Mortality Risk Impacts Colon CA Screening in Dialysis Patients

Higher rate of screening among patients most likely to receive a transplant


FRIDAY, March 24, 2017 (HealthDay News) -- For patients on dialysis, colon cancer screening is more likely among those with the lowest risk of mortality, according to a study published online March 23 in the Journal of the American Society of Nephrology.

Christopher A. Carlos, M.D., from the University of California in San Francisco, and colleagues examined the frequency of colon cancer screening among patients on dialysis in a cohort study of 469,574 Medicare beneficiaries aged ≥50 years who received dialysis.

The researchers found that 11.6 percent of patients received a colon cancer screening test over a median follow-up of 1.5 years (57.9 tests per 1,000 person-years). The incidence rates were 27.9, 0.6, and 29.5 per 1,000 person-years for colonoscopy, flexible sigmoidoscopy, and fecal occult blood test, respectively. Compared with patients in the highest quartile of mortality risk, those in the lowest quartile were more likely to be screened (hazard ratio, 1.53; 65.1 versus 46.4 tests per 1,000 person years), representing a 33 percent increased rate of testing. Patients most likely to receive a transplant were also more likely to be screened than those least likely to receive a transplant (hazard ratio, 1.68).

"Colon cancer screening is being targeted toward dialysis patients at lowest risk of mortality and highest likelihood of transplantation, but absolute rates are high, suggesting overscreening," the authors write.

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