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Vulvar, Vaginal Tumor Risk Higher in Women with HIV

HIV-infected women should be carefully evaluated during gynecologic exams

THURSDAY, May 4 (HealthDay News) -- Women infected with HIV have a much higher risk of getting vulvar, vaginal or perianal cancer than women without HIV, according to a report published in the May issue of Obstetrics & Gynecology.

Denise J. Jamieson, M.D., of the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues compared the incidence of vaginal, vulvar and perianal tumors in 192 HIV-infected women and 88 uninfected women at high risk of HIV in Providence, R.I., over six years.

At the start of the study, only three of the HIV-infected women and none of the uninfected women had vulvar, vaginal or perianal tumors. But the researchers found that 16 out of 189 women with HIV and one of the 88 uninfected women developed these tumors during the study period.

HIV-infected women had an incidence of vulvar, vaginal or perianal intraepithelial neoplasia of 1.96 per 100 person-years, compared to 0.26 per 100 person-years for uninfected women, the researchers report.

"HIV-infected women had more vulvar, vaginal and perianal intraepithelial lesions compared with HIV-uninfected women," the authors write. "Furthermore, the incidence rates were higher than has been found in HIV-infected women in other similar cohorts."

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