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Metabolic Syndrome Linked to Increased Risk for Stroke Recurrence

Low levels of HDL cholesterol and having two or more components of metabolic syndrome predict recurrence

Cholesterol Dangers

THURSDAY, July 29, 2021 (HealthDay News) -- Metabolic syndrome and some of its components are associated with stroke recurrence, according to a review published online July 28 in Neurology.

Fangfang Zhang, M.D., from Xianxiang Central Hospital in China, and colleagues examined whether metabolic syndrome is associated with recurrence and mortality of stroke in a review of 13 cohort studies including 59,919 participants aged older than 60 years.

The researchers found that metabolic syndrome was associated with stroke recurrence overall (relative risk, 1.46). Low levels of high-density lipoprotein cholesterol and number of metabolic syndrome components (at least two) significantly predicted stroke recurrence (relative risks, 1.32 and 1.68, respectively), while elevated triglycerides, elevated waist circumference, hyperglycemia, and hypertension were not risk factors for stroke recurrence. There was a significant association observed for metabolic syndrome, but not its components, with all-cause mortality (relative risk, 1.27).

"These results add to the evidence that people with metabolic syndrome should take steps to modify their risk of second stroke and even death where possible, through medication, diet, exercise, and other recommended lifestyle changes such as stopping smoking," a coauthor said in a statement.

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