Drug Might Lower Heart Attack Risk

Protein inhibitor reduces inflammatory markers in those at high risk

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WEDNESDAY, May 11, 2005 (HealthDay News) -- An investigational drug called DG-031 appears to lower inflammatory markers associated with increased heart attack risk, according to a preliminary study in the May 11 issue of the Journal of the American Medical Association.

The study found that the use of DG-031 to inhibit a specific protein, called 5-lipoxygenase activating protein (FLAP), reduced levels of these inflammatory markers in people with certain genetic variants that increase their risk of heart attack.

The study was sponsored by Iceland-based deCODE genetics Inc.

Researchers are currently planning a study to determine whether DG-031 actually reduces heart attack risk.

More information

The American Heart Association has more about heart attack.

SOURCE: JAMA/Archives journals, news release, May 10, 2005

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