See What HealthDay Can Do For You
Contact Us

September 2016 Briefing - Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for September 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Platelet Transfusion Has Minimal Effect for Reversing Ticagrelor

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Autologous platelet transfusion 24 or 48 hours after ticagrelor-mediated platelet inhibition has minimal effect, while a small reversing effect is seen for transfusion after clopidogrel, according to a study published online Sept. 22 in the Journal of Thrombosis and Haemostasis.

Abstract
Full Text (subscription or payment may be required)

CDC: Too Many Health Care Workers Not Getting Flu Vaccine

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Roughly one in every five American health care workers do not receive the annual influenza vaccination, and in some facilities that number exceeds half, according to research published in the Sept. 30 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text

Early Mobilization Improves Outcomes, LOS in Surgical ICUs

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Early mobilization benefits surgical intensive care unit (ICU) patients, according to a study published in the Oct. 1 issue of The Lancet.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Risk of Frailty Associated With Changes in Oral Function

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Aging is tied to changes in oral function, according to a study published online Sept. 22 in the Journal of the American Geriatrics Society.

Full Text (subscription or payment may be required)

Continuous Glucose Monitors Recommended in T1DM

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Continuous glucose monitors are recommended for adults with type 1 diabetes, according to guidelines published online Sept. 2 in the Journal of Clinical Endocrinology and Metabolism.

Abstract
Full Text

Lung Cancer Decision Aids Are Helpful for Patients

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Outpatients find lung cancer screening decision aids helpful, according to a study published online Sept. 21 in the Annals of the American Thoracic Society.

Full Text (subscription or payment may be required)

Upper Functional GI Disorders Often Overlap With IBS

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Factors associated with the overlap of upper functional gastrointestinal disorders (FGIDs) with irritable bowel syndrome (IBS) have been identified, according to a study published in the September issue of the Journal of Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

One in Five With Non-Valvular A-Fib Receiving Digoxin

FRIDAY, Sept. 30, 2016 (HealthDay News) -- About one in five patients with non-valvular atrial fibrillation (NVAF) receives digoxin, with the indication for use considered inappropriate in nearly 60 percent, according to a study published online Sept. 27 in the Journal of Clinical Pharmacy and Therapeutics.

Abstract
Full Text (subscription or payment may be required)

Rapid, Successful Response to ART for Many Patients With HIV

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Many HIV-infected patients have rapid and successful immune and virological response to antiretroviral therapy (ART), according to a study published online Sept. 27 in the Journal of Clinical Pharmacy and Therapeutics.

Abstract
Full Text (subscription or payment may be required)

CDC Concerned About Falling Flu Vaccination Rates

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Influenza vaccination coverage declined 1.5 percent across the entire U.S. population during the 2015-2016 flu season, with only 46 percent of Americans receiving the annual vaccine, the U.S. Centers for Disease Control and Prevention announced Thursday.

More Information

Meditation Recommended for Helping Attendings 'Attend'

FRIDAY, Sept. 30, 2016 (HealthDay News) -- Meditation can allow attending physicians to be "in attendance" in order to heal and maintain personal well-being, according to an article published by the American Medical Association.

More Information

Prescribed NSAIDs Tied to Higher Heart Failure Risk

THURSDAY, Sept. 29, 2016 (HealthDay News) -- Use of prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) may be tied to a higher risk of heart failure, according to research published online Sept. 28 in The BMJ.

Full Text
Editorial

Dose-Dependent Link Between Cannabis Use, Psychosis Relapse

THURSDAY, Sept. 29, 2016 (HealthDay News) -- Cannabis use may raise the risk of psychosis relapse, according to a study published online Sept. 28 in JAMA Psychiatry.

Abstract
Full Text

Systolic Blood Pressure Variability Linked to Mortality, Morbidity

THURSDAY, Sept. 29, 2016 (HealthDay News) -- Systolic blood pressure variability (SBPV) is associated with mortality, coronary heart disease (CHD), stroke, and end-stage renal disease (ESRD), according to a study published in the Sept. 27 issue of the Journal of the American College of Cardiology.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Radiation Effect on Epigenetic Modifiers May Up Metabolic Risk

THURSDAY, Sept. 29, 2016 (HealthDay News) -- Total body irradiation alters intracellular signaling and epigenetic pathways regulating cell proliferation and differentiation of skeletal muscle and adipose progenitor cells, according to an experimental study published online Sept. 20 in Diabetes.

Full Text (subscription or payment may be required)

Capping Copays Will Raise Premiums, Up Drug Prices

THURSDAY, Sept. 29, 2016 (HealthDay News) -- The proposed capping of copays will raise premiums and is likely to increase drug prices, according to a report from the National Center for Policy Analysis (NCPA).

More Information

Constitutional Symptoms Often Trigger Antibiotic Rx in Elderly

THURSDAY, Sept. 29, 2016 (HealthDay News) -- Constitutional symptoms, including mentation, often lead to diagnostic testing and potentially inappropriate antibiotic prescribing in older patients suspected of having a urinary tract infection (UTI) or pneumonia, according to a study published online Sept. 22 in the Journal of the American Geriatrics Society.

Abstract
Full Text (subscription or payment may be required)

Resistance Interval Training Improves Endothelial Function

THURSDAY, Sept. 29, 2016 (HealthDay News) -- Resistance interval training (R-INT) is associated with improved endothelial function, especially in patients with type 2 diabetes (T2D), according to a study published online Sept. 16 in the American Journal of Physiology-Heart and Circulatory Physiology.

Full Text (subscription or payment may be required)

Considerable Number of Doctors Attend Patient Funerals

THURSDAY, Sept. 29, 2016 (HealthDay News) -- A considerable proportion of doctors attend patient funerals, including 71 percent of general practitioners (GPs), according to a study published online Sept. 9 in Death Studies.

Full Text (subscription or payment may be required)

Many Doctors Reluctant to Reveal Mental Health Issues

WEDNESDAY, Sept. 28, 2016 (HealthDay News) -- Wary of the stigma of a mental health diagnosis and its toll on their careers, physicians often avoid getting help for depression and other mental illnesses, according to a report published online Sept. 15 in General Hospital Psychiatry.

Full Text (subscription or payment may be required)

No Long-Term Health Issues for Infants With Isolated Oral Clefts

WEDNESDAY, Sept. 28, 2016 (HealthDay News) -- Infants born with cleft lip, with or without cleft palate, have no greater risk for long-term adverse health outcomes, according to a study published online Sept. 27 in JAMA Pediatrics.

Abstract
Full Text
Editorial (subscription or payment may be required)

T2DM Predicts Mortality in Patients With Heart Failure

WEDNESDAY, Sept. 28, 2016 (HealthDay News) -- For patients with heart failure, the presence of type 2 diabetes mellitus (T2DM) predicts mortality, regardless of the presence of ischemic heart disease (IHD), according to a study published in the Sept. 27 issue of the Journal of the American College of Cardiology.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Unmet Needs for Non-HIV Care in Men Who Have Sex With Men

WEDNESDAY, Sept. 28, 2016 (HealthDay News) -- For men who have sex with men (MSM) and are receiving HIV medical care, the most prevalent unmet needs are for non-HIV medical care services, according to a report published in the Sept. 23 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text

Hatha Yoga Shows Promise in Treating Anxiety

WEDNESDAY, Sept. 28, 2016 (HealthDay News) -- Hatha yoga is a promising method for treating anxiety, but additional research is needed, according to a review published in the August issue of the Journal of Evidence-Based Medicine.

Abstract
Full Text (subscription or payment may be required)

Changes in Use of Glucose-Lowering Drugs From 2006-2013

WEDNESDAY, Sept. 28, 2016 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), the use of glucose-lowering drugs changed from 2006 to 2013, but glycemic control has not changed, according to a study published online Sept. 22 in Diabetes Care.

Full Text (subscription or payment may be required)

Reviewers More Likely to Accept Single-Blind Manuscripts

WEDNESDAY, Sept. 28, 2016 (HealthDay News) -- Reviewers are more likely to accept manuscripts when author names and institutions are visible, even in the presence of errors in the manuscript, according to a study published in the Sept. 27 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required)

Readmission Reduction Program Successful in Safety-Net Hospitals

WEDNESDAY, Sept. 28, 2016 (HealthDay News) -- Medicare's Hospital Readmissions Reduction Program (HRRP) has reduced 30-day readmissions at safety-net hospitals, according to a study published in the September issue of Health Affairs.

Abstract
Full Text

Improved Adult Lung Function Linked to Childhood Farm Life

TUESDAY, Sept. 27, 2016 (HealthDay News) -- Growing up on a farm might be beneficial to lung function, and early-life farm exposure is associated with reduced risk of allergies and asthma later in life, according to a study published online Sept. 26 in Thorax.

Abstract
Full Text

Both Statin, Non-Statin Therapies Effective for Lowering LDL

TUESDAY, Sept. 27, 2016 (HealthDay News) -- Treatments other than statins also can effectively reduce cardiovascular risk, according to a review and meta-analysis published in the Sept. 27 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)

More Evidence of Abdominal Fat, Poor Cardiovascular Health Link

TUESDAY, Sept. 27, 2016 (HealthDay News) -- Visceral adipose tissue -- particularly in the abdominal region -- may indicate increased risk for cardiovascular disease, and lower fat density may equal higher risk, according to a study published in the Oct. 4 issue of the Journal of the American College of Cardiology.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Gliptin Treatment Tied to Higher Risk of Acute Pancreatitis

TUESDAY, Sept. 27, 2016 (HealthDay News) -- Gliptin treatment is associated with increased acute pancreatitis risk, according to research published online Sept. 22 in Diabetes Care.

Full Text (subscription or payment may be required)

Little to No Benefit Found for Colonoscopy After Age 75

TUESDAY, Sept. 27, 2016 (HealthDay News) -- A colonoscopy may not provide much colorectal cancer (CRC) prevention benefit after the age of 75, according to a study published online Sept. 27 in the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

Disabling Injury, Illness Less Likely for Elderly Who Exercise

TUESDAY, Sept. 27, 2016 (HealthDay News) -- Elderly adults who regularly exercise are less likely to suffer a disabling injury or illness, and recover more quickly if they do, according to a study published online Sept. 27 in the Annals of Internal Medicine.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Number of COPD Cases Expected to Increase Through 2030

TUESDAY, Sept. 27, 2016 (HealthDay News) -- The number of chronic obstructive pulmonary disease (COPD) cases is expected to increase through 2030, with the greatest increase anticipated for those aged 75 years and older, according to research published online Sept. 4 in the American Journal of Respiratory and Critical Care Medicine.

Full Text (subscription or payment may be required)

Mercury Exposure Cancels Cognitive Benefits of Exercise

TUESDAY, Sept. 27, 2016 (HealthDay News) -- In young Faroese adults, aerobic fitness is associated with short-term memory and processing speed, and the correlation is attenuated by prenatal methylmercury exposure, according to a study published online Sept. 9 in Environmental Health Perspectives.

Abstract
Full Text

Achieving Optimal Medical Tx Before PCI Beneficial in CAD

TUESDAY, Sept. 27, 2016 (HealthDay News) -- In patients with coronary artery disease (CAD), achievement of optimal medical therapy (OMT) before implantation of a drug-eluting stent significantly reduces subsequent cardiac events, according to a study published in the Sept. 15 issue of The American Journal of Cardiology.

Abstract
Full Text (subscription or payment may be required)

AMA: Practicing Empathy May Lead to More Joy in Medicine

MONDAY, Sept. 26, 2016 (HealthDay News) -- Empathetic listening can help physicians navigate difficult situations and forge deeper connections with patients, leading to greater professional satisfaction and joy, according to the American Medical Association.

More Information

Increased HIV Testing Among Men Who Have Sex With Men

MONDAY, Sept. 26, 2016 (HealthDay News) -- There seems to be a trend toward increased HIV testing and earlier HIV diagnosis among men who have sex with men (MSM), according to a report published in the Sept. 23 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text

Insulin Glargine, Lixisenatide Combo Beneficial in T2DM

MONDAY, Sept. 26, 2016 (HealthDay News) -- For patients with inadequately controlled, basal insulin-treated type 2 diabetes, a novel, titratable, fixed-ratio combination of insulin glargine (iGlar) and lixisenatide (iGlarLixi) is associated with improvements in glycemic control and reduced body weight, according to a study published online Sept. 20 in Diabetes Care.

Full Text (subscription or payment may be required)

European, American Guidelines Lead to Different Recs for Statins

MONDAY, Sept. 26, 2016 (HealthDay News) -- European and American guidelines lead to different recommendations for statin therapy, according to a study published online Sept. 21 in JACC: Cardiovascular Imaging.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Anxiety Disorders Important in ESRD Treated With Hemodialysis

MONDAY, Sept. 26, 2016 (HealthDay News) -- Anxiety disorders are an important clinical problem in patients with end-stage renal disease (ESRD) treated with hemodialysis (HD), according to a review published online Sept. 22 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)

Early TIPS Beneficial in Acute Esophageal Variceal Bleeding

MONDAY, Sept. 26, 2016 (HealthDay News) -- For patients presenting with acute esophageal variceal bleeding (EVB), early transjugular intrahepatic portosystemic shunt (TIPS) is associated with reductions in in-hospital rebleeding and mortality, with no increase in hepatic encephalopathy, according to a study published online Sept. 14 in the Journal of Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

ICU Physicians Use Variety of Techniques to Cope With Fatigue

MONDAY, Sept. 26, 2016 (HealthDay News) -- A variety of cognitive and lifestyle strategies are employed by intensive care unit (ICU) physicians to prevent and cope with fatigue, according to a study published in the September issue of the Annals of the American Thoracic Society.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Orthogeriatric Model of Care Cost-Effective in Elderly With Hip Fx

MONDAY, Sept. 26, 2016 (HealthDay News) -- For 83-year-old patients with hip fracture, an orthogeriatric (OG) model of care is effective and cost-effective, according to research published online Sept. 16 in the Journal of Bone and Mineral Research.

Abstract
Full Text (subscription or payment may be required)

Promising Results for Laughter-Based Exercise Program

FRIDAY, Sept. 23, 2016 (HealthDay News) -- For older adults, combining simulated laughter exercises with a moderate-intensity strength, balance, and flexibility physical activity program is associated with improvements in health, physical performance, and self-efficacy for exercise, according to a study published online Aug. 4 in The Gerontologist.

Abstract
Full Text (subscription or payment may be required)

Deep Brain Stimulation May Improve TBI Symptoms

FRIDAY, Sept. 23, 2016 (HealthDay News) -- Deep brain stimulation (DBS) may help patients with traumatic brain injury gain more independence, according to a study published recently in Neurosurgery.

Full Text (subscription or payment may be required)

Drug-Resistant Bacteria Live in America's Water Systems

FRIDAY, Sept. 23, 2016 (HealthDay News) -- The thousands of miles of aging, corroding pipes that bring water to Americans each day may be home to drug-resistant bacteria, according to a report published online Sept. 12 in the Journal of Public Health Policy.

Full Text (subscription or payment may be required)

Standard and Double Dose Pantoprazole Equally Effective

FRIDAY, Sept. 23, 2016 (HealthDay News) -- For patients with gastric adenoma or early gastric cancer, standard dose or double dose intravenous pantoprazole for 48 hours is equally effective for prevention of delayed bleeding after endoscopic resection, according to a study published online Sept. 16 in the Journal of Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

Most U.S. CKD Patients Receive Renal Replacement Therapy

FRIDAY, Sept. 23, 2016 (HealthDay News) -- Most U.S. patients with advanced chronic kidney disease receive renal replacement therapy (RRT), according to a study published online Sept. 22 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Social Support Intervention Helps Those Living With HIV/AIDS

FRIDAY, Sept. 23, 2016 (HealthDay News) -- A social support intervention can improve social support and quality of life (QOL) for individuals living with HIV/AIDS, according to a study published online Sept. 20 in the Journal of Clinical Nursing.

Abstract
Full Text (subscription or payment may be required)

Pregabalin Benefits Not Linked to Prior Gabapentin Use

FRIDAY, Sept. 23, 2016 (HealthDay News) -- Pregabalin is beneficial for neuropathic pain, regardless of previous gabapentin use, according to research published online Sept. 9 in Pain Practice.

Abstract
Full Text (subscription or payment may be required)

Animal Study Finds DNA-Based Vaccine Effective Against Zika

THURSDAY, Sept. 22, 2016 (HealthDay News) -- An experimental DNA-based vaccine for Zika virus has proceeded to human safety trials, according to findings published online Sept. 22 in Science.

Full Text (subscription or payment may be required)

Effectiveness of Tobacco Taxation Is Being Undermined

THURSDAY, Sept. 22, 2016 (HealthDay News) -- The effectiveness of tobacco taxation is being undermined by smokers' behavioral changes and tobacco industry promotions, according to a health policy brief published online Sept. 19 in Health Affairs.

Full Text

Tofacitinib Citrate May Stimulate Hair Regrowth in Alopecia Areata

THURSDAY, Sept. 22, 2016 (HealthDay News) -- A drug used for rheumatoid arthritis might regrow hair in alopecia areata (AA) patients, according to a study published online Sept. 22 in JCI Insight.

Full Text

CDC: Falls Leading Cause of Injury, Death in U.S. Seniors

THURSDAY, Sept. 22, 2016 (HealthDay News) -- Falls are the leading cause of injury and death among older people in the United States, according to research published in the Sept. 23 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text

Changes in Blood Microbiota in Obese With Liver Fibrosis

THURSDAY, Sept. 22, 2016 (HealthDay News) -- In obese patients, changes in blood microbiota are associated with liver fibrosis, according to a study published online Sept. 17 in Hepatology.

Abstract
Full Text (subscription or payment may be required)

CCTA Has Prognostic Value in Asymptomatic T2DM Patients

THURSDAY, Sept. 22, 2016 (HealthDay News) -- For asymptomatic patients with type 2 diabetes, coronary computed tomographic angiography (CCTA) has prognostic value, with excellent long-term prognoses for those with normal coronary arteries and non-obstructive coronary artery disease (CAD), according to a study published online Sept. 14 in JACC: Cardiovascular Imaging.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Smoking Appears to Have Broad, Long-Lasting Impact on DNA

WEDNESDAY, Sept. 21, 2016 (HealthDay News) -- Smoking cigarettes can leave a lasting imprint on human DNA, altering more than 7,000 genes in ways that may contribute to the development of smoking-related diseases, according to research published online Sept. 20 in Circulation: Cardiovascular Genetics.

Abstract
Full Text (subscription or payment may be required)

FTO Gene Does Not Inhibit Weight Loss Success

WEDNESDAY, Sept. 21, 2016 (HealthDay News) -- Patients with the FTO gene respond to weight-loss strategies as well as those without the gene, according to research published online Sept. 20 in The BMJ.

Full Text
Editorial

Economic Burden of U.S. Opioid Epidemic $78.5 Billion Annually

WEDNESDAY, Sept. 21, 2016 (HealthDay News) -- Abuse of opioids costs the U.S. economy $78.5 billion a year, according to a study published in the October issue of Medical Care.

Full Text
Editorial (subscription or payment may be required)

Stress May Compromise Health Benefits of Eating 'Good' Fats

WEDNESDAY, Sept. 21, 2016 (HealthDay News) -- Stressful events from the day before appear to eradicate any health benefits a person might have gained from choosing a breakfast rich in monounsaturated fats, as opposed to a breakfast loaded with saturated fats, according to research published online Sept. 20 in Molecular Psychiatry.

Abstract
Full Text (subscription or payment may be required)

NIH: More Must Be Done to Fight Antimicrobial Resistance

WEDNESDAY, Sept. 21, 2016 (HealthDay News) -- Antimicrobial resistance (AMR) remains a major public health threat, and only a multipronged attack can address the problem, according to a report published in the Sept. 20 issue of the Journal of the American Medical Association.

Abstract
Full Text

Non-TNF Biologic Beats Second Anti-TNF in Rheumatoid Arthritis

WEDNESDAY, Sept. 21, 2016 (HealthDay News) -- A non-tumor necrosis factor (TNF)-targeted biologic is more effective than a second anti-TNF drug for treatment of rheumatoid arthritis in patients with insufficient response to a first anti-TNF drug, according to a study published in the Sept. 20 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)

Physicians Treating Few Patients With Buprenorphine

WEDNESDAY, Sept. 21, 2016 (HealthDay News) -- For buprenorphine prescribers, the monthly patient census is 13 patients, according to a research letter published in the Sept. 20 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required)

Quality of Diet Linked to Risk of T2DM Regardless of BMI Change

WEDNESDAY, Sept. 21, 2016 (HealthDay News) -- Changes in diet quality correlate with subsequent risk of type 2 diabetes, and the association between diet quality changes and diabetes risk is only partly explained by body weight changes, according to a study published online Sept. 15 in Diabetes Care.

Full Text (subscription or payment may be required)

Research Reveals 2 Genetic Loci Linked to Acute Kidney Injury

WEDNESDAY, Sept. 21, 2016 (HealthDay News) -- Four single-nucleotide polymorphisms at two loci that are associated with acute kidney injury have been identified, according to a study published online Aug. 30 in the American Journal of Respiratory and Critical Care Medicine.

Full Text (subscription or payment may be required)

New Mosquito-Borne Virus Detected in 8-Year-Old in Haiti

TUESDAY, Sept. 20, 2016 (HealthDay News) -- Another mosquito-borne virus may be starting to circulate in the Caribbean, according to findings published online recently in the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

Full Text

H1N1 Vaccine Not Associated With Congenital Malformations

TUESDAY, Sept. 20, 2016 (HealthDay News) -- The vaccine against the H1N1 strain of influenza doesn't appear to be linked to congenital malformations, according to research published online Sept. 20 in the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

No Link Found Between Vasectomy, Prostate Cancer Risk

TUESDAY, Sept. 20, 2016 (HealthDay News) -- There is no connection between vasectomy and overall risk of prostate cancer or prostate cancer mortality, according to a study published online Sept. 19 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

CDC: Prescribing of Antibiotics in U.S. Hospitals Still Too High

TUESDAY, Sept. 20, 2016 (HealthDay News) -- Despite growing concerns about creating drug-resistant bacteria, overprescribing of antibiotics in U.S. hospitals didn't drop between 2006 and 2012, according to a new federal report published online Sept. 19 in JAMA Internal Medicine.

Abstract
Full Text
Editorial (subscription or payment may be required)

Diabetes Risk Higher in Canada's First Nations People

TUESDAY, Sept. 20, 2016 (HealthDay News) -- Diabetes is more widespread among descendants of Canada's First Nations people than among the general population, according to a study published online Sept. 19 in CMAJ, the journal of the Canadian Medical Association.

Abstract
Full Text

Hospitals Increasingly Employing Doctors, Effects on Care Uncertain

TUESDAY, Sept. 20, 2016 (HealthDay News) -- Hospitals are increasingly switching to an employment relationship with physicians, but switching has had no impact on primary composite quality metrics, according to a study published online Sept. 20 in the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

Gemigliptin, Metformin Combo Beats Monotherapy in T2DM

TUESDAY, Sept. 20, 2016 (HealthDay News) -- Gemigliptin combined with metformin is superior to monotherapy with either drug for patients with type 2 diabetes mellitus (T2DM), according to a study published online Sept. 13 in Diabetes, Obesity and Metabolism.

Abstract
Full Text (subscription or payment may be required)

Diabetes Ups Risk of Amputation in Critical Limb Ischemia

TUESDAY, Sept. 20, 2016 (HealthDay News) -- For patients with critical limb ischemia (CLI), those with diabetes mellitus (DM) are at increased risk of major amputation, according to a study published online Sept. 9 in Diabetes Care.

Full Text (subscription or payment may be required)

Drop in Use of Digital Rectal Examination, PSA Testing

TUESDAY, Sept. 20, 2016 (HealthDay News) -- Following U.S. Preventive Services Task Force (USPSTF) recommendations against routine prostate-specific antigen (PSA) screening, there has been a decrease in utilization of digital rectal examination and PSA testing, according to a study published in the October issue of The Journal of Urology.

Abstract
Full Text

BNPratio Predicts Mortality in Degenerative Mitral Regurgitation

TUESDAY, Sept. 20, 2016 (HealthDay News) -- The ratio of B-type natriuretic peptide (BNP) to upper limit of normal for age, sex, and assay (BNPratio) predicts long-term mortality for patients with mitral regurgitation (MR) who undergo medical management, according to a study published in the Sept. 20 issue of the Journal of the American College of Cardiology.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

FDA Approves First Drug for Duchenne Muscular Dystrophy

MONDAY, Sept. 19, 2016 (HealthDay News) -- Exondys 51 (eteplirsen) injection has been approved by the U.S. Food and Drug Administration for certain patients with Duchenne muscular dystrophy (DMD). It is the first drug to gain FDA approval for the condition.

More Information

Playing Pokémon GO Leading to Increase in Distracted Driving

MONDAY, Sept. 19, 2016 (HealthDay News) -- Pokémon GO is becoming a dangerous distraction for drivers, according to a research letter published online Sept. 16 in JAMA Internal Medicine.

Full Text

Most Patients Prefer Oral Dual Therapy in Chronic Hepatitis C

MONDAY, Sept. 19, 2016 (HealthDay News) -- For patients with chronic hepatitis C (CHC), most prefer oral therapy with sofosbuvir (SOF) and ribavirin (RBV) versus triple therapy involving pegylated interferon (PegIFN), according to a study published online Sept. 14 in the Journal of Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

IL-32 Has Inflammatory Properties in Human Obesity

MONDAY, Sept. 19, 2016 (HealthDay News) -- Interleukin (IL)-32 has inflammatory and remodeling properties in human obesity, according to a study published online Sept. 14 in Diabetes.

Full Text (subscription or payment may be required)

Average Premiums for Health Care Coverage Stable in 2016

MONDAY, Sept. 19, 2016 (HealthDay News) -- The average annual premiums for single and family coverage remained stable in 2016, according to a study published online Sept. 14 in Health Affairs.

Abstract
Full Text

Readmit Predictors for Congenital Heart Disease Are Lesion Specific

MONDAY, Sept. 19, 2016 (HealthDay News) -- For adults with congenital heart disease, readmission is more likely among those with a primary diagnosis of congestive heart failure, and predictors of readmission are lesion specific, according to a study published online Sept. 13 in Circulation: Cardiovascular Quality and Outcomes.

Abstract
Full Text (subscription or payment may be required)

Guidelines Developed for Lymphangioleiomyomatosis

FRIDAY, Sept. 16, 2016 (HealthDay News) -- Evidence-based guidelines have been developed for the diagnosis and treatment of lymphangioleiomyomatosis (LAM). The clinical practice guidelines were published online Sept. 15 in the American Journal of Respiratory and Critical Care Medicine.

Full Text (subscription or payment may be required)

Medical Marijuana Laws Linked to Reduced Opioid Use, Abuse

FRIDAY, Sept. 16, 2016 (HealthDay News) -- A new study of drivers who died in auto accidents suggests people in states with medical marijuana laws may be using fewer opioids, according to a study published online Sept. 15 in the American Journal of Public Health.

Full Text (subscription or payment may be required)

Tighter Systolic BP Control Could Save 100K U.S. Lives Annually

FRIDAY, Sept. 16, 2016 (HealthDay News) -- Engaging Americans at high risk for cardiovascular disease in aggressive efforts to lower their systolic blood pressure could save more than 100,000 lives a year, according to a study presented at the American Heart Association's Council on Hypertension 2016 Scientific Sessions, held from Sept. 14 to 17 in Orlando, Fla.

Press Release
More Information

Study Supports Minimal Residual Disease As End Point in Myeloma

FRIDAY, Sept. 16, 2016 (HealthDay News) -- For patients with newly diagnosed multiple myeloma (MM), minimal residual disease (MRD)-negative status is associated with improved survival, according to a meta-analysis published online Sept. 15 in JAMA Oncology.

Abstract
Full Text
Editorial

Evolocumab Safe, Effective for Those With Dysglycemia, MetS

FRIDAY, Sept. 16, 2016 (HealthDay News) -- For patients with or without dysglycemia or metabolic syndrome (MetS), evolocumab is safe and efficacious for reducing low-density lipoprotein cholesterol at 52 weeks, according to research published online Sept. 13 in Diabetes, Obesity and Metabolism.

Abstract
Full Text (subscription or payment may be required)

Testosterone Seems Safe for Hypogonadal Prostate CA Patients

FRIDAY, Sept. 16, 2016 (HealthDay News) -- For hypogonadal men with prostate cancer, testosterone treatment seems oncologically safe, according to a study published in the October issue of The Journal of Urology.

Abstract
Full Text

Nifedipine Not Superior to Placebo for Chronic Chilblains

FRIDAY, Sept. 16, 2016 (HealthDay News) -- For patients with chronic chilblains, nifedipine is not superior to placebo, according to a study published in the September/October issue of the Annals of Family Medicine.

Abstract
Full Text

Recommending Oral Probiotics Doesn't Cut Antibiotic Use

FRIDAY, Sept. 16, 2016 (HealthDay News) -- Advising patients with asthma to take probiotics does not reduce antibiotic use, according to a study published in the September/October issue of the Annals of Family Medicine.

Abstract
Full Text

Early Rx With Losartan Doesn't Slow Kidney Disease Progression

FRIDAY, Sept. 16, 2016 (HealthDay News) -- For American-Indians with type 2 diabetes, early administration of losartan does not slow progression of glomerular filtration rate (GFR) decline, according to a study published online Sept. 9 in Diabetes Care.

Full Text (subscription or payment may be required)

CDC: Many U.S. Adults Over 50 Do Not Exercise Regularly

THURSDAY, Sept. 15, 2016 (HealthDay News) -- More than one-quarter of Americans over 50 don't exercise, increasing their risk for cardiovascular disease, diabetes, and cancer, according to research published in the Sept. 16 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text

Early-Onset Menopause Tied to Increased CVD Events, Mortality

THURSDAY, Sept. 15, 2016 (HealthDay News) -- Women who enter menopause early may be at greater risk for cardiovascular disease and premature death, according to a review published online Sept. 14 in JAMA Cardiology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Hearing Aids Underused by the 'Older Old'

THURSDAY, Sept. 15, 2016 (HealthDay News) -- Although the rate of hearing loss in patients goes up significantly during the 10th decade of life, hearing aids remain underused in this population, according to research published online Sept. 15 in JAMA Otolaryngology-Head & Neck Surgery.

Abstract
Full Text

Experimental Zoster Vaccine Effective in Adults Aged 70+

THURSDAY, Sept. 15, 2016 (HealthDay News) -- An experimental vaccine against herpes zoster may offer lasting protection for most older adults who receive it, according to a study published in the Sept. 15 issue of the New England Journal of Medicine.

Abstract
Full Text
Editorial

Daily Alcohol Intake Linked to Enlarged Left Atrium, A-Fib

THURSDAY, Sept. 15, 2016 (HealthDay News) -- Long-term drinking of even moderate amounts of alcohol may enlarge the left atrium and thereby contribute to atrial fibrillation (AF), according to a study published online Sept. 14 in the Journal of the American Heart Association.

Abstract
Full Text

Experimental Gel Antibiotic May Offer New Otitis Media Rx

THURSDAY, Sept. 15, 2016 (HealthDay News) -- A single application of an antibiotic gel into the ear might one day offer an easier way to treat bacterial otitis media, according to an experimental study published online Sept. 14 in Science Translational Medicine.

Full Text (subscription or payment may be required)

Many Spirometers Used in Primary Care Deemed Inaccurate

THURSDAY, Sept. 15, 2016 (HealthDay News) -- Spirometers used in primary care offices are frequently inaccurate, according to a study published online Sept. 6 in the Annals of the American Thoracic Society.

Full Text (subscription or payment may be required)

Importance of Drug As Assessed by Doctor Not Tied to Adherence

THURSDAY, Sept. 15, 2016 (HealthDay News) -- Physician-assessed drug importance is not associated with patient-reported drug adherence, according to a study published in the September/October issue of the Annals of Family Medicine.

Abstract
Full Text

Lower Citrulline Values With Metformin Treatment in T2DM

THURSDAY, Sept. 15, 2016 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), metformin treatment is associated with lower citrulline values, according to a study published online Sept. 12 in Diabetes.

Full Text (subscription or payment may be required)

Recommendations Developed for Cost-Effectiveness Analyses

THURSDAY, Sept. 15, 2016 (HealthDay News) -- A new set of recommendations has been developed for conduct and reporting of cost-effectiveness analyses, according to a report published in the Sept. 13 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Learning Collaborative Model Cuts Door-to-Needle Times

THURSDAY, Sept. 15, 2016 (HealthDay News) -- A learning collaborative model can reduce door-to-needle (DTN) times in patients with acute ischemic stroke treated with tissue-type plasminogen activator, according to a study published online Sept. 13 in Circulation: Cardiovascular Quality and Outcomes.

Abstract
Full Text (subscription or payment may be required)

Sertraline May Help Prevent Depressive Disorders After TBI

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- Sertraline seems to be efficacious for preventing depressive disorders after traumatic brain injury (TBI), according to a study published online Sept. 14 in JAMA Psychiatry.

Abstract
Full Text (subscription or payment may be required)

Value-Driven Outcomes Tool Can Cut Health Care Costs

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- A multifaceted value-driven outcomes tool that identifies variability in costs and outcomes can reduce health care costs, according to a study published in the Sept. 13 issue of the Journal of the American Medical Association.

Abstract
Full Text
Editorial (subscription or payment may be required)

'Super-Aging' Older Adults Have Younger Looking Brain Regions

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- Key brain regions in mentally sharp "superagers" are similar to those of people much younger, according to a study published in the Sept. 14 issue of The Journal of Neuroscience.

Abstract
Full Text

Many Medicare Patients Non-Adherent to Antihypertensives

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- Nearly five million Medicare prescription drug enrollees aren't taking their antihypertensive medication as directed, according to research published in the Sept. 13 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text

Transition to Public Insurance Ups Post-Heart Transplant Death

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- For patients receiving first-time orthotopic heart transplants, transition from private to public health insurance is associated with increased mortality, according to a study published online Sept. 13 in Circulation: Cardiovascular Quality and Outcomes.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Infective Endocarditis Incidence 1.1 Percent After TAVR

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- For patients undergoing transcatheter aortic valve replacement (TAVR) the incidence of infective endocarditis is 1.1 percent per person-year, according to a study published in the Sept. 13 issue the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)

Pain and Itch Highly Prevalent Months After Herpes Zoster

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- For patients with herpes zoster (HZ), pain and itch are prevalent and pain is associated with quality of life and increased costs, according to a study published online Sept. 9 in Pain Practice.

Abstract
Full Text (subscription or payment may be required)

Sitagliptin Not Linked to Higher Fracture Risk in Diabetes

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- Patients with diabetes often have fractures, but sitagliptin is not associated with increased fracture risk, according to a study published online Sept. 8 in Diabetes, Obesity and Metabolism.

Abstract
Full Text (subscription or payment may be required)

Prediabetes Often Undiagnosed in Women With Prior GDM

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- For women with a history of gestational diabetes mellitus (GDM), having more health visits in the previous year is associated with receiving diabetes screening, according to a study published in the Sept. 8 issue of the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

Full Text

Meta-Analysis: Colchicine Cuts Risk of Pericarditis Recurrence

WEDNESDAY, Sept. 14, 2016 (HealthDay News) -- Colchicine is effective and reduces the risk of pericarditis recurrence/post-pericardiotomy syndrome, according to a meta-analysis published online Aug. 31 in Cardiovascular Therapeutics.

Abstract
Full Text (subscription or payment may be required)

Discrepancies ID'd in Adult CVD Risk Assessment Guidelines

TUESDAY, Sept. 13, 2016 (HealthDay News) -- There are considerable discrepancies in primary prevention guidelines for adult cardiovascular risk assessment, according to a review published online Sept. 13 in the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

Most Patients Taking Opioids Open to Receiving Naloxone Rx

TUESDAY, Sept. 13, 2016 (HealthDay News) -- A new, small survey of patients taking opioids found that most were willing to also fill prescriptions for naloxone. The report was published in the September/October issue of the Annals of Family Medicine.

Abstract
Full Text

Electroacupuncture Helps Ease Chronic Severe Constipation

TUESDAY, Sept. 13, 2016 (HealthDay News) -- Acupuncture may provide some relief to patients with chronic severe functional constipation, according to research published online Sept. 13 in the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

New Anticancer Drugs Up Costs and Life Expectancy Considerably

TUESDAY, Sept. 13, 2016 (HealthDay News) -- New anticancer drugs, which increase costs considerably, are associated with large gains in life expectancy, according to research published in the September issue of Health Affairs.

Abstract
Full Text (subscription or payment may be required)

U-Shaped Link for Fish Consumption, Mortality

TUESDAY, Sept. 13, 2016 (HealthDay News) -- There is a U-shaped correlation between fish consumption and all-cause mortality, according to a study published online Sept. 7 in the Journal of Internal Medicine.

Abstract
Full Text (subscription or payment may be required)

Too Few Diabetes Patients Receiving Statins

TUESDAY, Sept. 13, 2016 (HealthDay News) -- Nearly all middle-aged patients with diabetes should be taking statins, but cardiologists fail to prescribe these medications for two out of every five such patients in their care, according to a study published in the Sept. 20 issue of the Journal of the American College of Cardiology.

Full Text (subscription or payment may be required)

Advanced Glycation End Products Tied to Renal Function Loss

TUESDAY, Sept. 13, 2016 (HealthDay News) -- For American-Indians with type 2 diabetes, advanced glycation end products (AGEs) are associated with renal function loss (RFL), according to a study published online Sept. 8 in Diabetes.

Full Text (subscription or payment may be required)

Similar Outcomes for Permissive Underfeeding, Standard Feeding

TUESDAY, Sept. 13, 2016 (HealthDay News) -- For critically ill adults, permissive underfeeding with full protein intake is associated with similar outcomes as standard feeding among those with high and low nutritional risk, according to research published online Sept. 2 in the American Journal of Respiratory and Critical Care Medicine.

Full Text (subscription or payment may be required)

Metabolic Syndrome and Obesity Up Risk of Mortality in CRC

TUESDAY, Sept. 13, 2016 (HealthDay News) -- For patients with early-stage colorectal cancer (CRC), the presence of metabolic syndrome (MetSyn) and obesity is associated with increased risk of mortality, according to a study published online Sept. 6 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

Review of Evidence Confirms Efficacy of Statin Therapy

MONDAY, Sept. 12, 2016 (HealthDay News) -- Statins are efficacious and safe for reducing the risk of vascular events, according to a review published online Sept. 8 in The Lancet.

Full Text

One in Four Older Adults Report Breathlessness

MONDAY, Sept. 12, 2016 (HealthDay News) -- Twenty-five percent of adults aged 70 years and older report breathlessness, which is associated with higher rates of depression, anxiety, and severe fatigue, according to a study published online Sept. 7 in the Journal of the American Geriatrics Society.

Abstract
Full Text (subscription or payment may be required)

Long-Term Exposure to Air Pollution Ups Insulin Resistance

MONDAY, Sept. 12, 2016 (HealthDay News) -- Long-term exposure to air pollution is associated with insulin resistance (IR) among the general population, according to a study published online Sept. 7 in Diabetes.

Full Text (subscription or payment may be required)

Corticosteroids Linked to Worse Outcome in Facial Palsy

MONDAY, Sept. 12, 2016 (HealthDay News) -- For patients with Lyme disease-associated facial palsy (LDFP), corticosteroid use is associated with worse long-term facial function outcome, according to a study published online Sept. 6 in The Laryngoscope.

Abstract
Full Text (subscription or payment may be required)

Sleep Apnea Diagnoses Up Among Outpatients From 1993 to 2010

MONDAY, Sept. 12, 2016 (HealthDay News) -- From 1993 to 2010 there was an increase in the diagnosis of sleep apnea in U.S. ambulatory practice visits, according to a study published online Sept. 1 in the Annals of the American Thoracic Society.

Full Text (subscription or payment may be required)

Statin Rx May Prevent Myocardial Ischemia-Reperfusion Injury

MONDAY, Sept. 12, 2016 (HealthDay News) -- Postconditioning with rosuvastatin prevents myocardial ischemia-reperfusion injury in a rat model, according to a study published online Aug. 31 in Cardiovascular Therapeutics.

Abstract
Full Text (subscription or payment may be required)

Reports of Fatal Anaphylaxis With IV Iron Products

MONDAY, Sept. 12, 2016 (HealthDay News) -- Fatal anaphylaxis cases have been reported with administration of intravenous (IV) iron products, according to a letter to the editor published online Aug. 29 in the American Journal of Hematology.

Full Text (subscription or payment may be required)

AAA Progression Tied to Higher Plasma D-Dimer Concentration

FRIDAY, Sept. 9, 2016 (HealthDay News) -- Abdominal aortic aneurysm (AAA) progression is positively associated with increasing plasma D-dimer concentration, according to a study published online Aug. 27 in the Journal of Thrombosis and Haemostasis.

Abstract
Full Text (subscription or payment may be required)

Probable PTSD Linked to Bronchodilator Response, Asthma

FRIDAY, Sept. 9, 2016 (HealthDay News) -- Probable posttraumatic stress disorder (PTSD) is associated with bronchodilator response (BDR) and incident asthma, according to a study published online Aug. 22 in the American Journal of Respiratory and Critical care Medicine.

Full Text (subscription or payment may be required)

Pregabalin Significantly Improves Neuropathic Pain

FRIDAY, Sept. 9, 2016 (HealthDay News) -- Pregabalin significantly improves neuropathic pain, irrespective of the time since pain onset, according to a study published online Sept. 2 in Pain Practice.

Abstract
Full Text (subscription or payment may be required)

Liraglutide, Sitagliptin Have No Effect on Renal Hemodynamics

FRIDAY, Sept. 9, 2016 (HealthDay News) -- In insulin-naive patients with type 2 diabetes, 12 weeks of treatment with liraglutide or sitagliptin has no effect on renal hemodynamics, according to a study published online Sept. 1 in Diabetes Care.

Full Text (subscription or payment may be required)

Losartan Reduces Aldosterone in Patients With HTN, Without OSA

FRIDAY, Sept. 9, 2016 (HealthDay News) -- For patients with hypertension and obstructive sleep apnea (OSA), treatment with losartan does not lead to significant reductions in aldosterone, but the treatment is tied to aldosterone reductions in patients with hypertension but without OSA, according to a study published online Aug. 22 in the Annals of the American Thoracic Society.

Full Text (subscription or payment may be required)

High Glycemic Index Diet Raises Hepatic Fat, Glycogen Stores

FRIDAY, Sept. 9, 2016 (HealthDay News) -- A one-week high glycemic index (HGI) diet increases hepatic fat and glycogen stores in healthy adults compared with a low glycemic index (LGI) diet, according to a study published online Sept. 4 in Diabetes, Obesity and Metabolism.

Abstract
Full Text (subscription or payment may be required)

CDC: COPD-Related Mortality Mostly Down in the United States

FRIDAY, Sept. 9, 2016 (HealthDay News) -- Fewer Americans are dying from chronic obstructive pulmonary disease (COPD), but not black women and the middle-aged, according to a September data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

More Information

New Electrical Stimulation Method Ups Dexterity After Stroke

FRIDAY, Sept. 9, 2016 (HealthDay News) -- A new form of electrical stimulation therapy can help restore some dexterity to a hand that's been paralyzed by stroke, according to a study published online Sept. 8 in Stroke.

Abstract
Full Text

Incidence of Hair Removal-Linked Injuries Up From 1991 to 2013

FRIDAY, Sept. 9, 2016 (HealthDay News) -- From 1991 to 2013 there was an increase in the incidence of hair removal-related injuries, with incidence varying with age, according to a study published online Sept. 5 in the Journal of Cosmetic Dermatology.

Abstract
Full Text (subscription or payment may be required)

Intensive T2DM Tx Extends Complication-Free Survival

THURSDAY, Sept. 8, 2016 (HealthDay News) -- Early, intensified intervention in type 2 diabetes patients with microalbuminuria increases life span, with patients more likely free from severe complications, according to a study published online Aug. 16 in Diabetologia.

Full Text

Dexrazoxane Prevents Chemo-Induced Cardiotoxicity

THURSDAY, Sept. 8, 2016 (HealthDay News) -- Dexrazoxane can prevent anthracycline-induced cardiotoxicity and should be used for cardioprotection in children and young adults, according to a review published online Sept. 4 in the British Journal of Clinical Pharmacology.

Abstract
Full Text

PSA Failure Predicts Death in Men With No, Minimal Comorbidity

THURSDAY, Sept. 8, 2016 (HealthDay News) -- Prostate-specific antigen (PSA) failure is associated with increased risk of all-cause mortality for men with intermediate- or high-risk prostate cancer with no or minimal comorbidity, according to a study published online Sept. 6 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

Glycemic Index Poor Indicator of Blood Glucose Response

THURSDAY, Sept. 8, 2016 (HealthDay News) -- Glycemic index values of the same foods can vary widely and may be an unreliable indicator of blood glucose response, according to a study published online Sept. 7 in the American Journal of Clinical Nutrition.

Abstract
Full Text (subscription or payment may be required)

Obesity May Up Survival in Metastatic Renal Cell Carcinoma

THURSDAY, Sept. 8, 2016 (HealthDay News) -- Obesity may increase survival for patients with metastatic renal cell carcinoma (RCC), according to a study published online Sept. 6 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

Study Explores Link Between Weight and Stroke Risk in Women

THURSDAY, Sept. 8, 2016 (HealthDay News) -- Excess weight may put women at increased risk for ischemic stroke, but at lower risk for hemorrhagic stroke, according to research published online Sept. 7 in Neurology.

Abstract
Full Text
Editorial (subscription or payment may be required)

Oral Contraceptives May Be Cause of Drop in Ovarian CA Mortality

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- Ovarian cancer mortality is down dramatically in many parts of the world, and the use of oral contraceptives (OCs) may be a main reason why, according to a study published online Sept. 5 in the Annals of Oncology.

Abstract
Full Text

A-Fib Contributes to Wide Range of Other Health Conditions

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- Atrial fibrillation is associated with a wider range of conditions than previously believed, according to a review and meta-analysis published online Sept. 6 in The BMJ.

Full Text

Free Thyroxine Hormone Levels Linked to Sudden Cardiac Death

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- Higher levels of free thyroxine (FT4) may indicate a greater risk of sudden cardiac death, even if those levels aren't abnormally high, according to a study published in the Sept. 6 issue of Circulation.

Full Text (subscription or payment may be required)

Fan Use in Extreme Heat May Be Detrimental to Health in Elderly

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- When the temperature rises to 108 degrees Fahrenheit or higher, older adults should not use an electric fan, according to a research letter published in the Sept. 6 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required)

White Matter Damage Linked to Cognitive Impairment in CAD

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- In symptomatic carotid artery disease (CAD), subcortical white matter ischemic lesion locations and severity of ultrastructural tract damage contribute to cognitive impairment, according to a study published online Sept. 6 in Radiology.

Abstract
Full Text

Volume of Ascites Positively Associated With Umbilical Hernia

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- For patients with cirrhosis, volume of ascites is positively associated with umbilical hernia, according to a study published online Aug. 29 in the Journal of Evidence-Based Medicine.

Abstract
Full Text (subscription or payment may be required)

TAPS Tool Identifies Problem Substance Use in Primary Care

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- The Tobacco, Alcohol, Prescription medication, and other Substance use (TAPS) tool can detect clinically relevant problem substance use, especially tobacco, alcohol, and marijuana use disorders, according to a study published online Sept. 6 in the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

Saline-Based Nasal Spray Found to Be Effective for Epistaxis

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- A simple saline-based nasal spray is as effective as medicated sprays in controlling epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT), according to a study published in the Sept. 6 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)

Number of Americans Adopting Gluten-Free Diet Increasing

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- The number of Americans following a gluten-free diet tripled between 2009 and 2014, but diagnoses of celiac disease remained stable during that same period, according to a research letter published online Sept. 6 in JAMA Internal Medicine.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Canadian Cardiovascular Society Updates A-Fib Guidelines

TUESDAY, Sept. 6, 2016 (HealthDay News) -- The Canadian Cardiovascular Society has updated guidelines relating to the management of atrial fibrillation (AF); the guidelines were published online Sept. 5 in the Canadian Journal of Cardiology.

Abstract
Full Text (subscription or payment may be required)

Metformin Tied to Cardiovascular Benefits in T1DM Patients

TUESDAY, Sept. 6, 2016 (HealthDay News) -- Metformin may help preserve cardiovascular health in patients with type 1 diabetes, according to a study published online Aug. 26 in Cardiovascular Diabetology.

Full Text

USPSTF Recommends Latent Tuberculosis Infection Screening

TUESDAY, Sept. 6, 2016 (HealthDay News) -- According to a final recommendation statement from the U.S. Preventive Services Task Force (USPSTF) published in the Sept. 6 issue of the Journal of the American Medical Association, high-risk populations should be screened for latent tuberculosis infection (LTBI).

Recommendation Statement
Evidence Review
Editorial

AAFP Downgrades USPSTF CRC Screening Recommendation

TUESDAY, Sept. 6, 2016 (HealthDay News) -- The American Academy of Family Physicians (AAFP) has graded the recommendation for colorectal cancer screening as a B recommendation, in contrast to the U.S. Preventive Services Task Force (USPSTF) grade A recommendation.

More Information

Self-Regulatory Fatigue Linked to QoL in Fibromyalgia Syndrome

TUESDAY, Sept. 6, 2016 (HealthDay News) -- Patients with fibromyalgia syndrome (FMS) with higher self-regulatory fatigue (SRF) have lower quality of life (QoL), according to a study published online Sept. 2 in Pain Practice.

Abstract
Full Text (subscription or payment may be required)

Novel Hepatology Rotation Ups Knowledge of Liver Disease

TUESDAY, Sept. 6, 2016 (HealthDay News) -- A novel non-elective inpatient hepatology rotation increases knowledge of chronic liver disease (CLD) among internal medicine (IM) residents, according to a study published online Aug. 10 in Hepatology.

Abstract
Full Text (subscription or payment may be required)

Fluticasone Furoate/Vilanterol Cuts Exacerbations in COPD

TUESDAY, Sept. 6, 2016 (HealthDay News) -- A combination of fluticasone furoate and vilanterol reduces the rate of moderate or severe exacerbations among patients with chronic obstructive pulmonary disease (COPD), according to a study published online Sept. 4 in the New England Journal of Medicine. The research was published to coincide with the annual European Respiratory Society International Congress, held from Sept. 3 to 7 in London.

Abstract
Full Text
More Information

More Diabetes-Associated, Non-Associated Autoantibodies in T1D

TUESDAY, Sept. 6, 2016 (HealthDay News) -- Patients with type 1 diabetes have more diabetes-associated autoantibodies (DAAs) and non-DAAs than patients with type 2 diabetes, according to a study published online Aug. 29 in Diabetes Care.

Full Text (subscription or payment may be required)

Antidiabetes Prescriptions 15-Fold Higher Than Antiobesity Rx

TUESDAY, Sept. 6, 2016 (HealthDay News) -- The adoption rate of the newest antidiabetes pharmacotherapy, subtype 2 sodium-glucose transport protein inhibitors (SGLT2s), is considerably higher than that of antiobesity pharmacotherapies, according to research published online Aug. 29 in Obesity.

Abstract
Full Text
Editorial

Warfarin Persistence Higher Than Previously Reported in A-Fib

TUESDAY, Sept. 6, 2016 (HealthDay News) -- Among patients with atrial fibrillation (AF), the proportion of warfarin persistence is 0.91 at one year and 0.73 at four years, according to a study published online Aug. 27 in Cardiovascular Therapeutics.

Abstract
Full Text (subscription or payment may be required)

Older Adults Employ High-Risk Methods to Obtain Opioids

TUESDAY, Sept. 6, 2016 (HealthDay News) -- About 15 percent of older adults use high-risk methods for obtaining prescription opioids, according to a study published online Aug. 26 in the Journal of the American Geriatrics Society.

Abstract
Full Text (subscription or payment may be required)

Rapid Improvement in Insulin Sensitivity With Bariatric Surgery

FRIDAY, Sept. 2, 2016 (HealthDay News) -- For obese patients without diabetes, bariatric surgery improves insulin sensitivity (IS), with more pronounced improvements for Roux-en-Y gastric bypass (RYGB) than for laparoscopic adjustable gastric banding (LAGB), according to a study published online Aug. 29 in Diabetes Care.

Full Text (subscription or payment may be required)

Avoiding Dry-Cooked Foods May Help Protect Against T2DM

FRIDAY, Sept. 2, 2016 (HealthDay News) -- Dry-heat cooking that produces advanced glycation end products (AGEs) may increase the risk of type 2 diabetes, according to a study published online July 29 in Diabetologia.

Full Text

Smokers More Prone to Relapse After Crohn's Surgery

FRIDAY, Sept. 2, 2016 (HealthDay News) -- Smoking increases the risk that Crohn's disease patients will experience clinical recurrence after bowel surgery, according to research published online Aug. 30 in The Lancet Gastroenterology and Hepatology.

Full Text

Infective Endocarditis From Injection Drug Use Increasing

FRIDAY, Sept. 2, 2016 (HealthDay News) -- The number of Americans hospitalized with infective endocarditis (IE) related to injecting opioids and heroin is on the rise, according to a study published in the Summer issue of Open Forum Infectious Diseases.

Abstract
Full Text

Rise in Endogenous Klebsiella pneumoniae Endophthalmitis

FRIDAY, Sept. 2, 2016 (HealthDay News) -- Increasing trends of endogenous Klebsiella pneumoniae endophthalmitis (EKPE) have been reported in Australia, according to research published online Aug. 26 in Clinical & Experimental Ophthalmology.

Abstract
Full Text (subscription or payment may be required)

Non-Drug Methods Effective for Treating Some Pain Conditions

FRIDAY, Sept. 2, 2016 (HealthDay News) -- Non-drug methods of managing pain from conditions such as headaches and arthritis appear to be effective, according to a review published in the September issue of the Mayo Clinic Proceedings.

Full Text

Risk of Injuries Up Around Period of Cancer Diagnosis

FRIDAY, Sept. 2, 2016 (HealthDay News) -- Patients with cancer have increased risks of iatrogenic and non-iatrogenic injuries shortly before and after cancer diagnosis, according to a study published online Aug. 31 in The BMJ.

Full Text
Editorial

Tailored Lay Health Educator Program Ups CRC Screening

FRIDAY, Sept. 2, 2016 (HealthDay News) -- An intervention involving bilingual/bicultural lay health educator (LHE) education can increase colorectal cancer (CRC) screening among Hmong-Americans, according to a study published online Aug. 26 in Cancer.

Abstract
Full Text (subscription or payment may be required)

Metformin, Sitagliptin Prolong Normoglycemia Remission in DKA

FRIDAY, Sept. 2, 2016 (HealthDay News) -- For patients with new-onset diabetic ketoacidosis (DKA) and severe hyperglycemia, metformin and sitagliptin treatment after normoglycemia remission correlate with increased relapse-free survival and prolonged remission, according to a study published online Aug. 29 in Diabetes Care.

Full Text (subscription or payment may be required)

Number of U.S. Adults Using Marijuana Up Significantly

THURSDAY, Sept. 1, 2016 (HealthDay News) -- As perceptions of marijuana change, more American adults are using marijuana than ever before, and they're using it more often, according to a study published online Aug. 31 in The Lancet Psychiatry.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Phone Apps Help Patients Reach Health, Fitness Goals

THURSDAY, Sept. 1, 2016 (HealthDay News) -- Various smartphone apps can help patients adopt a healthy lifestyle that might reduce risk of cardiovascular events, according to a review published online Aug. 31 in the Journal of the American Heart Association.

Abstract
Full Text

Long-Term Follow-Up Shows Bariatric Patients Keep Weight Off

THURSDAY, Sept. 1, 2016 (HealthDay News) -- Much of the weight lost via bariatric surgery appears to stay off for at least 10 years, according to a study published online Aug. 31 in JAMA Surgery.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Healthy Gut Microbiome Compromised in ICU Patients

THURSDAY, Sept. 1, 2016 (HealthDay News) -- Dysbiosis from unexpected environmental sources is seen within days after intensive care unit (ICU) admission, according to a study published online Aug. 31 in mSphere.

Full Text

Δ9-Tetrahydrocannabivarin Beneficial in Type 2 Diabetes

THURSDAY, Sept. 1, 2016 (HealthDay News) -- For patients with non-insulin-treated type 2 diabetes, Δ9-tetrahydrocannabivarin (THCV) reduces fasting plasma glucose, and improves pancreatic β-cell function, adiponectin, and apolipoprotein A, according to a study published online Aug. 29 in Diabetes Care.

Full Text (subscription or payment may be required)

Comorbidity Factors Identified for Exacerbation-Prone Asthma

THURSDAY, Sept. 1, 2016 (HealthDay News) -- Factors that are associated with exacerbation-prone asthma (EPA) have been identified, with blood eosinophils, body mass index, and bronchodilator responsiveness associated with exacerbation frequency, according to a study published online Aug. 24 in the American Journal of Respiratory and Critical Care Medicine.

Full Text (subscription or payment may be required)

Physician's Briefing
undefined
undefinedundefined