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September 2011 Briefing - Nephrology

Here are what the editors at HealthDay consider to be the most important developments in Nephrology for September 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Doctors, Patients Identify Tacit Clues in Their Interactions

FRIDAY, Sept. 30 (HealthDay News) -- Both doctors and patients identify tacit clues as well as judgments based on these clues during video elicitation interviews of health maintenance examinations, according to a study published in the October issue of the Journal of Evaluation in Clinical Practice.

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Calcineurin-Inhibitor-Sparing Regimens Improve Outcomes

WEDNESDAY, Sept. 28 (HealthDay News) -- Use of calciuneurin-inhibitor-sparing regimens immediately after kidney transplantation is associated with improved outcomes, including less delayed graft function, improved graft function, and less new-onset diabetes, according to a meta-analysis published online Sept. 23 in the Journal of the American Society of Nephrology.

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U.S. Docs Feel They Give More Patient Care Than Required

TUESDAY, Sept. 27 (HealthDay News) -- Many primary care physicians in the United States believe that their patients are receiving too much medical care, and that the pressure to do more than is necessary could be reduced by malpractice reform, adjusting financial incentives, and spending more time with patients, according to a study published in the Sept. 26 issue of the Archives of Internal Medicine.

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Reasons for Referral to Specific Docs Differ Among Physicians

TUESDAY, Sept. 27 (HealthDay News) -- Primary care physicians (PCPs) and medical and surgical specialists differ in their reasons for selecting specific colleagues for referrals, with PCPs more concerned about physician communication and medical record sharing than specialists, according to a study published online Sept. 16 in the Journal of General Internal Medicine.

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Soliris Approval Expanded to Include Rare Blood Disorder

FRIDAY, Sept. 23 (HealthDay News) -- Soliris (eculizumab) has been approved by the U.S. Food and Drug Administration as the first drug to treat atypical hemolytic uremic syndrome (aHUS), a rare blood disease that may trigger kidney failure, stroke or death.

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Serum Amino Acids Are Potential Biomarkers for Renal Cell Cancer

FRIDAY, Sept. 23 (HealthDay News) -- The levels of certain serum amino acids are significantly different in patients with renal cell carcinoma and show potential as biomarkers with predictive value for tumor recurrence and overall survival, according to a study published in the October issue of The Journal of Urology.

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SNP in SUV39H2 Tied to Complications in Diabetes

THURSDAY, Sept. 22 (HealthDay News) -- The minor T-allele of exonic single nucleotide polymorphism (SNP) rs17353856 in SUV39H2 is associated with retinopathy in patients with type 1 diabetes, and shows a trend toward an association with diabetic nephropathy and cardiovascular disease, according to a study published online Sept. 6 in Diabetes.

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Risk Up for Patients During Long Interdialytic Interval

WEDNESDAY, Sept. 21 (HealthDay News) -- For patients receiving hemodialysis, mortality and adverse cardiovascular-related events occur mainly on the day after the long interdialytic interval, rather than on other days, according to a study published in the Sept. 22 issue of the New England Journal of Medicine.

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Mortality Up in Hospitals With More Minority Trauma Patients

WEDNESDAY, Sept. 21 (HealthDay News) -- The odds of in-hospital mortality for trauma patients are associated with the proportion of minority patients in the hospital, according to a study published online Sept. 19 in the Archives of Surgery.

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Work Intensity Similar Across Physician Specialties

MONDAY, Sept. 19 (HealthDay News) -- The level of physician work intensity appears to be similar among specialties, with variations in the specific dimensions of stress, physical demands, performance, and temporal demand, according to a study published online Sept. 3 in Medical Care.

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Cold Ischemia Time Tied to Delayed Kidney Graft Function

MONDAY, Sept. 19 (HealthDay News) -- Increasing cold ischemia time (CIT) in expanded-criteria donor (ECD) kidney pairs is a risk factor for delayed graft function (DGF), but has no effect on graft survival, according to a study published online Sept. 11 in the American Journal of Transplantation.

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Long-Term Nonaspirin NSAID Use Ups Renal Cell Cancer Risk

WEDNESDAY, Sept. 14 (HealthDay News) -- Use of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs), but not aspirin and acetaminophen, is associated with an increased risk of renal cell cancer (RCC), with increased duration of use correlated with an elevated risk, according to a study published in the Sept. 12 issue of the Archives of Internal Medicine.

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Many Mistakenly Believe FDA OKs Only Safe, Effective Drugs

WEDNESDAY, Sept. 14 (HealthDay News) -- A considerable proportion of the U.S. public mistakenly believes that the U.S. Food and Drug Administration approves only effective and safe drugs, but providing consumer explanations can lead to better drug choices, according to a study published in the Sept. 12 issue of the Archives of Internal Medicine.

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Prehypertension-Hypertension Conversion Rate Tied to Race

WEDNESDAY, Sept. 14 (HealthDay News) -- Conversion from prehypertension to hypertension is more accelerated in blacks than in whites, according to a study published online Sept. 12 in Hypertension.

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Comparative Efficacy Proposed for European Drug Approval

WEDNESDAY, Sept. 7 (HealthDay News) -- New drugs should be compared with existing treatments instead of placebo before their approval in Europe, according to a report published online Sept. 6 in the BMJ.

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Odds of Board Certification Vary in New Doctors

WEDNESDAY, Sept. 7 (HealthDay News) -- Certification of recent U.S. medical school graduates by the American Board of Medical Specialties (ABMS) varies across specialties by educational and demographic factors, according to a study published in the Sept. 7 medical education-themed issue of the Journal of the American Medical Association.

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Medical Students Show Racial, Cultural Patient Preference

WEDNESDAY, Sept. 7 (HealthDay News) -- Medical students may have a preferential bias toward whites and wealthier patients, but this does not appear to influence their clinical decision making or physician-patient interactions, according to a study published in the Sept. 7 medical education-themed issue of the Journal of the American Medical Association.

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Many Hospital Staff Uniforms Contaminated With Bacteria

WEDNESDAY, Sept. 7 (HealthDay News) -- More than 60 percent of hospital staff uniforms are contaminated with potentially pathogenic bacteria, including drug-resistant species, according to a study published in the September issue of the American Journal of Infection Control.

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Immunoadsorption Therapy Effective in E. coli-Induced HUS

TUESDAY, Sept. 6 (HealthDay News) -- Immunoadsorption of immunoglobulin G (IgG) antibodies can safely be used to treat neurological complications in patients with Escherichia coli (E. coli) O104:H4-induced hemolytic uremic syndrome (HUS), according to a study published online Sept. 5 in The Lancet.

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FDA: New Contraindication, Updated Warning for Reclast

FRIDAY, Sept. 2 (HealthDay News) -- The drug label for Reclast (zoledronic acid) has been updated to reflect the risk of kidney failure, according to a safety alert issued Sept. 1 by the U.S. Food and Drug Administration.

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