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ACG: Cannabis Derivative Reduces Stomach Cramps

Dronabinol study suggests that cannabinoids may modulate colonic motor function in disease

MONDAY, Oct. 23 (HealthDay News) -- The cannabis derivative dronabinol may relax the colon and reduce stomach cramping after eating, according to research presented this week at the 71st Annual Scientific Meeting of the American College of Gastroenterology in Las Vegas.

Tuba Esfandyari, M.D., of the Mayo Clinic in Rochester, Minn., and colleagues randomly assigned 52 healthy volunteers to receive either a single dose of dronabinol or placebo.

The researchers found that dronabinol relaxed the colon and reduced post-eating contractions and cramping, especially in women.

"The potential for cannabinoids to modulate colonic motor function in disease deserves a further look," Esfandyari said in a statement.

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