THURSDAY, Jan. 8 (HealthDay News) -- Women's access to renal transplantation is affected by their age and comorbidities, according to a study published online Jan. 7 in the Journal of the American Society of Nephrology.
Dorry L. Segev, M.D., of Johns Hopkins University in Baltimore, and colleagues analyzed data from 563,197 patients with first-onset end-stage renal disease and compared the relative risks of mortality between men and women as well as across different age ranges and in the absence or presence of common comorbidities.
Women had 11 percent less access to transplantation than men, the investigators found. Access was the same between the genders in those aged 18 to 45 years, but despite the fact that transplantation gave men and women similar survival benefits across all ages, as age increased, women's access to transplantation declined dramatically, and women with comorbidities also had less access to transplantation compared to men with a similar health profile, the researchers report.
"We have identified important effect modifiers not previously accounted for in national population-based reports of a gender disparity in access to transplantation," the authors write. "More work is needed to understand better why this disparity is occurring to inform clinical decision-making and interventions to increase access to transplantation for women who stand to benefit from it."
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