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Rate of Missed Adenomas >5 mm Similarly Low for BBPS 2, 3

Significantly higher rate of missed adenomas in colon segments with Boston Bowel Prep Scale score of 1

digestive system

FRIDAY, Feb. 12, 2016 (HealthDay News) -- The rate of missed adenomas larger than 5 mm is similarly low for men with Boston Bowel Prep Scale (BBPS) scores of 2 or 3, according to a study published in the February issue of Gastroenterology.

Brian T. Clark, M.D., from the Yale School of Medicine in New Haven, Conn., and colleagues collected data from 438 men who underwent screening or surveillance colonoscopies and then repeat colonoscopy examinations within 60 days (1,161 colon segments total). The authors examined the proportion of colon segments with adenomas larger than 5 mm that were missed in the first examination, suggesting that the miss rate would be noninferior for segments with BBPS scores of 2 versus those with BBPS scores of 3 (noninferiority margin, <5 percent).

The researchers found that the adjusted proportion of missed adenomas greater than 5 mm was 5.2 percent for segments with BBPS scores of 2 and 5.6 percent for segments with BBPS scores of 3, meeting noninferiority criteria (difference of −0.4 percent; 95 percent confidence interval, −2.9 to 2.2 percent). The proportion of segments with BBPS scores of 1 that had missed adenomas larger than 5 mm was higher than segments with BBPS scores of 3 or 2 (15.9 versus 5.6 and 5.2 percent, respectively).

"This finding supports a recommendation for early repeat colonoscopic evaluation in patients with a BBPS score of 0 or 1 in any colon segment," the authors write.

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