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Adverse Events After Carotid Surgery Similar to Trials

Short-term rates seen in randomized trials can be achieved in routine practice

FRIDAY, Oct. 12 (HealthDay News) -- The short-term stroke and death rates observed after carotid endarterectomy in randomized clinical trials can also be achieved in routine clinical practice, according to a report in the October issue of the Archives of Neurology.

Thomas E. Feasby, M.D., from the University of Calgary in Alberta, Canada, and colleagues reviewed the medical records on short-term adverse events after carotid endarterectomy in 3,283 patients in routine clinical practice in western Canada and compared this with data from randomized clinical trials.

The researchers found that the extrapolated 30-day post-surgery rate of in-hospital ischemic stroke or death was 4.9 percent in symptomatic patients and 4.1 percent for asymptomatic patients, which was comparable to or better than the results from clinical trials for symptomatic patients but slightly worse for asymptomatic patients. However, they note that about 45 percent of hospitals had higher rates of adverse events than the recommended guidelines.

"This large population-based study shows that the randomized clinical trial results for carotid endarterectomy can be achieved in the real world," Feasby and colleagues conclude.

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