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Non-Infectious Problems Lower Dialysis Catheter Survival

Other risk factors have no significant impact on failure of peritoneal dialysis catheter

THURSDAY, March 10 (HealthDay News) -- The failure of peritoneal dialysis (PD) catheters is associated with catheter-related non-infectious problems, and other risk factors need not hinder the selection of patients for PD catheter initiation, according to a study published in the October-December 2010 issue of The Journal of Vascular Access.

Namita Singh, of the University of Texas Southwestern Medical Center in Dallas, and colleagues investigated the outcomes of PD catheters and evaluated factors affecting their survival. They reviewed the charts of 315 patients from one dialysis clinic whose first PD catheter was placed between January 2001 and September 2009. They collected relevant demographic and clinical information and identified factors independently linked with catheter survival. The primary end point was PD catheter failure, necessitating removal of a dysfunctional catheter due to catheter-related problems.

The researchers found that, overall, PD catheters had excellent one-, two-, and three-year survival rates (92.9, 91.9, and 91.1 percent, respectively). The only factor that significantly reduced catheter survival time was PD catheter-related non-infectious problems (hazard ratio, 22.467). In patients with any catheter-related non-infectious complication, catheter failure was most likely to occur in the first three months following surgery. There was no significant association between PD catheter survival and other variables, including age, body mass index, diabetic status, comorbidities, previous abdominal surgeries, or infections.

"Based on our study results, we propose that age, obesity, previous abdominal surgeries, and comorbidities should not be considered as barriers in selecting patients for PD," the authors write.

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