Some Vaginal Lubricants May Decrease Sperm Motility

Findings may help infertility patients

WEDNESDAY, Oct. 19 (HealthDay News) -- Some vaginal lubricants recommended for infertile couples may cause a decrease in sperm motility or chromatin integrity while other products may not, researchers reported at the annual meeting of the American Society for Reproductive Medicine in Montreal.

Ashok Agarwal, Ph.D., of the Cleveland Clinic Foundation, and colleagues collected sperm samples from 13 normal donors and incubated them at 37 degrees Celsius in human tubal fluid media controls (HTF) or 10% lubricant treatments of Astroglide, FemGlide, Pre-Seed and Replens. In a second study, sperm samples from 12 donors were incubated with the media (positive control), FemGlide, Pre-Seed and KY (negative control) to evaluate chromatin integrity.

The researchers found that Pre-Seed did not hinder sperm motility, while FemGlide-, Replens-, and Astroglide-treated sperm "showed a significant decrease in motility." The authors also found "a decline in sperm chromatin quality" after exposure to FemGlide and KY.

"Pre-Seed does not cause a significant decrease in progressive sperm motility or chromatin integrity, whereas other lubricants used by fertility patients do," the authors write.

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