Likely Deficient Vitamin D Status Linked to COVID-19 Risk

Risk for testing positive for COVID-19 increased for likely deficient versus likely sufficient vitamin D groups

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FRIDAY, Sept. 4, 2020 (HealthDay News) -- Likely deficient vitamin D status is associated with an increased risk for COVID-19, according to a study published online Sept. 3 in JAMA Network Open.

David O. Meltzer, M.D., Ph.D., from the University of Chicago, and colleagues examined whether the last vitamin D status before COVID-19 testing is associated with COVID-19 test results in a retrospective cohort study. Data were included for 489 patients with a vitamin D level measured in the year preceding COVID-19 testing.

The researchers found that vitamin D status before COVID-19 testing was likely deficient, likely sufficient, and uncertain for 25, 59, and 16 percent of participants, respectively. Seventy-one participants (15 percent) tested positive for COVID-19. Testing positive for COVID-19 was associated with increasing age up to age 50 years, non-White race, and likely deficient versus likely sufficient vitamin D status (relative risks, 1.06, 2.54, and 1.77, respectively) in a multivariable analysis. In the deficient and sufficient vitamin D groups, the predicted COVID-19 rates were 21.6 and 12.2 percent, respectively.

"Understanding whether treating vitamin D deficiency changes COVID-19 risk could be of great importance locally, nationally, and globally," Meltzer said in a statement. "Vitamin D is inexpensive, generally very safe to take, and can be widely scaled."

One author disclosed studying novel compounds for prevention or treatment of viral infections, for which patent protection may be sought.

Abstract/Full Text

Physician’s Briefing Staff

Physician’s Briefing Staff

Published on September 04, 2020

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