in Circulation.

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Antihypertensive Use in Pregnancy Increasing

MONDAY, Sept. 10 (HealthDay News) -- The prevalence of antihypertensive use in pregnancy is approaching 5 percent and is increasing, according to a study published online Sept. 10 in Hypertension.

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Cancer Survivors Uneasy With Primary Care Doctor Follow-Up

MONDAY, Sept. 10 (HealthDay News) -- Early-stage cancer survivors have concerns about receiving cancer-related follow-up care from primary care physicians, according to a study published in the September/October issue of the Annals of Family Medicine.

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Describing Fear May Regulate Emotional Aspects of Fear

MONDAY, Sept. 10 (HealthDay News) -- Verbalizing fear may play a role in regulating the emotional aspects of fear, according to a study published online Aug. 16 in Psychological Science.

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Marijuana Use Linked to Higher Risk of Testicular Cancer

MONDAY, Sept. 10 (HealthDay News) -- Marijuana use is associated with an approximately two-fold higher risk of testicular cancer, particularly nonseminoma and mixed histology tumors, according to a study published online Sept. 10 in Cancer.

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Drinking Dealcoholized Red Wine Lowers Blood Pressure

MONDAY, Sept. 10 (HealthDay News) -- Drinking dealcoholized red wine, compared with red wine or gin, decreases systolic and diastolic blood pressure, according to a study published online Sept. 6 in Circulation Research.

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Mother's Depression During Infancy Affects Child's Growth

MONDAY, Sept. 10 (HealthDay News) -- Maternal depression at nine months postpartum may negatively affect physical growth in early childhood, according to a study published online Sept. 10 in Pediatrics.

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No Long-Term Effects Seen for Letting Infants Cry Before Sleep

MONDAY, Sept. 10 (HealthDay News) -- Infant sleep training techniques employed to reduce the short- to medium-term burden of infant sleep problems do not have lasting effects, according to a study published online Sept. 10 in Pediatrics.

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AAP Updates Flu Vaccine Recommendations for Children

Michael T. Brady, M.D., and colleagues from the AAP's Committee on Infectious Diseases, updated recommendations for routine use of trivalent seasonal influenza vaccine and antiviral medications for the prevention and management of influenza in children for the 2012 to 2013 season.

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Tight Glycemic Control of Little Value Post-Pediatric Heart Op

MONDAY, Sept. 10 (HealthDay News) -- For pediatric patients, tight glycemic control does not seem to reduce morbidity after cardiac surgery, according to a study published online Sept. 7 in the New England Journal of Medicine to coincide with presentation at the Pediatric Critical Care Colloquium, held from Sept. 6 to 9 in Santa Monica, Calif.

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Early Prophylactic Tx Beneficial for Hypertrophic Cardiomyopathy

MONDAY, Sept. 10 (HealthDay News) -- Beta blockers (BBs) are effective as an early prophylactic pharmacologic treatment for patients with mild hypertrophic cardiomyopathy (HC) who have exercise-induced left ventricular outflow tract (LVOT) obstruction, according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

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Antibody Titer Prognostic in Membranous Nephropathy

FRIDAY, Sept. 7 (HealthDay News) -- Two techniques can be used to measure antiphospholipase A2 receptor (aPLA2R) antibody titers in patients with idiopathic membranous nephropathy (iMN), with antibody titers indicative of outcome, according to research published online Sept. 6 in the Journal of the American Society of Nephrology.

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Cognitive Deficits for Chemo-Treated Breast Cancer Patients

FRIDAY, Sept. 7 (HealthDay News) -- Breast cancer survivors who were previously treated with chemotherapy experience small cognitive deficits in the domains of verbal ability and visuospatial ability, according to a study published online Aug. 27 in the Journal of Clinical Oncology.

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No Gender Effect on PCI Outcome in Acute Coronary Syndrome

FRIDAY, Sept. 7 (HealthDay News) -- There are no significant gender differences in outcomes between men and women undergoing percutaneous coronary intervention (PCI) with drug-eluting stent (DES) for the treatment of acute coronary syndrome (ACS), according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

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Disengaged Preschoolers at Academic Risk

FRIDAY, Sept. 7 (HealthDay News) -- Preschoolers classified as extremely socially and academically disengaged have the lowest academic skills, compared with their peers, according to a study published online Aug. 24 in the Journal of School Psychology.

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Diagnostic Radiation Ups Breast Cancer Risk in BRCA Carriers

FRIDAY, Sept. 7 (HealthDay News) -- For BRCA1/2 mutation carriers, exposure to diagnostic radiation before age 30 correlates with a significantly increased risk of breast cancer, with a dose-response pattern, according to a study published online Sept. 6 in BMJ.

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Elevated Rheumatoid Factor Ups Risk of Developing RA

FRIDAY, Sept. 7 (HealthDay News) -- Individuals in the general population with elevated levels of rheumatoid factor have a significantly increased risk of developing rheumatoid arthritis, according to a study published online Sept. 6 in BMJ.

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Not All Docs/Nurses Want to Be Asked About Hand Hygiene

FRIDAY, Sept. 7 (HealthDay News) -- Although most health care workers (HCWs) appreciate the role of patients in preventing health care-associated infection, a considerable proportion are uncomfortable with patients asking about their hand hygiene, according to a letter published online Sept. 3 in the Archives of Internal Medicine.

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Neurocognitive Deficits Seen in Survivors of Pediatric Hodgkin's

FRIDAY, Sept. 7 (HealthDay News) -- Adult long-term survivors of childhood Hodgkin's lymphoma are at risk for neurocognitive impairment, according to research published online Sept. 4 in the Journal of Clinical Oncology.

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Good Long-Term Prognosis for Benign IgA Nephropathy

FRIDAY, Sept. 6 (HealthDay News) -- The long-term prognosis for Caucasian patients with immunoglobulin A (IgA) nephropathy with benign presentation (consisting of only minor urinary abnormalities and normal renal function) is excellent, without special treatment, according to research published online Sept. 6 in the Journal of the American Society of Nephrology.

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Antiretrovirals Increasingly Used for HIV in the U.S.

FRIDAY, Sept. 7 (HealthDay News) -- Since 2000, more HIV-infected patients in the United States are receiving antiretroviral treatment, viral load has fallen, and CD4 counts at death have risen, according to a study published in the Sept. 4 issue of the Annals of Internal Medicine.

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Fructose Consumption Impairs Insulin Sensitivity

FRIDAY, Sept. 7 (HealthDay News) -- High levels of fructose can affect hepatic insulin sensitivity, while even moderate consumption of fructose and sucrose can significantly alter lipid profiles in healthy young men, according to research published online Aug. 28 in Diabetes Care.

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Imaging Device Quantifies Change in Port Wine Stains

FRIDAY, Sept. 7 (HealthDay News) -- A newly developed spatial frequency domain imaging (SFDI) device can be used to quantify biochemical compositional changes in port wine stain (PWS) lesions after laser therapy, according to a study published online Aug. 21 in Lasers in Surgery and Medicine.

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Teens More Likely to Smoke if They Think Their Friends Smoke

FRIDAY, Sept. 7 (HealthDay News) -- Peer influence and social context impact adolescent smoking behaviors, with popular teenagers and adolescents who think their friends smoke more likely to become smokers, according to a study published online Sept. 6 in the Journal of Adolescent Health.

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Fetal Well-Being Generally Fine After Strenuous Exercise

FRIDAY, Sept. 7 (HealthDay News) -- In general, fetal well-being is fine after strenuous exercise in both active and inactive pregnant women, according to a study published in the September issue of the American Journal of Obstetrics & Gynecology.

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Genetic Counseling Doesn't Affect Pre-Diabetes Behavior

THURSDAY, Sept. 6 (HealthDay News) -- Receiving genetic risk counseling does not significantly alter self-reported motivation or prevention program adherence for overweight individuals at risk for type 2 diabetes, according to a study published online Aug. 28 in Diabetes Care.

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Good Prognosis for Metabolically Healthy Obese

THURSDAY, Sept. 6 (HealthDay News) -- Individuals who are metabolically healthy but obese have a better prognosis than metabolically abnormal, obese adults; and for adults with acute coronary syndrome (ACS), mortality follows a U-shaped pattern with increasing body mass index (BMI), according to two studies published online Sept. 4 in the European Heart Journal.

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Characteristics of Long-Term Gastric Cancer Survivors ID'd

THURSDAY, Sept. 6 (HealthDay News) -- Patients with gastric and gastroesophageal junction (GEJ) cancer who survive for longer than three years after diagnosis seem to have distinct demographic and pathologic characteristics, compared with those who do not survive, according to research published online Sept. 4 in the Journal of Clinical Oncology.

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Prevalence of Diagnostic Errors in the ICU Assessed

THURSDAY, Sept. 6 (HealthDay News) -- Diagnostic errors in the intensive care unit (ICU) are prevalent, with 28 percent of autopsies reporting at least one misdiagnosis, according to a study published online July 21 in BMJ Quality & Safety.

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Score Can Assess One-Year Risk of Serious Infection in RA

THURSDAY, Sept. 6 (HealthDay News) -- A risk score based on rheumatoid arthritis (RA) disease characteristics and comorbidities has been developed and validated for assessing the one-year risk of serious infection, according to research published in the September issue of Arthritis & Rheumatism.

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Prone-Position Breast Radiation Avoids Heart, Lung Exposure

THURSDAY, Sept. 6 (HealthDay News) -- For most women with breast cancer, prone positioning during computed tomography (CT) simulation scans correlates with a reduction in the amount of heart and lung irradiation, according to a research letter published in the Sept. 5 issue of the Journal of the American Medical Association.

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Maternal Smoking Link to Teen Obesity Mediated by Fat Intake

THURSDAY, Sept. 6 (HealthDay News) -- The increased risk of obesity seen in adolescents who experienced prenatal exposure to maternal cigarette smoking (PEMCS) is associated with enhanced dietary intake of fat, which may be partially mediated by changes in the amygdala, according to research published online Sept. 3 in the Archives of General Psychiatry.

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Ginkgo Biloba Extract Does Not Cut Progression to Alzheimer's

THURSDAY, Sept. 6 (HealthDay News) -- For elderly adults with memory complaints, use of standardized ginkgo biloba extract is no better than placebo for reducing the incidence of Alzheimer's disease, according to a study published online Sept. 6 in The Lancet Neurology.

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Dynamic Diffuse Optical Tomography Can Diagnose PAD

THURSDAY, Sept. 6 (HealthDay News) -- Dynamic diffuse optical tomography (DDOT), a noninvasive, non-ionizing imaging modality, may be a useful new tool for diagnosing peripheral arterial disease (PAD), even in patients with diabetes, according to a study published in the Sept. 1 issue of Biomedical Optics Express.

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Nearly Half of Teens With Autism Are Victims of Bullying

THURSDAY, Sept. 6 (HealthDay News) -- Nearly half of adolescents with autism spectrum disorders (ASDs) are victims of bullying, according to research published online Sept. 3 in the Archives of Pediatrics & Adolescent Medicine.

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Congenital Disease Linked to Adipocyte Development

THURSDAY, Sept. 6 (HealthDay News) -- Some patients with congenital generalized lipodystrophy (CGL), who lack adipocytes and develop severe insulin resistance, have a defect in adipocyte development that can be partially reversed, according to a study published online Aug. 28 in Diabetes.

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Simple Eye Tracking Can Identify Neurological Disorders

THURSDAY, Sept. 6 (HealthDay News) -- Neurological disorders such as Parkinson's disease and attention-deficit/hyperactivity disorder (ADHD) can be detected with high accuracy by tracking eye movements while watching television, according to a study published online Aug. 27 in the Journal of Neurology.

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Remodeling Starts Within 48 Hours of Cardiac Injury

THURSDAY, Sept. 6 (HealthDay News) -- After cardiac injury, signs of remodeling are observed as early as 48 hours, and include structural changes and enlargement of the heart, and associated changes in cell populations, according to a study published online Sept. 4 in The American Journal of Pathology.

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Perfluorooctanoic Acid Level Tied to Cardiovascular Disease

WEDNESDAY, Sept. 5 (HealthDay News) -- Levels of perfluorooctanoic acid (PFOA), found in household consumer products, correlate positively with cardiovascular disease (CVD) and peripheral arterial disease (PAD), independently of other variables, according to a study published online Sept. 3 in the Archives of Internal Medicine.

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Alzheimer's, ALS Death Rates Up for Football Players

WEDNESDAY, Sept. 5 (HealthDay News) -- Neurodegenerative mortality is about three times higher among retired National Football League players, with Alzheimer's disease and amyotrophic lateral sclerosis mortality even higher, compared to the general U.S. population, according to a study published online Sept. 5 in Neurology.

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Intermittent ADT Noninferior to Continuous ADT for Prostate CA

WEDNESDAY, Sept. 5 (HealthDay News) -- In men with prostate cancer who have rising prostate-specific antigen (PSA) levels after radiotherapy, overall survival is similar if they receive intermittent or continuous androgen-deprivation therapy, according to a study published in the Sept. 6 issue of the New England Journal of Medicine.

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Rates of Medical Exemptions for School Immunization Low

WEDNESDAY, Sept. 5 (HealthDay News) -- Rates of medical exemptions from vaccinations required for entry to kindergarten are higher in states with easier criteria to obtain them, according to a study published online Aug. 29 in The Journal of Infectious Diseases.

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Language Barrier Linked to Poorer Asthma Outcomes

WEDNESDAY, Sept. 5 (HealthDay News) -- For elderly patients with asthma, limited English proficiency correlates with poorer outcomes, according to a study published in the September issue of the Annals of Allergy, Asthma & Immunology.

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Clopidogrel After MI Less Effective in Diabetes Patients

WEDNESDAY, Sept. 5 (HealthDay News) -- Clopidogrel therapy following a heart attack does less to reduce the risk of death in patients with diabetes than in those without diabetes, according to a study published in the Sept. 5 issue of the Journal of the American Medical Association.

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Reciprocal Increased Risk of Parkinson's, Prostate Cancer

WEDNESDAY, Sept. 5 (HealthDay News) -- Patients with Parkinson's disease (PD) have a significantly increased risk of prostate cancer and melanoma, which extends to their third-degree relatives, and there is evidence of a reciprocal risk, according to a study published online Sept. 3 in the Archives of Neurology.

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Hospitals Vary in Resuscitation Times for Cardiac Arrest

WEDNESDAY, Sept. 5 (HealthDay News) -- For patients with in-hospital cardiac arrest, the duration of resuscitation attempts varies between hospitals, with increased duration of resuscitation linked to improved survival, according to a study published online Sept. 5 in The Lancet.

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Child Glucocorticoid Use Linked to Reduced Adult Height

WEDNESDAY, Sept. 5 (HealthDay News) -- Inhaled glucocorticoids taken for childhood asthma are associated with a reduction in adult height, according to a study published online Sept. 3 in the New England Journal of Medicine to coincide with presentation at the annual meeting of the European Respiratory Society, held from Sept. 1 to 5 in Vienna.

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Assisted Listening Devices Benefit Children With Dyslexia

WEDNESDAY, Sept. 5 (HealthDay News) -- For children with dyslexia, the use of assistive listening devices (classroom frequency modulation [FM] systems) reduces auditory processing variability, with concomitant improvements in reading and phonological awareness, according to a study published online Sept. 4 in the Proceedings of the National Academy of Sciences.

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Combat Stress Affects Soldiers' Cognitive Function

WEDNESDAY, Sept. 5 (HealthDay News) -- Combat stress has adverse effects on the mesofrontal circuit of the brain that are partially reversible, according to research published online Sept. 3 in the Proceedings of the National Academy of Sciences.

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Quitting Smoking Cuts Elevated Subarachnoid Hemorrhage Risk

WEDNESDAY, Sept. 5 (HealthDay News) -- Cigarette smoking increases the risk of subarachnoid hemorrhage (SAH) in a dose-responsive manner, and cessation correlates with a reduction in SAH risk, according to a study published online Aug. 30 in the Journal of Neurology, Neurosurgery & Psychiatry.

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Themes Identified for Improving End-of-Life Care in ER

WEDNESDAY, Sept. 5 (HealthDay News) -- Major and minor themes have been identified by emergency nurses who often provide end-of-life (EOL) care in the emergency department setting, according to a study published in the September issue of the Journal of Emergency Nursing.

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Vitamin D Repletion Offers No Short-Term Benefit in Lipids

TUESDAY, Sept. 4 (HealthDay News) -- For vitamin D deficient adults, repletion of vitamin D is not associated with short-term improvement in the lipid profile, according to a study published online Sept. 4 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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Unrecognized MI Prevalent in Older Adults, Ups Mortality

TUESDAY, Sept. 4 (HealthDay News) -- For older patients, the prevalence of unrecognized myocardial infarction (UMI), as assessed by cardiac magnetic resonance (CMR) imaging, is higher than that of recognized myocardial infarction (RMI) and correlates with increased mortality, according to a study published in the Sept. 5 issue of the Journal of the American Medical Association.

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No Increased Risk of Cancer With Biologics in Rheumatoid Arthritis

TUESDAY, Sept. 4 (HealthDay News) -- For patients with rheumatoid arthritis (RA), the use of biologic response modifiers (BRMs) for at least six months is not associated with an increased risk of malignancy compared with placebo or other disease-modifying antirheumatic drugs (DMARDs), according to a study published in the Sept. 5 issue of the Journal of the American Medical Association.

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Over Half of U.S. Adults With HTN Do Not Have It Under Control

TUESDAY, Sept. 4 (HealthDay News) -- Of U.S. adults with hypertension, more than half have uncontrolled hypertension, yet the majority report having a usual source of care and health insurance, according to a study published in the Sept. 4 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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Pulmonary Artery Enlargement Predicts Exacerbation in COPD

TUESDAY, Sept. 4 (HealthDay News) -- For patients with chronic obstructive pulmonary disease (COPD), computed tomographic (CT) measurement of pulmonary artery enlargement, as determined by a ratio of the diameter of the pulmonary artery to the diameter of the aorta (PA:A) of >1, correlates with severe exacerbations, according to a study published online Sept. 3 in the New England Journal of Medicine to coincide with presentation at the annual meeting of the European Respiratory Society, held from Sept. 1 to 5 in Vienna.

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Addition of Tiotropium Effective in Poorly Controlled Asthma

TUESDAY, Sept. 4 (HealthDay News) -- For patients with poorly controlled asthma, the addition of tiotropium to standard therapy is beneficial, according to a study published online Sept. 3 in the New England Journal of Medicine to coincide with presentation at the annual meeting of the European Respiratory Society, held from Sept. 1 to 5 in Vienna.

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Organic Food Does Not Seem to Be Nutritionally Superior

TUESDAY, Sept. 4 (HealthDay News) -- Based on the published literature, there is a lack of evidence for the health benefits of organic food, according to a review published in the Sept. 4 issue of the Annals of Internal Medicine.

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Metabolic Syndrome Affects Teens' Cognitive Performance

TUESDAY, Sept. 4 (HealthDay News) -- There is evidence for lower cognitive performance and changes in the brain's structural integrity among adolescents with metabolic syndrome (MetS), according to a study published online Sept. 3 in Pediatrics.

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Plasma Glucose Tied to Atrophy in Hippocampus, Amygdala

TUESDAY, Sept. 4 (HealthDay News) -- For cognitively healthy individuals without type 2 diabetes, high plasma levels within the normal range are associated with atrophy in the hippocampus and amygdala, according to a study published in the Sept. 4 issue of Neurology.

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Elderly Discharged Home Do Well After Heart Valve Surgery

TUESDAY, Sept. 4 (HealthDay News) -- People over the age of 80 generally do well after aortic or mitral valve replacement surgery, especially if they are discharged home, according to a study published in the September issue of The Annals of Thoracic Surgery.

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Gene Variant More Common in Internet Addicts

TUESDAY, Sept. 4 (HealthDay News) -- A variant of a gene implicated in anxiety and addiction (nicotinic acetylcholine receptor subunit alpha 4 [CHRNA4]) is more frequent in people addicted to the Internet, particularly females, according to a study published in the September issue of the Journal of Addiction Medicine.

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Sleep Problems in Young Children Tied to Special Ed Need

TUESDAY, Sept. 4 (HealthDay News) -- A history of either sleep-disordered breathing (SDB) or behavioral sleep problems (BSPs) through the age of 5 years is associated with an increased likelihood of special educational need (SEN) at 8 years of age, according to a study published online Sept. 3 in Pediatrics.

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Bottle-Feeding Linked to Increased Pyloric Stenosis Risk

TUESDAY, Sept. 4 (HealthDay News) -- Bottle-fed infants have a significantly increased risk of developing pyloric stenosis (PS) in the first few months after birth, compared with infants who are not bottle-fed, according to a study published online Sept. 3 in Pediatrics.

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Stressful Lifestyle, Type A Behavior Linked to Stroke

MONDAY, Sept. 3 (HealthDay News) -- Stressful habits and type A behavior correlate with an increased risk of stroke, according to a study published online Aug. 27 in the Journal of Neurology, Neurosurgery & Psychiatry.

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In RA, Hand Surgery Improves Function, Appearance

MONDAY, Sept. 3 (HealthDay News) -- Treating rheumatoid arthritis (RA) patients with severe hand deformities with a silicone metacarpophalangeal joint arthroplasty (SMPA) procedure produces significant, long-term improvement in hand function and appearance, according to research published in the September issue of Arthritis Care & Research.

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