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Magnetic Device Beneficial for Gastroesophageal Reflux

Reduces acid exposure, reduces use of drugs, and improves quality of life

Magnetic Device Beneficial for Gastroesophageal Reflux

WEDNESDAY, Feb. 20 (HealthDay News) -- In patients with gastroesophageal reflux disease and a partial response to proton-pump inhibitors, a device to augment the lower esophageal sphincter improves reflux symptoms, reduces use of proton-pump inhibitors, and improves quality of life, according to a study published in the Feb. 21 issue of the New England Journal of Medicine.

Robert A. Ganz, M.D., from Minnesota Gastroenterology in Plymouth, and colleagues assessed the safety and effectiveness of a new magnetic device to augment the lower esophageal sphincter in 100 patients with gastroesophageal reflux disease who had a partial response to daily proton-pump inhibitors.

The researchers found that esophageal acid exposure was normalized or reduced by at least 50 percent after one year in 64 percent of patients. In addition, 93 percent of patients reduced their use of proton-pump inhibitors by at least 50 percent, and 92 percent of patients improved their quality-of-life scores by at least 50 percent after one year. Dysphagia was the most frequent adverse event. Six patients had serious adverse events and six patients had the device removed.

"In this single-group evaluation of 100 patients before and after sphincter augmentation with a magnetic device, exposure to esophageal acid decreased, reflux symptoms improved, and use of proton-pump inhibitors decreased," Ganz and colleagues write.

The study was funded by Torax Medical; several authors disclosed financial ties to pharmaceutical and medical technology companies, including Torax.

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