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Polyp Size Estimates Differ Based on Method Used

CT colonography differs from colonoscopy and measurement prefixation

MONDAY, Feb. 11 (HealthDay News) -- Polyp measurements based on computed tomography (CT) colonography can differ greatly from measurements taken by colonoscopy and measurement prefixation, researchers report in the February issue of Clinical Gastroenterology and Hepatology.

Samir Gupta, M.D., from the University of Texas Southwestern Medical Center at Dallas, and colleagues compared variations in polyp size in 600 patients as determined by CT colonography, colonoscopy, and measurement prefixation with a ruler.

The researchers found CT colonography gave sizes that were 52 percent lower to 64 percent higher than prefixation estimates, which also varied when stratified by categories of clinical importance. When comparing patients with one identified polyp in the same colon segment, categorizations based on CT colonography measurements differed from prefixation measurements in 43 percent of patients.

"Future studies should clarify whether size estimation by CT colonography is sufficiently reliable as a primary factor to guide clinical management," Gupta and colleagues conclude.

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