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May 2010 Briefing - Nephrology

Here are what the editors at HealthDay consider to be the most important developments in Nephrology for May 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Cardiac Event Biomarker Linked to Volume Overload

FRIDAY, May 28 (HealthDay News) -- Among stable hemodialysis patients, N-terminal probrain type natriuretic peptide (NTproBNP) may not be associated with cardiac dysfunction but appears to be dependent on factors associated with volume overload, and may also be elevated in those with malnutrition, according to a study published online May 27 in the Clinical Journal of the American Society of Nephrology.

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Kidney Weight May Predict Transplant Complication Risk

FRIDAY, May 21 (HealthDay News) -- In kidney transplantation, receipt of an organ that is low in weight in relation to the body weight of the recipient raises the recipient's risk of complications and transplant failure, according to a study published May 20 in Journal of the American Society of Nephrology.

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Kidney Function Measures Predict Risk of Death

TUESDAY, May 18 (HealthDay News) -- In the general population, a low estimated glomerular filtration rate (eGFR) and a high urine albumin-to-creatinine ratio (ACR) are independent predictors of mortality, according to an analysis published online May 18 in The Lancet.

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Many General Internists Leave Field by Mid-Career

FRIDAY, May 14 (HealthDay News) -- Roughly one out of six general internists are leaving internal medicine by mid-career, a substantially higher proportion compared to internal medicine subspecialists, according to survey results published April 29 in the Journal of General Internal Medicine.

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New FDA Program Targets Misleading Drug Advertising

WEDNESDAY, May 12 (HealthDay News) -- The U.S. Food and Drug Administration has announced the launch of a new program to educate health care providers regarding their role in making certain that advertisements and promotions for prescription drugs are truthful and not misleading.

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Radiation for Wilms Tumor May Affect Future Pregnancies

TUESDAY, May 11 (HealthDay News) -- Women who have had prior radiation treatment for unilateral Wilms tumor diagnosed in childhood have a higher risk of pregnancy and birth complications, according to research published online May 10 in the Journal of Clinical Oncology.

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Kidney Removal in Elderly Does Not Improve Survival

MONDAY, May 10 (HealthDay News) -- Surgical management of localized renal tumors in elderly patients is not associated with increased survival compared with active surveillance, according to a study published online May 10 in Cancer.

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Microalbuminuria Can Predict Complications in Hypertension

FRIDAY, May 7 (HealthDay News) -- Microalbuminuria independently predicts higher risk of renal and cardiovascular complications in patients with primary hypertension but without diabetes, according to research published online April 29 in the Clinical Journal of the American Society of Nephrology.

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Study Questions Milk Drinking, Renal Cell Carcinoma Link

THURSDAY, May 6 (HealthDay News) -- Contrary to the findings of previous research, the suggested link between milk drinking and an increased risk for renal cell carcinoma (RCC) may be unwarranted, according to research published in the May issue of Cancer Epidemiology, Biomarkers & Prevention.

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Kidney Disease Therapy May Increase Cardiovascular Risks

TUESDAY, May 4 (HealthDay News) -- For patients with chronic kidney disease (CKD), therapy with erythropoiesis-stimulating agents (ESA) that target higher levels of hemoglobin increases the risk of stroke, hypertension and thrombosis, according to a meta-analysis published online May 3 in the Annals of Internal Medicine.

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