See What HealthDay Can Do For You
Contact Us

More Radiation Doesn't Up Survival in Low-Risk Prostate CA

But higher doses may improve survival in men with intermediate- and high-risk prostate cancers

FRIDAY, July 17, 2015 (HealthDay News) -- Higher doses of radiation may improve survival in men with intermediate- and high-risk prostate cancers, but it does not do the same for those with low-risk disease, according to a study published online July 16 in JAMA Oncology.

Anusha Kalbasi, M.D., a radiation oncology resident at the University of Pennsylvania in Philadelphia, and colleagues examined data from 42,481 prostate cancer patients. Some of the men had received the standard dose of radiation, while others received higher-dose radiation.

The researchers found that every incremental increase in radiation dose was associated with a 7.8 percent decline (for those with intermediate-risk cancer) and 6.3 percent decline (for high-risk cancer) in all-cause mortality. However, the equation changed when it came to men with low-risk prostate tumors. In those cases, using a higher dose of radiation made no difference in survival rates.

The study "raises the provocative question of whether radiation dose reduction for patients with low-risk prostate cancer could achieve similar cure rates while avoiding the increased risk of side effects associated with higher radiation doses," Kalbasi said in a university news release.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Physician's Briefing


HealthDay is the world’s largest syndicator of health news and content, and providers of custom health/medical content.

Consumer Health News

A health news feed, reviewing the latest and most topical health stories.

Professional News

A news feed for Health Care Professionals (HCPs), reviewing latest medical research and approvals.