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May 2020 Briefing - Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for May 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Globally, Women Less Likely to Develop Heart Disease Than Men

FRIDAY, May 29, 2020 (HealthDay News) -- Women are less likely to have or die from cardiovascular disease than men, according to a study published online May 20 in The Lancet.

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Metformin Recalled Due to Potential Cancer-Causing Chemical

FRIDAY, May 29, 2020 (HealthDay News) -- A recall of the widely used diabetes drug metformin was announced by drug maker Apotex due to possible high levels of N-Nitrosodimethylamine (NDMA), which is believed to cause cancer in people.

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Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of May 25 to 29, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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VA Slashes Use of Hydroxychloroquine to Treat COVID-19 Patients

FRIDAY, May 29, 2020 (HealthDay News) -- The VA health system has stopped nearly all use of hydroxychloroquine to treat COVID-19 patients, Veterans Affairs Secretary Robert Wilkie said at a House hearing on Thursday.

AP News Article

Deferment of Elective Surgeries Due to COVID-19 Will Have Lasting Impact

FRIDAY, May 29, 2020 (HealthDay News) -- At two years after the end of the elective orthopedic surgery deferment related to the COVID-19 pandemic, there will be a cumulative backlog of more than 1 million surgical cases in an optimistic scenario, according to a study published online May 12 in The Journal of Bone and Joint Surgery.

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Positive RT-PCR Findings Seen After COVID-19 Discharge

FRIDAY, May 29, 2020 (HealthDay News) -- Some patients with COVID-19 have positive reverse transcriptase polymerase chain reaction (RT-PCR) results after discharge, according to a research letter published online May 28 in JAMA Network Open.

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1990 to 2017 Saw Increase in Prevalence, Incidence of Psoriasis

FRIDAY, May 29, 2020 (HealthDay News) -- From 1990 to 2017, there were increases in the global prevalence, incidence, and burden of suffering related to psoriasis, according to a report published in the May issue of the International Journal of Dermatology.

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Burden of Severe COVID-19 High in California, Washington State

FRIDAY, May 29, 2020 (HealthDay News) -- For residents of California and Washington with COVID-19, the length of hospital stay and intensive care unit (ICU) admission are high, according to a study published online May 22 in The BMJ.

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Multiple Sclerosis Tied to Higher Risk for CVD, Cerebrovascular Disease

THURSDAY, May 28, 2020 (HealthDay News) -- Multiple sclerosis (MS) is associated with an increased risk for cardiovascular and cerebrovascular disease that is not completely accounted for by traditional vascular risk factors, according to a study published online May 4 in JAMA Neurology.

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CDC: Coronavirus Antibody Tests Still Not Accurate Enough

THURSDAY, May 28, 2020 (HealthDay News) -- Coronavirus antibody test results may not be accurate enough to help guide decisions about whether to allow large groups of people to gather at work, schools, dormitories, correctional facilities, and other locations, the U.S. Centers for Disease Control and Prevention said Wednesday.

CBS News Article
More Information: CDC

Tooth Loss More Prevalent in Adults With Chronic Disease

THURSDAY, May 28, 2020 (HealthDay News) -- Adults with severe chronic disease or with fair or poor general health have a higher prevalence of edentulism and severe tooth loss, according to research published in the May 29 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Parents Facing Higher Levels of Stress During Pandemic

THURSDAY, May 28, 2020 (HealthDay News) -- Individuals, particularly parents, are coping with extreme stress related to the COVID-19 pandemic, according to the results of a survey released May 21 by the American Psychological Association (APA).

Press Release

Disease-Modifying Drug Regimen May Offer Benefit in Heart Failure

THURSDAY, May 28, 2020 (HealthDay News) -- The treatment effects of early comprehensive disease-modifying pharmacological therapy are considerable for patients with heart failure with reduced ejection fraction (HFrEF), according to a study published online May 21 in The Lancet.

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CV Toxicity Tied to Azithromycin and/or Hydroxychloroquine

THURSDAY, May 28, 2020 (HealthDay News) -- Hydroxychloroquine and azithromycin may have a serious adverse impact on the cardiovascular system, according to a research letter published online May 22 in Circulation.

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Links Found Between Leaders of Medical Associations, Industry

THURSDAY, May 28, 2020 (HealthDay News) -- There are extensive financial relationships between leaders of U.S. professional medical associations and industry, according to a study published online May 27 in The BMJ.

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9.5 Percent Uninsured in U.S. From January Through June 2019

WEDNESDAY, May 27, 2020 (HealthDay News) -- A total of 9.5 percent of persons were uninsured from January through June 2019, according to a report published online May 28 by the National Center for Health Statistics.

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Improving Glycemic Control May Also Aid COVID-19 Outcomes

THURSDAY, May 28, 2020 (HealthDay News) -- Insulin infusion helps achieve glycemic targets and may reduce the risk for poor outcomes in patients with hyperglycemia and COVID-19, according to a study published online May 19 in Diabetes Care.

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Spirituality May Have Protective Effect on QOL for Stroke Survivors

THURSDAY, May 28, 2020 (HealthDay News) -- High spirituality among stroke survivors may moderate the association between care partner depressive symptomatology and quality of life (QOL) for survivors and their care partners, according to a study published online May 26 in Circulation: Cardiovascular Quality and Outcomes.

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Parents Struggling to Provide for Families During Pandemic

WEDNESDAY, May 27, 2020 (HealthDay News) -- The COVID-19 pandemic poses risks to children's health, well-being, and development as parents struggle to provide for their families, according to a survey released by the Urban Institute.

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Palliative Care Linked to Fewer Readmissions for Heart Failure

WEDNESDAY, May 27, 2020 (HealthDay News) -- For patients admitted with heart failure, palliative care is associated with fewer readmissions and less mechanical ventilation, according to a study published online May 27 in the Journal of the American Heart Association.

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African-Americans More Likely to Be Hospitalized With COVID-19

WEDNESDAY, May 27, 2020 (HealthDay News) -- African-American patients have an increased likelihood of hospitalization for COVID-19, according to a report published online May 21 in Health Affairs.

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Neuroimaging Features of COVID-19 Are Variable

WEDNESDAY, May 27, 2020 (HealthDay News) -- Neuroimaging features of COVID-19 are variable among patients with acute neurological symptoms but are dominated by acute ischemic infarcts, according to a research letter published online May 21 in Radiology.

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U.K. Patients Hospitalized With COVID-19 Are More Often Male

WEDNESDAY, May 27, 2020 (HealthDay News) -- Patients hospitalized with COVID-19 are more often male and frequently have comorbidities, according to a study published online May 22 in the The BMJ.

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Only One in Four U.S. Hospitals With ICUs Have Tele-ICU Services

WEDNESDAY, May 27, 2020 (HealthDay News) -- In 2018, half of U.S. hospitals had the capacity to conduct telehealth-based outpatient visits, while only one in four had tele-intensive care unit (tele-ICU) capabilities, according to a research letter published online April 30 in the Annals of Internal Medicine.

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Early Informed Lung Cancer Patients Have Greater Survival Rates

WEDNESDAY, May 27, 2020 (HealthDay News) -- Lung cancer patients who are given the opportunity to be informed of their diagnosis have a longer median survival time, according to a study published in the May issue of Psycho-Oncology.

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Primary Care Providers Report More Workplace Burnout, Anxiety

TUESDAY, May 26, 2020 (HealthDay News) -- Primary care providers report more workplace burnout and higher scores for anxiety than other health care professionals, according to a study published in the May issue of the Journal of the American Board of Family Medicine.

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USPSTF: Little Evidence Interventions Prevent Illicit Drug Use in Youth

TUESDAY, May 26, 2020 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) concludes that current evidence is inadequate for assessing the balance of benefits and harms of primary care interventions for preventing illicit drug use among children, adolescents, and young adults. These findings form the basis of a final recommendation statement published in the May 26 issue of the Journal of the American Medical Association.

Evidence Report
Final Recommendation Statement

WHO Suspends Testing of Hydroxychloroquine in COVID-19 Patients

TUESDAY, May 26, 2020 (HealthDay News) -- The World Health Organization has suspended use of the antimalarial drug hydroxychloroquine in a clinical trial of treatments of COVID-19 after a study revealed that patients taking the drug are at increased risk for death and serious heart problems.

AP News Article

New Medicare Benefit Would Limit Insulin Copays to $35 a Month

TUESDAY, May 26, 2020 (HealthDay News) -- Reacting to skyrocketing prices for insulin, the Trump Administration announced on Tuesday a new benefit that would limit Medicare recipients' copays for insulin to a maximum of $35 a month and save them about $446 a year if they have prescription plans that offer the benefit.

AP News Article

High Prevalence of Primary Aldosteronism Observed

TUESDAY, May 26, 2020 (HealthDay News) -- Primary aldosteronism is prevalent and increases in parallel with hypertension severity, according to a study published online May 26 in the Annals of Internal Medicine.

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Lasting Drop Seen in CRC Incidence, Death After Negative Colonoscopy

TUESDAY, May 26, 2020 (HealthDay News) -- Colorectal cancer (CRC) incidence and mortality are reduced for a period of 17.4 years following a single negative screening colonoscopy, according to a study published online May 26 in the Annals of Internal Medicine.

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Environmental Chemical Exposure Tied to Kidney Disease in the U.S.

TUESDAY, May 26, 2020 (HealthDay News) -- Increased exposure to heavy metal lead, cadmium, or volatile organic compounds may be associated with an increased prevalence of chronic kidney disease (CKD), according to a study published online May 22 in the Clinical Journal of the American Society of Nephrology.

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Right Ventricular Dilation Linked to Mortality in COVID-19

TUESDAY, May 26, 2020 (HealthDay News) -- Right ventricular dilation is associated with in-hospital mortality among patients hospitalized with COVID-19, according to a study published online May 15 in JACC: Cardiovascular Imaging.

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Remdesivir Beats Placebo for Time to COVID-19 Recovery

TUESDAY, May 26, 2020 (HealthDay News) -- For adults hospitalized with COVID-19 with lower respiratory tract infection, time to recovery is shorter with remdesivir than placebo, according to a study published online May 22 in the New England Journal of Medicine.

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Hydroxychloroquine Plus Macrolides No Benefit in COVID-19

TUESDAY, May 26, 2020 (HealthDay News) -- For patients with COVID-19 requiring hospitalization, there is no evidence of benefit for use of hydroxychloroquine or chloroquine with or without a macrolide, according to a study published online May 22 in The Lancet.

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Adenovirus Type-5 Vectored COVID-19 Vaccine Shows Promise

TUESDAY, May 26, 2020 (HealthDay News) -- A recombinant adenovirus type-5 (Ad5) vectored COVID-19 vaccine is safe, tolerable, and immunogenic, according to a study published online May 22 in The Lancet.

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Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of May 18 to 22, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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U.S. Offers $1.2 Billion to Drug Company for COVID-19 Vaccine Research

FRIDAY, May 22, 2020 (HealthDay News) -- The U.S. Department of Health and Human Services said Thursday it would provide up to $1.2 billion to AstraZeneca to develop a potential COVID-19 vaccine from a lab in Oxford, England.

The New York Times Article

CDC: COVID-19 Not Spread Easily From Contaminated Surfaces

FRIDAY, May 22, 2020 (HealthDay News) -- COVID-19 spreads swiftly between people but is not easily caught from contaminated surfaces, according to updated information from the U.S. Centers for Disease Control and Prevention.

Washington Post Article
More Information: CDC

U.S. Government Seeks Deal With Private Industry to Boost Supply of Medical Equipment

FRIDAY, May 22, 2020 (HealthDay News) -- In an effort to prevent the United States from again struggling to have enough medical supplies in a pandemic, the federal government is seeking to make a five-year deal with U.S. manufacturers.

AP News Article
Johns Hopkins University

SARS-CoV-2 Antibodies Detected in 4.65 Percent in Los Angeles County

FRIDAY, May 22, 2020 (HealthDay News) -- In recent serologic tests, the weighted prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies was 4.65 percent among adult residents of Los Angeles County, California, after adjustment for test sensitivity and specificity, according to a research letter published online May 18 in the Journal of the American Medical Association.

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Age, Sex, History of Diabetes Predict Intubation in COVID-19

FRIDAY, May 22, 2020 (HealthDay News) -- Older age, male sex, and history of diabetes are factors predictive of intubation among hospitalized patients with COVID-19, while age and body mass index are associated with time to extubation, according to a study published online May 19 in Otolaryngology-Head and Neck Surgery.

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Incidence of AMI Hospitalization Down During COVID-19

FRIDAY, May 22, 2020 (HealthDay News) -- In Northern California, the incidence of hospitalization for acute myocardial infarction decreased during the COVID-19 pandemic period, according to a letter to the editor published online May 19 in the New England Journal of Medicine.

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ED Chest X-Ray Score Predicts COVID-19 Outcomes in Adults <50

FRIDAY, May 22, 2020 (HealthDay News) -- A chest X-ray (CXR) severity score can predict outcomes among young and middle-aged adults with COVID-19 on presentation to the emergency department, according to a study published online May 14 in Radiology.

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Cardiac Decompensation Seen in Children Following COVID-19

FRIDAY, May 22, 2020 (HealthDay News) -- Children may experience acute cardiac decompensation due to a severe inflammatory state (multisystem inflammatory syndrome in children or MIS-C) following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a study published online May 17 in Circulation.

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Biomechanical Footwear May Aid Knee Osteoarthritis Outcomes

FRIDAY, May 22, 2020 (HealthDay News) -- Use of biomechanical footwear is associated with an improvement in pain among patients with knee osteoarthritis at 24 weeks of follow-up, although the improvements are of uncertain clinical importance, according to a study published in the May 12 issue of the Journal of the American Medical Association.

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One-Year Mortality High Following ED Visit for Overdose

THURSDAY, May 21, 2020 (HealthDay News) -- Emergency department patients with nonfatal opioid or sedative/hypnotic drug overdose have exceptionally high risks for death in the following year, according to a study published online May 7 in the American Journal of Preventive Medicine.

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Convalescent Plasma Trial for COVID-19 Patients Underway at NYU Langone

THURSDAY, May 21, 2020 (HealthDay News) -- Researchers at the NYU Grossman School of Medicine are conducting a phase II clinical trial to determine the efficacy of convalescent plasma in hospitalized patients with COVID-19. Corita R. Grudzen, M.D., vice chair for research in the Ronald O. Perelman Department of Emergency Medicine at NYU Langone Health, wrote the study protocol and recently spoke with HealthDay Live! about the trial.

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NYU Langone Health Press Release

CDC: Live Poultry Linked to Salmonella Cases in 28 States

THURSDAY, May 21, 2020 (HealthDay News) -- Live poultry, such as chicks and ducklings, in backyard flocks have caused Salmonella infections that have sickened 97 people in 28 states, the U.S. Centers for Disease Control and Prevention said Wednesday.

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Factors Linked to COVID-19 In-Hospital Mortality ID'd in NYC

THURSDAY, May 21, 2020 (HealthDay News) -- Factors associated with in-hospital mortality include older age, chronic cardiac disease, and chronic pulmonary disease in a cohort of hospitalized patients with COVID-19 in New York City, according to a study published online May 19 in The Lancet.

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Mobile Platform Useful for Treating Depression, Anxiety

THURSDAY, May 21, 2020 (HealthDay News) -- A coach-supported platform composed of a suite of apps is effective for treating depression and anxiety among primary care patients, according to a study published online May 20 in JAMA Psychiatry.

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Melanoma Risk From Biologic Therapy Remains Uncertain

THURSDAY, May 21, 2020 (HealthDay News) -- Clinically important increases in melanoma risk in patients treated with biologic therapy for common inflammatory diseases cannot be ruled out based on current evidence, according to a review published online May 20 in JAMA Dermatology.

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Deaths From Alcohol, Drugs, Suicide Topped 150,000 in 2018

THURSDAY, May 21, 2020 (HealthDay News) -- In 2018, opioid overdose deaths declined, but deaths involving alcohol, suicide, synthetic opioids, and other psychostimulants rose, according to a brief released May 21 by the Trust for America's Health and the Well Being Trust.

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Asthma Tied to Longer COVID-19 Intubation Time

THURSDAY, May 21, 2020 (HealthDay News) -- Among COVID-19 patients who develop severe respiratory symptoms requiring intubation, asthma is associated with a significantly longer intubation time, according to a study published online May 14 in the Journal of Allergy and Clinical Immunology: In Practice.

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ACR Updates Guideline for Management of Gout

THURSDAY, May 21, 2020 (HealthDay News) -- In an updated American College of Rheumatology guideline, published online May 11 in Arthritis Care & Research, recommendations are presented for the management of gout.

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Clinical Performance of SARS-COV-2 Antibody Tests Varies

THURSDAY, May 21, 2020 (HealthDay News) -- The diagnostic specificity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serologic assays varies, and sensitivity is poor during the first 14 days of symptoms, according to a study published online May 13 in Clinical Chemistry.

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Sales of Johnson's Baby Powder Halted in U.S., Canada

WEDNESDAY, May 20, 2020 (HealthDay News) -- Lawsuits claiming that talc-based Johnson's Baby Powder has caused cancer have led to a plunge in sales in the United States and Canada, so Johnson & Johnson said Tuesday it is ending sales of the product in those two countries.

AP News Article

Some Children With COVID-19 Require Admission, PICU Care

WEDNESDAY, May 20, 2020 (HealthDay News) -- Some children with COVID-19 require admission and intensive care, according to a study published online May 11 in The Journal of Pediatrics.

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High BMI in Childhood May Up Risk for Bladder Cancer as Adult

WEDNESDAY, May 20, 2020 (HealthDay News) -- Childhood body mass index (BMI) is positively associated, while childhood height is inversely associated, with the risk for bladder cancer (BC) in adulthood, according to a study published online May 19 in the Annals of Human Biology.

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Multiple Genes Predispose Black Women to Breast Cancer

WEDNESDAY, May 20, 2020 (HealthDay News) -- Multiple genes predispose African-American (AA) women to breast cancer, including BRCA1, BRCA2, and PALB2, according to a study published online May 19 in the Journal of the National Cancer Institute.

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Editorial

Sex Differences ID'd in Prescription of Cardiovascular Meds

WEDNESDAY, May 20, 2020 (HealthDay News) -- For patients at high risk for or with established cardiovascular disease in primary care, sex differences exist in the prescription of cardiovascular medications, according to a review published online May 20 in the Journal of the American Heart Association.

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Age, CRP Up Risk for Mortality in Diabetes With COVID-19

WEDNESDAY, May 20, 2020 (HealthDay News) -- For patients with diabetes and COVID-19, risk factors for mortality include older age and elevated C-reactive protein, and insulin usage is associated with poor prognosis, according to a study published online May 14 in Diabetes Care.

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Excessive Drinking Seen in Some Patients With Chronic Conditions

WEDNESDAY, May 20, 2020 (HealthDay News) -- Among those reporting alcohol use, patients with certain common medical conditions are more likely to report excessive drinking, according to a study published online May 13 in JAMA Network Open.

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Global Practice Guidelines Issued by International Society of Hypertension

WEDNESDAY, May 20, 2020 (HealthDay News) -- In International Society of Hypertension practice guidelines, published in the June issues of Hypertension and the Journal of Hypertension, recommendations are presented for the management of hypertension in adults aged 18 years and older.

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Obesity Tied to Increased Risk for Progression to Severe COVID-19

TUESDAY, May 19, 2020 (HealthDay News) -- Obesity is associated with a significantly increased risk for progression to severe COVID-19, according to a study published online May 14 in Diabetes Care.

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Mental Health Symptoms Up for Medics Dealing With COVID-19

TUESDAY, May 19, 2020 (HealthDay News) -- The scores for mental health symptoms in medical personnel responding to COVID-19 pneumonia are generally higher than the norm in China, according to a study published online May 19 in PLOS ONE.

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Factors ID'd for Positive SARS-CoV-2 Test Result in Primary Care

TUESDAY, May 19, 2020 (HealthDay News) -- Sociodemographic factors associated with the risk for a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test result include deprivation, population density, and ethnicity, according to a study published online May 15 in The Lancet Infectious Diseases.

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Higher Intake of Whole-Fat Dairy May Cut Metabolic Syndrome Risk

TUESDAY, May 19, 2020 (HealthDay News) -- Higher intake of whole-fat dairy products is associated with a lower prevalence of metabolic syndrome (MetS) as well as hypertension and diabetes, according to a study published online May 18 in BMJ Open Diabetes Research & Care.

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Hydroxychloroquine Does Not Improve COVID-19 Pneumonia Outcomes

TUESDAY, May 19, 2020 (HealthDay News) -- Hydroxychloroquine does not improve outcomes in COVID-19, according to two studies published online May 14 in The BMJ.

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Corticosteroids for IBD May Up Risk for Severe COVID-19

TUESDAY, May 19, 2020 (HealthDay News) -- For patients with inflammatory bowel disease (IBD) and COVID-19, risk factors for severe disease include increasing age, comorbidities, and systemic corticosteroids, according to a study published online May 18 in Gastroenterology.

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Spending on Primary Care Continues to Lag in the U.S.

TUESDAY, May 19, 2020 (HealthDay News) -- Spending on inpatient services, specialty care, and prescriptions together accounted for about two-thirds of the increase in total U.S. health care spending from 2002 to 2016, according to a research letter published online May 18 in JAMA Internal Medicine.

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Burnout Comparable Between Millennial, Gen X Residents, Fellows

TUESDAY, May 19, 2020 (HealthDay News) -- Millennial and Generation X medical residents and fellows experience similar rates of burnout and have similar levels of empathy, according to a study published online May 5 in Academic Psychiatry.

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Higher Burden of Cardiovascular Risk Tied to Cognitive Decline

TUESDAY, May 19, 2020 (HealthDay News) -- Higher cardiovascular risk burden is associated with cognitive decline and neurodegeneration, according to a study published in the May 26 issue of the Journal of the American College of Cardiology.

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Osteoporotic Fracture Risk Lower for DOAC Than Warfarin in A-Fib

MONDAY, May 18, 2020 (HealthDay News) -- For patients with atrial fibrillation (AF), the risk for osteoporotic fracture appears to be lower with direct oral anticoagulant (DOAC) use compared with warfarin use, according to a study published online May 19 in the Annals of Internal Medicine.

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Fruit-, Veggie-Rich Diet May Soon Lower Markers for Cardiac Injury

MONDAY, May 18, 2020 (HealthDay News) -- For middle-aged adults without preexisting cardiovascular disease, eating a diet rich in fruits and vegetables over eight weeks is associated with lower levels of markers for subclinical cardiac damage and strain, according to a study published online May 19 in the Annals of Internal Medicine.

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Social Distancing Policies Reduced COVID-19 Growth Rate

MONDAY, May 18, 2020 (HealthDay News) -- The impact of four widely adopted social distancing policies reduced the daily growth rate of COVID-19 across U.S. counties, according to a report published online May 14 in Health Affairs.

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Experimental COVID-19 Vaccine Appears Safe, Triggers Immune Response

MONDAY, May 18, 2020 (HealthDay News) -- An experimental vaccine against COVID-19 appears to be safe and to trigger an immune response, according to results of the first human clinical trial of a COVID-19 vaccine.

The New York Times Article

Guidance Issued for Osteoporosis Management During COVID-19

FRIDAY, May 15, 2020 (HealthDay News) -- In a joint guidance document issued by the American Society for Bone and Mineral Research, American Association of Clinical Endocrinologists, Endocrine Society, European Calcified Tissue Society, and National Osteoporosis Foundation, recommendations are presented for the management of osteoporosis during the COVID-19 pandemic.

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Co-Occurring Visual Impairment, Dementia Heighten Disability Risk

MONDAY, May 18, 2020 (HealthDay News) -- Older adults with both dementia and self-reported visual impairment (VI) may be at higher risk for disability than adults with only one of these conditions, according to a study published online May 14 in JAMA Ophthalmology.

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Hydroxychloroquine No Aid for COVID-19-Related Mortality

MONDAY, May 18, 2020 (HealthDay News) -- Treating hospitalized COVID-19 patients with hydroxychloroquine, azithromycin, or both is not associated with improvements in in-hospital mortality, according to a study published online May 11 in the Journal of the American Medical Association.

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Convalescent Plasma Appears Promising for Severe COVID-19

MONDAY, May 18, 2020 (HealthDay News) -- Administration of convalescent plasma seems safe and results in improvement in clinical status for patients with severe or life-threatening COVID-19, according to a study not yet peer reviewed and posted on medRxiv.org.

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Most Physicians Have Seen False-Negative COVID-19 Test Results

MONDAY, May 18, 2020 (HealthDay News) -- Most physicians believe they have seen false-negative results for a COVID-19 diagnostic test, according to the results of a recent survey.

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Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of May 11 to 15, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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NIH Launches Trial of Hydroxychloroquine, Azithromycin for COVID-19

FRIDAY, May 15, 2020 (HealthDay News) -- The National Institute of Allergy and Infectious Diseases (NIAID) announced it is sponsoring a phase 2b clinical trial to evaluate the efficacy and safety of hydroxychloroquine and azithromycin in preventing hospitalization and death from COVID-19.

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FDA: Abbott Rapid COVID-19 Test Could Miss Infections

FRIDAY, May 15, 2020 (HealthDay News) -- A rapid COVID-19 test being used across the United States could miss infections, the U.S. Food and Drug Administration said Thursday.

More Information: FDA
The New York Times Article

COVID-19 Cases Increased More Rapidly With No Stay-at-Home Order in Iowa

FRIDAY, May 15, 2020 (HealthDay News) -- COVID-19 cases increased more quickly in border counties in Iowa and more slowly in border counties in Illinois following enactment of a stay-at-home order in Illinois, according to a study published online May 15 in JAMA Network Open.

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NIH: Large-Scale Testing of Some COVID-19 Vaccines Could Start in July

FRIDAY, May 15, 2020 (HealthDay News) -- A number of COVID-19 vaccines under development "look pretty promising" and one or two could be ready for large-scale testing by July, the director of the U.S. National Institutes of Health says.

AP News Article

ACP Advises Against Chloroquine, Hydroxychloroquine for COVID-19

FRIDAY, May 15, 2020 (HealthDay News) -- In a special article from the American College of Physicians (ACP), published online May 13 in the Annals of Internal Medicine, practice points are presented to guide the use of chloroquine or hydroxychloroquine in the setting of COVID-19.

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T2DM Linked to Worse Cognitive Performance After Stroke

FRIDAY, May 15, 2020 (HealthDay News) -- In a stroke population, type 2 diabetes (T2D), but not impaired fasting glucose, is associated with worse cognitive performance, according to a study published online May 14 in Stroke.

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Intensive Blood Pressure Control Tied to Lower Atrial Fibrillation Risk

FRIDAY, May 15, 2020 (HealthDay News) -- Intensive blood pressure (BP) control can lower the risk for atrial fibrillation (AF) in patients with hypertension at high risk for cardiovascular disease, according to a study published online May 4 in Hypertension.

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Regular Aspirin Use Tied to Lower Risk for Digestive Tract Cancers

FRIDAY, May 15, 2020 (HealthDay News) -- Regular aspirin use is associated with a lower risk for colorectal and other digestive tract cancers, according to a review published in the May 1 issue of the Annals of Oncology.

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Any Weight Loss Before Bariatric Surgery May Cut 30-Day Mortality

THURSDAY, May 14, 2020 (HealthDay News) -- Even moderate weight loss before bariatric surgery is associated with a lower risk for 30-day mortality, according to a study published online May 14 in JAMA Network Open.

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Opt-Out Universal Hep C Screening in Emergency Dept Is Useful

THURSDAY, May 14, 2020 (HealthDay News) -- Emergency department opt-out universal hepatitis C virus (HCV) screening can identify a large number of unrecognized HCV infections, including among those born after 1965, according to research published in the May 15 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Abnormalities Detected on Brain MRI of COVID-19 Patients in ICU

THURSDAY, May 14, 2020 (HealthDay News) -- Among patients with COVID-19 pneumonia in the intensive care unit (ICU) with neurological symptoms, 44 percent of those undergoing magnetic resonance imaging (MRI) have acute findings, according to a study published online May 8 in Radiology.

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Poll: One in Seven Older Adults Report Food Insecurity

THURSDAY, May 14, 2020 (HealthDay News) -- One in seven adults ages 50 to 80 years say they experienced household food insecurity in the past year (before the COVID-19 pandemic), according to a report published online May 11 based on the results of the University of Michigan National Poll on Healthy Aging.

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COVID-19 Fatality Rate High for Heart Transplant Recipients

THURSDAY, May 14, 2020 (HealthDay News) -- Heart transplant (HT) recipients with COVID-19 infection have a case fatality rate of 25 percent, according to a study published online May 13 in JAMA Cardiology.

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Meta-Analysis Links Smoking to COVID-19 Disease Progression

THURSDAY, May 14, 2020 (HealthDay News) -- Smokers have an increased likelihood of COVID-19 disease progression, according to research published online May 13 in Nicotine & Tobacco Research.

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Improvements Seen in Some Cognitive Domains With Aerobic Exercise

THURSDAY, May 14, 2020 (HealthDay News) -- A six-month aerobic exercise intervention is associated with improvements in cognitive domains and cerebrovascular regulation among middle-aged and older adults, according to a study published online May 13 in Neurology.

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Cannabis Smoking May Increase Risk for Fungal Infection

THURSDAY, May 14, 2020 (HealthDay News) -- The likelihood of having a fungal infection was increased in association with cannabis use in 2016, according to a study published online May 13 in Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention.

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Risk for Inflammatory Bowel Disease, Celiac Disease Linked

THURSDAY, May 14, 2020 (HealthDay News) -- Patients with celiac disease have an increased risk for inflammatory bowel disease (IBD) and vice versa, according to research published online May 13 in Gastroenterology.

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Bowel Abnormalities Described in Inpatients With COVID-19

THURSDAY, May 14, 2020 (HealthDay News) -- Bowel abnormalities have been identified on abdominal imaging of some inpatients with COVID-19, according to a study published online May 11 in Radiology.

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Sickness Presenteeism Common With Influenza-Like Illness

WEDNESDAY, May 13, 2020 (HealthDay News) -- Most health care workers (HCWs) and non-HCWs continue to work when sick with influenza-like illness (ILI), according to a study published online May 13 in PLOS ONE.

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Plan in Place to Up Production of Prefilled Syringes for Future COVID-19 Vaccine

WEDNESDAY, May 13, 2020 (HealthDay News) -- A deal for hundreds of millions of syringes that could be used to quickly administer a possible vaccine against COVID-19 has been reached between the U.S. government and a private company.

NBC News Article

Live Biotherapeutic Promising for Prevention of Bacterial Vaginosis

WEDNESDAY, May 13, 2020 (HealthDay News) -- For women with bacterial vaginosis, Lactobacillus crispatus CTV-05 (Lactin-V) after vaginal metronidazole results in a lower incidence of recurrence at 12 weeks, according to a study published in the May 14 issue of the New England Journal of Medicine.

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Sugar-Sweetened Beverages May Increase Risk for CVD in Women

WEDNESDAY, May 13, 2020 (HealthDay News) -- Sugar-sweetened beverage (SSB) consumption is associated with an increased risk for cardiovascular disease (CVD), revascularization, and stroke among women, according to a study published online May 13 in the Journal of the American Heart Association.

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Pulmonary Rehab Associated With Lower COPD Mortality

WEDNESDAY, May 13, 2020 (HealthDay News) -- Initiation of pulmonary rehabilitation within three months of hospital discharge for chronic obstructive pulmonary disease (COPD) is significantly associated with a lower risk for mortality at one year for Medicare beneficiaries, according to a study published in the May 12 issue of the Journal of the American Medical Association.

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Editorial (subscription or payment may be required)

Burden of Osteoarthritis Increasing in Most Countries

WEDNESDAY, May 13, 2020 (HealthDay News) -- The burden of osteoarthritis (OA) is increasing in most countries, according to a study published online May 12 in Annals of the Rheumatic Diseases.

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Experts Discuss Strategy for Bariatric Surgery During COVID-19

WEDNESDAY, May 13, 2020 (HealthDay News) -- In a personal view article, published online May 7 in The Lancet Diabetes & Endocrinology, recommendations are presented for the management of bariatric and metabolic surgery patients during the COVID-19 pandemic.

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PM2.5 Linked to Later Mortality in Certain Pediatric, AYA Cancers

WEDNESDAY, May 13, 2020 (HealthDay News) -- For pediatric and adolescent and young adult (AYA) patients with specific cancers, continued exposure to fine particulate matter (PM2.5) is associated with later mortality, according to a study published online May 13 in Cancer, Epidemiology, Biomarkers & Prevention.

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Grip Strength May Help ID Type 2 Diabetes Risk in Healthy Adults

WEDNESDAY, May 13, 2020 (HealthDay News) -- Grip strength may predict type 2 diabetes risk in healthy adults, according to a study recently published in the American Journal of Preventive Medicine.

Abstract/Full Text

Children of Mothers With Mental Illness Less Likely to Receive Vaccines

WEDNESDAY, May 13, 2020 (HealthDay News) -- Children whose mothers have mental illness are significantly less likely to receive vaccinations through age 5 years, according to a study published online April 24 in the European Journal of Epidemiology.

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USPSTF Urges Behavioral Counseling for Those With CVD Risk

TUESDAY, May 12, 2020 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends behavioral counseling to promote a healthy lifestyle for adults at risk for cardiovascular disease. These recommendations form the basis of a draft recommendation statement published online May 12 by the USPSTF.

Draft Evidence Review
Draft Recommendation Statement
Comment on Recommendation Statement

Risk Score May Predict Critical Illness at COVID-19 Admission

TUESDAY, May 12, 2020 (HealthDay News) -- A risk score based on 10 factors can predict the risk for developing critical illness at COVID-19 admission, according to a study published online May 12 in JAMA Internal Medicine.

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Doctors Without Borders Team Sent to Navajo Nation to Fight COVID-19

TUESDAY, May 12, 2020 (HealthDay News) -- Doctors Without Borders has sent a nine-person team to the Navajo Nation in the Southwestern United States as it struggles with a COVID-19 crisis.

CBS News Article

Olfactory Dysfunction Most Often Occurs by Third Day of COVID-19

TUESDAY, May 12, 2020 (HealthDay News) -- Olfactory dysfunction (OD) occurs commonly, severely, and early in COVID-19 infection, according to a study published online May 5 in Otolaryngology-Head and Neck Surgery.

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Gap in Rural, Urban CVD Deaths Grew From 1999 to 2017

TUESDAY, May 12, 2020 (HealthDay News) -- The gap between rural and urban areas grew for cardiovascular disease age-adjusted mortality rates (AAMRs) between 1999 and 2017, according to a research letter published in the May 12 issue of the Journal of the American Medical Association.

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Crude Link ID'd for Vitamin D Levels, COVID-19 Cases, Death

TUESDAY, May 12, 2020 (HealthDay News) -- There is a crude correlation between vitamin D levels and the number of COVID-19 cases and COVID-19 mortality, according to a study published online May 6 in Aging Clinical and Experimental Research.

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Long-Term Flavonoid Intake Tied to Lower Alzheimer Risk

TUESDAY, May 12, 2020 (HealthDay News) -- Higher long-term dietary intake of flavonoids is associated with lower risks for Alzheimer disease and related dementias (ADRD) in U.S. adults, according to a study published online April 22 in the American Journal of Clinical Nutrition.

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For Those With Heart Failure, ACE2 Concentrations Up in Men

TUESDAY, May 12, 2020 (HealthDay News) -- Among patients with heart failure, men have higher plasma concentrations of angiotensin-converting enzyme 2 (ACE2), while neither use of angiotensin-converting enzyme (ACE) inhibitors nor angiotensin receptor blockers (ARBs) are associated with increased plasma ACE2 concentrations, according to a study published online May 10 in the European Heart Journal.

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Thigh Circumference Tied to Hypertension Risk

TUESDAY, May 12, 2020 (HealthDay News) -- Large thigh circumference is associated with a lower risk for hypertension in overweight and obese individuals, according to a study published in the April issue of Endocrine Connections.

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Bone Health Declining in U.S. Adults With and Without Prediabetes

TUESDAY, May 12, 2020 (HealthDay News) -- The bone health of adults older than 40 years of age is declining for individuals both with normal glucose regulation and prediabetes, according to a study recently published in Diabetes Care.

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Residual Shunt After PFO Closure Linked to Higher Risk for Stroke

MONDAY, May 11, 2020 (HealthDay News) -- The presence of a residual shunt after patent foramen ovale (PFO) closure is associated with an increased risk for recurrent stroke or transient ischemic attack (TIA), according to a study published online May 12 in the Annals of Internal Medicine.

Abstract/Full Text
Editorial

Hydroxychloroquine Has No Impact on Outcomes in COVID-19

MONDAY, May 11, 2020 (HealthDay News) -- Hydroxychloroquine is not associated with an increased or decreased risk for intubation or death among patients with COVID-19 admitted to the hospital, according to a study published online May 7 in the New England Journal of Medicine.

Abstract/Full Text
Editorial

Acupuncture Beneficial for Postprandial Distress Syndrome

MONDAY, May 11, 2020 (HealthDay News) -- Acupuncture results in an increased response rate and elimination rate for all the cardinal symptoms in patients with postprandial distress syndrome (PDS), according to a study published online May 12 in the Annals of Internal Medicine.

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Cardiorespiratory Fitness Aids Mortality Prediction

MONDAY, May 11, 2020 (HealthDay News) -- Cardiorespiratory fitness (CRF) improves mortality risk prediction beyond conventional risk factors, according to a study published in the May issue of Mayo Clinic Proceedings.

Abstract/Full Text
Editorial

SARS-CoV-2 Spreads Rapidly Through Skilled Nursing Facilities

MONDAY, May 11, 2020 (HealthDay News) -- Rapid and widespread transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur in skilled nursing facilities, according to a study published online April 24 in the New England Journal of Medicine.

Abstract/Full Text
Editorial

Epidemic Growth of COVID-19 Not Linked to Latitude, Temperature

MONDAY, May 11, 2020 (HealthDay News) -- For COVID-19, epidemic growth is not associated with latitude and temperature or with absolute humidity, according to a study published online May 8 in CMAJ, the journal of the Canadian Medical Association.

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Significant Reductions Seen in Breast Cancer Death With Screening

MONDAY, May 11, 2020 (HealthDay News) -- Women participating in mammography screening have a significant reduction in the risk for dying of breast cancer and in the rate of advanced breast cancers, according to a study published online May 11 in Cancer.

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IBD Not Tied to Female Genital Tract Malignancies

MONDAY, May 11, 2020 (HealthDay News) -- Inflammatory bowel disease (IBD) patients do not have a higher risk for female genital tract malignancies, according to a study recently published in Digestive and Liver Disease.

Abstract/Full Text
Editorial

ACR Issues Statement on Return of Routine Radiology Services

MONDAY, May 11, 2020 (HealthDay News) -- In an American College of Radiology statement, published online May 6 in the Journal of the American College of Radiology, recommendations are presented for re-engagement of routine radiology care during the COVID-19 pandemic.

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Long-Term Physical Activity Not Tied to Knee Arthritis

FRIDAY, May 8, 2020 (HealthDay News) -- There is no association between long-term strenuous physical activity participation and incident radiographic knee osteoarthritis (KOA), according to a study published online May 4 in JAMA Network Open.

Abstract/Full Text

Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of May 4 to 8, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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FDA Slashes Number of Approved Chinese Makers of N95 Masks

FRIDAY, May 8, 2020 (HealthDay News) -- The number of mask makers in China approved to make N95-type masks for U.S. health care workers was slashed from 80 to 14 by the U.S. Food and Drug Administration on Thursday.

MarketWatch Article

Most Jurisdictions Report COVID-19 in Correctional Facilities

FRIDAY, May 8, 2020 (HealthDay News) -- At least one laboratory-confirmed COVID-19 case has been reported in correctional and detention facilities in 86 percent of 54 state and territorial health department jurisdictions, according to research published in the May 6 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Symptomatic COVID-19 Infection Fatality Rate 1.3 Percent in U.S.

FRIDAY, May 8, 2020 (HealthDay News) -- The overall infection fatality rate (IFR) among symptomatic COVID-19 cases (IFR-S) in the United States is estimated at 1.3 percent, according to a report published online May 7 in Health Affairs.

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CDC: Prevalence of Hypertension Higher in Rural Versus Urban Areas

FRIDAY, May 8, 2020 (HealthDay News) -- The prevalence of hypertension varies across states and is higher in rural versus urban areas, according to research published in the May 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Asthma, COPD Medication Adherence Up During Pandemic

FRIDAY, May 8, 2020 (HealthDay News) -- Medication adherence for asthma and chronic obstructive pulmonary disease (COPD) has increased during the COVID-19 pandemic, according to a study published online May 3 in the Journal of Allergy and Clinical Immunology: In Practice.

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Risk for SARS-CoV-2 Lower for Prostate Cancer Patients on ADT

FRIDAY, May 8, 2020 (HealthDay News) -- Among prostate cancer patients, those receiving androgen-deprivation therapy (ADT) versus other treatments have a lower risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published online May 6 in the Annals of Oncology.

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Deaths of Despair Likely to Increase During Pandemic

FRIDAY, May 8, 2020 (HealthDay News) -- Up to 75,000 more people could die from drug or alcohol misuse and suicide during the COVID-19 pandemic, according to a report released May 8 by the Well Being Trust (WBT) and the Robert Graham Center for Policy Studies in Family Medicine and Primary Care.

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SARS-CoV-2 Identified in Semen of Men With COVID-19

FRIDAY, May 8, 2020 (HealthDay News) -- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is present in the semen of some patients with COVID-19, including recovering patients, according to a study published online May 7 in JAMA Network Open.

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Incidence of Psych Morbidity Up With Spinal Cord Injury

FRIDAY, May 8, 2020 (HealthDay News) -- Adults with traumatic spinal cord injuries (SCIs) have an increased incidence of psychological morbidities and multimorbidity, according to a study published in the May issue of Mayo Clinic Proceedings.

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ACE Inhibitor/ARB Use Not Tied to COVID-19 Test Positivity

FRIDAY, May 8, 2020 (HealthDay News) -- Angiotensin-converting enzyme inhibitor (ACEI) and/or angiotensin receptor blocker (ARB) use is not associated with COVID-19 test positivity, according to a study published online May 5 in JAMA Cardiology.

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Editorial

Death and Disability From Stroke Down in United Kingdom

FRIDAY, May 8, 2020 (HealthDay News) -- The risk for death and disability after a stroke fell significantly between 2000 and 2015 in the United Kingdom, according to a study recently published in PLOS Medicine.

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Doubt Cast on Notion That New Strain of COVID-19 Is More Infectious

THURSDAY, May 7, 2020 (HealthDay News) -- A new study suggesting that COVID-19 has mutated to become even more infectious should be viewed with skepticism, former U.S. Food and Drug Administration head Scott Gottlieb, M.D., said Wednesday.

CNBC Article

SES Mediates Racial Differences in Kidney Transplant Listing

THURSDAY, May 7, 2020 (HealthDay News) -- Among patients with kidney failure, accounting for socioeconomic status (SES) and comorbidity attenuates racial disparities in listing for, but not receipt of, kidney transplant, according to a study published online May 7 in the Clinical Journal of the American Society of Nephrology.

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Health Insurance Coverage Disruption Impedes Cancer Care

THURSDAY, May 7, 2020 (HealthDay News) -- Disruptions in health insurance coverage are common and are associated with poorer cancer care and survival, according to a review published online April 27 in the Journal of the National Cancer Institute.

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RHB-105 Effective for Eradication of Helicobacter pylori in Adults

THURSDAY, May 7, 2020 (HealthDay News) -- A novel rifabutin-based triple therapy (RHB-105) is effective for eradication of Helicobacter pylori, with eradication rates unaffected by resistance to clarithromycin or metronidazole, according to a study published online May 5 in the Annals of Internal Medicine.

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Anticoagulation May Improve Outcomes in COVID-19 Patients

THURSDAY, May 7, 2020 (HealthDay News) -- For patients hospitalized with COVID-19, systematic anticoagulation (AC) may be associated with improved outcomes, according to a research letter published online May 6 in the Journal of the American College of Cardiology.

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Cardio-Obstetrics Team Key to Managing CVD in Pregnancy

THURSDAY, May 7, 2020 (HealthDay News) -- A cardio-obstetrics team is essential for management of cardiovascular disease during pregnancy, according to an American Heart Association scientific statement published online May 4 in Circulation.

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GI Symptoms Seen in Less Than 10 Percent of COVID-19 Patients

THURSDAY, May 7, 2020 (HealthDay News) -- Gastrointestinal (GI) symptoms are seen in less than 10 percent of patients with COVID-19, according to a meta-analysis published online May 4 in Gastroenterology.

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Organic Nitrates May Not Aid Bone Health in Postmenopausal Women

THURSDAY, May 7, 2020 (HealthDay News) -- Organic nitrates do not have clinically relevant effects on bone mineral density (BMD) or bone turnover in postmenopausal women, according to a study published online May 5 in the Journal of Bone and Mineral Research.

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Link Found Between Body Size in Childhood, Later Life Disease

THURSDAY, May 7, 2020 (HealthDay News) -- Large adult body size contributes to the association between genetically predicted larger body size in childhood and coronary artery disease and type 2 diabetes later in life, according to a study published online May 6 in The BMJ.

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Human Trials of Experimental COVID-19 Vaccine Begin in U.S.

WEDNESDAY, May 6, 2020 (HealthDay News) -- Human trials on an experimental COVID-19 vaccine began in the United States on Monday, Pfizer and the German pharmaceutical company BioNTech said.

The New York Times Article

New Coronavirus Strain More Contagious, Scientists Say

WEDNESDAY, May 6, 2020 (HealthDay News) -- A new, mutated strain of the coronavirus that causes COVID-19 has become dominant and appears to be more contagious than the strain that spread during the early stages of the pandemic, scientists report.

Los Angeles Times Article

Yoga + Medical Care Better for Episodic Migraines

WEDNESDAY, May 6, 2020 (HealthDay News) -- Yoga plus medical care is better than medical therapy alone for the treatment of episodic migraines, according to a study published online May 6 in Neurology.

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Health Care Workers at Risk From Mental Burden of COVID-19

WEDNESDAY, May 6, 2020 (HealthDay News) -- Health care workers and younger people have an increased risk for a psychological impact from COVID-19, according to a study published online April 14 in Psychology, Health & Medicine.

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HIV+ Men Are Not Receiving STD Testing, Prevention Services

WEDNESDAY, May 6, 2020 (HealthDay News) -- Many sexually active men who have sex with men (MSM) do not receive recommended prevention services and sexually transmitted disease (STD) testing when receiving care for HIV infection, according to a research letter published online May 5 in the Annals of Internal Medicine.

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Guideline Issued for Nonsevere, Severe COVID-19 Therapy

WEDNESDAY, May 6, 2020 (HealthDay News) -- In an evidence-based guideline developed by an international team of physicians, pharmacists, researchers, and patients, published online April 29 in CMAJ, the journal of the Canadian Medical Association, recommendations are presented for the treatment of COVID-19.

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Well-Controlled Blood Glucose May Improve COVID-19 Outcomes

WEDNESDAY, May 6, 2020 (HealthDay News) -- For patients with COVID-19 and type 2 diabetes (T2D), well-controlled blood glucose (BG) is associated with lower mortality during hospitalization, according to a study published online May 1 in Cell Metabolism.

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High Clinical Burden Associated With Nonalcoholic Fatty Liver Disease

WEDNESDAY, May 6, 2020 (HealthDay News) -- The clinical burden associated with nonalcoholic fatty liver disease (NAFLD) is high, according to a study published online May 5 in Alimentary Pharmacology and Therapeutics.

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USPSTF Recommends Hep B Screening for Those at Increased Risk

TUESDAY, May 5, 2020 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends screening adolescents and adults at increased risk for hepatitis B virus (HBV) infection. These findings form the basis of a draft recommendation statement published online May 5 by the USPSTF.

Draft Evidence Review
Draft Recommendation Statement
Comment on Recommendation Statement

L-Thyroxine Does Not Improve Subclinical Hypothyroidism in ≥65s

TUESDAY, May 5, 2020 (HealthDay News) -- L-thyroxine does not improve hypothyroid symptoms or tiredness among older adults with subclinical hypothyroidism (SCH) and high symptom burden, according to a study published online May 5 in the Annals of Internal Medicine.

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Average of 11 Work Days Lost Due to Injury Per Person in U.S.

TUESDAY, May 5, 2020 (HealthDay News) -- Nonfatal injuries are costly, with a per-person average of approximately 11 lost work days and a value of $1,560 per year in the United States, according to a study published online May 4 in Injury Prevention.

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Race and Income Influence Risk for Severe COVID-19

TUESDAY, May 5, 2020 (HealthDay News) -- Race and income influence the risk for severe illness from COVID-19, according to a study published online April 28 in the American Journal of Preventive Medicine.

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Variation Seen in COVID-19 Tests, Hospitalization, Deaths Across NYC

TUESDAY, May 5, 2020 (HealthDay News) -- There is considerable variation in the rates of COVID-19 testing, hospitalization, and deaths across New York City boroughs, according to a research letter published online April 29 in the Journal of the American Medical Association.

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High Alcohol Consumption May Be Causally Tied to Stroke, PAD

TUESDAY, May 5, 2020 (HealthDay News) -- Higher alcohol consumption may be causally associated with an increased risk for stroke and peripheral artery disease, according to a study published online May 5 in Circulation: Genomic and Precision Medicine.

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ACE Inhibitors, ARBs Not Linked to Risk for COVID-19

TUESDAY, May 5, 2020 (HealthDay News) -- Use of angiotensin-converting enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs) and other classes of antihypertensive medications seem not to be associated with COVID-19, according to two studies published online May 1 in the New England Journal of Medicine.

Abstract/Full Text - Mancia
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Editorial

FDA Goes After Unproven COVID-19 Antibody Tests

MONDAY, May 4, 2020 (HealthDay News) -- The U.S. Food and Drug Administration said Monday it will crack down on the fraudulent COVID-19 antibody tests that have flooded the market.

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Johns Hopkins University

Evolocumab Does Not Impact Cognition in Atherosclerotic CVD

MONDAY, May 4, 2020 (HealthDay News) -- For patients with atherosclerotic cardiovascular disease and low-density lipoprotein cholesterol (LDL-C) ≥70 mg/dL or non-high-density cholesterol ≥100 mg/dL despite statin therapy, evolocumab has no impact on patient-reported cognitive function, according to a study published in the May 12 issue of the Journal of the American College of Cardiology.

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Editorial (subscription or payment may be required)

One-Third of U.S. Families Struggling to Meet Basic Needs

MONDAY, May 4, 2020 (HealthDay News) -- The COVID-19 pandemic is straining many families' abilities to meet basic needs, according to a study published April 28 by the Urban Institute.

Survey Findings

Sleep Apnea Tied to High Blood Glucose Levels Among Blacks

MONDAY, May 4, 2020 (HealthDay News) -- Black Americans with severe sleep apnea are more likely to have high blood glucose levels, according to a study published online April 28 in the Journal of the American Heart Association.

Abstract/Full Text

Guidelines Issued for Managing Eosinophilic Esophagitis

MONDAY, May 4, 2020 (HealthDay News) -- Recommendations are presented for the management of eosinophilic esophagitis (EoE) in clinical practice guidelines published in the May issue of Gastroenterology.

Guidelines (subscription or payment may be required)
Technical Review (subscription or payment may be required)

Posttraumatic Stress Symptoms Seen in China After COVID-19

MONDAY, May 4, 2020 (HealthDay News) -- Nearly one in 10 people in parts of China hit hardest by COVID-19 report posttraumatic stress symptoms (PTSS), according to a study published in the May issue of Psychiatry Research.

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Recommendations Made for PPE Use by HCPs in COVID-19 Care

MONDAY, May 4, 2020 (HealthDay News) -- In guidelines from the Infectious Diseases Society of America, recommendations are presented for personal protective equipment (PPE) use by health care providers (HCP) in caring for suspected or known COVID-19 patients.

Abstract/Full Text

Patients With Cancer Seem More Vulnerable to COVID-19

MONDAY, May 4, 2020 (HealthDay News) -- Patients with cancer seem to be more vulnerable to COVID-19 and have higher risks for severe outcomes, according to a study published online April 28 in Cancer Discovery.

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Hydroxychloroquine in COVID-19 Ups Risk for QTc Prolongation

MONDAY, May 4, 2020 (HealthDay News) -- Patients with COVID-19 who receive hydroxychloroquine have a high risk for corrected QT (QTc) prolongation, according to a study published online May 1 in JAMA Cardiology.

Abstract/Full Text
Editorial

ATS Issues Guideline on the Diagnosis of Sarcoidosis

MONDAY, May 4, 2020 (HealthDay News) -- In an official American Thoracic Society clinical practice guideline, published online April 15 in the American Journal of Respiratory and Critical Care Medicine, recommendations are presented for the detection and diagnosis of sarcoidosis.

Abstract/Full Text

Testing, Prescribing Increase After Change to TSH Reference Range

MONDAY, May 4, 2020 (HealthDay News) -- A minor planned decrease in the upper limit of the reference range for thyroid-stimulating hormone (TSH) resulted in an increase in levothyroxine prescriptions and more TSH measurements, according to a study published in the May 4 issue of CMAJ, the journal of the Canadian Medical Association.

Abstract/Full Text
Editorial

With Many States Reopening, COVID-19 Testing Levels Still Too Low

MONDAY, May 4, 2020 (HealthDay News) -- A new analysis shows inadequate levels of testing for COVID-19 in 60 percent of states, many of which are actively reopening after weeks of lockdown.

AP News Article

CV Outcomes Improved in Those With, Without Type 2 Diabetes

FRIDAY, May 1, 2020 (HealthDay News) -- Cardiovascular outcomes have improved since the 1990s, especially for individuals with type 2 diabetes, according to a study published online April 30 in the Journal of Clinical Endocrinology & Metabolism.

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Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 27 to May 1, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Black Patients Overrepresented in Hospitalized COVID-19 Cohort

FRIDAY, May 1, 2020 (HealthDay News) -- In a cohort of hospitalized adults with COVID-19, black patients have a similar probability of receiving invasive mechanical ventilation or dying compared with nonblack patients, but they are disproportionately represented among hospitalized patients, according to a study published online April 29 in the U.S. Centers for Disease Control and Prevention (CDC) Morbidity and Mortality Weekly Report.

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Incidence of Enteric Infections Due to Pathogens Up or Stable

FRIDAY, May 1, 2020 (HealthDay News) -- In 2019, the incidence of enteric infections caused by eight pathogens increased or remained stable, according to a study published May 1 in the U.S. Centers for Disease Control and Prevention (CDC) Morbidity and Mortality Weekly Report.

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Anosmia in COVID-19 Linked to Lower Risk for Admission

FRIDAY, May 1, 2020 (HealthDay News) -- For patients with COVID-19, anosmia is strongly associated with a reduced likelihood of being admitted to the hospital, according to a study published online April 24 in the International Forum of Allergy & Rhinology.

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Contact Tracing Can Cut Time to Case Isolation in SARS-CoV-2

FRIDAY, May 1, 2020 (HealthDay News) -- Contact tracing can reduce the time to case isolation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a study published online April 27 in The Lancet Infectious Diseases.

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Fear of COVID-19 Keeping Adults From Emergency Care

FRIDAY, May 1, 2020 (HealthDay News) -- Adults are avoiding emergency medical care for fear of catching COVID-19, according to a poll released April 28 by the American College of Emergency Physicians (ACEP).

ACEP Report

Lower Lean Body Mass With Aging May Up Diabetes Incidence in Men

FRIDAY, May 1, 2020 (HealthDay News) -- Changes in total lean body mass with aging are associated with the development of diabetes among men and women, according to a study published online April 30 in the Journal of the Endocrine Society.

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SGLT2 Inhibitors Linked to Reduced Risk for Serious Renal Events

FRIDAY, May 1, 2020 (HealthDay News) -- Use of sodium-glucose cotransporter 2 (SGLT2) inhibitors is associated with a reduced risk for serious renal events compared with dipeptidyl peptidase-4 inhibitors, according to a study published online April 29 in The BMJ.

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Impact of COVID-19 on Oncology Clinical Trials Discussed

FRIDAY, May 1, 2020 (HealthDay News) -- The impact of COVID-19 on oncology clinical trials and long-term implications are discussed in a study and recommendations published in JCO Oncology Practice.

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ASCO Recommendations

Vascular Stiffness Similar in E-, Combustible Cigarette Users

FRIDAY, May 1, 2020 (HealthDay News) -- Electronic cigarette (e-cigarette) use with or without combustible cigarette use is associated with a similar elevation in the augmentation index compared with combustible cigarette use alone, according to a study published online April 29 in the Journal of the American Heart Association.

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RV Strain on Echocardiogram May ID High-Risk COVID-19 Patients

FRIDAY, May 1, 2020 (HealthDay News) -- Right ventricular longitudinal strain (RVLS) is a predictor of mortality in patients with COVID-19, according to a study published online April 28 in JACC: Cardiovascular Imaging.

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