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Cancer Risk Persists in Women Who Undergo CIN Treatment

Risk of cervical cancer elevated 20 years after precancerous lesions are removed

MONDAY, Nov. 21 (HealthDay News) -- Twenty years after undergoing treatment for cervical intraepithelial neoplasia (CIN), women still have an increased risk of cervical cancer, according to a study published in the Nov. 19 edition of the British Medical Journal.

Ilkka Kalliala, a researcher at Helsinki University Central Hospital, Finland, and colleagues studied 7,564 women treated for CIN between 1974 and 2001.

The researchers found 448 new cases of cancer in the women, which was 96 more than they expected to find based on average cancer rates in the female population. The researchers also identified 22 cases of invasive cervical cancer, 10 of which occurred during the second decade after CIN treatment. Previous studies have found no increased cancer risk at eight years following CIN treatment.

Despite these findings, the authors say that CIN treatment is effective. Without such treatment, an estimated 28% to 39% of cases would progress to invasive cancer, the authors write.

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