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Coffee Drinking Associated with Lower Liver Cancer Risk

Consuming two additional cups of coffee per day may decrease risk by 43 percent

WEDNESDAY, May 16 (HealthDay News) -- Consumption of two cups of coffee per day is associated with a lower risk of liver cancer, according to a report in the May issue of Gastroenterology.

Susanna Larsson, M.Sc., of the Karolinska Institute in Stockholm, Sweden, and a colleague reviewed epidemiologic studies and articles published between 1966 and February 2007 to evaluate the connection between liver cancer risk and coffee drinking.

The researchers found that in nine clinical studies that included 2,260 cases of primary liver cancer and hepatocellular carcinoma and 239,146 non-cases, coffee drinking appeared to be associated with a lower cancer risk. The connection was statistically significant in six of the studies.

Adding two cups of coffee a day to coffee consumption appeared to lead to a 43 percent decrease in liver cancer risk. For people with no liver cancer history, the risk ratio for liver cancer for two more daily cups of coffee was 0.69; the risk ratio for people with liver cancer history was 0.56.

"Findings from this meta-analysis suggest that an increased consumption of coffee may reduce the risk of liver cancer," the authors conclude.

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