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December 2008 Briefing - Nephrology

Here are what the editors at HealthDay consider to be the most important developments in Nephrology for December 2008. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Kidney Disease Predicts Cardiovascular Mortality

MONDAY, Dec. 29 (HealthDay News) -- Chronic kidney disease may be as important a risk factor for cardiovascular mortality as is diabetes mellitus or prior myocardial infarction in elderly patients, according to research published Dec. 15 in the American Journal of Cardiology.

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Low Doses of Melamine Do Not Cause Kidney Damage

FRIDAY, Dec. 19 (HealthDay News) -- Low-dose exposure to melamine does not result in severe renal damage in children, according to a Fast Track article published online Dec. 18 in BMJ.

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Effect of Dialysis Method on Survival Variable

THURSDAY, Dec. 18 (HealthDay News) -- The potential survival benefit of peritoneal dialysis over hemodialysis depends on time since starting dialysis, age and presence of comorbidities, according to a report published online Dec. 17 in the Journal of the American Society of Nephrology.

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Diabetes Drug Well-Tolerated in Kidney Disease

THURSDAY, Dec. 11 (HealthDay News) -- A Phase I trial of the diabetes drug rosiglitazone indicates that the drug is safe and well-tolerated in patients with resistant primary focal segmental glomerulosclerosis (FSGS), although its pharmacokinetics differ from healthy individuals, according to a study published online Dec. 10 in the Clinical Journal of the American Society of Nephrology.

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Virus-Associated Kidney Transplant Failure Avoidable

THURSDAY, Dec. 4 (HealthDay News) -- Graft failure can be reduced in kidney transplant patients who develop BK virus-associated nephropathy (BKVAN) -- a normally dormant virus in healthy individuals -- by withdrawing one immunosuppressive drug soon after diagnosis, researchers report in the November issue of the Clinical Journal of the American Society of Nephrology.

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Contaminated Heparin Caused National Outbreak

WEDNESDAY, Dec. 3 (HealthDay News) -- Heparin contaminated with oversulfated chondroitin sulfate was responsible for the nationwide outbreak of allergic-type reactions and deaths that occurred at dialysis facilities in late 2007 and early 2008, according to study findings released online Dec. 3 in advance of publication in the Dec. 18 issue of the New England Journal of Medicine.

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