HELLP Syndrome Associated With Long-Term Risks

HELLP history may complicate subsequent pregnancies with additional comorbid conditions

MONDAY, Oct. 5 (HealthDay News) -- Pregnant women who develop hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome have an increased long-term risk of subsequent pregnancy complications and other comorbidities, according to a study published in the October issue of the American Journal of Obstetrics & Gynecology.

Mounira Habli, M.D., of the University of Cincinnati, and colleagues surveyed 128 patients with a history of HELLP and obtained their medical records. Hemolysis, liver enzyme levels and platelets were assessed according to gestational age of onset (≤28 weeks and >28 weeks).

Among the 128 pregnancies with a history of HELLP, the researchers found that 53 patients achieved another pregnancy, with 24.5 percent developing HELLP syndrome and 28 percent developing preeclampsia. They also observed high rates of new-onset hypertension, depression, and anxiety (33, 32, and 26 percent, respectively). In addition, 2.4 percent of patients required dialysis.

"In conclusion, our findings reveal the presence of significant long-term disorders after HELLP syndrome. These findings are important for patient counseling, close postpartum as well as long-term follow-up," the authors write. "However, patients should be informed that these findings are based on survey results until they are confirmed by large prospective trials."

Abstract
Full Text (subscription or payment may be required)

Related Stories

No stories found.
logo
www.healthday.com