In Elderly, Moderate Exercise Ups Cholesterol Transfer to HDL
Higher transfers of unesterified, esterified cholesterol to HDL in exercisers vs sedentary women
WEDNESDAY, July 1, 2015 (HealthDay News) -- Older women who exercise regularly have higher transfers of unesterified cholesterol (UC) and esterified cholesterol (EC) to high-density lipoprotein cholesterol (HDL-C), compared with sedentary women, according to a letter to the editor published in the June issue of the Journal of the American Geriatrics Society.
André L.L. Bachi, Ph.D., from Cruzeiro do Sul University in São Paulo, Brazil, and colleagues examined whether moderate-intensity physical activity could increase cholesterol transfer rates to HDL in older adults. Data were included from 30 women who practiced a regular exercise training program for 1.5 to five years and 30 sedentary women, who were independent and active but had not practiced regular physical activity for at least five years.
The researchers found that, compared with sedentary women, exercisers had lower body mass index and higher HDL-C, lower triacylglycerol levels, and equal low-density lipoprotein cholesterol (LDL-C). Exercisers had higher apolipoprotein (Apo) A-I, and equal Apo B. Compared with sedentary women, exercisers had higher transfers of UC and EC to HDL-C, but phospholipid transfer was lower and triacylglycerol transfer was equivalent. Exercisers had lower interleukin-6 and tumor necrosis factor-α serum concentrations compared with sedentary women.
"This study supports the benefits of moderate-intensity exercise for elderly individuals by showing that this practice increases transfers of UC and EC to the HDL fraction while diminishing phospholipid transfer," the authors write.