AANS: Alcohol, Aspirin Does Not Predict Brain Hemorrhage

Age is most important predictor of delayed hemorrhage in patients with brain injury

MONDAY, April 16 (HealthDay News) -- Neither alcohol nor anti-platelet use is associated with worsening intracranial hemorrhage in patients with traumatic brain injury, according to research presented this week at the annual meeting of the American Association of Neurological Surgeons in Washington, D.C.

Arien J. Smith, M.D., of the Mount Sinai School of Medicine in New York City, and colleagues studied 150 patients who were hospitalized with traumatic brain injury due to the following causes: falls (50 percent), assaults (27 percent), motor vehicle accidents (11 percent) and pedestrian injury (14 percent). They found that 53.8 percent of the subjects had blood-alcohol levels above 100 mg/dl and that a small number of subjects were taking aspirin (8.8 percent), Plavix (4.4 percent) and coumadin (2.2 percent). All of the patients underwent a baseline CT scan and a second scan within 6-24 hours of hospitalization.

The researchers found that neither ethanol nor anti-platelet use were significantly associated with delayed hemorrhage or clinical outcome. Instead, age seemed to be to the most important factor. They found that patients with delayed worsening of hemorrhage were likely to be older than those without (58 years versus 45.7 years).

"Through a second year of data accrual, continued investigation is ongoing, especially to observe for any differences in patients taking anti-platelet agents, although in the study population, these patients constitute a minority, while ethanol intoxication is more prevalent," the authors concluded.


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