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April 2008 Briefing - HIV & AIDS

Here are what the editors at HealthDay consider to be the most important developments in HIV & AIDS for April 2008. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Physicians Lack Feedback on Accuracy of Diagnoses

TUESDAY, April 29 (HealthDay News) -- Clinical diagnosis is a largely open-loop system in which there is no systematic way for clinicians to obtain feedback on the outcome of their diagnoses, according to an article published in a supplement to the May issue of The American Journal of Medicine.

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Inhibition of Human T-Cell Protein Blocks HIV Replication

TUESDAY, April 29 (HealthDay News) -- Inhibition of a T-cell protein that is required for T-cell activation blocks HIV replication in in vitro experiments, according to an article published online April 28 in the Proceedings of the National Academy of the Sciences Early Edition.

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Palliative Care Can Improve Patient Care Most, Poll Finds

MONDAY, April 28 (HealthDay News) -- In an international poll conducted by BMJ to determine which area of health care would enable doctors to make the greatest difference to patients, palliative care for non-malignant disease received the most votes, the BMJ Group announced at the International Forum on Quality and Safety in Health Care in Paris this week.

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FDA Approves Drug for Opioid-Induced Constipation

FRIDAY, April 25 (HealthDay News) -- The U.S. Food & Drug Administration (FDA) announced this week that it has approved Relistor (methylnaltrexone bromide) to help restore bowel function in patients with late-stage, advanced illness requiring chronic opioids for pain control.

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Clinical Observation Alone Effective in HIV Management

FRIDAY, April 25 (HealthDay News) -- For HIV patients on the World Health Organization-recommended first-line regimen of stavudine, lamivudine and nevirapine, the use of clinical observation alone does not have a significantly adverse effect on patient survival or development of resistance when compared with observation that includes monitoring of viral load or CD4 cell count, according to a study published in the April 26 issue of The Lancet.

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Individualized Health Care Budgets Improve Care

FRIDAY, April 11 (HealthDay News) -- The U.K.'s National Health Service (NHS) should allow patients individual control of their health care budgets, an approach that has been shown in pilot studies to improve outcomes and patient satisfaction in a cost-effective manner, according to an analysis published April 12 in BMJ.

Editorial

Child, Maternal Mortality Not Improving in Poorest Nations

FRIDAY, April 11 (HealthDay News) -- Despite some positive signs, progress towards meeting Millennium Development Goals for reducing maternal and child mortality in the world's poorest countries is inadequate, according to the Countdown report and other articles in a special edition of The Lancet published April 12.

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Abstract - Countdown to 2015 Core Group
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Editorial
Abstract - Masanja
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Consider Health Literacy Level When Writing for Patients

THURSDAY, April 10 (HealthDay News) -- Giving patients clearly written educational materials that convey key messages without resorting to jargon is an important part of engaging patient compliance with treatment and can contribute to health literacy, according to an article published in the April issue of Chest.

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Doctors Vote on the Ways to Make Biggest Difference

WEDNESDAY, April 9 (HealthDay News) -- The BMJ has begun accepting votes on which areas of health care allow doctors to make the biggest difference to patient care, with a shortlist of six areas each being championed by eminent doctors and researchers. The winning topic will gain special coverage in the BMJ and the BMJ Group's 24 other specialist journals and online education products.

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HIV Drugs May Increase the Risk of Heart Attack

WEDNESDAY, April 2 (HealthDay News) -- HIV patients who have taken either abacavir or didanosine for six months or less may have an increased risk of heart attack, according to study findings published online April 2 in The Lancet.

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