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THURSDAY, March 28, 2019 (Pharmacist's Briefing) -- Lifetime risks of hypertension under the American Heart Association (AHA) and American College of Cardiology (ACC) 2017 threshold exceed 75 percent for white men and African-American men and women, according to a study published online March 27 in JAMA Cardiology.
Vincent Chen, from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues quantified and compared lifetime risks for hypertension in white and African-American men and women under the hypertension thresholds of the AHA/ACC 2017 (single blood pressure measurement of ≥130/80 mm Hg or self-reported antihypertensive medication use) and the Seventh Joint National Commission (JNC7; ≥140/90 mm Hg or use of antihypertensive medications). Data were included for 13,160 participants who contributed 227,600 person-years of follow-up.
The researchers found that for participants entering the data set between age 20 and 30 years, the baseline prevalence of hypertension under the AHA/ACC 2017 threshold was 30.7 percent in white men, 23.1 percent in African-American men, 10.2 percent in white women, and 12.3 percent in African-American women. The lifetime risks for hypertension were 83.8, 86.1, 69.3, and 85.7 percent for white men, African-American men, white women, and African-American women, respectively. These risks were greater than the corresponding lifetime risks with the JNC7 thresholds (60.5, 74.7, 53.9, and 77.3 percent, respectively).
"Blood pressure awareness and primordial prevention early in the life course is needed to curb the epidemic of hypertension-associated diseases," the authors write.
One author disclosed serving as a consultant for NGM Bio.
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