October 2018 Briefing - Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for October 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Greater Weight Loss With Gastric Bypass Than Other Bariatric Sx

WEDNESDAY, Oct. 31, 2018 (HealthDay News) -- Roux-en-Y gastric bypass (RYGB) is associated with greater weight loss at one, three, and five years than sleeve gastrectomy (SG) or adjustable gastric banding (AGB), though it also has the highest rate of 30-day adverse events, according to a study published Oct. 29 in the Annals of Internal Medicine.

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Opioid Use Often Persists in Workers' Compensation Claimants

WEDNESDAY, Oct. 31, 2018 (HealthDay News) -- Many patients in a workers' compensation cohort have persistent opioid use, according to a study published online Oct. 26 in JAMA Network Open.

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Link Between Statins, Non-CVD Outcomes Lacks Evidence

WEDNESDAY, Oct. 31, 2018 (HealthDay News) -- There is a lack of convincing evidence for an association between statin use and non-cardiovascular disease (CVD) outcomes, according to a review published in the Oct. 16 issue of the Annals of Internal Medicine.

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Black, Low-Income Women May Not Report Barriers to Care

WEDNESDAY, Oct. 31, 2018 (HealthDay News) -- Black women, women living in poverty, and those with higher levels of distrust are less likely to report barriers to timely screening mammography, according to a study published online Sept. 24 in Cancer.

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Erectile Dysfunction Common in Childhood Cancer Survivors

TUESDAY, Oct. 30, 2018 (HealthDay News) -- The prevalence of erectile dysfunction (ED) is 29 percent among male childhood cancer survivors (CCS), according to a research letter published online Oct. 4 in JAMA Oncology.

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AMA Announces Initiative to Reinvent Physician Training

TUESDAY, Oct. 30, 2018 (HealthDay News) -- The American Medical Association (AMA) today announced a new $15 million competitive grant initiative, the "Reimagining Residency" initiative, aimed at improving residency training.

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Psoriasis Linked to Increased Risk for Inflammatory Bowel Disease

TUESDAY, Oct. 30, 2018 (HealthDay News) -- Psoriasis appears to be significantly associated with inflammatory bowel disease (IBD), according to a review published online Oct. 24 in JAMA Dermatology.

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Angiotensin-Converting Enzyme Inhibitors May Up Lung CA Risk

TUESDAY, Oct. 30, 2018 (HealthDay News) -- The use of angiotensin-converting enzyme inhibitors (ACEIs) is associated with an increased risk for lung cancer compared with angiotensin receptor blockers, according to a study published online Oct. 24 in the BMJ.

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Mortality Among Young People Declined From 1999 to 2015

TUESDAY, Oct. 30, 2018 (HealthDay News) -- Mortality rates for infants and youths generally declined in the United States from 1999 to 2015, though they remain higher than rates in Canada and England/Wales, with especially high rates among black and American Indian/Alaskan Native youth, according to a study published online Oct. 1 in JAMA Pediatrics.

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Community Health Worker Intervention Beneficial

TUESDAY, Oct. 30, 2018 (HealthDay News) -- A standardized community health worker (CHW)-delivered intervention, Individual Management for Patient-Centered Targets, improves patient-perceived quality of care and reduces hospitalizations for low-income patients with chronic diseases, according to a study published online Oct. 22 in JAMA Internal Medicine.

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Therapeutic Lifestyle Intervention in Church Helpful for BP Control

TUESDAY, Oct. 30, 2018 (HealthDay News) -- A therapeutic lifestyle change (TLC) intervention plus motivational interviewing (MINT) sessions delivered in churches can reduce systolic blood pressure (BP) among blacks compared with health education (HE) alone, according to a study published online Oct. 9 in Circulation: Cardiovascular Quality and Outcomes.

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Low Levels of Flu Reported in U.S. From May to October

MONDAY, Oct. 29, 2018 (HealthDay News) -- From May 20 to Oct. 13, 2018, low levels of influenza activity were reported in the United States, according to a study published online Oct. 25 in Morbidity and Mortality Weekly Report.

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Many Hospitals Noncompliant With Record Request Regulations

MONDAY, Oct. 29, 2018 (HealthDay News) -- Among top-ranked U.S. hospitals, data reveal discrepancies in information provided to patients regarding medical records release processes as well as noncompliance with state and federal regulations, according to a study published online Oct. 5 in JAMA Network Open.

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Nurse-Led Care Efficacious, Cost-Effective for Gout

MONDAY, Oct. 29, 2018 (HealthDay News) -- For patients with gout, nurse-led care is efficacious and cost-effective compared with usual care led by general practitioners (GPs), according to a study published Oct. 20 in The Lancet.

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Healthier Diet Tied to Lower Mortality Risk in CRC Patients

MONDAY, Oct. 29, 2018 (HealthDay News) -- Colorectal cancer (CRC) patients who follow healthy diets before or after diagnosis have a decreased risk for mortality, according to a study published online Oct. 19 in the Journal of Clinical Oncology.

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ASN: Home Dialysis Associated With Improved Survival

MONDAY, Oct. 29, 2018 (HealthDay News) -- Home hemodialysis (HHD) is associated with better survival than in-center hemodialysis (IHD) among incident dialysis patients, according to a study presented at the American Society of Nephrology's Kidney Week, held Oct. 23 to 28 in San Diego.

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In Complicated UTI, Cefiderocol Noninferior to Imipenem-Cilastin

MONDAY, Oct. 29, 2018 (HealthDay News) -- For complicated urinary tract infections caused by multidrug-resistant Gram-negative uropathogens, the siderophore cephalosporin cefiderocol is non-inferior to imipenem-cilastatin, according to a study published online Oct. 25 in The Lancet Infectious Diseases.

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Trump Administration Announces Plan to Cut Drug Prices

FRIDAY, Oct. 26, 2018 (HealthDay News) -- In an effort to cut high drug costs, the prices paid by Medicare for certain prescription drugs would be based on those in other advanced industrial nations, according to a proposal announced Oct. 25 by the Trump administration.

HHS Study
New York Times Article

Alcohol Disorder Screening in Women Post-RYGB Inadequate

FRIDAY, Oct. 26, 2018 (HealthDay News) -- Assessing the frequency and quantity of alcohol consumption may be inadequate for identifying alcohol-related problems in women who have undergone Roux-en-Y gastric bypass (RYGB) surgery, according to a study published online Oct. 11 in the Annals of Surgery.

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Pneumococcal Vaccine Recs Cause Confusion Among Docs

THURSDAY, Oct. 25, 2018 (HealthDay News) -- While primary care physicians overwhelmingly recommend pneumococcal vaccines, there is a gap in their knowledge of how to implement related vaccine recommendations, according to a study published in the Journal of the American Board of Family Medicine.

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Oxygen Saturation Should Not Top 96 Percent in Acutely Ill

THURSDAY, Oct. 25, 2018 (HealthDay News) -- For acutely ill patients, an oxygen saturation of no more than 96 percent should be maintained, according to a clinical practice guideline published online Oct. 24 in the BMJ.

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Independent Links for Genetics, Lifestyle With Incident Stroke

THURSDAY, Oct. 25, 2018 (HealthDay News) -- Genetic and lifestyle factors are independently associated with incident stroke among men and women aged 40 to 73 years, according to a study published online Oct. 24 in the BMJ.

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Pace of Change Has Accelerated in Alternative Payment Models

THURSDAY, Oct. 25, 2018 (HealthDay News) -- The impact of alternative payment models (APMs) on physician practices has been described in a study published by the RAND Corp. and the American Medical Association.

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Allopurinol Linked to Reduced Risk for CKD Stage ≥3 in Gout

THURSDAY, Oct. 25, 2018 (HealthDay News) -- For patients with gout, allopurinol is associated with a reduced risk for developing chronic kidney disease stage ≥3, according to a study published online Oct. 8 in JAMA Internal Medicine.

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Half of Women to Develop Stroke, Dementia, or Parkinsonism

THURSDAY, Oct. 25, 2018 (HealthDay News) -- One in two women and one in three men will develop dementia, stroke, or parkinsonism during their lifetime, according to a study published online Oct. 1 in the Journal of Neurology, Neurosurgery & Psychiatry.

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Algorithm-Defined Tx Duration Non-Inferior in Staph Bacteremia

WEDNESDAY, Oct. 24, 2018 (HealthDay News) -- For patients with staphylococcal bacteremia, an algorithm that defines treatment duration results in a non-inferior rate of clinical success compared with usual care, according to a study published in the Sept. 25 issue of the Journal of the American Medical Association.

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Almost One in 10 Treated in Hospital for Non-Fatal Injury

WEDNESDAY, Oct. 24, 2018 (HealthDay News) -- In 2013, 9.8 per 100 people were treated in the hospital for a non-fatal injury, with costs estimated at $1.853 trillion, according to a study published online Oct. 8 in Injury Epidemiology.

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Tibia Lead Levels Linked to Risk of Resistant-Hypertension

WEDNESDAY, Oct. 24, 2018 (HealthDay News) -- Tibia lead levels are associated with resistant-hypertension (HTN), according to a study published online Oct. 24 in the Journal of the American Heart Association.

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7 Children Dead From Adenovirus Outbreak in New Jersey

WEDNESDAY, Oct. 24, 2018 (HealthDay News) -- New Jersey health officials on Wednesday confirmed the deaths of seven children after infection with an adenovirus.

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Article from The Record (Bergen County)

AGA Issues Guidelines for Opioid-Induced Constipation

WEDNESDAY, Oct. 24, 2018 (HealthDay News) -- Recommendations for medical management of opioid-induced constipation include laxatives as first-line agents, according to a guideline from the American Gastroenterological Association (AGA) published online Oct. 17 in Gastroenterology.

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Most Supplements Contain Prohibited Stimulants

WEDNESDAY, Oct. 24, 2018 (HealthDay News) -- Many supplements contain one or more stimulants that have been the subject of U.S. Food and Drug Administration-issued public notices, according to a research letter published online Oct. 22 in JAMA Internal Medicine.

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High-Dose Flu Vaccine May Cut Hospitalization in Dialysis Patients

WEDNESDAY, Oct. 23, 2018 (HealthDay News) -- Receipt of the high-dose influenza vaccine in 2016 to 2017 was associated with lower rates of hospitalization among dialysis patients, according to a study published online Oct. 23 in the Clinical Journal of the American Society of Nephrology.

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Health Enterprise Zone Initiative Cut Hospitalizations, Costs

WEDNESDAY, Oct. 24, 2018 (HealthDay News) -- Maryland's Health Enterprise Zone Initiative reduced hospitalizations and led to net cost savings, according to a study published in the October issue of Health Affairs.

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USPSTF Recommends Screening Women for Partner Violence

TUESDAY, Oct. 23, 2018 (HealthDay News) -- Clinicians should screen women of reproductive age for intimate partner violence (IPV) and refer women to ongoing support services if necessary, according to a U.S. Preventive Services Task Force (USPSTF) final recommendation statement published in the Oct. 23/30 issue of the Journal of the American Medical Association.

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Preeclampsia Tied to Increased Risk for Vascular Dementia

TUESDAY, Oct. 23, 2018 (HealthDay News) -- Preeclampsia seems to be associated with an increased risk for dementia, especially vascular dementia, with a stronger correlation for late-onset disease, according to a study published online Oct. 17 in The BMJ.

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White House Unveils New Insurance Option for Small Firms

TUESDAY, Oct. 23, 2018 (HealthDay News) -- A plan to allow small businesses to use tax-free accounts to provide health coverage for employees was announced today by the Trump administration.

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Periodontitis Linked to Higher BP in Adults With Treated HTN

TUESDAY, Oct. 23, 2018 (HealthDay News) -- For adults with treated hypertension, periodontitis is associated with higher mean systolic blood pressure (BP) and with increased odds of unsuccessful hypertensive treatment, according to a study published online Oct. 22 in Hypertension.

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Inadequate Reimbursement May Mar Diabetes Prevention Program

TUESDAY, Oct. 23, 2018 (HealthDay News) -- The costs of delivering a new Medicare Diabetes Prevention Program (MDPP) may be higher than the expected reimbursement, according to a study published in the November issue of Medical Care.

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Neglect Higher in For-Profit Nursing Homes

TUESDAY, Oct. 23, 2018 (HealthDay News) -- Residents of for-profit nursing homes are more likely to suffer neglect compared with elderly residents living in the community or in not-for-profit facilities, according to a study published online Oct. 9 in Gerontology.

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Intensive SBP Tx Cuts Kidney Damage Biomarkers in Incident CKD

TUESDAY, Oct. 23, 2018 (HealthDay News) -- Patients with incident chronic kidney disease (CKD) in the setting of intensive systolic blood pressure (SBP) treatment have decreases rather than increases in kidney damage biomarkers, according to a study published online Oct. 23 in the Annals of Internal Medicine.

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Diagnostic Strategy Can Rule Out PE in Pregnant Women

MONDAY, Oct. 22, 2018 (HealthDay News) -- A diagnostic strategy based on pretest clinical probability assessment, high-sensitivity D-dimer testing, bilateral lower-limb compression ultrasonography (CUS), and computed tomography pulmonary angiography (CTPA) can safely rule out pulmonary embolism (PE) in pregnant women, according to a study published online Oct. 23 in the Annals of Internal Medicine.

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Guidelines Outlined to Ease Peds Transition to Adult Health Care

MONDAY, Oct. 22, 2018 (HealthDay News) -- Guidelines have been updated to support the health care transition from adolescence to adulthood, according to a clinical report published online Oct. 22 in Pediatrics.

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Percent Weight Regain Predicts Health Risks Post-Bariatric Surgery

MONDAY, Oct. 22, 2018 (HealthDay News) -- Measuring the percentage of weight regained following the maximum amount of weight lost after Roux-en-Y gastric bypass (RYGB) surgery best predicts a patient's risk for several serious health problems, according to a study published in the Oct. 16 issue of the Journal of the American Medical Association.

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Glucose Dysregulation Seen Years Before Diabetes Diagnosis

MONDAY, Oct. 22, 2018 (HealthDay News) -- Individuals who develop diabetes or prediabetes have elevated fasting plasma glucose (FPG) at least 10 years before diagnosis, according to an observational study recently published in the Journal of the Endocrine Society.

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CDC: First U.S. Case of Rat-Borne Andes Virus Diagnosed

FRIDAY, Oct. 19, 2018 (HealthDay News) -- The first confirmed U.S. case of a virus carried by South American rodents occurred earlier this year, the U.S. Centers for Disease Control and Prevention says.

CNN Article
CDC Case Report

Variability in Geographic Availability of New Antibiotics

FRIDAY, Oct. 19, 2018 (HealthDay News) -- There is considerable variability in the geographic availability of antibiotics, according to a study published online Oct. 16 in PLOS ONE.

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Limited Success for Changing Diet and Exercise Among Nurses

FRIDAY, Oct. 19, 2018 (HealthDay News) -- Implementation of a workplace intervention to change diet and physical activity (PA) behavior was partially successful among nurses, with the ability to change both diet and PA at the same time described as challenging, according to a study recently published in the Journal of Nutrition Education and Behavior.

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Transcatheter Mitral Valve Repair Benefits Some With Heart Failure

FRIDAY, Oct. 19, 2018 (HealthDay News) -- Transcatheter mitral-valve repair results in a lower rate of hospitalization and lower all-cause mortality than medical therapy alone among patients with heart failure and moderate-to-severe secondary mitral regurgitation who remain symptomatic despite the use of guideline-directed medical therapy, according to a study published online Sept. 23 in the New England Journal of Medicine.

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Poor Experience With PCP Linked to Hospitalization in CKD

FRIDAY, Oct. 19, 2018 (HealthDay News) -- For Hispanic patients with chronic kidney disease (CKD), lower perceived quality of the patient experience with their primary care physician is associated with increased risk of hospitalization, according to a study published online Oct. 18 in the Clinical Journal of the American Society of Nephrology.

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2014 to 2016 Saw 470 Percent Increase in HIV PrEP Use in U.S.

FRIDAY, Oct. 19, 2018 (HealthDay News) -- From 2014 to 2016 there was an increase in the annual number of HIV preexposure prophylaxis (PrEP) users in the United States, although only about 7 percent of those with indications for PrEP were prescribed PrEP in 2016, according to research published in the Oct. 18 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Triple Combo Regimens May Address Cause of Cystic Fibrosis

FRIDAY, Oct. 19, 2018 (HealthDay News) -- Triple therapy with VX-659 or VX-445 combined with tezacaftor-ivacaftor shows promise for the treatment of adult patients with cystic fibrosis who have mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), according to two studies published online Oct. 18 in the New England Journal of Medicine. The studies were published to coincide with a presentation at the annual North American Cystic Fibrosis Conference, held from Oct. 18 to 20 in Denver.

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Bioinformatics Tool Can ID Source of Bloodstream Pathogens

FRIDAY, Oct. 19, 2018 (HealthDay News) -- A streamlined bioinformatics tool can match bloodstream pathogens to a candidate source, according to a study published online Oct. 15 in Nature Medicine.

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Mortality Due to Suicide, Alcohol, Accidents Up in Diabetes

THURSDAY, Oct. 18, 2018 (HealthDay News) -- Patients with diabetes have increased mortality due to suicide, alcohol-related causes, and accidents than those without diabetes, according to a study published in the November issue of the European Journal of Endocrinology.

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Sharp Drop in U.S. Life Expectancy Rankings by 2040

THURSDAY, Oct. 18, 2018 (HealthDay News) -- The United States will have the largest drop in life expectancy rankings of all high-income countries by 2040, a new study says.

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WHO: Congo Ebola Outbreak Not a Global Emergency

THURSDAY, Oct. 18, 2018 (HealthDay News) -- The latest Ebola outbreak in Congo is not yet severe enough to be declared a global emergency, the World Health Organization decided after a meeting of experts yesterday.

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Clostridium difficile Spores Survive Laundering of Sheets

WEDNESDAY, Oct. 17, 2018 (HealthDay News) -- Clostridium difficile spores are able to survive laundering through a commercial washer extractor, according to a study published online Oct. 16 in Infection Control & Hospital Epidemiology.

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Procurement Requirements Drive Interoperability in Health Care IT

THURSDAY, Oct. 18, 2018 (HealthDay News) -- Interoperability of health care information technology (IT) must be improved to facilitate creation of a fully integrated health care system that can improve health and health care at lower cost, according to a report published by the National Academy of Medicine.

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Consuming Caffeine From Coffee Reduces Incident Rosacea

THURSDAY, Oct. 18, 2018 (HealthDay News) -- Caffeine intake from coffee is inversely associated with the risk for incident rosacea, according to a study published online Oct. 17 in JAMA Dermatology.

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Limited Evidence for OTC Preps to Treat Nasal Symptoms of Colds

THURSDAY, Oct. 18, 2018 (HealthDay News) -- Limited evidence is available for over-the-counter (OTC) treatments for nasal symptoms of the common cold, according to a report published online Oct. 10 in The BMJ.

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CDC Warns of Salmonella Illnesses Linked to Raw Chicken

WEDNESDAY, Oct. 17, 2018 (HealthDay News) -- The number of people sickened in a Salmonella outbreak linked to raw chicken products now stands at 92 people in 29 states, U.S. health officials said today.

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Recreational Marijuana Now Legal in Canada

WEDNESDAY, Oct. 17, 2018 (HealthDay News) -- Recreational marijuana became legal in Canada today, and while many welcome the move, others have serious concerns.

The New York Times Article
CMAJ Editorial

Giving Flu Shots in Pharmacies Could Up Vaccination Coverage

WEDNESDAY, Oct. 16, 2018 (HealthDay News) -- Administering influenza vaccines through pharmacies in addition to traditional locations can increase vaccination coverage in the event of an epidemic, according to a study published online Oct. 16 in Vaccine.

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Lung Cancer Deaths 28% Lower in California Than Rest of U.S.

WEDNESDAY, Oct. 17, 2018 (HealthDay News) -- Annual lung cancer mortality was 28 percent lower in California than in the rest of the United States in 2013, according to a study published online Oct. 10 in Cancer Prevention Research.

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Seven-Day Metronidazole Better for Trichomoniasis Tx in Women

WEDNESDAY, Oct. 17, 2018 (HealthDay News) -- A seven-day dose of metronidazole is associated with a reduced likelihood of being Trichomonas vaginalis-positive at test-of-cure compared with single-dose treatment, according to a study published online Oct. 5 in The Lancet Infectious Diseases.

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Bariatric Sx Cuts Macrovascular Complications in Obesity, T2DM

TUESDAY, Oct. 15, 2018 (HealthDay News) -- For patients with severe obesity and type 2 diabetes, bariatric surgery is associated with a lower risk for macrovascular outcomes compared with not undergoing surgery, according to a study published in the Oct. 16 issue of the Journal of the American Medical Association.

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Gastric Banding, Metformin Similar for Improving Glycemia

TUESDAY, Oct. 16, 2018 (HealthDay News) -- In adults with moderate obesity and either impaired glucose tolerance (IGT) or recently diagnosed mild type 2 diabetes (T2D), gastric banding and metformin are similarly effective for slowing disease progression over a two-year period, according to a study published online Oct. 3 in Diabetes Care.

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High Risk for Readmission for Takotsubo Syndrome

TUESDAY, Oct. 16, 2018 (HealthDay News) -- Patients with Takotsubo syndrome (TTS), which is characterized by transient left ventricular dysfunction with symptoms and electrocardiogram changes mimicking acute myocardial infarction (AMI), have lower mortality during the index admission than AMI patients but are frequently readmitted within 30 days, according to a study published online Sept. 28 in the European Heart Journal - Quality of Care & Clinical Outcomes.

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Web-Based Lifestyle Program Works for Liver Disease Patients

TUESDAY, Oct. 16, 2018 (HealthDay News) -- Web-based programs may be effective in helping patients make lifestyle changes to control non-alcoholic fatty liver disease (NAFLD), according to a study published in the November issue of the Journal of Hepatology.

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2006 to 2015 Saw Decrease in Medicare Beneficiary ICU Use

TUESDAY, Oct. 16, 2018 (HealthDay News) -- From 2006 to 2015, there was a significant decrease in intensive care unit (ICU) admissions among Medicare fee-for-service beneficiaries, according to a research letter published online Oct. 15 in the Annals of Internal Medicine.

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β-Blockers in 1st Trimester Do Not Up Congenital Malformations

MONDAY, Oct. 15, 2018 (HealthDay News) -- Maternal use of β-blockers in the first trimester of pregnancy is not associated with a large increase in the risk for overall or cardiac congenital malformations, according to a study published online Oct. 16 in the Annals of Internal Medicine.

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Without Medicaid Expansion, Poor Patients Forgo Medical Care

MONDAY, Oct. 15, 2018 (HealthDay News) -- Doing without medical care is much more common among low-income residents of states that have not expanded Medicaid than among low-income people in other states, according to a Government Accountability Office report.

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Cataract Surgery Tied to Drop in Cognitive Decline in Seniors

MONDAY, Oct. 15, 2018 (HealthDay News) -- Cataract surgery is associated with a reduction in the rate of cognitive decline among older adults, according to a study published online Oct. 11 in PLOS ONE.

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Cases Show Periodic Fasting May Cut Medication Use in T2DM

MONDAY, Oct. 15, 2018 (HealthDay News) -- Medically supervised, therapeutic fasting regimens can help reverse type 2 diabetes (T2D) and minimize the need for pharmacological interventions, according to a case series published online Oct. 9 in BMJ Case Reports.

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More Socioeconomic Challenges for Hispanic Women With HIV

MONDAY, Oct. 15, 2018 (HealthDay News) -- Hispanic/Latino women with HIV infection face more socioeconomic and language challenges than men, but the clinical outcomes are similar, according to research published in the Oct. 12 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Active Pharmaceuticals ID'd in >700 Dietary Supplements

MONDAY, Oct. 15, 2018 (HealthDay News) -- Dietary supplements often include active pharmaceuticals, even after warnings from the U.S. Food and Drug Administration, according to a study published online Oct. 12 in JAMA Network Open.

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High Variability in Metabolic Measures May Up Mortality

MONDAY, Oct. 15, 2018 (HealthDay News) -- High variability in metabolic parameters is associated with increased risk for mortality and cardiovascular events, according to a study published online Oct. 1 in Circulation.

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Multicomponent Intervention Can Reduce Sitting Time at Work

FRIDAY, Oct. 12, 2018 (HealthDay News) -- A multicomponent intervention (Stand More At [SMArT] Work) can reduce sitting time over the short, medium, and long terms, according to a study published online Oct. 10 in The BMJ.

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Zoledronate Lowers Fracture Risk in Women With Osteopenia

FRIDAY, Oct. 12, 2018 (HealthDay News) -- The risk for fragility fractures is significantly lower in women with osteopenia who receive zoledronate than in those who receive placebo, according to a study published online Oct. 1 in the New England Journal of Medicine.

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Modest Alcohol Consumption May Reduce Mortality in NAFLD

FRIDAY, Oct. 12, 2018 (HealthDay News) -- For patients with nonalcoholic fatty liver disease (NAFLD), modest alcohol consumption is associated with a reduction in all-cause mortality, while drinking 1.5 or more drinks per day may increase mortality, according to a study recently published in Hepatology.

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High Circulating Prolactin Level Inversely Linked to T2DM Risk

FRIDAY, Oct. 12, 2018 (HealthDay News) -- Among U.S. women, a normally high circulating prolactin concentration is associated with a reduced risk for type 2 diabetes, according to a study published online Oct. 11 in Diabetologia.

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Hormone Therapy Not Beneficial in Subclinical Hypothyroidism

FRIDAY, Oct. 12, 2018 (HealthDay News) -- Thyroid hormone therapy is not associated with improvements in general quality of life or thyroid-related symptoms in non-pregnant adults with subclinical hypothyroidism, according to a review published in the Oct. 2 issue of the Journal of the American Medical Association.

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Skills-Based Intervention Did Not Cut Systolic BP After Stroke, TIA

FRIDAY, Oct. 12, 2018 (HealthDay News) -- A culturally tailored, skills-based educational intervention did not reduce systolic blood pressure at one year after stroke/transient ischemic attack, according to a study published online Oct. 8 in JAMA Neurology.

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Spending Often Persists in High-Cost Medicare-Medicaid Eligible

THURSDAY, Oct. 11, 2018 (HealthDay News) -- More than half of patients who are dually eligible for Medicare and Medicaid and are designated as high-cost in one year remain persistently high-cost over three years, according to a study published online Oct. 2 in the Annals of Internal Medicine.

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Low-Dose Aspirin May Reduce Ovarian Cancer Risk

THURSDAY, Oct. 11, 2018 (HealthDay News) -- Low-dose aspirin use is associated with a reduced risk for ovarian cancer, according to a study published online Oct. 4 in JAMA Oncology.

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Diet Less Important Than Genes for High Serum Urate Levels

THURSDAY, Oct. 11, 2018 (HealthDay News) -- Diet explains little of the variation in serum urate levels in the general population, while genetic factors make a greater contribution, according to a meta-analysis published online Oct. 10 in The BMJ.

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Midlife PSA Predicts Aggressive Prostate Cancer in Black Men

THURSDAY, Oct. 11, 2018 (HealthDay News) -- Midlife levels of prostate-specific antigen (PSA) strongly predict future development of aggressive prostate cancer among black men, according to a study published online Sept. 17 in European Urology.

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Payer Policies May Discourage Non-Pharma Tx for Low Back Pain

THURSDAY, Oct. 11, 2018 (HealthDay News) -- There is a need for public and private insurers to broaden their coverage policies for non-drug pain treatments for low back pain, according to a study published online Oct. 5 in JAMA Network Open.

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Review: Vitamin D Does Not Appear to Prevent Fractures, Falls

THURSDAY, Oct. 11, 2018 (HealthDay News) -- Vitamin D supplementation does not prevent fractures or falls or have a clinically meaningful impact on bone mineral density in pooled analyses, according to a review and meta-analysis published online Oct. 4 in The Lancet Diabetes & Endocrinology.

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On a Given Day, 36.6 Percent of U.S. Adults Eat Fast Food

THURSDAY, Oct. 11, 2018 (HealthDay News) -- Overall, 36.6 percent of U.S. adults consumed fast food on a given day during 2013 to 2016, according to an October data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Renal-Replacement Timing Has No Effect in Kidney Injury, Sepsis

WEDNESDAY, Oct. 10, 2018 (HealthDay News) -- For patients with early-stage septic shock and severe acute kidney injury, 90-day mortality does not differ for patients randomly assigned to an early strategy for initiation of renal-replacement therapy versus a delayed strategy, according to a study published in the Oct. 11 issue of the New England Journal of Medicine.

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Atrial Fibrillation Tied to Higher Dementia Risk in Older Adults

WEDNESDAY, Oct. 10, 2018 (HealthDay News) -- Atrial fibrillation (AF) is associated with a faster global cognitive decline and an increased risk for dementia in older people, though anticoagulants may reduce dementia risk in AF patients, according to a study published online Oct. 10 in Neurology.

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Aetna-CVS Merger Approved

WEDNESDAY, Oct. 10, 2018 (HealthDay News) -- A $69 billion merger between health insurer Aetna and pharmacy manager CVS Health has been approved, according to the U.S. Justice Department.

The New York Times Article

ADA, EASD Issue New Recommendations for T2DM

WEDNESDAY, Oct. 10, 2018 (HealthDay News) -- Recommendations for the management of type 2 diabetes have been updated, according to a consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) published online Oct. 5 in Diabetes Care.

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Prevalence of Anxiety, Depression Up for Adults With Arthritis

WEDNESDAY, Oct. 10, 2018 (HealthDay News) -- The age-standardized prevalences of symptoms of anxiety and depression among adults with arthritis are 22.5 and 12.1 percent, which are considerably higher than those among adults without arthritis, according to research published in the Oct. 5 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Long-Term Aspirin Use Linked to Reduction in Liver Cancer Risk

WEDNESDAY, Oct. 10, 2018 (HealthDay News) -- Regular long-term aspirin use is associated with a dose-dependent reduction in the risk for hepatocellular carcinoma (HCC), according to a study published online Oct. 4 in JAMA Oncology.

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Retention in HIV Care Drops Steadily After Prison Release

WEDNESDAY, Oct. 10, 2018 (HealthDay News) -- For criminal justice-involved persons living with HIV (PLWH), sustained retention in care decreases over time post-release, according to a study published online Oct. 9 in PLOS Medicine.

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Intensive BP Therapy in Diabetes May Lower Risk for CV Events

WEDNESDAY, Oct. 10, 2018 (HealthDay News) -- Intensive blood pressure (BP) therapy is associated with significantly lower risk for cardiovascular events based on data reweighted to better reflect the U.S. adult population with diabetes, according to a study published in the Sept. 11 issue of the Journal of the American College of Cardiology.

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Halobetasol Propionate Lotion Shows Efficacy for Tx of Psoriasis

WEDNESDAY, Oct. 10, 2018 (HealthDay News) -- Halobetasol propionate 0.01 percent lotion (BRYHALI Lotion) appears safe and effective for the treatment of moderate-to-severe plaque psoriasis, according to the results of two phase 3 trials published in the October issue of the Journal of Drugs in Dermatology.

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Flea-Borne Typhus Outbreak in Los Angeles County

TUESDAY, Oct. 9, 2018 (HealthDay News) -- An outbreak of flea-borne typhus in Los Angeles County has so far resulted in 57 cases, including 20 in Pasadena and nine in downtown Los Angeles, public health officials say.

CNN Article
More Information: CDC

FDA Approves HPV Vaccine for People Through Age 45

TUESDAY, Oct. 9, 2018 (HealthDay News) -- U.S. Food and Drug Administration approval of the Gardasil 9 human papillomavirus (HPV) vaccine has been expanded to include people ages 27 through 45, the agency said in a news release.

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FDA Approves Marketing of First User-Fitted Hearing Aid

TUESDAY, Oct. 9, 2018 (HealthDay News) -- The first hearing aid that does not require the assistance of an audiologist or other health care provider has been approved by the U.S. Food and Drug Administration.

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Weight Loss May Cut Breast CA Risk in Postmenopausal Women

TUESDAY, Oct. 9, 2018 (HealthDay News) -- Postmenopausal women with weight loss have a reduced risk for breast cancer, according to a study published online Oct. 8 in Cancer.

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Risk of Opioid-Benzodiazepine Overlap Up for Dual Prescribing

TUESDAY, Oct. 9, 2018 (HealthDay News) -- Receiving prescriptions from both the U.S. Department of Veterans Affairs (VA) and Medicare Part D is associated with increased risk for overlapping of opioid and benzodiazepine prescriptions, according to a study published online Oct. 9 in the Annals of Internal Medicine.

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Minority Residents Experience Burdens Linked to Race/Ethnicity

TUESDAY, Oct. 9 2018 (HealthDay News) -- Minority residents describe burdens associated with race/ethnicity, including microaggressions and bias on a daily basis, according to a study published online Sept. 28 in JAMA Network Open.

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Application of Blood Pressure Guidelines Ups Treatment

TUESDAY, Oct. 9, 2018 (HealthDay News) -- Implementation of the 2017 American College of Cardiology/American Heart Association (ACC/AHA) blood pressure guideline would direct initiation and intensification of antihypertensive medication treatment to adults at high risk for cardiovascular disease (CVD) events, according to a study published in the Sept. 11 issue of the Journal of the American College of Cardiology.

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Congress Passes Bill to Fight Opioid Crisis

FRIDAY, Oct. 5, 2018 (HealthDay News) -- A bipartisan bill to fight the opioid addiction crisis in the United States has been passed by Congress. President Donald Trump said he would sign the bill into law.

AP News Article

AZ Company Recalls Raw Beef Products Linked to Salmonella

FRIDAY, Oct. 5, 2018 (HealthDay News) -- An Arizona company has recalled more than 6.5 million pounds (2.9 million kilograms) of beef linked to a Salmonella outbreak that has sickened 57 people in 16 states. Fourteen people have been hospitalized. No deaths have been reported, according to the U.S. Centers for Disease Control and Prevention.

AP News Article
CDC Food Safety Alert

Industry-Funded Trials Often Involve Employees in Studies

FRIDAY, Oct. 5, 2018 (HealthDay News) -- Industry employees are often involved in the design, conduct, and reporting of industry-funded trials in high-impact journals, according to a study published online Oct. 3 in The BMJ.

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No Increase in In-Hospital, Post-Discharge Death With HRRP

FRIDAY, Oct. 5, 2018 (HealthDay News) -- Announcement and implementation of the Hospital Readmissions Reduction Program (HRRP) was not associated with increases in in-hospital or post-discharge mortality after acute myocardial infarction (AMI), heart failure, or pneumonia, according to a study published online Sept. 28 in JAMA Network Open.

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Digital Cognitive Therapy Eases Daytime Effects of Insomnia

FRIDAY, Oct. 5, 2018 (HealthDay News) -- Digital cognitive behavioral therapy (dCBT) is effective in improving functional health, psychological well-being, and sleep-related quality of life in people reporting insomnia, according to a study published online Sept. 25 in JAMA Psychiatry.

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Sexual Harassment, Assault Tied to Women's Health Issues

FRIDAY, Oct. 5, 2018 (HealthDay News) -- Sexual harassment and sexual assault among midlife women are associated with poorer physical and mental health, according to a study published online Oct. 3 in JAMA Internal Medicine.

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Daily Drinking Associated With Increased Mortality Risk

FRIDAY, Oct. 5, 2018 (HealthDay News) -- Daily drinking, even at low levels, may be detrimental to one's health, according to a study published online Oct. 3 in Alcoholism: Clinical & Experimental Research.

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Three-Quarters of Health Care Workers Got Flu Shot Last Year

THURSDAY, Oct. 4, 2018 (HealthDay News) -- Just over three-quarters of health care personnel received a flu vaccine last season, according to research published in the Sept. 28 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Price Hikes Noted in Small Subset of Generic Drugs

THURSDAY, Oct. 4, 2018 (HealthDay News) -- A small but growing subset of generic drugs experienced sudden large price increases from 2007 to 2013, according to a study published in the October issue of Health Affairs.

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Tips Provided for Budgeting in Medical Residency

THURSDAY, Oct. 4, 2018 (HealthDay News) -- Medical residents should start budgeting and save for the future, according to an article published in the American Medical Association AMA Wire.

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Cancer Risk Varies for Hispanics, Including in Puerto Rico

THURSDAY, Oct. 4, 2018 (HealthDay News) -- Hispanics have lower incidence and mortality than non-Hispanic whites for all cancers combined, although there is considerable variability in cancer risk within the U.S. Hispanic population, according to a report published online Oct. 4 in CA: A Cancer Journal for Clinicians.

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Childhood Risk Profiles Affect Middle-Age Lung Function

THURSDAY, Oct. 4, 2018 (HealthDay News) -- Profiles of childhood respiratory risk factors predict middle-age lung function levels and chronic obstructive pulmonary disease (COPD) risk, according to a study published in the September issue of the Annals of the American Thoracic Society.

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Residual Vein Obstruction Down With Compression After DVT

THURSDAY, Oct. 4, 2018 (HealthDay News) -- The likelihood of residual vein obstruction (RVO) is reduced with immediate compression after diagnosis of deep vein thrombosis, according to a study published online Sept. 24 in Blood.

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FDA Seizes Documents From E-Cigarette Maker JUUL

THURSDAY, Oct. 4, 2018 (HealthDay News) -- Thousands of pages of documents were seized from the electronic cigarette (e-cigarette) maker JUUL by the U.S. Food and Drug Administration during a surprise inspection last week as part of the agency's investigation into the company's marketing practices.

CNBC Article
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JUUL Laboratories Have Largest Market Share of E-Cigarettes

WEDNESDAY, Oct. 3, 2018 (HealthDay News) -- From 2016 to 2017, sales of electronic cigarettes (e-cigarettes) by JUUL Laboratories increased 641 percent, with their sales comprising 29 percent of total e-cigarette sales by December 2017, according to a research letter published in the Oct. 2 issue of the Journal of the American Medical Association.

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CDC: Salmonella Outbreak Linked to Gravel Ridge Farms Eggs

WEDNESDAY, Oct. 3, 2018 (HealthDay News) -- The multistate Salmonella outbreak linked to Gravel Ridge Farms cage-free large eggs has grown, and consumers, restaurants, and retailers should not eat, serve, or sell the eggs, the U.S. Centers for Disease Control and Prevention says.

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Red Tide May Be Cause of Florida Beachgoers' Breathing Problems

WEDNESDAY, Oct. 3, 2018 (HealthDay News) -- Red tide may be the reason why some beachgoers on Florida's Atlantic coast have suffered breathing problems, according to Palm Beach County officials.

CBS/AP News Article

Increasing Water Intake Can Cut Cystitis Recurrence

WEDNESDAY, Oct. 3, 2018 (HealthDay News) -- For women at high risk for cystitis recurrence who drink low volumes of fluid daily, increasing water intake prevents recurrence, according to a study published online Oct. 1 in JAMA Internal Medicine.

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Medicare Patient Readmit Rates Higher in Proprietary Hospitals

WEDNESDAY, Oct. 3, 2018 (HealthDay News) -- Among Medicare patients with six major diseases, readmission rates are higher for those receiving care in proprietary hospitals compared with government or nonprofit hospitals, according to a study published online Sept. 18 in PLOS ONE.

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Elevated Blood Pressure Linked to Aortic Valve Disease

WEDNESDAY, Oct. 3, 2018 (HealthDay News) -- Long-term exposure to elevated blood pressure (BP) is associated with increased risk for aortic valve stenosis (AS) and aortic regurgitation (AR), according to a study published online Sept. 12 in the European Heart Journal.

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Family History Linked to Early-Onset A-Fib in Minorities

WEDNESDAY, Oct. 3, 2018 (HealthDay News) -- Probands of African or Hispanic/Latino descent with early-onset atrial fibrillation (EOAF) are more likely than European Americans to have a first-degree relative with AF, according to a study published online Sept. 21 in JAMA Network Open.

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Uninsured Rate at 8.8 Percent in First Quarter of 2018

WEDNESDAY, Oct. 3, 2018 (HealthDay News) -- In the first quarter of 2018, the uninsured rate was 8.8 percent, not significantly different from a year earlier, according to a report released Aug. 29 by the National Center for Health Statistics (NCHS).

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Opioid-Related Hospital Use Up in Elderly Adults

WEDNESDAY, Oct. 3, 2018 (HealthDay News) -- Rates of opioid-related prescriptions and health care utilization are rising among seniors, according to two September statistical briefs released by the Agency for Healthcare Research and Quality (AHRQ). The reports relied on data from the Healthcare Cost and Utilization Project and the Medical Expenditure Panel Survey.

Abstract/Full Text - Weiss
Abstract/Full Text - Moriya and Miller

Southern Dietary Pattern Mediates Racial Difference in HTN

TUESDAY, Oct. 2, 2018 (HealthDay News) -- For black men and women, the Southern dietary pattern is the largest mediating factor for differences in the incidence of hypertension, according to a study published in the Oct. 2 issue of the Journal of the American Medical Association.

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Preventable Cardiovascular Events Are Big Economic Burden

TUESDAY, Oct. 2, 2018 (HealthDay News) -- Preventable cardiovascular events place a considerable health and economic burden on the United States, according to research published in the Sept. 7 issue of the U.S. Centers for Disease Control and Prevention (CDC) Morbidity and Mortality Weekly Report.

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For Employer-Based Plans, Spending Across Services Steady

TUESDAY, Oct. 2, 2018 (HealthDay News) -- Despite large health policy changes, the distribution of spending across service areas has remained fairly consistent over the past 10 years for those enrolled in employer-sponsored insurance, according to a study published in the October issue of Health Affairs.

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Voluntary Recall of Robaxin 750 mg Due to Dosage Misprint

TUESDAY, Oct. 2, 2018 (HealthDay News) -- Endo Pharmaceuticals is voluntarily recalling two lots of Robaxin (methocarbamol tablets) 750 mg tablets (100-count bottles) due to incorrect dosage information.

Endo Press Release
FDA Recall Notice

Negligible Drop in Neoplastic Lesion Dx After First Round of FIT

TUESDAY, Oct. 2, 2018 (HealthDay News) -- After the first round of a fecal immunochemical test (FIT)-based, multiple-round, long-term screening program, there is a negligible reduction in detection rates for neoplastic lesions in the proximal versus the distal colon, according to a study published online Oct. 2 in the Annals of Internal Medicine.

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Telemedicine RTI Visits Shorter When Antibiotic Prescribed

TUESDAY, Oct. 2, 2018 (HealthDay News) -- In a direct-to-consumer (DTC) telemedicine setting, respiratory tract infection (RTI) encounters in which antibiotics are prescribed are shorter than other encounters, according to a research letter published online Oct. 2 in the Annals of Internal Medicine.

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Alternative Medicines May Aid in the Treatment of Psoriasis

TUESDAY, Oct. 2, 2018 (HealthDay News) -- Some complementary and alternative medicines (CAMs) may be helpful in the treatment of psoriasis, according to a review published online Sept. 5 in JAMA Dermatology.

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Number of Health-Related Data Breaches Increasing

TUESDAY, Oct. 2, 2018 (HealthDay News) -- The number of health data breaches has steadily increased since 2010, according to a research letter published in the Sept. 25 issue of the Journal of the American Medical Association.

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Interviews Can Help Ensure Physician Candidates Fit Culture

TUESDAY, Oct. 2, 2018 (HealthDay News) -- In preparing to interview to hire a new physician, practices must understand their own cultures, according to an article published in Medical Economics.

Abstract/Full Text

FDA Approves New Drug for Antibiotic-Resistant Lung Disease

MONDAY, Oct. 1, 2018 (HealthDay News) -- Arikayce (amikacin liposome inhalation suspension) has been approved by the U.S. Food and Drug Administration to treat lung disease caused by Mycobacterium avium complex (MAC) bacteria among patients who do not respond to conventional therapies, the FDA said in a news release.

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WHO: 'Very High Risk' That Ebola Will Spread From Congo

MONDAY, Oct. 1, 2018 (HealthDay News) -- There is a "very high" risk that the latest Ebola outbreak in Congo will spread beyond that nation's borders, the World Health Organization warns.

AP News Article
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First Human Case of Rat Strain of Hepatitis E Seen in Hong Kong

MONDAY, Oct. 1, 2018 (HealthDay News) -- The first human case of a strain of hepatitis E previously found only in rats was diagnosed in a Hong Kong man who received a liver transplant in May 2017.

The New York Times Article

Hospital Privacy Curtains Become Increasingly Contaminated

MONDAY, Oct. 1, 2018 (HealthDay News) -- Curtains surrounding patient beds become progressively contaminated with bacteria, according to a study published in the September issue of the American Journal of Infection Control.

Abstract/Full Text

More Non-Elderly Americans Uninsured in 2017 Versus 2016

MONDAY, Oct. 1, 2018 (HealthDay News) -- From 2016 to 2017, there was an increase in the number of uninsured non-elderly Americans, according to a report published by the Robert Wood Johnson Foundation.

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Readmission, Death Risk Higher in COPD With Comorbidities

MONDAY, Oct. 1, 2018 (HealthDay News) -- Patients with chronic obstructive pulmonary disease (COPD) who have comorbidities are more likely to experience readmission or mortality and less likely to receive beneficial treatments, according to a study published in the September issue of the Annals of the American Thoracic Society.

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Mental Health Disparities ID'd Among Students of Color

MONDAY, Oct. 1, 2018 (HealthDay News) -- College students of color have lower mental health-related treatment use relative to white students, according to a study published in the September issue of the Journal of Adolescent Health.

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Factors Associated With Phantom Odor Identified

MONDAY, Oct. 1, 2018 (HealthDay News) -- Phantom odor perception in middle-aged and older individuals is associated with poor health, persistent dry mouth, and head injury, according to a study published online Aug. 16 in JAMA Otolaryngology-Head & Neck Surgery.

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Risk of Venous Thromboembolism Recurrence High

MONDAY, Oct. 1, 2018 (HealthDay News) -- The risk of recurrence after incident venous thromboembolism is high, particularly among patients with cancer-related venous thromboembolism, according to a study published in the September issue of The American Journal of Medicine.

Abstract/Full Text

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