Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for June 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Fewer Complications With NAFLD Than Hepatitis C Virus
THURSDAY, June 30 (HealthDay News) -- Patients with nonalcoholic fatty liver disease (NAFLD) with advanced fibrosis or cirrhosis may have fewer liver-related complications and less hepatocellular cancer than patients with hepatitis C virus (HCV) infection, but may have similar overall mortality, according to a study published online June 17 in Hepatology.
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Married People More Likely to Survive Colon Cancer
THURSDAY, June 30 (HealthDay News) -- Married patients with colon cancer may have improved survival rates compared to singles, according to a study published online April 5 in Cancer Epidemiology.
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Hemochromatosis Linked to Death From Yersinia Exposure
WEDNESDAY, June 29 (HealthDay News) -- Attenuated strains of virulent laboratory organisms like Yersinia pestis (Y. pestis) may pose a risk to researchers with undiagnosed hemochromatosis, according to a letter published in the June 30 issue of the New England Journal of Medicine.
Letter to the Editor
Lower Willingness to Accept ECD Liver Transplantation
WEDNESDAY, June 29 (HealthDay News) -- Patients are more willing to accept a standard criteria donor (SCD) than an expanded-criteria donor (ECD) liver transplantation (LTx), with one-third of patients having low willingness to accept ECD LTx, according to a study published online June 14 in the American Journal of Transplantation.
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Liver Fibrosis Tied to Hep C-Related Vasculitis Prognosis
FRIDAY, June 24 (HealthDay News) -- In patients with hepatitis C virus (HCV)-related systemic vasculitis, severity of liver fibrosis and vasculitis at baseline are associated with disease prognosis, according to a study published in the June issue of Arthritis & Rheumatism.
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Poor Bowel Preparation Tied to Missed Adenoma Diagnosis
FRIDAY, June 24 (HealthDay News) -- Patients who undergo colonoscopies with suboptimal preparation of the bowel may have missed adenoma diagnoses, which are detected at repeat colonoscopy, according to a study published in the June issue of Gastrointestinal Endoscopy.
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Combined Virulence Identified in E. coli O104:H4
THURSDAY, June 23 (HealthDay News) -- The high virulence of Escherichia coli (E. coli) O104:H4 may be due to the strain having combined virulence of Shiga-toxin-producing and enteroaggregative E. coli, and augmented adherence to intestinal cells, according to a study published online June 23 in The Lancet Infectious Diseases.
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Telaprevir Linked to Sustained Virologic Response in Hep C
WEDNESDAY, June 22 (HealthDay News) -- The addition of telaprevir to peginterferon and ribavirin is associated with significantly improved and sustained virologic response in patients with hepatitis C virus (HCV) genotype 1 infection who have not received previous treatment, or have a history of failed viral eradication, according to two studies published in the June 23 issue of the New England Journal of Medicine.
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Syndrome Caused by E. coli Mostly in Adults, Women
WEDNESDAY, June 22 (HealthDay News) -- A large, ongoing outbreak of the hemolytic-uremic syndrome caused by Shiga-toxin-producing Escherichia coli (E. coli) in Germany is occurring mostly in adults, primarily women, according to a study published online June 22 in the New England Journal of Medicine.
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Colorectal Surgery Linked to Venous Thromboembolism
MONDAY, June 20 (HealthDay News) -- Open colorectal (OC) surgery is associated with a significantly higher risk of perioperative venous thromboembolism (VTE) than laparoscopic colorectal (LC) surgery, according to a study published in the June issue of the Archives of Surgery.
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Newly Described Processes Limit Post-Ischemia Epithelial Damage
MONDAY, June 20 (HealthDay News) -- The epithelial lining of human jejunum is preserved during intestinal ischemia-reperfusion (IR) by rapid lamina propria contraction and zipper-like constriction of epithelial cells before they are shed into the lumen, according to a study published in the July issue of the Journal of Pathology.
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NAT Screening May Lower Undetected Hep C in Donors
MONDAY, June 20 (HealthDay News) -- Nucleic acid testing (NAT) screening for hepatitis C virus (HCV) in organ donors may be more effective than serology alone for detecting infection during the window period, according to a study published in the June issue of the American Journal of Transplantation.
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Low Risk of Malignant Progression in Barrett's
FRIDAY, June 17 (HealthDay News) -- The risk of malignant progression for patients with Barrett's esophagus (BE) may be lower than previously reported, according to a study published online June 16 in the Journal of the National Cancer Institute.
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Editorial
Coffee May Improve Virologic Response to Hep C Treatment
FRIDAY, June 17 (HealthDay News) -- Patients receiving hepatitis C therapy who drink three or more cups of coffee per day are more likely to respond to treatment compared to nondrinkers, according to a study published the June issue of Gastroenterology.
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Unequal Care Access for Children With Public Insurance
THURSDAY, June 16 (HealthDay News) -- Access to outpatient care is restricted for children with public insurance compared to those with private insurance, according to a study published in the June 16 issue of the New England Journal of Medicine.
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New Rotavirus Vaccine Reduces Cases of Infant Diarrhea
WEDNESDAY, June 15 (HealthDay News) -- In Mexico and Brazil, use of the new monovalent rotavirus vaccine (RV1) is associated with a short-term risk of intussusception in vaccinated infants but prevents a far higher number of hospitalizations and deaths from diarrhea, according to a study published in the June 16 issue of the New England Journal of Medicine.
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Life Expectancy in U.S. Counties Below Many Nations
WEDNESDAY, June 15 (HealthDay News) -- Most counties within the United States fall behind the international frontier with the best life expectancies in the world, according to a study published online June 15 in Population Health Metrics.
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Similar Number for Outpatient, Inpatient Malpractice Claims
TUESDAY, June 14 (HealthDay News) -- The number of paid malpractice claims is similar in both inpatient and outpatient settings, according to a study published in the June 15 issue of the Journal of the American Medical Association.
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Endoscopic Therapy Effective for Sessile Colonic Polyps
TUESDAY, June 14 (HealthDay News) -- Large sessile colonic polyps can be managed safely and effectively by endoscopic mucosal resection (EMR), although previous attempts increase the risk of failure, according to a study published in the June issue of Gastroenterology.
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Cancer Survival Rates Lower in U.K. Than Other Countries
FRIDAY, June 10 (HealthDay News) -- Lower cancer survival rates found in the United Kingdom are not misleading, according to a study published June 9 in BMJ.
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VHA System in United States Provides Better Cancer Care
WEDNESDAY, June 8 (HealthDay News) -- The Veterans Health Administration (VHA) system in the United States provides similar or better care for older men with cancer than fee-for-service Medicare, although some new technologies are less available, according to a study published in the June 7 issue of the Annals of Internal Medicine.
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CDC: Incidence of Several Foodborne Infections Declines
TUESDAY, June 7 (HealthDay News) -- Although the incidence of several foodborne infections -- including Shiga toxin-producing Escherichia coli (STEC) O157 -- has declined over the past several years, the incidence of Salmonella infection has not decreased, according to a Vital Signs report in the June 7 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
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Youth Bear Large Burden of Global Death, Disease
TUESDAY, June 7 (HealthDay News) -- Youths between the ages of 10 and 24 years carry 15.5 percent of the global burden of disability-adjusted life-years (DALYs), according to a study published online June 7 in The Lancet.
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No Survival Benefit With Cetuximab in Colorectal Cancer
MONDAY, June 6 (HealthDay News) -- The addition of cetuximab to standard chemotherapy for the treatment of advanced colorectal cancer does not improve progression-free survival (PFS) or overall survival (OS), according to a study published online June 4 in The Lancet.
Abstract - Maughan
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Abstract - Adams
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Late-Onset GI Complications Tied to Childhood Cancers
MONDAY, June 6 (HealthDay News) -- Survivors of childhood cancer have an increased risk of developing gastrointestinal (GI) complications later in life, according to a study published in the May issue of Gastroenterology.
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Ban on Organs From HIV Donors Limits Availability
FRIDAY, June 3 (HealthDay News) -- Reversing the ban on the transplantation of organs from deceased donors infected with HIV (HIVDD) would have a far-reaching public health impact due to the existence of a substantial pool of potential donors who could potentially donate to HIV-positive recipients, according to a study published online March 28 in the American Journal of Transplantation.
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Primary Care Providers Can Treat HCV Effectively
THURSDAY, June 2 (HealthDay News) -- Hepatitis C virus (HCV) infection can be effectively treated by primary care providers trained in the Extension for Community Healthcare Outcomes (ECHO) program, according to a study published online June 1 in the New England Journal of Medicine.
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Hospital Volume May Affect Surgical Mortality Rate
WEDNESDAY, June 1 (HealthDay News) -- Mortality rates for certain high-risk surgical procedures have decreased in the United States, which is partially due to increased market concentration and hospital volume, according to a study published in the June 2 issue of the New England Journal of Medicine.
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Clinical Correlates Found for Steatohepatosis Progression
WEDNESDAY, June 1 (HealthDay News) -- Most patients with nonalcoholic steatohepatosis (NASH) who develop hepatocellular carcinoma (HCC) are male and have high rates of obesity, diabetes, and hypertension, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.
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Viral Breakthrough After Nucleos(t)ide Analog Therapy
WEDNESDAY, June 1 (HealthDay News) -- Virological breakthrough (VBT) is common in patients with chronic hepatitis B (CHB) undergoing nucleos(t)ide analog (NUC) treatment, but is not always related to antiviral drug resistance, according to a study published in the May issue of Hepatology.
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