See What HealthDay Can Do For You
Contact Us

Exercise May Slow Brain Deterioration in Alzheimer Disease

Findings did not differ between aerobic exercise and stretching and toning

women in pool

MONDAY, Sept. 23, 2019 (HealthDay News) -- Exercising may delay brain deterioration in people at high risk for Alzheimer disease, according to a proof-of-concept study published Sept. 17 in the Journal of Alzheimer's Disease.

Takashi Tarumi, Ph.D., from Texas Health Presbyterian Hospital in Dallas, and colleagues randomly assigned 70 patients with amnestic mild cognitive impairment (aMCI) to 12 months of aerobic exercise training (AET) or stretching and toning (SAT; active control) interventions. The California Verbal Learning Test-Second Edition and the Delis-Kaplan Executive Function System were used to assess neuropsychological outcomes.

The researchers found that memory and executive function performance improved over time but did not differ between the groups. There were no differences between the groups with respect to brain volume decreases and precuneus amyloid-β plaque deposition increases over time. The AET group had significant improvements in cardiorespiratory fitness compared with the SAT group. AET was associated with reduced hippocampal atrophy in amyloid-positive patients compared with the SAT group.

"The AET and SAT groups both showed evidence of slightly improved neuropsychological scores in previously sedentary aMCI patients," the authors write.

Abstract/Full Text (subscription or payment may be required)

Physician's Briefing

HealthDay

HealthDay is the world’s largest syndicator of health news and content, and providers of custom health/medical content.

Consumer Health News

A health news feed, reviewing the latest and most topical health stories.

Professional News

A news feed for Health Care Professionals (HCPs), reviewing latest medical research and approvals.