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June 2010 Briefing - Nephrology

Here are what the editors at HealthDay consider to be the most important developments in Nephrology for June 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Doctors Agree Malpractice Fears Drive Overuse of Tests

MONDAY, June 28 (HealthDay News) -- A large majority of physicians agree that the practice of defensive medicine -- stemming from malpractice concerns -- is responsible for an overuse of medical tests and procedures, according to a research letter in the June 28 issue of the Archives of Internal Medicine.

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Polycystic Kidney Growth Not Stopped by Sirolimus

MONDAY, June 28 (HealthDay News) -- Sirolimus does not stop polycystic kidney growth in individuals with autosomal dominant polycystic kidney disease (ADPKD) and early chronic kidney disease; everolimus, however, slows the increase in total kidney volume but does not slow the decline in progressive renal impairment in those with ADPKD, according to two studies published online June 26 in the New England Journal of Medicine to coincide with press conferences at the European Renal Association—European Dialysis and Transplant Association Congress, held from June 25 to 28 in Munich, Germany.

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In Stage V Kidney Disease, Early Dialysis Start Unneeded

MONDAY, June 28 (HealthDay News) -- In patients with stage V chronic kidney disease, early initiation of dialysis does not result in improved survival rates or clinical outcomes, according to a study published online June 27 in the New England Journal of Medicine to coincide with press conferences at the European Renal Association—European Dialysis and Transplant Association Congress, held from June 25 to 28 in Munich, Germany.

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Digoxin May Increase Mortality Risk in Hemodialysis Patients

FRIDAY, June 25 (HealthDay News) -- Digoxin use by patients on hemodialysis is linked to increased mortality, particularly in patients who have low pre-dialysis potassium concentrations, according to research published online June 24 in the Journal of the American Society of Nephrology.

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Severe Colitis Reported in Child After Rituximab Treatment

MONDAY, June 21 (HealthDay News) -- Children treated with rituximab for nephrotic syndrome (NS) may be at risk for severe T-cell mediated ulcerative colitis, as demonstrated by a case study published online June 21 in Pediatrics.

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Receipt of Kidney Care Less Likely in Black Communities

FRIDAY, June 18 (HealthDay News) -- Even when their kidney function is clearly declining, people living in communities with a high percentage of black residents are less likely to receive kidney care before they start dialysis than those living elsewhere, regardless of race, according to research published online June 17 in the Journal of the American Society of Nephrology.

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Increasing BMI Linked to Several Nephrolithiasis Risk Factors

FRIDAY, June 11 (HealthDay News) -- Increasing body mass index (BMI) is associated with the presence of several urinary stone risk factors in the urine chemistry, suggesting that weight loss should be part of a urinary stone prevention regimen, according to a study in the June issue of Urology.

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Fatal Medication Errors Rise in July at Teaching Hospitals

TUESDAY, June 8 (HealthDay News) -- In July there is a significant increase in fatal medication errors at medical institutions, and this spike is at least partly due to the arrival of new medical residents, according to a study published online May 29 in the Journal of General Internal Medicine.

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