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PET-CT Accurately Detects Ovarian Cancer Recurrence

Study finds a significantly higher accuracy rate compared to either CT alone or PET alone

WEDNESDAY, May 3 (HealthDay News) -- Hybrid PET-CT is more accurate than computed tomography (CT) alone or positron emission tomography (PET) alone for detecting recurrent ovarian cancer either above or below the diaphragm, according to research presented this week at the annual meeting of the American Roentgen Ray Society in Vancouver, Canada.

Sunit Sebastian, M.D., of Emory University School of Medicine in Atlanta, and colleagues reviewed 54 consecutive body CT, PET and PET-CT examinations on 53 patients presenting over a 15-month period with histologically proven ovarian cancer being evaluated for question of tumor recurrence.

For the body overall, the researchers found that PET-CT had an accuracy rate of 92 percent compared to 83 percent for CT and 77 percent for PET. In the chest, they found that PET-CT had an accuracy rate of 96 percent compared to 89 percent for CT and 90 percent for PET. In the abdomen, they found that PET-CT had an accuracy rate of 91 percent compared to 79 percent for CT and 79 percent for PET.

"We undertook this study because PET-CT is a hot and emerging imaging technique, and its use continues to be evaluated for many indications in the abdomen and pelvis. Also, on CT it is difficult many times to detect ovarian cancer recurrence because of the presence of certain metastatic deposits," Sebastian said in a statement.

Abstract (#105)

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