July 2007 Briefing - HIV & AIDS

Here are what the editors at HealthDay consider to be the most important developments in HIV & AIDS for July 2007. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Nasopharyngeal Aspiration Helps Pediatric TB Diagnosis

MONDAY, July 30 (HealthDay News) -- Nasopharyngeal aspiration (NPA) is a simple and safe method for confirming pulmonary tuberculosis in young children who have difficulty expectorating sputum, reports a study published in the August issue of Archives of Disease in Childhood.

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Kaposi Sarcoma Lesions Predominately Multiclonal

TUESDAY, July 24 (HealthDay News) -- The majority of Kaposi sarcoma lesions are multiclonal in origin, and disseminated lesions are reactive proliferations rather than true malignancies, according to a report in the July 18 issue of the Journal of the National Cancer Institute.

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Three Human Gene Variants Affect HIV-1 Load

THURSDAY, July 19 (HealthDay News) -- Variants of three genes affect the ability of HIV-infected individuals to control their viral load during the asymptomatic phase of infection, according to a study published online July 19 in Science.

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HIV Patients Can Achieve Normal CD4 Cell Counts

THURSDAY, July 19 (HealthDay News) -- In most HIV-positive patients, long-term combination antiretroviral therapy that suppresses HIV viral load to below 50 copies per milliliter may restore CD4 cell counts to levels found in HIV-negative subjects, according to study findings published online July 19 in The Lancet.

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Risk of HIV with Condom Same with or Without Diaphragm

FRIDAY, July 13 (HealthDay News) -- The use of a diaphragm and lubricant gel in addition to a condom is not more effective at reducing the risk for HIV infection in women from South Africa and Zimbabwe than using a condom alone, according to a report published online July 13 in The Lancet.

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HIV Mutates in Response to Patient's Immune System

FRIDAY, July 6 (HealthDay News) -- HIV is under immune selection based on the patient's human leukocyte antigen (HLA) type, and viral genes appear to mutate in a predictable way depending on a patient's HLA polymorphisms, according to a report published online July 6 in PLoS Pathogens.

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Merck Recalls Three Lots of Invanz Due to Glass Shards

FRIDAY, July 6 (HealthDay News) -- Three lots of Invanz (ertapenem sodium) were recalled this week due to two incidents in which pieces of broken glass were found in the reconstituted solution for injection. Merck & Co., Inc., of Whitehouse Station, N.J., issued a letter to health care professionals noting that it is working closely with the U.S. Food and Drug Administration to inform its direct customers of the recall.

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Conflict Does Not Fuel Spread of HIV

THURSDAY, July 5 (HealthDay News) -- Although it has been suggested that HIV incidence is increased by conflict and the widespread rape and population displacement that accompanies it, populations affected by war do not have a greater incidence of HIV infection than those not affected by war, according to a report published in the June 30 issue of The Lancet.

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