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Antibiotics Help HIV-Infected Women With Salpingitis

But women with severe disease respond more slowly to treatment

TUESDAY, April 11 (HealthDay News) -- HIV-infected women with acute salpingitis respond to antibiotic treatment, but more slowly than uninfected women, according to research published in the April issue of Obstetrics & Gynecology.

Nelly R. Mugo, M.B., of the Kenyatta National Hospital in Nairobi, Kenya, and colleagues studied 140 women aged 18 to 40 with laparoscopically verified salpingitis. The women were treated with two grams of intravenous cefotetan and 100 milligrams of oral doxycycline every 12 hours while tuboovarian abscesses measuring 4 centimeters or more were drained.

Fifty-three of the 140 women (38 percent) were infected with HIV-1. The researchers found severe disease, including pyosalpinx and/or tuboovarian abcesses, more common in HIV-1-infected women (38 percent) than in women without HIV-1 (24 percent). Although all the women responded to antibiotics, HIV-infected women with severe salpingitis improved more slowly than uninfected women.

"Although HIV-1 infection may prolong hospitalization in women with severe salpingitis, all women hospitalized with acute salpingitis responded promptly to antibiotic therapy and surgical drainage regardless of HIV-1 infection status," the authors wrote.

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