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September 2009 Briefing - Oncology

Here are what the editors at HealthDay consider to be the most important developments in Oncology for September 2009. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Midlife Overweight in Women Leads to Later Poorer Health

WEDNESDAY, Sept. 30 (HealthDay News) -- A woman who is overweight at midlife has significantly reduced odds of healthy survival past the age of 70, according to a study published Sept. 29 in BMJ.

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More Research Finds Limited Benefit From PSA Test

WEDNESDAY, Sept. 30 (HealthDay News) -- Men should be aware of their chances of benefits and harms from prostate-specific antigen (PSA) testing before the test, but many are not discussing screening before making the decision, according to the results of two studies in the Sept. 28 Archives of Internal Medicine.

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Bacterial Infections Are a Factor in Many H1N1 Deaths

WEDNESDAY, Sept. 30 (HealthDay News) -- Many patients who have died of H1N1 influenza this year had a bacterial co-infection that likely contributed to their deaths, according to a Sept. 29 early release of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Role of Estrogen Supported in Colorectal Cancer Survival

WEDNESDAY, Sept. 30 (HealthDay News) -- The finding that younger women with metastatic colorectal cancer (MCRC) survive longer than younger men -- which is not seen in older patients -- supports the idea that estrogen may play a role in improved outcomes in the disease, according to research published online Sept. 29 in Clinical Cancer Research.

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Bladder Cancer Surgery Delay Linked to Poorer Survival

WEDNESDAY, Sept. 30 (HealthDay News) -- In patients with bladder cancer, less delay between transurethral tumor resection and cystectomy may improve the chances of survival, particularly in those with lower stage disease, according to research published in the October issue of the Journal of Urology.

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Breast Cancer Outcome Can Be Affected by Social Support

WEDNESDAY, Sept. 30 (HealthDay News) -- Breast cancer patients who are socially isolated may be more likely to have tumor growth as a result of the stress caused by loneliness, compared to their more socially supported counterparts, according to a study in mice published online Sept. 29 in Cancer Prevention Research.

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Prognostic Tool May Benefit GI Cancer Patients

TUESDAY, Sept. 29 (HealthDay News) -- In patients who undergo surgery to remove primary gastrointestinal stromal tumors, a new computer-based tool called a nomogram accurately predicts the risk of cancer recurrence and may help clinicians determine which patients are candidates for adjuvant imatinib therapy, according to a study published online Sept. 29 in The Lancet Oncology.

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Baseline Factors May Predict Mortality Risk in Myelofibrosis

TUESDAY, Sept. 29 (HealthDay News) -- Three baseline factors in the bone marrow disease myelofibrosis can be used to identify patients at the highest risk of death, according to a study published online Sept. 28 in the Journal of Clinical Oncology.

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People Want to Know About Costly Cancer Drug Options

TUESDAY, Sept. 29 (HealthDay News) -- If they had cancer, most Australians would want to know about an expensive anticancer drug (EACD), and many would be prepared to pay for it even if they could not afford to, according to a study published online Sept. 28 in the Journal of Clinical Oncology.

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Ultrasound Found Inadequate for Lymph Node Biopsy

TUESDAY, Sept. 29 (HealthDay News) -- Ultrasound scanners currently do not have sufficient resolution to biopsy sentinel lymph nodes (SLN) for evidence of cancer metastasis and cannot replace conventional SLN biopsy, according to a study published online Sept. 28 in the Journal of Clinical Oncology.

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Biopsy Protocols Compared for Prostate Cancer Detection

TUESDAY, Sept. 29 (HealthDay News) -- Twelve-core and eight-core biopsies have similar prostate cancer detection rates for initial biopsy, but the additional transition cores provided in 12-core biopsy may be helpful in detecting missed cancers in repeat biopsies, according to a study in the October issue of the Journal of Urology.

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Recurrence of Frank Hematuria Requires Careful Assessment

MONDAY, Sept. 28 (HealthDay News) -- In patients who have an initial episode of frank hematuria without a diagnosis, followed by a later recurrence, thorough evaluation is necessary due to a substantial risk of urological cancer, according to research published in the October issue of the Journal of Urology.

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Socioeconomics Play Role in Prostate Cancer Mortality Odds

MONDAY, Sept. 28 (HealthDay News) -- Prostate cancer patients from low socioeconomic groups are more likely to die than their counterparts of high socioeconomic status, due to delayed diagnosis, poorer diagnostic methods and less invasive treatment, according to a study published online Sept. 28 in Cancer.

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Prophylactic Mastectomy Rare Among High-Risk Women

MONDAY, Sept. 28 (HealthDay News) -- It is relatively uncommon for women at high risk for breast cancer, but without diagnosed disease, to opt for prophylactic mastectomy, but women diagnosed with breast cancer are increasingly likely to undergo contralateral mastectomy, according to a study published online Sept. 28 in Cancer.

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H1N1 Virus's Genetic Makeup Appears to Be Staying Stable

MONDAY, Sept. 28 (HealthDay News) -- The genetic makeup of the H1N1 flu has remained stable, which means the yet-to-be-released vaccine is likely to be a good match for the virus, the U.S. Centers for Disease Control and Prevention announced at a Sept. 25 media briefing.

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Study Casts Further Doubt on PSA for Cancer Screening

FRIDAY, Sept. 25 (HealthDay News) -- Based on likelihood ratios, prostate specific antigen (PSA) concentrations at any cutoff value didn't meet the criteria needed for a screening test, according to research published online Sept. 24 in BMJ.

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New Paradigm for Progress in Surgery Proposed

FRIDAY, Sept. 25 (HealthDay News) -- In a series of articles in the Sept. 26 issue of The Lancet, a cohort of surgical-thought leaders proposes a new paradigm for innovation, research, and evidence-based advancement in the field of surgery.

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New Tool May Accurately Predict Cervical Cancer Risk

THURSDAY, Sept. 24 (HealthDay News) -- A new tool for assessing cervical cancer risk may offer clinicians a simpler method for making treatment decisions than commonly used management algorithms, according to an article published online Sept. 20 in The Lancet Oncology.

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Study Explores Head, Neck Cancer Radiation Completion

THURSDAY, Sept. 24 (HealthDay News) -- In patients with head and neck cancer, having surgery or chemotherapy may influence their likelihood of completing radiotherapy, according to research published in the September Archives of Otolaryngology -- Head & Neck Surgery.

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Doubling Drug Dose Beneficial in Leukemia Patients

WEDNESDAY, Sept. 23 (HealthDay News) -- Doubling the conventional dose of daunorubicin significantly improves complete remission rates and often overall survival in patients with previously untreated acute myeloid leukemia (AML), according to two studies in the Sept. 24 New England Journal of Medicine.

Abstract - Lowenberg
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Gene Mutations Linked to Hereditary Immunodeficiency

WEDNESDAY, Sept. 23 (HealthDay News) -- Gene mutations leading to a lack of DOCK8 protein in lymphocytes are associated with a hereditary combined immunodeficiency, according to a study published online Sept. 23 in the New England Journal of Medicine.

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Review Advises Hand Washing, Other Antiviral Measures

WEDNESDAY, Sept. 23 (HealthDay News) -- Hand washing, wearing a mask, and isolating potential cases are all effective in interrupting the spread of viral respiratory infections and should be given greater attention when planning for widespread outbreaks, according to research published Sept. 22 in BMJ.

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Study Finds Obesity Impairs Leukemia Treatment Response

WEDNESDAY, Sept. 23 (HealthDay News) -- Obesity may directly impair the efficacy of leukemia treatment, according to an animal study published online Sept. 22 in Cancer Research.

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Spotlight on Social Networking Use Among Medical Students

TUESDAY, Sept. 22 (HealthDay News) -- A majority of medical schools report instances of medical students posting unprofessional content on social networking Web sites, including some instances of violations of patient confidentiality, according to a report in the Sept. 23/30 issue of the Journal of the American Medical Association.

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Physician Medical Errors Linked to Fatigue and Burnout

TUESDAY, Sept. 22 (HealthDay News) -- The incidence of medical error is associated with a host of factors related to physician fatigue, burnout, and mental and emotional well-being, according to a study in the Sept. 23/30 issue of the Journal of the American Medical Association.

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Vitamin D Supplementation Helps Avert Melanoma Relapse

TUESDAY, Sept. 22 (HealthDay News) -- Vitamin D supplementation may help prevent melanoma relapse and increase the chance that tumors will be thinner if relapse does occur, according to research published online Sept. 21 in the Journal of Clinical Oncology.

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HPV Load in Cervical Tumors Can Affect Relapse, Survival

TUESDAY, Sept. 22 (HealthDay News) -- Uterine cervical cancer patients with low human papillomavirus (HPV) viral loads in their tumors have a higher risk of cancer relapse after treatment with radiotherapy and exhibit worse disease-free survival, according to a study published online Sept. 21 in the Journal of Clinical Oncology.

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Breast Cancer Prevention Drugs and Cognition Studied

TUESDAY, Sept. 22 (HealthDay News) -- The selective estrogen receptor modulators tamoxifen and raloxifene, used for breast cancer prevention in postmenopausal women, have similar effects on cognition, according to a study published online Sept. 21 in the Journal of Clinical Oncology.

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Tanning May Put Very-Light-Skinned Youth at Higher Risk

MONDAY, Sept. 21 (HealthDay News) -- Very-light-skinned children who tan develop more nevi than their counterparts who do not, which may indicate increased risk of developing melanoma when they are older, according to a study published in the September issue of the Archives of Dermatology, while another study in the same issue recommends more states implement controls on youth access to tanning facilities.

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Frequent Dosing Can Improve Survival in Ovarian Cancer

MONDAY, Sept. 21 (HealthDay News) -- More frequent dosing with paclitaxel combined with carboplatin improves survival in women with advanced ovarian cancer, according to a study published early online Sept. 20 in The Lancet to coincide with the European Cancer Organisation meeting in Berlin.

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Papers Look at Lung Cancer Factors in Never Smokers

MONDAY, Sept. 21 (HealthDay News) -- A guide to lung cancer in never smokers offers an overview of the disease, a description of the epidemiology and risk factors for lung cancer in those who have never smoked, and differences in molecular profiles between this group and smokers, as published in three papers in the Sept. 15 Clinical Cancer Research.

Abstract - Samet
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Drug May Improve Outcomes for CNS Lymphomas

MONDAY, Sept. 21 (HealthDay News) -- The addition of high-dose cytarabine to standard methotrexate treatment of primary central nervous system lymphomas greatly improves remission rates, according to a study published early online Sept. 20 in The Lancet to coincide with the European Cancer Organisation meeting in Berlin.

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Hormone Replacement Linked to Lung Cancer Deaths

MONDAY, Sept. 21 (HealthDay News) -- Treatment with estrogen plus progestin in postmenopausal women is associated with higher death rates from lung cancer, according to a study published early online Sept. 20 in The Lancet to coincide with the European Cancer Organisation meeting in Berlin. In a related study published the same day in the The Lancet, researchers found that pemetrexed is effective maintenance therapy in patients with advanced non-small-cell lung cancer.

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Patients' Mistrust Affects Use of Breast Cancer Treatments

MONDAY, Sept. 21 (HealthDay News) -- Women's negative attitudes toward treatment and mistrust of the medical delivery system are associated with underuse of adjuvant treatment for early-stage breast cancer, according to a study published online Sept. 21 in the Journal of Clinical Oncology.

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Mediterranean Diet More Costly to Follow Than Western

FRIDAY, Sept. 18 (HealthDay News) -- Spanish university graduates who tended to follow a Mediterranean diet spent more money for their food than those following a western diet, according to a study published online Sept. 17 in the Journal of Epidemiology and Community Health.

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Information Limited on Testing Technologies in Breast Cancer

THURSDAY, Sept. 17 (HealthDay News) -- Although information about the clinical use of human epidermal growth factor receptor 2 (HER2) testing strategies in breast cancer patients is limited, evidence suggests that there are significant variations in testing practices and important knowledge gaps, according to a study published online Sept. 14 in Cancer.

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Smoking, Alcohol Linked to Earlier Cancer Diagnosis

THURSDAY, Sept. 17 (HealthDay News) -- Patients with pancreatic cancer who smoke cigarettes and drink alcohol are diagnosed at a younger age than patients who do not smoke or drink, according to a study in the September issue of Clinical Gastroenterology and Hepatology.

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Taxes on Sugared Sodas Could Cut Consumption

WEDNESDAY, Sept. 16 (HealthDay News) -- Imposing a tax on sugar-sweetened beverages could reduce consumption and generate income for obesity reduction and healthy eating education interventions, according to an article published online Sept. 16 in the New England Journal of Medicine.

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Hispanic/Latino Community Has Unique Cancer Profile

WEDNESDAY, Sept. 16 (HealthDay News) -- Hispanics and Latinos have a unique cancer profile that means they are less likely to get the four most common cancers, but are more likely to develop cancers related to infection, according to a report published Sept. 15 by the American Cancer Society.

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Cancer Drug May Increase Risk of Carpal Tunnel Syndrome

WEDNESDAY, Sept. 16 (HealthDay News) -- Treatment of postmenopausal breast cancer with an aromatase inhibitor increases the risk of developing carpal tunnel syndrome (CTS), although cases are mild to moderate and do not lead to patients stopping treatment, according to a study published online Sept. 14 in the Journal of Clinical Oncology.

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Diabetes Drug Combination Can Eliminate Breast Cancers

WEDNESDAY, Sept. 16 (HealthDay News) -- Breast cancers are virtually eliminated in mice treated with a combination of the diabetes drug metformin and the chemotherapy drug doxorubicin due to their ability to kill cancer stem cells, according to a study published online Sept. 14 in Cancer Research.

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More Evidence Needed on Charged-Particle Therapy

WEDNESDAY, Sept. 16 (HealthDay News) -- Research comparing the safety and effectiveness of charged-particle radiation therapy with other treatments for cancer is scant, pointing to a need for comparative studies, preferably randomized trials, according to research published online Sept. 15 in the Annals of Internal Medicine.

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Lymphoma Death Risk Higher in Rural Area, Local Provider

WEDNESDAY, Sept. 16 (HealthDay News) -- Lymphoma patients in rural areas who are treated by community-based providers are at greater risk of death than rural patients treated by university-based providers and urban patients treated by either community- or university-based providers, according to a study published online Sept. 14 in the Journal of Clinical Oncology.

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Lipid Screening Cost Effective for Hodgkin's Lymphoma

WEDNESDAY, Sept. 16 (HealthDay News) -- Lipid screening in survivors of Hodgkin's lymphoma who receive mediastinal irradiation, which increases their risk of coronary heart disease, is most cost effective if done every three years, according to a study published online Sept. 14 in the Journal of Clinical Oncology.

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FDA Approves Four Vaccines for H1N1 Influenza

TUESDAY, Sept. 15 (HealthDay News) -- The U.S. Food and Drug Administration has approved four H1N1 influenza vaccines, according to a Sept. 15 news release issued by the agency.

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Conservative Management in Prostate Cancer Feasible

TUESDAY, Sept. 15 (HealthDay News) -- In older men with localized prostate cancer, conservative management is associated with significantly improved 10-year outcomes compared to earlier eras, according to a study published in the Sept. 16 issue of the Journal of the American Medical Association.

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Three Medications Beneficial in Breast Cancer Prevention

TUESDAY, Sept. 15 (HealthDay News) -- Three medications -- the selective estrogen receptor modulators tamoxifen and raloxifene, and tibolone, a drug not approved in the United States but used in many other countries to treat menopausal symptoms -- may reduce the risk for primary breast cancer. However, the three drugs are variously associated with an increased risk of thromboembolic events, endometrial cancer, or stroke, according to a study published online Sept. 15 in the Annals of Internal Medicine.

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Joint Pain Can Accompany Aromatase Therapy

TUESDAY, Sept. 15 (HealthDay News) -- Postmenopausal breast cancer patients receiving aromatase inhibitors (AIs) adjunctively can experience joint pain, marked by fluid buildup in joints, localized inflammation of tendon sheaths, and carpal tunnel syndrome, according to a study published online Sept. 14 in the Journal of Clinical Oncology.

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Drug Interaction E-Alerts Show Benefit to Patient Safety

MONDAY, Sept. 14 (HealthDay News) -- Drug interaction alerts from electronic prescribing likely improve patient safety and reduce costs in outpatient care, despite the fact that over 90 percent of the alerts are overridden by physicians, according to a study in the Sept. 14 issue of Archives of Internal Medicine.

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Depression May Help Predict Mortality in Cancer Patients

MONDAY, Sept. 14 (HealthDay News) -- In cancer patients, depression is associated with a statistically significant but relatively small increased risk of death, but it is not associated with an increased risk of disease progression, according to a study published online Sept. 14 in Cancer.

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FDA Clears Test to Help Detect Ovarian Cancer

MONDAY, Sept. 14 (HealthDay News) -- On Sept. 11, the U.S. Food and Drug Administration cleared OVA1, a test that helps detect ovarian cancer in women with pelvic masses requiring surgery. OVA1 was developed by Vermillion Inc., headquartered in Fremont, Calif., in conjunction with researchers at Johns Hopkins University in Baltimore.

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New Prostate Stem Cell May Be a Source of Cancer

MONDAY, Sept. 14 (HealthDay News) -- A new type of prostate stem cell isolated from adult mice may be a source of prostate cancer, according to a study published online Sept. 9 in Nature.

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Regimen Improves Survival in Childhood Leukemia

FRIDAY, Sept. 11 (HealthDay News) -- A dexamethasone-based chemotherapy regimen improves survival in children with acute lymphoblastic leukemia (ALL) without cranial irradiation or some routinely used chemotherapy drugs, according to a study published online Sept. 10 in The Lancet Oncology.

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Safety-Net Patients Unlikely to Undergo Colorectal Screens

FRIDAY, Sept. 11 (HealthDay News) -- Among patients served by a safety-net health system, colorectal cancer screening rates are significantly lower than the national average, according to a study published in the September issue of Cancer Epidemiology, Biomarkers & Prevention.

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Perineural Invasion Points to Colorectal Cancer Outcomes

FRIDAY, Sept. 11 (HealthDay News) -- Perineural invasion (PNI) is often not included in pathology reports for colorectal cancer, but it may serve as a predictor of outcomes in these cases, according to research published online Sept. 8 in the Journal of Clinical Oncology.

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Mutated H1N1 Virus Resistant to Antiviral Drug Oseltamivir

FRIDAY, Sept. 11 (HealthDay News) -- The discovery of H1N1 mutations resistant to the neuraminidase inhibitor oseltamivir in two adolescent girls sharing a cabin at a North Carolina camp prompted a new recommendation from the U.S. Centers for Disease Control and Prevention on the proper prophylactic use of antiviral drugs, according to a case report in the Sept. 11 issue of the CDC's Morbidity and Mortality Weekly Report.

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Poverty-Mortality Association Unchanged in England

FRIDAY, Sept. 11 (HealthDay News) -- Despite myriad medical, public health, social, economic and political changes, the association between poverty and mortality in England and Wales is as strong today as it was at the start of the 20th century, according to a study published online Sept. 10 in BMJ.

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Adiponectin Associated With Childhood Lymphoma

THURSDAY, Sept. 10 (HealthDay News) -- Higher levels of adiponectin, but not leptin, are associated with childhood non-Hodgkin's lymphoma, as well as a poorer prognosis, according to research published online Sept. 8 in the Journal of Clinical Oncology.

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FDA Panel Recommends HPV Vaccine Gardasil for Males

THURSDAY, Sept. 10 (HealthDay News) -- A U.S. Food and Drug Administration advisory panel is recommending that the vaccine Gardasil be given to boys and young men to help prevent genital warts. The same panel has determined that another human papillomavirus (HPV) vaccine, Cervarix, seems safe for preventing cervical cancer in females ages 10 to 25 years.

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Lapatinib Minimally Effective Against Liver Cancer

THURSDAY, Sept. 10 (HealthDay News) -- Lapatinib is not effective in reducing disease progression in patients with advanced liver cancer, according to a study published online Sept. 8 in Clinical Cancer Research.

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Study Finds Insomnia Common in Cancer Patients

WEDNESDAY, Sept. 9 (HealthDay News) -- Insomnia may be common in cancer patients in the months after surgical treatment, according to research published online Sept. 8 in the Journal of Clinical Oncology.

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In-Hospital Pediatric Diagnosis of VTE Up 70 Percent

WEDNESDAY, Sept. 9 (HealthDay News) -- Yearly pediatric hospital cases of venous thromboembolism (VTE) have risen 70 percent in this decade, with many children having coexisting chronic conditions, according to a study published online Sept. 7 in Pediatrics.

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Most H1N1 Flu Patients Don't Need Antiviral Medication

WEDNESDAY, Sept. 9 (HealthDay News) -- Antiviral medications should be used to treat H1N1 swine flu only in people who are hospitalized from the flu or are at high risk of complications from it, according to the U.S. Centers for Disease Control and Prevention.

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Higher Bone Lead Levels Linked to Higher Mortality

WEDNESDAY, Sept. 9 (HealthDay News) -- Lead concentration in the bones accumulated in prior decades of environmental exposure is associated with all-cause and all-cardiovascular mortality, according to a study published online Sept. 8 in Circulation.

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Lifestyle Factors May Affect Breast Cancer Relapse Risk

TUESDAY, Sept. 8 (HealthDay News) -- In women with estrogen receptor-positive invasive breast cancer, three potentially modifiable lifestyle factors -- obesity, current smoking, and alcohol consumption -- may increase the risk of contralateral breast cancer, according to a study published online Sept. 8 in the Journal of Clinical Oncology.

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Prostate Cancer Patients Seek Several Information Sources

FRIDAY, Sept. 4 (HealthDay News) -- Between diagnosis of local stage prostate cancer and treatment, men access an average of five information sources, according to a study published in the September issue of Urology.

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Study Supports MRI Use for Renal Lesions in Pregnancy

FRIDAY, Sept. 4 (HealthDay News) -- Magnetic resonance imaging (MRI) is acceptable imaging to be performed in women with renal lesions incidentally detected during routine antenatal ultrasonography, according to a study in the September issue of Urology.

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Findings Support Deferred Prostate Cancer Treatment

THURSDAY, Sept. 3 (HealthDay News) -- Some men with prostate cancer may safely defer treatment for years without a higher risk of metastasis or cancer mortality than those who receive initial treatment, according to research published online Aug. 31 in the Journal of Clinical Oncology.

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Breast Cancer Metastasis Gene Linked to Poor Survival

THURSDAY, Sept. 3 (HealthDay News) -- Expression of a gene involved in glucose metabolism and cell death is higher in breast cancer brain metastases compared with primary tumors, and high expression is associated with poor survival, according to a study published online Sept. 1 in Molecular Cancer Research.

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Diagnoses, Health Costs Rise in Partners of Cancer Patients

THURSDAY, Sept. 3 (HealthDay News) -- Health care use increases in partners of cancer patients following the cancer diagnosis, according to research published online Aug. 31 in the Journal of Clinical Oncology.

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Endoscopy as Effective as Surgery for Esophageal Cancer

THURSDAY, Sept. 3 (HealthDay News) -- Early-stage esophageal cancer can be removed through an endoscope rather than removing the whole esophagus, with no apparent effect on survival, according to a study in the September issue of Gastroenterology.

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Racial Disparities in Pancreatic Cancer Risk Explored

THURSDAY, Sept. 3 (HealthDay News) -- Known risk factors for pancreatic cancer do not explain why incidence of the disease is substantially higher in African-Americans versus Caucasians, according to a study published online Sept. 1 in Cancer Epidemiology, Biomarkers & Prevention.

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New Cancer Drug Targets Hedgehog Signaling Pathway

WEDNESDAY, Sept. 2 (HealthDay News) -- A new drug, GDC-0449, that targets the hedgehog pathway has shown promise in the treatment of basal-cell cancer and medulloblastoma, according to two reports and an editorial published online Sept. 2 in the New England Journal of Medicine.

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Body Mass, Weight Gain Linked to Prostate Cancer Risk

WEDNESDAY, Sept. 2 (HealthDay News) -- Men's body mass, as well as weight gain in adulthood, may affect their risk of prostate cancer, according to research published online Sept. 1 in Cancer Epidemiology, Biomarkers & Prevention.

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Blood Test May Help Identify Pancreatic Cancer

WEDNESDAY, Sept. 2 (HealthDay News) -- MicroRNA profiling in plasma may allow for the early detection and diagnosis of pancreatic cancer, according to a study published online Sept. 1 in Cancer Prevention Research.

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Nadroparin May Prevent Blood Clots During Chemotherapy

WEDNESDAY, Sept. 2 (HealthDay News) -- In patients receiving chemotherapy for metastatic or locally advanced solid cancer, nadroparin may reduce the risk of thromboembolic events, according to a study published online Sept. 1 in The Lancet Oncology.

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Academic Medical Centers Active and Diverse in Research

TUESDAY, Sept. 1 (HealthDay News) -- Research at academic medical centers is active and diverse, with nearly a quarter of life-science researchers receiving no funding, and relationships with industry more commonly seen among translational and clinical researchers than basic science researchers, according to a study in the Sept. 2 issue of the Journal of the American Medical Association.

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Prostate-Specific Antigen Test May Increase Overdiagnosis

TUESDAY, Sept. 1 (HealthDay News) -- Since the prostate-specific antigen (PSA) test was introduced, many men have been overdiagnosed with prostate cancer, according to a study published online Aug. 31 in the Journal of the National Cancer Institute.

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