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Videocapsule Endoscopy Effective for Celiac Disease

Technique examines entire small bowel and helps diagnose the disease

FRIDAY, Aug. 10 (HealthDay News) -- Videocapsule endoscopy, which examines the entire small bowel, has a high sensitivity and specificity in detecting celiac disease, researchers report in the August issue of the American Journal of Gastroenterology.

Roberto de Franchis, M.D., from the University of Milan in Italy, and colleagues performed upper gastrointestinal endoscopy and videocapsule endoscopy in 43 patients with suspected celiac disease.

The researchers found that 32 patients had celiac disease based on duodenal histology. Videocapsule endoscopy had a sensitivity of 87.5 percent, a specificity of 90.9 percent, a positive predictive value of 96.5 percent, and a negative predictive value of 71.4 percent for detecting celiac disease.

"Videocapsule endoscopy shows good sensitivity and excellent specificity for the detection of villous atrophy in patients with suspected celiac disease," de Franchis and colleagues conclude.

Abstract
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