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April 2012 Briefing - Nursing

Here are what the editors at HealthDay consider to be the most important developments in Nursing for April 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Prenatal Insecticide Exposure Alters Developing Brain

MONDAY, April 30 (HealthDay News) -- Prenatal exposure to chlorpyrifos (CPF), an organophosphate insecticide, correlates with structural changes in the developing brain, according to a study published online April 30 in the Proceedings of the National Academy of Sciences.

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Screening Benefits Women in 40s With High Breast CA Risk

MONDAY, April 30 (HealthDay News) -- Women in their 40s, with at least a two-fold increased risk of breast cancer, benefit from biennial screening mammography; and having extremely dense breasts or first-degree relatives with breast cancer is associated with a two-fold increased risk of breast cancer for women in their 40s, according to two studies published in the May 1 issue of the Annals of Internal Medicine.

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Genetic Link Identified for Multiple Forms of Glaucoma

MONDAY, April 30 (HealthDay News) -- Two genomic regions have been identified that are associated with normal-pressure glaucoma (NPG) and optic nerve disease in exfoliation-syndrome glaucoma (ESG), possibly through the transforming growth factor beta (TGF-beta) signaling pathway, according to a study published online April 26 in PLoS Genetics.

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Levaquin Approved to Treat or Prevent Plague

MONDAY, April 30 (HealthDay News) -- Approval of the antibiotic Levaquin (levofloxacin) has been expanded by the U.S. Food and Drug Administration to include plague, a rare but deadly bacterial infection.

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Electronic Reminders Up Meds Adherence in Short Term

MONDAY, April 30 (HealthDay News) -- The use of electronic reminders (short message service [SMS] reminders, electronic reminder devices, or pagers) is associated with improved adherence to chronic medications in the short term, according to a review published online April 25 in the Journal of the American Medical Informatics Association.

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Imaging Provides Clues to Distribution of Fat in Children

MONDAY, April 30 (HealthDay News) -- The use of imaging studies has contributed to an understanding of differences in fat distribution and their link to metabolic disease in childhood, according to research published online April 22 in Obesity Reviews.

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Sleep Measures Do Not Predict Clinical Pain in Fibromyalgia

FRIDAY, April 27 (HealthDay News) -- For patients with fibromyalgia, spatial extent of pain, pain aftersensation, and negative mood account for approximately one-third of the variance in clinical pain, but sleep measures do not significantly predict pain, according to a study published in the April issue of The Journal of Pain.

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Early Axonal Dysfunction Precedes Diabetic Neuropathy

FRIDAY, April 27 (HealthDay News) -- Early axonal dysfunction may be detected prior to the development of clinical symptoms of diabetic neuropathy, according to a study published online April 20 in Diabetes.

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Stress Reduction Ups Health Status in Type 2 Diabetes

FRIDAY, April 27 (HealthDay News) -- A mindfulness-based stress reduction (MBSR) intervention is effective at improving health status and lowering levels of depression among patients with type 2 diabetes, according to a study published in the May issue of Diabetes Care.

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Persistent Constipation Rates May Be Lower Than Reported

FRIDAY, April 27 (HealthDay News) -- The clinical symptoms of persistent and nonpersistent chronic constipation (CC) are similar, with persistent CC estimated to have a prevalence of 3 percent, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.

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About Half of Teens Who Self-Harm Were Frequently Bullied

FRIDAY, April 27 (HealthDay News) -- About half of young adolescents who have self-harmed were frequently bullied, and self-harm among the bullied is more likely in those with mental health problems, a family history of suicide, or a history of being physically abused by an adult, according to a study published online April 26 in BMJ.

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Childhood Socioeconomic Status Affects Brain Volume

FRIDAY, April 27 (HealthDay News) -- Childhood socioeconomic status affects hippocampal volume in older adults, after adjusting for adult socioeconomic status, gender, education, and other factors, according to a study published in the May issue of the Annals of Neurology.

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Cancer Worry Linked to Continued Symptom Burden

FRIDAY, April 27 (HealthDay News) -- Age, fatigue, symptom burden, and risk perception are significantly associated with greater cancer worry three years after completing adjuvant treatment for breast cancer, according to a study published online March 15 in Psycho-Oncology.

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Prevalence, Patterns of Modic Changes in Spine Described

FRIDAY, April 27 (HealthDay News) -- Modic changes (MCs) are frequently detected in the lumbar spine, and their presence is associated with age, according to a study published online April 20 in The Spine Journal.

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Excessive Neutropenia for Weekly Everolimus + Docetaxel

FRIDAY, April 27 (HealthDay News) -- For patients with metastatic breast cancer, weekly treatment with everolimus plus docetaxel every three weeks results in dose-limiting neutropenia and variable clearance of both drugs, according to a phase 1 study published in the May 1 issue of Cancer.

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Sunscreen Use May Lead to Vitamin D Deficiency

FRIDAY, April 27 (HealthDay News) -- Using the amount and sun protection factor (SPF) of sunscreen recommended by the World Health Organization (WHO) is associated with little or no vitamin D production, suggesting that regular sunscreen use may lead to vitamin D deficiency, according to research published online April 18 in the British Journal of Dermatology.

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Antiretroviral Prophylaxis May Cut Breastfeeding HIV Spread

THURSDAY, April 26 (HealthDay News) -- Breastfeeding HIV-infected mothers are less likely to transmit the virus to their infants when either receive antiretroviral drugs, although weaning at six months may be detrimental, according to updated trial results published online April 26 in The Lancet.

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Sleep of Short Duration Common in U.S. Workers

THURSDAY, April 26 (HealthDay News) -- A substantial proportion of workers in the United States get less sleep than recommended by the National Sleep Foundation, according to a report published in the April 27 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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Berries May Slow Cognitive Decline in Older Women

THURSDAY, April 26 (HealthDay News) -- Flavonoid-rich blueberries and strawberries may reduce cognitive decline in elderly women, according to a study published online April 25 in the Annals of Neurology.

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Heart Surgery Safe for Compensated Cirrhosis Patients

THURSDAY, April 26 (HealthDay News) -- Patients with compensated cirrhosis, defined by a Child-Pugh (CP) score of <8, have no significant increase in postoperative mortality and morbidity following cardiac surgery with cardiopulmonary bypass, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.

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Nutrition, Exercise Guidelines Updated for Cancer Survivors

THURSDAY, April 26 (HealthDay News) -- The American Cancer Society has updated the 2006 guidelines to provide new evidence and clinical practices related to nutrition and physical activity for cancer survivors during the continuum of cancer care, according to a report published online April 26 in CA: A Cancer Journal for Clinicians.

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Hyperalgesia Similar With Drug Therapies for Heroin Addiction

THURSDAY, April 26 (HealthDay News) -- Heroin-addicted patients treated with methadone or buprenorphine have a heightened sensitivity to pain, and the hyperalgesia does not change over the course of treatment, according to a study published in the April issue of The Journal of Pain.

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Age, Life Expectancy Influence Termination of PSA Screening

THURSDAY, April 26 (HealthDay News) -- Most primary care providers consider both a man's age and life expectancy in deciding whether to discontinue prostate-specific antigen (PSA) screenings, but multiple factors are involved in this decision, according to a study published online April 19 in Cancer.

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Subtype Best Predictor of Basal Cell Carcinoma Invasion Depth

THURSDAY, April 26 (HealthDay News) -- Basal cell carcinoma (BCC) subtype identified on biopsy and excision specimens is the best predictor of depth of invasion, according to a study published online April 16 in the Journal of the American Academy of Dermatology.

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Modulator of mGluR5 Improves Features of Autism in Mice

THURSDAY, April 26 (HealthDay News) -- A selective negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGluR5), GRN-529, improves some behavioral features of autism in mouse models of the disorder, according to an experimental study published in the April 25 issue of Science Translational Medicine.

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Thiazolidinediones Tied to Lower Cancer Risk in Diabetes Patients

THURSDAY, April 26 (HealthDay News) -- Thiazolidinediones are associated with a lower risk of liver and colorectal cancer in patients with type 2 diabetes, according to a study published in the May issue of Hepatology.

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Early Menopause Ups Risk of Osteoporosis, Fractures, Death

THURSDAY, April 26 (HealthDay News) -- The occurrence of menopause before age 47 correlates with increased osteoporosis at age 77, increased incidence of fragility fractures, and increased mortality, according to a study published online April 25 in BJOG: An International Journal of Obstetrics and Gynaecology.

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Accelerated Aging Evident in Cocaine-Dependent Individuals

THURSDAY, April 26 (HealthDay News) -- The brains of individuals addicted to cocaine show accelerated loss of gray matter over and above the loss due to normal aging, according to a letter published online April 24 in Molecular Psychiatry.

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Adjuvant Therapy Shows Promise in Biliary Tract Cancer

THURSDAY, April 26 (HealthDay News) -- For patients with biliary tract cancers, postresection adjuvant therapy with chemotherapy or chemoradiotherapy appears to be beneficial in treating patients with biliary tract cancers, with significant improvement seen for patients with node or margin positivity, according to research published online April 23 in the Journal of Clinical Oncology.

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Erosive, but Not Nonerosive, GERD Ups Esophageal CA Risk

WEDNESDAY, April 25 (HealthDay News) -- Patients with gastroesophageal reflux disease with a history of esophagitis are at increased risk for esophageal adenocarcinoma, although the absolute risk is low, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.

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Low-Dose CT Noninferior for Diagnosing Appendicitis

WEDNESDAY, April 25 (HealthDay News) -- For young adults with suspected appendicitis, low-dose computed tomography (CT) is noninferior to standard-dose CT with respect to negative appendectomy rates, according to a study published in the April 26 issue of the New England Journal of Medicine.

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Warfarin Keeps Stroke Risk Low in Patients With A-Fib

WEDNESDAY, April 25 (HealthDay News) -- Use of warfarin for stroke prevention in patients with nonvalvular atrial fibrillation (AF) is associated with a low risk of stroke or systemic embolism, according to a meta-analysis published in the April 23 issue of the Archives of Internal Medicine.

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Primary Enforcement Leads to Higher Teen Seat Belt Use

WEDNESDAY, April 25 (HealthDay News) -- Teen drivers and passengers in states with secondary safety belt enforcement laws are less likely to wear seat belts compared with teens in states with primary enforcement, according to a study published in the American Journal of Public Health.

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Inducing for Premature Rupture of Membranes Not Better

WEDNESDAY, April 25 (HealthDay News) -- In pregnant women with preterm prelabor rupture of membranes (PPROM), inducing labor and watchful waiting are similarly effective in terms of pregnancy outcomes such as neonatal sepsis and cesarean section, according to a study published online April 24 in PLoS Medicine.

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Amyloid-β-Linked Cognitive Decline Linked to Phospho-Tau

WEDNESDAY, April 25 (HealthDay News) -- In cognitively normal older individuals, amyloid-β (Aβ)-associated longitudinal cognitive decline only occurs in the presence of elevated phospho-tau 181 (p-tau181p) in the cerebrospinal fluid (CSF), according to a study published online April 23 in the Archives of Neurology.

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Ultrasound May Safely Rule Out DVT in Pregnancy

WEDNESDAY, April 25 (HealthDay News) -- For pregnant and postpartum women, a single complete compression ultrasonography may safely exclude a diagnosis of deep vein thrombosis, according to a study published online April 24 in BMJ.

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Bone Metabolism, Vitamin D Key in Postkyphoplasty Breaks

WEDNESDAY, April 25 (HealthDay News) -- For postmenopausal women with osteoporosis, bone metabolism and 25-hydroxyvitamin D (25[OH]D) levels are associated with postkyphoplasty recurrent vertebral compression fractures, according to a study published online April 12 in The Spine Journal.

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Botox Modestly Improves Chronic Headaches, Migraines

WEDNESDAY, April 25 (HealthDay News) -- Botulinum toxin A provides a modest benefit for patients with chronic migraine headaches and chronic daily headaches, compared with placebo, according to a meta-analysis published in the April 25 issue of the Journal of the American Medical Association.

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Nursing Excellence Ups Very Low Birth Weight Baby Outcomes

WEDNESDAY, April 25 (HealthDay News) -- For very low birth weight (VLBW) infants, hospitals with recognition for nursing excellence (RNE) have significantly lower rates for hospital infection, seven-day mortality, and severe intraventricular hemorrhage, but not 28-day mortality or hospital stay mortality, according to a study published in the April 25 issue of the Journal of the American Medical Association.

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Resistance Training Aids Memory in Senior Women

WEDNESDAY, April 25 (HealthDay News) -- For senior women with mild cognitive impairment, twice-weekly resistance training (RT) for six months is associated with improved cognition and brain plasticity compared with balance and tone (BAT) exercises, according to a research letter published in the April 23 issue of the Archives of Internal Medicine.

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High Survival With Surgery in Low-Risk Neuroblastoma

WEDNESDAY, April 25 (HealthDay News) -- Surgery alone results in high five-year event-free and overall survival (EFS and OS) rates for patients with low-risk stage 2a and 2b neuroblastoma (NBL), according to research published online April 23 in the Journal of Clinical Oncology.

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Anatomic Existence of the G-Spot Reported

WEDNESDAY, April 25 (HealthDay News) -- The anatomic existence of the G-spot has been documented, and it has been identified as a distinguishable anatomic structure located on the dorsal perineal membrane, according to a study published in the May issue of The Journal of Sexual Medicine.

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Exposure to Violence Wears on Children's DNA

WEDNESDAY, April 25 (HealthDay News) -- Children who are exposed to violence have significantly more telomere erosion than their unexposed peers, according to a study published online April 24 in Molecular Psychiatry.

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Mortality High for Cardiac Device Infective Endocarditis

TUESDAY, April 24 (HealthDay News) -- Patients with infective endocarditis involving implanted cardiac devices experience high in-hospital and one-year mortality rates, particularly if there is valve involvement, according to a study published in the April 25 issue of the Journal of the American Medical Association.

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Text Messages to Parents Promote Flu Shots for Children

TUESDAY, April 24 (HealthDay News) -- A text messaging-based intervention increases influenza vaccination compared with usual care in a low-income, urban population, although overall rates of vaccination remain low, according to a study published in the April 25 issue of the Journal of the American Medical Association.

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USPSTF Guidelines Haven't Changed PSA Screening Practice

TUESDAY, April 24 (HealthDay News) -- Despite the 2008 changes in U.S. Preventive Services Task Force (USPSTF) recommendations against prostate-specific antigen (PSA)-based screening for prostate cancer in men 75 years or older, screening rates remained unchanged for men of all ages between 2005 and 2010, according to a research letter published in the April 25 issue of the Journal of the American Medical Association.

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2001 to 2010 Saw 74 Percent Drop in Global Measles Mortality

TUESDAY, April 24 (HealthDay News) -- From 2001 to 2010, there was a 74 percent decrease in estimated global measles mortality, with mortality in India and the World Health Organization (WHO) African region accounting for most of the estimated cases in 2010, according to a study published online April 24 in The Lancet.

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Oxiplex Improves Outcomes After Lumbar Discectomy

TUESDAY, April 24 (HealthDay News) -- The use of Oxiplex gel (containing carboxymethylcellulose, polyethylene oxide, and calcium) to coat the surgical site during discectomy procedures for the treatment of lumbar disc herniation is associated with improved clinical outcomes, according to a study published in the April 15 issue of Spine.

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Patients With Acute Low Back Pain Have Poor Prognosis

TUESDAY, April 24 (HealthDay News) -- Few patients with acute low back pain (LBP), with or without sciatica, declare sick leave; however, approximately half have one or more recurrences and a considerable proportion experience chronic pain six months or longer after the initial episode, according to a study published in the April 15 issue of Spine.

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Lasting Benefit for Rotating-Platform Knee Arthroplasty

TUESDAY, April 24 (HealthDay News) -- After at least 10 years of follow-up, total knee replacement using a second-generation, cemented, rotating-platform, posterior-stabilized total knee prosthesis offers excellent and durable clinical and radiologic results in active patients, according to a study published in the April 4 issue of The Journal of Bone & Joint Surgery.

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Meds, Clinic Noncompliance Linked to Mortality in Diabetes

TUESDAY, April 24 (HealthDay News) -- Insulin-treated patients with type 2 diabetes who are noncompliant with their medication or clinic appointments face increased all-cause mortality, according to a study published online April 17 in Diabetes Care.

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S. Aureus, Enterotoxins ID'd in Atopic Keratoconjunctivitis

MONDAY, April 23 (HealthDay News) -- Staphylococcus aureus (S. aureus) and S. aureus-secreted enterotoxins (SE) are frequently found in patients with atopic keratoconjunctivitis (AKC), particularly in those with corneal ulceration, according to a study published online April 10 in Allergy.

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Bladder Cancer Diagnosis Encourages Smokers to Quit

MONDAY, April 23 (HealthDay News) -- Smokers with a new diagnosis of bladder cancer are significantly more likely to quit compared with smokers in the general population, according to a study published online April 23 in the Journal of Clinical Oncology.

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Gritti-Stokes Amputations Beneficial for Trauma Patients

MONDAY, April 23 (HealthDay News) -- The Gritti-Stokes amputation procedure is beneficial and appears to be safe for patients in a trauma setting, according to a study published in the April 4 issue of The Journal of Bone & Joint Surgery.

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Angiotensin Receptor Blockers Reduce No-Reflow Post-PCI

MONDAY, April 23 (HealthDay News) -- For patients with acute myocardial infarction (AMI), pretreatment with angiotensin receptor blockers (ARBs) is linked with reduced incidence of the no-reflow phenomenon after percutaneous coronary intervention (PCI), according to a study published online April 10 in Cardiovascular Therapeutics.

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Shingles Vaccine Generally Well Tolerated in Older Adults

MONDAY, April 23 (HealthDay News) -- The zoster vaccine is safe and well tolerated in older adults, despite an increased risk of allergic reaction in the days following vaccination, according to a study published in the Journal of Internal Medicine.

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Metabolites Linked to Insulin Resistance in Normoglycemia

MONDAY, April 23 (HealthDay News) -- Twenty metabolites, including amino acids, intermediates in glucose synthesis, ketone bodies, and fatty acids, are associated with insulin resistance, according to a study published online April 17 in Diabetes.

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Efficacy of Serotonin Receptor Inhibitors in Autism Unclear

MONDAY, April 23 (HealthDay News) -- Serotonin receptor inhibitors (SRIs) have a small but significant effect in treating repetitive behaviors in autism spectrum disorders (ASD), but this effect may be due to selective publication of trial results, according to a study published online April 23 in Pediatrics.

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High BMI Tied to Non-Specific Foot Pain, Plantar Heel Pain

MONDAY, April 23 (HealthDay News) -- Increased body mass index (BMI) correlates with non-specific foot pain in the general population, and with chronic plantar heel pain in a non-athletic population, according to a meta-analysis published online April 13 in Obesity Reviews.

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Reliability, Validity of Clinical Dehydration Scale Questioned

MONDAY, April 23 (HealthDay News) -- A previously derived clinical dehydration scale (CDS) is characterized by moderate interobserver reliability and weak links with objective measures of disease severity for children administered intravenous rehydration, according to a study published online April 23 in Pediatrics.

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Massachusetts Saw Recent Drop in Pediatric Obesity

MONDAY, April 23 (HealthDay News) -- The prevalence of obesity among children younger than 6 years in a Massachusetts cohort was stable from 1999 to 2003, and decreased from 2004 to 2008, according to a study published online April 23 in Pediatrics.

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Pediatric Regimen Beats Adult Chemo for Young Adults With ALL

MONDAY, April 23 (HealthDay News) -- Adolescent and young adult patients with acute lymphoblastic leukemia (ALL) who are treated with pediatric-inspired regimens exhibit lower all-cause mortality, higher complete remission and event-free survival rates, and lower relapse rates compared with those treated with conventional adult-chemotherapy regimens, according to a study published in the May issue of the American Journal of Hematology.

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Pain Coping Ability Impacts Lupus Symptomology

MONDAY, April 23 (HealthDay News) -- Pain coping strategies can significantly impact the physical symptoms and psychological distress experienced by patients with systemic lupus erythematosus (SLE), according to a study published online April 13 in Arthritis Care & Research.

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Insulin Resistance Cut-Off Established From Clamp Data

MONDAY, April 23 (HealthDay News) -- Cut-offs for predicting insulin resistance based on hyperinsulinemic-euglycemic clamp data and routinely measured clinical and biochemical variables have been determined, according to a study published online April 17 in Diabetes Care.

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Novel Balanced Chromosome Abnormalities Found in Autism

FRIDAY, April 20 (HealthDay News) -- New genetic variants associated with balanced alterations of chromosome structure have been identified in individuals with autism and related neurodevelopmental disorders, many of which are also present in individuals with schizophrenia, according to a study published online April 19 in Cell.

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Patient-Centered Approach Key for T2DM Management

FRIDAY, April 20 (HealthDay News) -- Treatment of type 2 diabetes should be personalized in a patient-centered approach, with diet, exercise, and education forming the basis of any treatment program, supplemented by medications as necessary, according to a joint position statement issued by the American Diabetes Association and the European Association for the Study of Diabetes, published online April 19 in Diabetes Care.

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Marijuana and Tobacco Co-Use Common in Young Adults

FRIDAY, April 20 (HealthDay News) -- Half of young adult tobacco smokers also have used marijuana in the last 30 days, and co-use occurs on nearly half of the days either substance is used, according to a study published online April 19 in Addiction Science & Clinical Practice.

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Uric Acid Levels Predict Death in Acute Coronary Syndrome

FRIDAY, April 20 (HealthDay News) -- Elevated uric acid levels are predictive of one-year mortality in patients with acute coronary syndrome, according to a study published in the May 1 issue of The American Journal of Cardiology.

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Computerized Therapy Equal to Usual Care for Depressed Teens

FRIDAY, April 20 (HealthDay News) -- For adolescents presenting with depressive symptoms, use of a computerized cognitive behavior therapy intervention (SPARX; Smart, Positive, Active, Realistic, X-factor thoughts) is a potential alternative to usual care, according to a study published online April 19 in BMJ.

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QRS Width on ECG Linked to Sudden Cardiac Arrest in CAD

FRIDAY, April 20 (HealthDay News) -- For patients with coronary artery disease (CAD), QRS width on electrocardiogram and echocardiographic evidence of heart failure are associated with out-of-hospital sudden cardiac arrest (SCA), regardless of whether they have a history of previous myocardial infarction (MI), according to a study published in the May 1 issue of The American Journal of Cardiology.

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New Fat Grafting Procedures Improve Breast Reconstruction

FRIDAY, April 20 (HealthDay News) -- Two autologous fat grafting procedures, enhanced stromal vascular fraction (SVF) and platelet-rich plasma (PRP) fat grafting, maintain breast volume and three-dimensional contour better than the standard fat grafting procedure, according to a study published online April 13 in Stem Cells Translational Medicine.

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Impaired Fasting Glucose Affects Male Sexual Health

FRIDAY, April 20 (HealthDay News) -- Nearly 20 percent of men with sexual dysfunction have impaired fasting glucose (IFG) and are more likely than men with normal glucose levels to have severe erectile dysfunction (ED), reduced penile blood flow, and overt hypogonadism as well as increased overall cardiovascular (CV) risk, according to a study published online April 10 in The Journal of Sexual Medicine.

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Metformin + Insulin Comparable to Insulin Alone in T2DM

FRIDAY, April 20 (HealthDay News) -- For patients with type 2 diabetes, treatment with metformin and insulin has no significant effect on all-cause or cardiovascular mortality, compared with insulin alone, although data are limited and suffer from bias, according to a meta-analysis published online April 19 in BMJ.

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Letting Go of Regret Linked to Healthy Aging

FRIDAY, April 20 (HealthDay News) -- Emotionally healthy aging is associated with an ability to let go of regrets and not dwell on missed opportunities, according to a study published online April 19 in Science.

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Prisoners at Risk for Non-Communicable Diseases

FRIDAY, April 20 (HealthDay News) -- The prevalence of obesity, inadequate exercise, and poor diet among prisoners may put them at risk for non-communicable diseases (NCDS), according to a review published online April 20 in The Lancet.

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Race, Location Affect Probability of Survival to Age 70

FRIDAY, April 20 (HealthDay News) -- The probability of a person surviving from birth to age 70 varies according to geographic location and gender, with a set of 22 socioeconomic and environmental factors accounting for almost all the variation, according to a study published online April 17 in PLoS One.

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Study Compares Effectiveness of Psoriasis Treatments

FRIDAY, April 20 (HealthDay News) -- The effectiveness of therapies for psoriasis is variable, and may be lower in real-world settings than in trial settings, according to a study published in the April issue of the Archives of Dermatology.

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Eating Low-Fat Dairy Linked to Reduced Stroke Risk

THURSDAY, April 19 (HealthDay News) -- Eating low-fat dairy products is associated with a reduced risk of total stroke and cerebral infarctions, according to a study published online April 19 in Stroke.

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Pulmonary HTN Predicts Heart Failure After Acute MI

THURSDAY, April 19 (HealthDay News) -- Pulmonary hypertension (PH) is a strong independent predictor of heart failure in patients with acute myocardial infarction (AMI), according to a study published in the May 1 issue of The American Journal of Cardiology.

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CDC: HPV-Associated Cancers Strike More Than 30,000 Yearly

THURSDAY, April 19 (HealthDay News) -- Cancers associated with the human papillomavirus (HPV) are diagnosed in nearly 11 out of 100,000 men and women in the United States annually, and HPV vaccines play an important role in reducing the incidence of those cancers for which screening is not approved, according to a report published in the April 20 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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Speed, Ecstasy Use in Teens Predicts Future Depression

THURSDAY, April 19 (HealthDay News) -- Use of meth/amphetamine and ±3,4-methylenedioxymethamphetamine (MDMA) among adolescents is associated with an increased risk of subsequent depressive symptoms, according to study published online April 19 in the Journal of Epidemiology & Community Health.

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Use of PICU Beds for Non-Critical Care Found to Be Significant

THURSDAY, April 19 (HealthDay News) -- Pediatric intensive care unit (PICU) beds are used for critical care services the majority of the time, but even when new patients are waiting for floor beds, at least one PICU bed is usually in use for non-critical care services, according to a study published in the April issue of the Journal of Hospital Medicine.

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Room for Improvement in Knowledge of ABC Levels, Goals

THURSDAY, April 19 (HealthDay News) -- Many individuals with diabetes do not know their last hemoglobin A1C (A1C), blood pressure, and low-density lipoprotein (LDL) cholesterol levels (ABC levels), although the correlation between such knowledge and meeting targets for ABC control is unclear, according to a study published online April 12 in Diabetes Care.

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Review Shows Gum Disease Does Not Cause Heart Disease

THURSDAY, April 19 (HealthDay News) -- Periodontal disease (PD) and atherosclerotic vascular disease (ASVD) share common risk factors, but there is no evidence for a causal relationship between the two, nor evidence that treating PD prevents or alters the outcomes of ASVD, according to a scientific statement from the American Heart Association (AHA) published online April 18 in Circulation.

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Long-Term Air Pollution Linked to Multiple Diseases

THURSDAY, April 19 (HealthDay News) -- Long-term exposure to fine particulate matter in the air increases hospital admissions for respiratory diseases, cardiovascular diseases, stroke, and diabetes in the elderly considerably more than short-term exposure does, according to a study published online April 17 in PLoS One.

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Lower Small-Bowel Obstruction Risk With Laparoscopy

THURSDAY, April 19 (HealthDay News) -- Laparoscopic surgical procedures are associated with a lower incidence of small-bowel obstruction (SBO) compared with open surgery, according to a study published in the April issue of the Archives of Surgery.

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Bariatric Surgery Effective Therapy for Diabetes in Obese

THURSDAY, April 19 (HealthDay News) -- For morbidly obese patients with type 2 diabetes, bariatric surgery is more efficacious than conventional medical treatment, leading to improvement or remission of diabetes and associated comorbidities, according to a study published online April 16 in the Archives of Surgery.

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Hospital Readmission Within 30 Days More Likely in Men

THURSDAY, April 19 (HealthDay News) -- Male gender is associated with increased hospital utilization within 30 days after index discharge, with hospital utilization in the preceding six months a risk factor for both males and females, according to a study published online April 3 in BMJ Open.

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Blood Test IDs Depressive Disorder in Adolescents

THURSDAY, April 19 (HealthDay News) -- A blood test which measures transcriptomic markers may be useful for distinguishing early-onset major depressive disorder (MDD) in adolescents, according to a study published online April 17 in Translational Psychiatry.

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FDA: Clinicians Urged to Stop Using Certain Ultrasound Gel

WEDNESDAY, April 18 (HealthDay News) -- Hospitals, clinics, and health care professionals should immediately discontinue using Other-Sonic Generic Ultrasound Transmission Gel due to risk of bacterial contamination in certain batches, according to a safety communication issued April 18 by the U.S. Food & Drug Administration.

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Albendazole Cuts Enteric Parasite Prevalence in Refugees

WEDNESDAY, April 18 (HealthDay News) -- The administration of a single 600-mg dose of albendazole to United States-bound refugees prior to departure from Africa and Southeast Asia reduces the prevalence of intestinal nematodes, according to a study published in the April 19 issue of the New England Journal of Medicine.

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Chemoradiotherapy Combo Ups Bladder Cancer Control

WEDNESDAY, April 18 (HealthDay News) -- Locoregional control of muscle-invasive bladder cancer is significantly improved with a treatment regimen consisting of radiotherapy and concurrent chemotherapy with mitomycin C and fluorouracil, according to a phase 3 study published in the April 19 issue of the New England Journal of Medicine.

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CV Autonomic Neuropathy Risk for CVD Despite Albumin Status

WEDNESDAY, April 18 (HealthDay News) -- Cardiovascular autonomic neuropathy (CAN) appears to affect the risk of cardiovascular disease even in type 1 diabetes patients with normal albumin excretion rates, according to a study published online April 12 in Diabetes.

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Higher Daily Physical Activity Reduces Alzheimer's Risk

WEDNESDAY, April 18 (HealthDay News) -- Higher total daily physical activity is associated with a reduced risk of developing Alzheimer's disease (AD) and with a lower rate of cognitive decline, according to research published online April 18 in Neurology.

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Basal Cell Carcinoma on Ear Significantly More Aggressive

WEDNESDAY, April 18 (HealthDay News) -- Basal cell carcinoma (BCC) on the ear is significantly more likely to be aggressive, and occurs more frequently in men, according to a study published in the May issue of the Journal of the American Academy of Dermatology.

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Genetic Variants Linked to Brain Size Identified

WEDNESDAY, April 18 (HealthDay News) -- Genetic variants associated with brain size have been identified, including one variant which correlates with hippocampal volume, where size has been associated with Alzheimer's disease and other neurological disorders, according to a study published online April 15 in Nature Genetics.

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Omega-3 Supplements Don't Benefit Patients With MS

WEDNESDAY, April 18 (HealthDay News) -- Omega-3 (ω-3) fatty acid supplements do not improve disease activity in patients with relapsing-remitting multiple sclerosis (MS), according to a study published online April 16 in the Archives of Neurology.

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Study Looks at Patient Perception of Harm During Cancer Care

WEDNESDAY, April 18 (HealthDay News) -- Cancer patients may often experience what they believe to be a preventable, harmful event during the diagnosis or treatment of their cancer, but rarely do they formally report these events, according to research published online April 16 in the Journal of Clinical Oncology.

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Medicare Coverage Gap Leads to Drug Discontinuation

WEDNESDAY, April 18 (HealthDay News) -- Part D Medicare beneficiaries who do not have financial assistance during the coverage gap are at increased risk for cardiovascular drug discontinuation, according to research published online April 17 in Circulation: Cardiovascular Quality and Outcomes.

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Addicted Teens Benefit From 12-Step Meetings Attendance

WEDNESDAY, April 18 (HealthDay News) -- For adolescents with substance use disorder, attendance at 12-step programs is low, although more frequent attendance correlates with greater abstinence, according to a study published online April 16 in Alcoholism: Clinical & Experimental Research.

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New Treatment Offers Benefit for Hypoxic Laryngeal Tumors

WEDNESDAY, April 18 (HealthDay News) -- For patients with squamous cell laryngeal cancer, regional control rates are improved with accelerated radiotherapy (AR) plus carbogen inhalation and nicotinamide (ARCON) treatment compared with AR-alone, with the improvement seen in patients with hypoxic tumors, according to research published online April 16 in the Journal of Clinical Oncology.

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Numerous Genetic Variants Linked to Bone Mineral Density

WEDNESDAY, April 18 (HealthDay News) -- Pooling the results of numerous studies, 56 genetic variants associated with bone mineral density have been identified, of which 14 are associated with fracture risk, according to a study published online April 15 in Nature Genetics.

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For Major Trauma, Survival Up With Helicopter Transport

TUESDAY, April 17 (HealthDay News) -- For patients with major trauma who are admitted to level I or II trauma centers, those who are transported by helicopter have improved survival compared to those transported by ground emergency medical services, according to a study published in the April 18 issue of the Journal of the American Medical Association, a theme issue on comparative effectiveness research.

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ICD-9 Codes Underestimate Statin-Linked Rhabdomyolysis

TUESDAY, April 17 (HealthDay News) -- Use of diagnostic codes, such as International Classification of Diseases -- Ninth Revision (ICD-9) codes, may result in misclassification of rare, adverse drug reactions (ADRs), including the risk of rhabdomyolysis from high-dose simvastatin, according to a research letter published in the April 18 issue of the Journal of the American Medical Association, a theme issue on comparative effectiveness research.

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Fewer Complications With IMRT for Prostate Cancer

TUESDAY, April 17 (HealthDay News) -- For patients with nonmetastatic prostate cancer, treatment with intensity-modulated radiation therapy (IMRT) is associated with fewer complications than proton therapy or conformal radiation therapy, according to a study published in the April 18 issue of the Journal of the American Medical Association, a theme issue on comparative effectiveness research.

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Testosterone Ups Exercise Capacity in Heart Failure

TUESDAY, April 17 (HealthDay News) -- Testosterone supplementation is associated with improved exercise capacity in patients with moderate-to-severe heart failure, according to a meta-analysis published online April 17 in Circulation: Heart Failure.

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Preexposure Chemoprophylaxis Cuts HIV Infection at a Cost

TUESDAY, April 17 (HealthDay News) -- Models show daily oral preexposure chemoprophylaxis (PrEP) in the general population of men who have sex with men (MSM) could prevent a substantial number of HIV infections, but at a high cost, according to a study published in the April 17 issue of the Annals of Internal Medicine.

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Evidence Lacking for Value of CKD Screening and Monitoring

TUESDAY, April 17 (HealthDay News) -- There is no evidence that screening and monitoring for chronic kidney disease (CKD) improves clinical outcomes, according to research published in the April 17 issue of the Annals of Internal Medicine.

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Rate Down But Unintentional Injury Still Top Cause of Death

TUESDAY, April 17 (HealthDay News) -- Although the unintentional injury death rate has declined over the last decade, it is still the leading cause of death among children and adolescents in the United States, according to a study published in the April 16 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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Nutrition, Mobility Predict Early Death in Elderly Cancer Patients

TUESDAY, April 17 (HealthDay News) -- Low nutritional assessment scores, poor mobility, and advanced disease predict early death after chemotherapy initiation among elderly patients with cancer, according to a study published online April 16 in the Journal of Clinical Oncology.

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Depressed Moms May Trigger Infant Night Waking

TUESDAY, April 17 (HealthDay News) -- Maternal depression and dysfunctional cognition impacts mothers' behavior at bedtime and may affect infant sleep, according to a study published online April 17 in Child Development.

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2001 to 2006 Saw Increase in Mohs Surgery for Skin Cancer

TUESDAY, April 17 (HealthDay News) -- For Medicare beneficiaries, the rate of use of Mohs micrographic surgery (MMS) to treat nonmelanoma skin cancer (NMSC) doubled from 2001 through 2006, according to research published in the April issue of the Archives of Dermatology.

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Long-Term Safety Shown for Biodegradable Stent

TUESDAY, April 17 (HealthDay News) -- Long-term follow-up indicates that the fully biodegradable Igaki-Tamai stent is safe for coronary artery use in humans, according to a study published online April 16 in Circulation.

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Low Gastroprotective Drug Adherence Ups Upper GI Events

MONDAY, April 16 (HealthDay News) -- For patients taking cyclooxygenase-2 inhibitors (coxibs), low adherence to gastroprotective agents (GPAs) increases the risk of upper gastrointestinal (UGI) complications, according to a study published online April 16 in Arthritis & Rheumatism.

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Pre-Pregnancy BMI Important Indicator of Offspring Obesity

MONDAY, April 16 (HealthDay News) -- Maternal gestational weight gain (GWG) during the first 20 weeks of pregnancy correlates with body mass index (BMI)-based overweight/obesity and abdominal obesity at age 16, but maternal pre-pregnancy BMI is a stronger indicator of offspring obesity, according to a study published in the May issue of BJOG: An International Journal of Obstetrics and Gynaecology.

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Fast Food Salt Levels Vary Among Six Countries

MONDAY, April 16 (HealthDay News) -- High salt content in pizza, fried chicken, and other products served by multinational food chains varies substantially across six countries, and even incremental reductions of the seasoning could have a big impact on improving the health of the population, according to a study published online April 16 in CMAJ, the journal of the Canadian Medical Association.

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Immunization Pain Reduced Using the Five S's Technique

MONDAY, April 16 (HealthDay News) -- Use of the five S's intervention (swaddling, side/stomach position, shushing, swinging, and sucking) reduces pain scores and crying time following administration of routine immunizations for 2- and 4-month-old infants, according to a study published online April 16 in Pediatrics.

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High SPF Sunscreens Assure Protection From Solar Rays

MONDAY, April 16 (HealthDay News) -- An application of water-resistant sunscreen with a sun protection factor (SPF) of 70 or higher adequately protects people against skin cancer and photodamage even when applied irregularly, according to a study published online April 1 in the Journal of the American Academy of Dermatology.

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Alcohol Use With Opioids Common Even Without Abuse Past

MONDAY, April 16 (HealthDay News) -- Alcohol or sedative use during chronic opioid therapy (COT) for non-cancer pain puts patients at risk for adverse events such as respiratory depression or sedation, and the risk of concurrent use of central nervous system (CNS) depressants is not limited to patients with a history of substance abuse, according to a study published in the March issue of The Journal of Pain.

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IL-32 Expression Upregulated in Chronic Rhinosinusitis

MONDAY, April 16 (HealthDay News) -- Interleukin-32 (IL-32) mRNA expression is significantly higher in biopsies obtained from patients with chronic rhinosinusitis (CRS), compared to levels found in biopsies obtained from individuals without the condition, according to a study published online April 9 in Allergy.

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Liver Insulin Resistance Correlates With Cardiac Risk

MONDAY, April 16 (HealthDay News) -- Liver insulin resistance (IR) may be a significant indicator of cardiovascular disease (CVD) risk among men, and correlates more closely with risk factors than whole-body insulin sensitivity, according to a study published online April 5 in the Journal of Internal Medicine.

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'Choking Game' Linked to Other Risk Behaviors in Young Teens

MONDAY, April 16 (HealthDay News) -- About 6 percent of Oregon male and female eighth-graders participate in the "choking game," an activity in which children apply pressure to the neck to limit oxygen and blood flow in the hopes of experiencing a euphoric feeling once the pressure is released and blood and oxygen rush back to the brain; and participation in this activity is linked to other risk behaviors, according to research published online April 16 in Pediatrics.

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Social Adversity Contributes to Obesity in Girls

MONDAY, April 16 (HealthDay News) -- Preschool-aged girls who experience higher cumulative social adversity at age 1 or age 3 are about twice as likely to exhibit early-onset obesity by age 5 as those without significant risk factors at either time point, according to research published online April 16 in Pediatrics.

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Pegaptanib Reduces Foveal Thickness in Macular Edema

FRIDAY, April 13 (HealthDay News) -- Intravitreally administered injections of the selective vascular endothelial growth factor (VEGF)-165 inhibitor pegaptanib significantly reduces foveal thickness and improves visual acuity in patients with diabetes and macular edema, according to a study published online April 5 in the British Journal of Clinical Pharmacology.

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Metal Binding Important for Metformin Action

FRIDAY, April 13 (HealthDay News) -- The ability of metformin to bind mitochondrial copper may be essential to its mechanism of action, according to a study published online April 9 in Diabetes.

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Calorie Cutting Needed to Meet Youth Obesity Goals

FRIDAY, April 13 (HealthDay News) -- In order for the nation to achieve Healthy People 2020 childhood obesity prevention goals, children on average would need to reduce their daily caloric intake by 64 calories, according to a study published in the May issue of the American Journal of Preventive Medicine.

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Crizotinib Treatment Lowers Total Testosterone Levels

FRIDAY, April 13 (HealthDay News) -- Men with non-small-cell lung cancer (NSCLC) treated with crizotinib exhibit rapid suppression of total testosterone (T) levels compared with those who do not receive crizotinib treatment, according to research published online April 4 in Cancer.

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Herbal Carcinogen Linked to Urothelial Cancer in Taiwan

FRIDAY, April 13 (HealthDay News) -- A carcinogen produced by Aristolochia plants, which are commonly used in herbal remedies in Taiwan, is associated with signature types of DNA damage linked to aristolochic acid in Taiwanese patients with urothelial carcinoma of the upper urinary tract (UUC), according to a study published online April 9 in the Proceedings of the National Academy of Sciences.

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Most Breast Cancer Survivors Experience Lasting Side Effects

FRIDAY, April 13 (HealthDay News) -- The majority of breast cancer survivors experience one or more treatment-related side effects, and the proportion remains stable at six years post-diagnosis, according to a study published in a special supplement to the April 15 issue of Cancer addressing the physical late effects of breast cancer treatment.

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Isomaltulose Doesn't Improve Glycemic Control in Diabetes

FRIDAY, April 13 (HealthDay News) -- For patients with type 2 diabetes, substitution of sucrose with isomaltulose is not associated with improved glycemic control (measured by hemoglobin A1c [HbA1c] levels) at 12 weeks, according to a study published online April 9 in Diabetes Care.

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Obesity Costs Are Higher Than Previous Estimates

FRIDAY, April 13 (HealthDay News) -- Obesity accounts for nearly 21 percent of U.S. health care costs, much higher than previously estimated, according to a study published in the January issue of the Journal of Health Economics.

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TAVI Beneficial in Severe Aortic Stenosis

FRIDAY, April 13 (HealthDay News) -- While all-cause mortality is high in low-flow, low-gradient aortic stenosis patients receiving transcatheter aortic valve implantation (TAVI), surviving patients show significant improvements, according to a study published in the April issue of Catheterization & Cardiovascular Interventions.

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Pain Correlates Most Strongly With Disability in Hispanics With RA

FRIDAY, April 13 (HealthDay News) -- For Hispanic patients with rheumatoid arthritis (RA), self-reported pain correlates most strongly with disability, according to a study published online April 5 in Arthritis Care & Research.

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Sequencing Traditional Chinese Medicines Reveals Surprises

FRIDAY, April 13 (HealthDay News) -- DNA sequencing of traditional Chinese medicines (TCMs) using high-throughput sequencing (HTS) reveals that potentially toxic plant ingredients and traces of endangered animals are present, according to a study published online April 12 in PLoS Genetics.

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Many Women Still Report Drinking During Pregnancy

THURSDAY, April 12 (HealthDay News) -- A considerable proportion of women report continuing to drink during pregnancy, but biomarker tests indicate they are drinking at modest levels, according to a study published online April 6 in Alcoholism: Clinical & Experimental Research.

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Copy Number Variants Tied to Increased Prostate Cancer Risk

THURSDAY, April 12 (HealthDay News) -- Copy number variants (CNVs) of two loci are linked to a significantly higher risk of prostate cancer, according to a study published online April 10 in the Proceedings of the National Academy of Sciences.

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Risk of Sudden Cardiac Death Up for Black Patients With HTN

THURSDAY, April 12 (HealthDay News) -- Black patients with hypertension face a significantly increased risk of sudden cardiac death (SCD) compared with nonblack patients, even after adjusting for multiple confounding variables, according to a study published in the April issue of Heart Rhythm.

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Small Number of Genes Involved in X-Linked Ichthyosis

THURSDAY, April 12 (HealthDay News) -- Patients with X-linked recessive ichthyosis (XLRI) have altered expression in a small number of genes, and although moisturizer treatment improves dryness, it doesn't affect other biophysical properties or gene expression, according to a study published online April 5 in the British Journal of Dermatology.

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Vitamin D3 Levels Not Linked to Academic Achievement

THURSDAY, April 12 (HealthDay News) -- Serum 25-hydroxyvitamin D (25[OH]D)3 concentrations are not associated with academic performance in children, according to a study published online April 9 in the Journal of Epidemiology & Community Health.

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Prolonged Inadequate Sleep Linked to Obesity and Diabetes

THURSDAY, April 12 (HealthDay News) -- Prolonged inadequate sleep at irregular times lowers the resting metabolic rate and leads to defects in pancreatic insulin secretion, increasing the risk for obesity and diabetes, according to a study published in the April 11 issue of Science Translational Medicine.

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Role of Omega-3 in Secondary Prevention of CVD Questioned

THURSDAY, April 12 (HealthDay News) -- For patients with a history of cardiovascular disease (CVD), evidence is lacking for a secondary preventive effect of omega-3 fatty acid supplements, according to a meta-analysis published online April 9 in the Archives of Internal Medicine.

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Majority of Obese Adults Do Try to Lose Weight

THURSDAY, April 12 (HealthDay News) -- Nearly two-thirds of obese adults are trying to lose weight, and those that eat less fat, exercise more, and use prescription weight loss medications are more successful at losing weight, according to a study published online April 10 in the American Journal of Preventive Medicine.

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U.S. Fertility Measures Largely Unchanged Since 2002

THURSDAY, April 12 (HealthDay News) -- Fertility measures for 15- to 44-year olds for 2006 to 2010 are similar to findings from 2002, according to an April 12 data brief issued by the National Center for Health Statistics (NCHS).

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Chronic Depression Patients Pick Acupuncture Over Counseling

THURSDAY, April 12 (HealthDay News) -- Patients with depression can be recruited from primary care to compare acupuncture with counseling and general practitioner (GP) care, according to a study published in the April issue of CNS Neurosciences & Therapeutics.

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Bevacizumab Offers Lasting Improvement in Macular Edema

THURSDAY, April 12 (HealthDay News) -- At two years of follow-up, diabetes-related clinically significant macular edema (CSME) is more effectively improved by intravitreous bevacizumab than with macular laser therapy (MLT), according to a study published online April 9 in the Archives of Ophthalmology.

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Mentholated Cigarettes Linked to Increased Stroke Risk

THURSDAY, April 12 (HealthDay News) -- Mentholated cigarettes are associated with a significantly increased risk of stroke, particularly among women and non-African-American smokers, according to a letter published in the April 9 issue of the Archives of Internal Medicine.

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Pattern of Disc Degeneration Impacts Low Back Pain

WEDNESDAY, April 11 (HealthDay News) -- Contiguous, multilevel disc degeneration (CMDD) is associated with increased likelihood of low back pain (LBP) and pain severity compared with skipped level disc degeneration (SLDD), according to a study published in the April 1 issue of Spine.

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Study Assesses Glucose Monitoring Trends in Tweens

WEDNESDAY, April 11 (HealthDay News) -- During the transition to adolescence, children with type 1 diabetes monitor their blood glucose less frequently, resulting in significant increases in HbA1c levels, according to research published online April 3 in Diabetes Care.

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Antidepressants Don't Worsen Parkinson's Symptoms

WEDNESDAY, April 11 (HealthDay News) -- The antidepressants paroxetine and venlafaxine extended release (XR) reduce depression without worsening motor function in patients with Parkinson's disease, according to a study published online April 11 in Neurology.

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Indomethacin Cuts Incidence of Post-ERCP Pancreatitis

WEDNESDAY, April 11 (HealthDay News) -- For patients who undergo endoscopic retrograde cholangiopancreatography (ERCP), a single dose of rectal indomethacin immediately after the procedure is associated with a significantly reduced incidence of pancreatitis, according to a study published in the April 12 issue of the New England Journal of Medicine.

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Occupational Exposures Put Nurses at Risk of Miscarriage

WEDNESDAY, April 11 (HealthDay News) -- Nurses face an increased risk of spontaneous abortions during early pregnancy from occupational exposure to antineoplastic drugs and sterilizing agents, according to a study published in the April issue of the American Journal of Obstetrics & Gynecology.

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Stroke Risk Much Higher If Sibling Has Had a Stroke

WEDNESDAY, April 11 (HealthDay News) -- Having a sibling who has had a stroke significantly increases the familial stroke risk by at least 60 percent, according to a study published online April 10 in Circulation: Cardiovascular Genetics.

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Mobile Stroke Units Halve Time to Treatment

WEDNESDAY, April 11 (HealthDay News) -- Diagnosis and treatment of stroke in patients at the scene of the emergency rather than at the hospital about halves the time to treatment, according to a study published online April 11 in The Lancet Neurology.

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STI Screening Improves With Free, Home-Based Testing

WEDNESDAY, April 11 (HealthDay News) -- The availability of free and home-based screening tests for sexually transmitted infections (STIs) is associated with a higher rate of screening completion, according to a study published in the April issue of the American Journal of Obstetrics & Gynecology.

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Smoking Found to Be a Risk Factor for Barrett's Esophagus

WEDNESDAY, April 11 (HealthDay News) -- Cigarette smoking may be a modifiable risk factor for Barrett's esophagus, according to a study published in the April issue of Gastroenterology.

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BMD Loss Occurs Early in Androgen Deprivation Therapy

WEDNESDAY, April 11 (HealthDay News) -- The highest average change in bone mineral density (BMD) occurs during early treatment of nonmetastatic, hormone-sensitive prostate cancer in men receiving intermittent androgen deprivation therapy (ADT), according to research published online April 9 in the Journal of Clinical Oncology.

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Perception of Breast Cancer Care Differs From Actual Care Quality

WEDNESDAY, April 11 (HealthDay News) -- The perception of care for women living in inner cities with newly diagnosed, early-stage breast cancer is dependent, in large part, on factors other than the actual quality of care provided, including the quality of the process of getting care, trust in the physician, and perceptions of racism, according to research published online April 9 in the Journal of Clinical Oncology.

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More Gastro Events in Patients With Rheumatoid Arthritis

WEDNESDAY, April 11 (HealthDay News) -- The incidence of upper and lower gastrointestinal (GI) events is higher among patients with rheumatoid arthritis (RA), as is the risk of mortality due to GI events, when compared to individuals without RA, according to a study published online April 1 in the Journal of Rheumatology.

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For Obese, Deep Organs Receive Lower Doses of Radiation

WEDNESDAY, April 11 (HealthDay News) -- For obese individuals, organs deep within the abdomen may receive lower doses of radiation than the organs of normal-weight individuals, with the same scanner operating parameters, according to a study published online April 5 in Physics in Medicine and Biology.

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Injectable Contraceptive Linked to Elevated Breast Cancer Risk

TUESDAY, April 10 (HealthDay News) -- Recent use of the injectable contraceptive depo-medroxyprogesterone acetate (DMPA) for 12 months or longer may approximately double the risk of breast cancer in young women, according to a study published online Feb. 27 in Cancer Research.

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Decision Aid for Chest Pain in ER Engages Patients

TUESDAY, April 10 (HealthDay News) -- Use of a decision aid, a visual patient education tool, helps chest pain patients become more engaged in their care and results in fewer admissions for observation and stress testing, without negatively impacting care outcomes, according to a study published online April 10 in Circulation: Cardiovascular Quality and Outcomes.

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ECG Abnormalities Add to Accuracy of CHD Risk Prediction

TUESDAY, April 10 (HealthDay News) -- Major and minor electrocardiographic (ECG) abnormalities are associated with an increased risk of coronary heart disease (CHD) events, particularly in elderly individuals, according to a study published in the April 11 issue of the Journal of the American Medical Association.

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Increased Risk of Fatal Road Crashes on Tax Day in the U.S.

TUESDAY, April 10 (HealthDay News) -- There is a small, but significant, increase in fatal road crashes on tax day in the United States, according to a letter published in the April 11 issue of the Journal of the American Medical Association.

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Death Risk Similar With High-Dose Losartan, Candesartan

TUESDAY, April 10 (HealthDay News) -- For patients with heart failure, the use of high-dose losartan is not associated with an increased mortality risk compared with high-dose candesartan, according to a study published in the April 11 issue of the Journal of the American Medical Association.

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Strategy of Offering Choice of CRC Screening Ups Adherence

TUESDAY, April 10 (HealthDay News) -- Adherence to colorectal cancer (CRC) screening varies based on the screening strategy, with adherence linked to patient preference and ethnicity/race, according to a study published in the April 9 issue of the Archives of Internal Medicine.

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Frequent, Older Dental X-Rays Linked to Brain Cancer

TUESDAY, April 10 (HealthDay News) -- Frequent bitewing or panorex dental X-rays taken on previous generations of machines are linked to an increased risk of intracranial meningioma, according to a study published online April 10 in Cancer.

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HPV Vaccine Side Effects Not Serious in Young Women

TUESDAY, April 10 (HealthDay News) -- Younger girls are more likely than adult women to report side effects after receiving the quadrivalent human papillomavirus (HPV4; Gardasil) vaccine, but the side effects are non-serious, according to a study published online Jan. 9 in the Journal of Women's Health.

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Mitochondrial Respiratory Capacity, Sperm Motility Linked

TUESDAY, April 10 (HealthDay News) -- Sperm with higher motility have increased mitochondrial respiratory capacity, according to a study published in the April issue of Urology.

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Early Response Is an Indicator for Rectal Cancer Survival

TUESDAY, April 10 (HealthDay News) -- In patients with locally advanced rectal cancer undergoing radical resection, response to neoadjuvant chemoradiotherapy is an early marker that correlates with rates of recurrence-free survival, distant metastases, and local recurrences, according to research published online April 9 in the Journal of Clinical Oncology.

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Alternative Medicine Doesn't Affect Asthma Care in Children

TUESDAY, April 10 (HealthDay News) -- Complementary and alternative medicine (CAM) is not associated with adherence to pediatric asthma treatment, according to a study published online April 9 in Pediatrics.

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Insurers Should Screen Older Smokers for Lung Cancer

TUESDAY, April 10 (HealthDay News) -- Lung cancer screening with low-dose spiral computed tomography could be of substantial value in high-risk smoker populations over the age of 50, and commercial insurers should consider providing coverage for the screening, according to a study published in the April issue of Health Affairs.

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Ocular Tremors Pervasive in Patients With Parkinson's

TUESDAY, April 10 (HealthDay News) -- Ocular tremors, which prevent eye stability while fixating on a target, are pervasive among patients with Parkinson's disease, according to a study published online April 9 in the Archives of Neurology.

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Radiation Exposure High for Patients With GI Disorders

TUESDAY, April 10 (HealthDay News) -- Patients with inflammatory bowel disorders and other organic and functional gastrointestinal (GI) disorders are exposed to high levels of annual and cumulative diagnostic radiation, according to a study published in the March issue of Clinical Gastroenterology and Hepatology.

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High U.S. Cancer Care Costs Seem to Be Worth It

MONDAY, April 9 (HealthDay News) -- For patients with cancer in the United States, the value of additional survival gains have exceeded the additional costs of U.S. health spending compared with European counties, according to a study published in the April issue of Health Affairs.

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Somatic Mutations in Two Genes ID'd in Stomach Cancer

MONDAY, April 9 (HealthDay News) -- Somatic mutations have been identified in two genes, FAT4 and ARID1A, involved in cell adhesion and chromatin remodeling in some patients with stomach cancer, according to a study published online April 8 in Nature Genetics.

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Economic, Health Indices Linked to Elevated Cholesterol

MONDAY, April 9 (HealthDay News) -- For patients with a history of hyperlipidemia, country-level economic and health system indices impact global-level variation in elevated cholesterol, according to a study published online April 9 in Circulation.

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Teen Alcohol Consumption Tied to Benign Breast Disease

MONDAY, April 9 (HealthDay News) -- Adolescent alcohol consumption is associated with increased risk of proliferative benign breast disease (BBD), which is a risk factor for breast cancer, and there is no evidence that adolescent folate intake provides a protective effect against alcohol-associated BBD, according to a study published online April 9 in Pediatrics.

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Variety of Fruits, Vegetables Linked to Lower Diabetes Risk

MONDAY, April 9 (HealthDay News) -- Eating a greater quantity of vegetables and a greater variety of fruits and vegetables (F&V) correlates with a reduced risk of type 2 diabetes (T2D), according to a study published online April 3 in Diabetes Care.

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Evidence Lacking for Sleep Length, Energy Metabolism Link

MONDAY, April 9 (HealthDay News) -- Short sleep duration may affect total daily energy expenditure or directly affect energy metabolism, although more study is required, according to a review published online March 22 in Obesity Reviews.

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Targeted Exercise Relieves Sciatica Pain

MONDAY, April 9 (HealthDay News) -- Active conservative symptom-guided therapy for severe sciatica can safely reduce pain and improve neurological function at a rate that matches or surpasses outcomes from common higher-cost surgical interventions, according to a Danish study published in the April 1 issue of Spine.

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Two Novel Genetic Variants Linked to Childhood Obesity

MONDAY, April 9 (HealthDay News) -- Two new genetic variants have been found to be associated with childhood obesity, according to a study published online April 8 in Nature Genetics.

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Infection May Be Trigger for Venous Thromboembolism

MONDAY, April 9 (HealthDay News) -- Older adults recovering from an infection are at increased risk of being hospitalized for a venous thromboembolism (VTE), according to a study published online April 3 in Circulation.

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Report Highlights Child Deaths From Post-Surgery Codeine Use

MONDAY, April 9 (HealthDay News) -- Researchers have identified three previously unreported instances of severe opioid-induced toxicity in children following adenotonsillectomy for obstructive sleep apnea syndrome, according to a case report published online April 9 in Pediatrics.

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Statins Moderate Effect of Metformin on Prostate Cancer

MONDAY, April 9 (HealthDay News) -- For men with type 2 diabetes treated with metformin, prostate cancer (PCa) incidence varies depending on statin use, with a significantly reduced risk for patients taking a combination of metformin and statins, according to a study published online March 28 in Diabetes Care.

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Lumbar Spinal Stenosis Lowers Health-Related QoL

FRIDAY, April 6 (HealthDay News) -- Patients diagnosed with lumbar spinal stenosis (LSS) have a substantial burden of illness and reduced health-related quality of life (HRQL) compared to the general population, and their HRQL is compounded by associated comorbidities, according to a study published in the March issue of The Spinal Journal.

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Treating Hepatic Encephalopathy Reduces Costs Due to MVAs

FRIDAY, April 6 (HealthDay News) -- For patients with minimal hepatic encephalopathy (MHE), diagnosis and treatment with lactulose reduces costs associated with motor vehicle accidents (MVAs), according to a study published in the April issue of Hepatology.

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Low Blood Adiponectin Predicts Future Asthma Risk in Women

FRIDAY, April 6 (HealthDay News) -- Middle-aged women with low blood adiponectin levels are about twice as likely to develop asthma, particularly if they smoke, according to a study published online April 6 in the American Journal of Respiratory and Critical Care Medicine.

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Wire Grill Brush Bristles Pose Unexpected Danger

FRIDAY, April 6 (HealthDay News) -- For patients presenting with odynophagia or abdominal pain, physicians should consider the possibility of inadvertent wire brush bristle ingestion after eating grilled meat, according to a report published in the April issue of the American Journal of Roentgenology.

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Fetal Pesticide Exposure Affects Birth Weight, Gestation Length

FRIDAY, April 6 (HealthDay News) -- Fetal exposure to organophosphate (OP) insecticides can affect the length of gestation and birth weight, according to a study published online April 5 in Environmental Health Perspectives.

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Cognitive Therapy Has Little Effect on Psychosis Risk

FRIDAY, April 6 (HealthDay News) -- Although cognitive therapy does not reduce the risk of developing psychosis such as schizophrenia for at-risk individuals, it significantly reduces symptom severity for those who do develop psychosis, according to a study published online April 5 in BMJ.

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Early Exposure to Interpersonal Trauma Harms Cognition

FRIDAY, April 6 (HealthDay News) -- Exposure to interpersonal trauma (IPT) in the first years of life is associated with decreased cognitive functioning in childhood, with exposure in the first two years particularly harmful, according to a study published online April 4 in the Journal of Epidemiology & Community Health.

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Endodermal Progenitor Cells Generate Into Multiple Cell Types

FRIDAY, April 6 (HealthDay News) -- Endodermal progenitor (EP) cells derived from embryonic stem cells and induced pluripotent stem cells can differentiate into multiple cell types, including functional pancreatic β-cells, and are not tumorigenic, according to a study published in the April 6 issue of Cell Stem Cell.

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Reduction Noted in Heart Rate Variability During Hot Flashes

FRIDAY, April 6 (HealthDay News) -- Women experiencing hot flashes have a significant reduction in heart rate variability during the hot flash, suggesting a role for the autonomic nervous system, according to a study published in the April issue of Menopause.

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Immunotherapy Tied to Lower Alzheimer's CSF Biomarkers

FRIDAY, April 6 (HealthDay News) -- For patients with mild-to-moderate Alzheimer's disease, immunotherapy treatment with the anti-β-amyloid (Aβ) monoclonal antibody bapineuzumab results in lower concentrations of two cerebrospinal fluid (CSF) biomarkers: total (T)-tau and phosphorylated (P)-tau, according to a study published online April 2 in the Archives of Neurology.

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Antibiotics Safe and Effective to Treat Appendicitis

FRIDAY, April 6 (HealthDay News) -- Although surgery is standard practice for treating appendicitis, uncomplicated acute appendicitis can be safely and effectively treated with antibiotics, according to a meta-analysis published online April 5 in BMJ.

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Toddlers Getting Little Daily Parent-Supervised Outdoor Play

FRIDAY, April 6 (HealthDay News) -- About half of all preschool-aged children do not have even one parent-supervised outdoor playtime per day, according to research published online April 2 in the Archives of Pediatrics & Adolescent Medicine.

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Physical Activity Predicts Functionality in Older Adults

FRIDAY, April 6 (HealthDay News) -- Physically active older adults experience significantly fewer functional limitations than more sedentary older adults, according to a study published online April 5 in the Journal of the American Geriatrics Society.

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Resistant Malaria Increasing on Thailand-Myanmar Border

THURSDAY, April 5 (HealthDay News) -- From 2001 to 2010, an increase was seen in artemisinin resistance in Plasmodium falciparum (P. falciparum) on the Thailand-Myanmar border, which was largely attributable to parasite genetics, according to a longitudinal study published online April 5 in The Lancet.

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Asbestos Exposure Linked to Cardiovascular Death

THURSDAY, April 5 (HealthDay News) -- Occupational exposure to asbestos is associated with a higher risk of dying of cardiovascular disease, according to a study published online April 2 in Occupational & Environmental Medicine.

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Increased Breast Cancer Risk With False-Positive Test

THURSDAY, April 5 (HealthDay News) -- Women with false-positive mammogram tests remain at significantly higher risk of breast cancer for six or more years, compared to women with negative tests, but the size of the excess risk has decreased since the early 2000s, according to a study published online April 5 in the Journal of the National Cancer Institute.

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Low-Energy-Density Diets Effective for Managing Weight

THURSDAY, April 5 (HealthDay News) -- There is an association between energy density and body weight, such that consumption of diets lower in energy density may be an effective strategy for weight management, according to study published online April 5 in the Journal of the Academy of Nutrition and Dietetics.

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Full Weight-Based Chemo Doses Recommended for Obese

THURSDAY, April 5 (HealthDay News) -- The American Society of Clinical Oncology Clinical Practice Guideline on Appropriate Chemotherapy Dosing for Obese Adult Patients With Cancer recommends using full weight-based cytotoxic chemotherapy doses to treat obese patients with cancer, according to an overview published online April 2 in the Journal of Clinical Oncology.

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Studies Investigate Role of De Novo Mutations in Autism

THURSDAY, April 5 (HealthDay News) -- The contribution of de novo mutations to the risk of autism spectrum disorders (ASDs) is complex, according to three sequencing studies published online April 4 in Nature.

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Exercise Training Improves Cardiac Parameters in Lupus

THURSDAY, April 5 (HealthDay News) -- For inactive patients with systemic lupus erythematosus (SLE), a three-month exercise training program is associated with improved chronotropic reserve and heart rate recovery, according to a study published online March 21 in Arthritis Care & Research.

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Flavonoid Intake May Protect Men Against Parkinson's

THURSDAY, April 5 (HealthDay News) -- Total flavonoid intake is significantly associated with a lower risk of Parkinson's disease (PD) in men, particularly the intake of anthocyanins and berries, according to a study published online April 4 in Neurology.

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Esophageal Cancer Surgery Has Lasting Effects on QoL

THURSDAY, April 5 (HealthDay News) -- Long-term survivors of esophageal cancer surgery who experience postoperative complications continue to experience long-lasting adverse effects on their health-related quality of life (HRQL), according to a study published online April 2 in the Journal of Clinical Oncology.

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New Guidelines Issued for Rheumatoid Arthritis Treatment

THURSDAY, April 5 (HealthDay News) -- The 2008 American College of Rheumatology (ACR) guidelines for the treatment of rheumatoid arthritis (RA) have been updated for 2012, according to a special article published in the May issue of Arthritis Care & Research.

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Prenatal Antipsychotics Impact Infant Neuromotor Function

THURSDAY, April 5 (HealthDay News) -- The use of prescribed antipsychotics during pregnancy may result in significantly lower neuromotor performance in 6-month-old infants, according to a study published online April 2 in the Archives of General Psychiatry.

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New Combination Malaria Treatment Equally Effective

THURSDAY, April 5 (HealthDay News) -- Fixed-dose, combination pyronaridine-artesunate treatment is as effective as mefloquine plus artesunate in treating malaria infection, according to a study published in the April 5 issue of the New England Journal of Medicine.

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Medical Malpractice Claims Incur Substantial Defense Costs

WEDNESDAY, April 4 (HealthDay News) -- Defense costs for medical malpractice claims vary among specialties and are higher for claims that result in indemnity payments, according to a letter published in the April 5 issue of the New England Journal of Medicine.

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End-of-Life Decline of Cognitive Functions Are Correlated

WEDNESDAY, April 4 (HealthDay News) -- In the last years of life, cognitive abilities decline rapidly, with a strong correlation between different functions; and cognitive activity is associated with cognitive function and predictive of cognitive decline, according to two studies published online April 4 in Neurology.

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Antibodies to HIV-1 Proteins Impact Vaccine Efficacy

WEDNESDAY, April 4 (HealthDay News) -- Antibodies to HIV-1 proteins may play a role in the efficacy of HIV-1 vaccination, according to a study published in the April 5 issue of the New England Journal of Medicine.

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Cancer Diagnosis Linked to Higher Immediate Suicide Risk

WEDNESDAY, April 4 (HealthDay News) -- A recent cancer diagnosis is associated with a higher risk of suicide and death from cardiovascular causes, with the risk being highest in the weeks after diagnosis, according to a study published in the April 5 issue of the New England Journal of Medicine.

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Diagnostic Coding May Skew Pneumonia Outcomes Data

WEDNESDAY, April 4 (HealthDay News) -- The decline in pneumonia-related hospitalizations and associated inpatient deaths seen in 2003 to 2009 may be a result of diagnostic coding, rather than an actual improvement in outcomes, according to a study published in the April 4 issue of the Journal of the American Medical Association.

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Alcohol, Drug Use Prevalent Among U.S. Adolescents

WEDNESDAY, April 4 (HealthDay News) -- Alcohol and drug use is prevalent among teens, with the median age of alcohol and drug abuse occurring during adolescence, according to a study published in the April issue of the Archives of General Psychiatry.

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Metal-on-Metal Bearing Not Linked to Cancer Incidence

WEDNESDAY, April 4 (HealthDay News) -- Hip replacements with metal-on-metal bearing surfaces do not seem to be associated with cancer incidence, according to study published online April 3 in BMJ.

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Good Long-Term Outcomes for Drug-Eluting Stents

WEDNESDAY, April 4 (HealthDay News) -- Meta-analysis of randomized clinical trials (RCTs) suggests that drug-eluting stents (DESs) significantly reduce repeat revascularizations, with no increase in stent thrombosis (ST), mortality, or recurrent myocardial infarction, but data from observational studies indicate an increased risk of ST with DES use, according to research published in the April 1 issue of The American Journal of Cardiology.

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Reduced-Intensity Chemo Effective in Hodgkin's

WEDNESDAY, April 4 (HealthDay News) -- Treating patients with advanced-stage Hodgkin's lymphoma with a reduced-intensity, six-cycle BEACOPPescalated chemotherapy regimen is more effective and less toxic than eight cycles of the same regimen, according to a study published online April 4 in The Lancet.

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Importance of Diabetes Genetic Variants Unclear

WEDNESDAY, April 4 (HealthDay News) -- Genetic variants associated with type 2 diabetes that affect glucagon-like peptide 1 (GLP-1) are not associated with GLP-1 levels or GLP-1-induced insulin secretion in healthy individuals, according to a study published online March 28 in Diabetes.

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Extensive Neuroanatomic Abnormalities Found in Epilepsy

WEDNESDAY, April 4 (HealthDay News) -- Childhood-onset temporal lobe epilepsy is associated with neuroanatomic abnormalities, although age-related brain changes are largely comparable for those with epilepsy and for controls, according to a study published online April 3 in Epilepsia.

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Childhood Cancer Survivors at Risk for Cardiac Events

WEDNESDAY, April 4 (HealthDay News) -- Childhood cancer survivors (CCSs) treated with anthracyclines and/or cardiac irradiation have a higher risk of developing symptomatic cardiac events (CEs) in the long term, according to a study published online April 2 in the Journal of Clinical Oncology.

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Antibiotic-Resistant S. aureus Found in Many Ambulances

WEDNESDAY, April 4 (HealthDay News) -- Antibiotic-resistant strains of Staphylococcus aureus (S. aureus) are found in the majority of advanced life support (ALS) ambulances in the Chicago area, according to a study published in the April issue of the American Journal of Infection Control.

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Neupro Approved for Advanced Parkinson's and Restless Leg Syndrome

TUESDAY, April 3 (HealthDay News) -- The Neupro (rotigotine) transdermal system has been approved by the U.S. Food and Drug Administration to treat advanced Parkinson's disease and moderate-to-severe restless leg syndrome, the Belgian drug maker UCB said Tuesday in a news release.

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Fluoroquinolone Use Linked to Retinal Detachment

TUESDAY, April 3 (HealthDay News) -- The use of the oral fluoroquinolone antibiotics is associated with an increased risk of retinal detachment, although the absolute risk is small, according to a study published in the April 4 issue of the Journal of the American Medical Association.

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Cetuximab With Chemo Doesn't Improve Colon Cancer Outcome

TUESDAY, April 3 (HealthDay News) -- Adding cetuximab to adjuvant chemotherapy does not improve disease-free survival in stage III colon cancer patients following surgical resection, according to a study published in the April 4 issue of the Journal of the American Medical Association.

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Mammogram Plus MRI or Ultrasound Catches More Cancer

TUESDAY, April 3 (HealthDay News) -- The addition of an ultrasound or magnetic resonance imaging (MRI) to annual mammography results in a higher rate of detection of incident breast cancers, according to a study published in the April 4 issue of the Journal of the American Medical Association.

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Waist Measurements Specify Lipid, BP Levels in Obese Teens

TUESDAY, April 3 (HealthDay News) -- Waist measures (waist circumference and waist-to-height ratio [WHtR]) are associated with lipid and blood pressure levels, with increased WHtR linked to worsened lipid profile and hypertension in obese adolescents, according to a study published online April 2 in the Archives of Pediatrics & Adolescent Medicine.

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Obesity Epidemic in U.S. Worse Than Previously Thought

TUESDAY, April 3 (HealthDay News) -- The body mass index (BMI) substantially underdiagnoses obesity when compared to the dual-energy X-ray absorptiometry (DXA) scan, a direct simultaneous measure of body fat, muscle mass, and bone density, according to a study published online April 2 in PLoS One.

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Cervical Pessary Significantly Reduces Risk of Preterm Birth

TUESDAY, April 3 (HealthDay News) -- For women with a short cervix, use of a cervical pessary significantly reduces the risk of spontaneous delivery before 34 weeks, according to a randomized trial published online April 3 in The Lancet.

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Sleep Apnea, Snorting Linked to Probable Major Depression

TUESDAY, April 3 (HealthDay News) -- Sleep apnea and frequent snorting/stopping breathing during sleep, but not snoring, are associated with probable major depression, according to a study published in the April issue of SLEEP.

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More Than 40 Percent of Patients With RA Are Inactive

TUESDAY, April 3 (HealthDay News) -- More than 40 percent of patients with rheumatoid arthritis are inactive, with lack of motivation and lack of belief in physical activity strongly related to inactivity, according to a study published in the April issue of Arthritis Care & Research.

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Heavy Baby Girls at Future Risk of Cardiometabolic Disease

TUESDAY, April 3 (HealthDay News) -- Heavier baby girls are at increased risk for developing diabetes and cardiovascular disease at age 17 years than are overweight baby boys, according to a study published online March 22 in the Journal of Clinical Endocrinology & Metabolism.

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Inflammatory Regulation Plays Role in Stress, Illness Link

TUESDAY, April 3 (HealthDay News) -- People under chronic stress have glucocorticoid receptor resistance (GCR), which is linked to increased risk of illness, according to research published online April 2 in the Proceedings of the National Academy of Sciences.

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Study Estimates Overdiagnosis From Mammography Screening

TUESDAY, April 3 (HealthDay News) -- Implementation of a mammography screening program leads to a substantial amount of overdiagnosis, according to a study published in the April 3 issue of the Annals of Internal Medicine.

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Most Americans Getting Adequate Amounts of Vitamins, Nutrients

MONDAY, April 2 (HealthDay News) -- Most people in the United States are getting adequate nutrition, but some groups experience lower levels of vital nutrients than that which is recommended for good health, according to the Second National Report on Biochemical Indicators of Diet and Nutrition released April 2 by the U.S. Centers for Disease Control and Prevention.

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Guidelines Improve Outcomes in Nonshockable Cardiac Arrest

MONDAY, April 2 (HealthDay News) -- Implementation of the latest American Heart Association (AHA) resuscitation guidelines, which eliminate "stacked" shocks and emphasize chest compressions, results in significantly improved outcomes for patients experiencing nonshockable out-of-hospital cardiac arrest (OHCA), according to a study published online April 2 in Circulation.

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School Environment Has Little Effect on Teen Mental Health

MONDAY, April 2 (HealthDay News) -- There is limited evidence that the school environment impacts adolescent mental health, according to a review published online April 2 in Pediatrics.

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Serious Eye Disease Linked to Bisphosphonate Use

MONDAY, April 2 (HealthDay News) -- First-time users of oral bisphosphonates have an increased risk of both uveitis and scleritis compared with nonusers, according to a study published online April 2 in CMAJ, the journal of the Canadian Medical Association.

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Utility of Whole-Genome Sequencing Questioned

MONDAY, April 2 (HealthDay News) -- Whole-genome sequencing is unlikely to provide much useful information on an individual's risk of developing common diseases, according to a study published online April 2 in Science Translational Medicine.

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In Taiwan, Diabetes Linked to Increased Parkinson's Risk

MONDAY, April 2 (HealthDay News) -- Individuals with diabetes in Taiwan have a significantly increased risk of Parkinson's disease (PD), which is robust across most age and gender stratifications, according to a study published online March 19 in Diabetes Care.

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Operator Sleep Deprivation Does Not Adversely Affect PCI

MONDAY, April 2 (HealthDay News) -- Percutaneous coronary intervention (PCI) performed in the middle of the night does not impact the same operator's ability to perform PCI the next day, according to a study published online March 30 in Catheterization and Cardiovascular Interventions.

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Six Developmental Trajectories ID'd in Children With Autism

MONDAY, April 2 (HealthDay News) -- Six longitudinal developmental trajectories have been identified among children with autism, with significant heterogeneity seen in developmental pathways within these trajectories, according to a study published online April 2 in Pediatrics.

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Melanoma Incidence Increasing Among Young Adults

MONDAY, April 2 (HealthDay News) -- From 1970 to 2009, there was an increase in the incidence of melanoma among young adults, particularly females, according to a study published in the April issue of the Mayo Clinic Proceedings.

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Malodorous Urine Often Reported for Infants With UTI

MONDAY, April 2 (HealthDay News) -- Parental reports of malodorous urine increase the likelihood of a diagnosis of a urinary tract infection (UTI) in young children being evaluated for a suspected infection, according to a study published online April 2 in Pediatrics.

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Inhibition of Immune Pathway May Trigger Melanoma Growth

MONDAY, April 2 (HealthDay News) -- Melanocyte expression of an immune inhibitory molecule, B7-H1, is associated with the presence of tumor-infiltrating lymphocytes (TILs), according to a study published in the March 28 issue of Science Translational Medicine.

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Maternal Caffeine Intake Doesn't Affect Infant Sleep

MONDAY, April 2 (HealthDay News) -- Heavy caffeine consumption by nursing mothers does not increase the number of nighttime awakenings in 3-month-old infants, according to a study published online April 2 in Pediatrics.

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More Complications After Thyroid Surgery in Elderly

MONDAY, April 2 (HealthDay News) -- Advanced age is a risk factor for complications after thyroidectomy, according to a study published online March 14 in the Journal of Clinical Endocrinology & Metabolism.

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