December 2012 Briefing - OBGYN & Women's Health

Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for December 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Little Change in Global Infertility Rates Since 1990

MONDAY, Dec. 31 (HealthDay News) -- Infertility rates worldwide are similar to those in 1990, though the number of couples affected by infertility rose to nearly 50 million in 2010 due to population growth, according to a study published online Dec. 18 in PLOS Medicine.

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Low Insulin Secretion Tied to Depressive Symptoms in Women

FRIDAY, Dec. 28 (HealthDay News) -- Middle-aged women with insulin secretion levels in the lowest quintile appear to have more than twice the risk of developing new-onset depressive symptoms compared with those with higher insulin secretion levels, according to research published online Dec. 10 in Diabetes Care.

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Dietary PA/OA Fat Ratio May Affect T2DM Risk in Women Only

FRIDAY, Dec. 28 (HealthDay News) -- A diet low in palmitic acid (PA) and high in oleic acid (OA) improves insulin sensitivity and is associated with lower levels of markers of metabolic and oxidative stress in women only, according to a study published online Dec. 13 in Diabetes.

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Surgical Never Events Costly, Cause Considerable Harm

FRIDAY, Dec. 28 (HealthDay News) -- Surgical never events, including retained foreign bodies and wrong-site, wrong-patient, and wrong-procedure surgeries, are costly and incur considerable harm to patients, according to research published online Dec. 18 in Surgery.

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Limited Value for Pap Tests in Endometrial Cancer Recurrence

FRIDAY, Dec. 28 (HealthDay News) -- For women who have undergone a hysterectomy for endometrial cancer, abnormal Papanicolaou (Pap) test results do not aid in diagnosing recurrent disease, according to a study published in the January issue of Obstetrics & Gynecology.

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Teen Vitamin D Intake Not Related to Adult RA or SLE Risk

THURSDAY, Dec. 27 (HealthDay News) -- Dietary vitamin D intake during adolescence does not appear to be associated with the risk of adult-onset rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE), according to research published in the December issue of Arthritis Care & Research.

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Cancer Screening Goals Not Being Met by General Population

THURSDAY, Dec. 27 (HealthDay News) -- In the United States, the general population only meets the recommended cancer screening goals for colorectal cancer, while cancer survivors meet all requirements except for cervical cancer screening, according to a study published online Dec. 27 in Frontiers in Cancer Epidemiology and Prevention.

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Indicators Show Little Change in Overuse of Ambulatory Care

THURSDAY, Dec. 27 (HealthDay News) -- In the United States from 1999 to 2009, the delivery of underused care in the ambulatory setting improved, but fewer changes were seen in inappropriate care, according to a study published online Dec. 24 in the Archives of Internal Medicine.

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Fewer Than a Quarter Call 911 During Acute Heart Problem

THURSDAY, Dec. 27 (HealthDay News) -- During acute coronary syndromes, fewer than one-quarter of patients call 911, according to a study published in the Jan. 1 issue of The American Journal of Cardiology.

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Prophylactic Options Compared for Women With BRCA1/2

THURSDAY, Dec. 27 (HealthDay News) -- The results of a simulation model suggest that, when quality of life is considered, prophylactic bilateral salpingectomy with delayed oophorectomy may be an acceptable alternative to bilateral salpingo-oophorectomy for women with BRCA mutations, according to research published in the January issue of Obstetrics & Gynecology.

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Study Provides More Data for Ovarian Cancer Risk Prediction

THURSDAY, Dec. 27 (HealthDay News) -- Among asymptomatic women, high-risk categories for predicting ovarian cancer risk can be identified using CA125, transvaginal ultrasonography, or both, providing guidance for clinical decisions regarding need for surgery in these women, according to research published in the January issue of Obstetrics & Gynecology.

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Understanding of Infantile Hemangiomas Is Improving

THURSDAY, Dec. 27 (HealthDay News) -- Improved understanding of the pathogenesis of infantile hemangiomas (IHs) is leading to better treatment options, according to a review published online Dec. 24 in Pediatrics.

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Early Menopause Tied to Greater Type 2 Diabetes Risk

THURSDAY, Dec. 27 (HealthDay News) -- Women who experience early menopause have a greater risk of type 2 diabetes, according to a study published online Dec. 10 in Diabetes Care.

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Fertility Drugs Not Linked to Uterine Cancer Recurrence

WEDNESDAY, Dec. 26 (HealthDay News) -- For women who undergo fertility-sparing treatment for uterine cancer, subsequent use of fertility drugs is not associated with a higher incidence of cancer recurrence, according to research published in the January issue of Obstetrics & Gynecology.

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Pre-Consult Genitourinary Exams Performed Infrequently

WEDNESDAY, Dec. 26 (HealthDay News) -- Initial genitourinary (GU) physical examinations are performed in less than a third of cases prior to requesting a urologic consultation, and this rate is affected by patient age and sex, according to research published in the December issue of Urology.

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ACOG: IOM's Gestational Weight Gain Guide Is Basis for Practice

FRIDAY, Dec. 21 (HealthDay News) -- The Institute of Medicine's (IOM) 2009 guidelines on gestational weight gain should serve as a basis for clinical practice, according to a Committee Opinion published by the American College of Obstetricians and Gynecologists (ACOG) in the January issue of Obstetrics & Gynecology.

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Motor Vehicle Incidents Common in Medical Residents

FRIDAY, Dec. 21 (HealthDay News) -- During training, internal medicine residents commonly experience motor vehicle incidents, including crashes and near misses, but less commonly experience blood and body fluid (BBF) exposures, according to research published in the December issue of the Mayo Clinic Proceedings.

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Longitudinal Algorithm May Detect Ovarian Cancer Earlier

FRIDAY, Dec. 21 (HealthDay News) -- Compared with a single-threshold (ST) rule, a parametric empirical Bayes (PEB) longitudinal screening algorithm can identify ovarian cancer earlier and at a lower concentration of CA125, according to research published online Dec. 17 in the Journal of Clinical Oncology.

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Implications of Employer Contraceptive Coverage Explored

WEDNESDAY, Dec. 19 (HealthDay News) -- The Affordable Care Act's (ACA) provision of preventive services, including contraceptive methods, has raised religious objections and complex legal issues for secular employers, according to a perspective piece published online Dec. 19 in the New England Journal of Medicine.

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Childhood Abuse Tied to Adult-Onset Asthma in Black Women

WEDNESDAY, Dec. 19 (HealthDay News) -- There is a positive association between adult-onset asthma and physical abuse in childhood among African-American women, according to a study published online Dec. 7 in the Journal of Allergy and Clinical Immunology.

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Denosumab Does Not Delay Nonvertebral Fracture Healing

WEDNESDAY, Dec. 19 (HealthDay News) -- Denosumab does not appear to delay fracture healing or contribute to other complications when used to treat postmenopausal women with osteoporosis, according to research published in the Dec. 5 issue of The Journal of Bone & Joint Surgery.

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Many Docs Use Social Media to Find, Share Medical Data

WEDNESDAY, Dec. 19 (HealthDay News) -- Most physicians use social media on at least a weekly basis, and report that it improves the quality of patient care they deliver, according to a study published in the September/October issue of the Journal of Medical Internet Research.

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HPV Diagnosis at Older Age May Be 'Latent' Infection Reactivation

TUESDAY, Dec. 18 (HealthDay News) -- Among U.S. women with a sexual debut before the sexual revolution, a lower cumulative probability of human papillomavirus (HPV) infection may be masking an age-related increase in HPV reactivation, according to a study published online Dec. 12 in the Journal of Infectious Diseases.

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Aerobic Exercise Optimal for Reducing Fat Mass, Body Mass

TUESDAY, Dec. 18 (HealthDay News) -- For sedentary, overweight, or obese adults, aerobic training (AT) seems to be the optimal mode of exercise for reducing fat mass and body mass, while a combined approach of AT and resistance training (RT) increases the time commitment with no added loss compared with AT alone, according to a study published in the Dec. 15 issue of the Journal of Applied Physiology.

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Polygenic Risk Score Helpful for Women With Familial Breast CA

TUESDAY, Dec. 18 (HealthDay News) -- For women affected by familial breast cancer, a polygenic risk score based on 22 genomic variants can identify women at high-risk of breast cancer, according to a study published in the Dec. 10 issue of the Journal of Clinical Oncology.

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Recent Increase Noted in Pubic Hair Grooming Injuries

MONDAY, Dec. 17 (HealthDay News) -- Over the last decade there has been a five-fold increase in injuries relating to pubic hair grooming presenting to the emergency department, most of which are due to the use of razors, according to research published in the December issue of Urology.

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Health Care Satisfaction Rated As High by Unacculturated Hispanics

MONDAY, Dec. 17 (HealthDay News) -- Hispanic patients, particularly unacculturated Hispanics, rate their health care experience more highly than do other patient groups, according to a study published in the October issue of the Journal of Immigrant and Minority Health.

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UV Nail Lamps Do Not Significantly Up Skin Cancer Risk

FRIDAY, Dec. 14 (HealthDay News) -- Ultraviolet (UV) nail lamps, used for professional and personal nail techniques, do not pose a clinically significant skin cancer risk, according to a letter to the editor published online Dec. 6 in the Journal of Investigative Dermatology.

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PR+ Cells Add Prognostic Value in Luminal A Breast Cancer

FRIDAY, Dec. 14 (HealthDay News) -- Semiquantitative immunohistochemical expression of progesterone receptor-positive tumor cells improves prediction of survival within luminal A breast cancers, according to a study published online Dec. 10 in the Journal of Clinical Oncology.

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Life Expectancy Up But More Healthy Years Lost to Disability

FRIDAY, Dec. 14 (HealthDay News) -- Although life expectancy is increasing, global estimates of healthy life expectancy indicate that the world's population loses more years of healthy life to disability today than in the past, according to the Global Burden of Disease Study 2010, published in the Dec. 15 special issue of The Lancet.

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Increased Risk of Diabetes for Breast Cancer Survivors

THURSDAY, Dec. 13 (HealthDay News) -- Postmenopausal women with breast cancer have an increased risk of developing diabetes, which varies over time, according to a study published online Dec. 12 in Diabetologia.

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Current Health Costs Pushing Docs to Make Urgent Choices

WEDNESDAY, Dec. 12 (HealthDay News) -- The current growth in health care's share of the gross domestic product (GDP) and need to implement learning health systems is forcing physicians to make important choices, according to a perspective piece published online Dec. 12 in the New England Journal of Medicine.

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ACOG to HHS: Reconsider Age Limit on Plan B Access

WEDNESDAY, Dec. 12 (HealthDay News) -- Physicians from the American Congress of Obstetricians and Gynecologists (ACOG), together with other health organizations, are urging the U.S. Department of Health and Human Services (HHS) to reconsider the age limit for access to Plan B One-Step emergency contraception.

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Any Amount of Smoking Ups Sudden Cardiac Death in Women

WEDNESDAY, Dec. 12 (HealthDay News) -- For women without coronary heart disease (CHD) at baseline, smoking, even in small quantities, is associated with a significantly increased risk of sudden cardiac death (SCD), according to research published online Dec. 11 in Circulation: Arrhythmia and Electrophysiology.

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Higher Carotenoid Levels Tied to Lower Breast Cancer Risk

TUESDAY, Dec. 11 (HealthDay News) -- Higher circulating levels of carotenoids correlate with a reduced risk of breast cancer, according to research published online Dec. 6 in the Journal of the National Cancer Institute.

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Menopause Weight Gain May Up Breast Tumor Growth in Obese

TUESDAY, Dec. 11 (HealthDay News) -- Excess nutrients associated with menopausal weight gain are deposited into the breast tumors of rats who were already obese before menopause, but the tumors can regress after treatment with an insulin sensitizer, according to a study published online Dec. 7 in Cancer Research.

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Maternal BMI Negatively Linked to Child Cognition

MONDAY, Dec. 10 (HealthDay News) -- Maternal pre-pregnancy body mass index (BMI) is negatively associated with children's cognitive performance at ages 5 and 7, although the overall effect size is modest, according to research published online Dec. 10 in Pediatrics.

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Number of Independent Physicians Continues to Decline

MONDAY, Dec. 10 (HealthDay News) -- Physician business models are transforming, with a sustained shift away from independent practice, according to report released by the consulting firm Accenture.

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Primary Care Financially Viable Even With Educational Debt

MONDAY, Dec. 10 (HealthDay News) -- For medical school graduates with median levels of educational debt, a career in primary care is financially viable, according to a study published online Nov. 16 in Academic Medicine.

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Raised Risk of Ischemic Stroke in Women With A-Fib Explored

MONDAY, Dec. 10 (HealthDay News) -- Women with atrial fibrillation (AF) have a higher risk of ischemic stroke than men with AF, related in part to differences in the percent time in the therapeutic range (TTR) associated with warfarin anticoagulation control, according to research published in the Dec. 15 issue of The American Journal of Cardiology.

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Gene-Environment Interaction Ups Risk of Preeclampsia

MONDAY, Dec. 10 (HealthDay News) -- A genetic variant, AGT2R, in mothers, fathers, and neonates is associated with a significantly increased risk of preeclampsia in mothers with a body mass index (BMI) of 25 kg/m² or more, according to a study published online Nov. 5 in Placenta.

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Synergistic Risk of VTE for Women With PCOS Using the Pill

FRIDAY, Dec. 7 (HealthDay News) -- For women with polycystic ovary syndrome (PCOS), the risk of venous thromboembolism is increased for non-users of oral contraceptives, and further increased for users of combined oral contraceptives, according to a study published online Dec. 3 in CMAJ, the journal of the Canadian Medical Association.

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Risk of Asthma Up for Children Born After Fertility Treatment

FRIDAY, Dec. 7 (HealthDay News) -- Children born to subfertile parents are more likely to have asthma, with the likelihood further increased for children born after the use of assisted reproduction technologies (ARTs), according to a study published online Dec. 5 in Human Reproduction.

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Health Care Law Boosts Savings on Meds for Medicare Recipients

FRIDAY, Dec. 7 (HealthDay News) -- Savings on prescription drugs related to the Affordable Care Act have reached $5.1 billion, according to a Dec. 3 news release from the U.S. Department of Health and Human Services.

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Anticompetitive Market Power Common in Managed Care Plans

FRIDAY, Dec. 7 (HealthDay News) -- For each of the three most popular types of managed care plans in the United States (point-of-service plan [POS], health maintenance organization [HMO], and preferred provider organization [PPO]), anticompetitive market power is widespread, according to a Nov. 28 news release from the American Medical Association (AMA).

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Emerging Risk Factors ID'd for Postpartum Depression

THURSDAY, Dec. 6 (HealthDay News) -- Emerging risk factors for postpartum depression include the serotonin transporter (5-HTT) genotype and omega-3 polyunsaturated fatty acid (n-3 PUFA) status, both of which may interact to affect risk, according to a review published in the November issue of The Canadian Journal of Psychiatry.

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Socioeconomic Status Affects Cancer Trial Referrals

THURSDAY, Dec. 6 (HealthDay News) -- Patients of lower socioeconomic status are less likely to be referred to participate in early-phase cancer trials compared with patients of higher socioeconomic status, according to research published online Dec. 3 in the Journal of Clinical Oncology.

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Provider Sites Give Poor Info on Cosmetic Genital Surgery

THURSDAY, Dec. 6 (HealthDay News) -- The Web sites of providers of female genital cosmetic surgery (FGCS) offer a limited amount of poor quality clinical information, according to a study published online Nov. 21 in BMJ Open.

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Evidence Supports Premise: OR Distractions Up Surgical Errors

THURSDAY, Dec. 6 (HealthDay News) -- Typical operating room distractions and interruptions (ORDIs) potentially increase the likelihood of surgical errors among surgical trainees, according to a study published in the November issue of the Archives of Surgery.

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FDA: Public-Private Venture Set to Improve Regulatory Science

THURSDAY, Dec. 6 (HealthDay News) -- The Medical Device Innovation Consortium (MDIC), the first public-private partnership to promote medical device regulatory science, has been established, according to a Dec. 3 news release issued by the U.S. Food and Drug Administration.

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FDA: Zofran 32-mg Dose Pulled From Market

WEDNESDAY, Dec. 5 (HealthDay News) -- The 32-mg, single intravenous dose of Zofran (ondansetron), an anti-nausea drug, is being removed from the market due to its potential to cause serious, even fatal, cardiac damage, according to a Drug Safety Communication (DSC) issued Dec. 4 by the U.S. Food and Drug Administration.

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Microarray Analysis May Add to Karyotyping for Prenatal Testing

WEDNESDAY, Dec. 5 (HealthDay News) -- Microarray analysis can be a useful addition to karyotyping in prenatal testing and appears to be helpful in the investigation of stillbirth, according to two studies published in the Dec. 6 issue of the New England Journal of Medicine.

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Strict Ovarian CA Screening Adherence Called for in High-Risk

WEDNESDAY, Dec. 5 (HealthDay News) -- For women at higher risk for ovarian and/or fallopian tube cancer (OC/FTC), annual screening offers high sensitivity for detection of incident cancers, but few of these cancers are stage I or II, according to research published online Dec. 3 in the Journal of Clinical Oncology.

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Extended Sleep Time Linked to Reduced Pain Sensitivity

WEDNESDAY, Dec. 5 (HealthDay News) -- Extending bedtime for sleepy healthy adults reduces daytime sleepiness and correlates with reduced pain sensitivity, according to a study published in the Dec. 1 issue of SLEEP.

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From 1995 to 2006, Survival Up for Extremely Preterm Babies

WEDNESDAY, Dec. 5 (HealthDay News) -- For babies born extremely preterm, survival increased from 1995 to 2006, but the number of serious health problems remained largely unchanged, according to two studies published online Dec. 4 in BMJ.

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Resistance Exercise Offers More Prolonged Glycemic Control

WEDNESDAY, Dec. 5 (HealthDay News) -- For patients with type 1 diabetes, resistance exercise is associated with a smaller initial decline in blood glucose compared with aerobic exercise, but offers a more prolonged reduction in post-exercise glycemia, according to research published online Nov. 19 in Diabetes Care.

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Five-Hour Protected Sleep Feasible for Medical Interns

TUESDAY, Dec. 4 (HealthDay News) -- Implementation of a five-hour period of protected sleep is feasible for medical interns on long shifts, resulting in interns getting more uninterrupted sleep and feeling more alert the next day, according to a study published in the Dec. 5 issue of the Journal of the American Medical Association.

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Smoking, Depression Tied to Lower Bone Accrual in Teen Girls

TUESDAY, Dec. 4 (HealthDay News) -- Depression and smoking appear to have a negative impact on bone accrual in adolescent girls, according to a study published online Dec. 4 in the Journal of Adolescent Health.

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ART Cuts HIV Infection in Serodiscordant Couples in China

MONDAY, Dec. 3 (HealthDay News) -- For uninfected partners of HIV-positive individuals in China, transmission is reduced with antiretroviral therapy for the HIV-positive individual, according to a study published online Dec. 1 in The Lancet.

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Fetal NSAID Exposure Not Tied to Persistent Pulmonary HTN

MONDAY, Dec. 3 (HealthDay News) -- There appears to be no association between persistent pulmonary hypertension of the newborn (PPHN) and gestational exposure to nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, according to a study published online Dec. 3 in Pediatrics.

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Improved Survival Seen in Ovarian CA With Metformin Use

MONDAY, Dec. 3 (HealthDay News) -- For women with ovarian cancer, metformin use is associated with significantly improved survival, according to a study published online Dec. 3 in Cancer.

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Increasing Number of Workers in Self-Insured Health Plans

MONDAY, Dec. 3 (HealthDay News) -- There has been a recent increase in the percentage of workers in the private sector who are enrolled in self-insured health plans, in which the employer assumes the financial risk related to health insurance (unlike a fully-insured plan, where the insurance company assumes the risk), according to research published in the November issue of the Employee Benefit Research Institute's Notes.

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Epidural Steroid Shot Has Adverse Effect on Bone Density

MONDAY, Dec. 3 (HealthDay News) -- For postmenopausal women, treatment of the pain associated with radiculopathy with epidural steroid injection (ESI) has an adverse effect on bone mineral density (BMD), according to a study published in the Dec. 1 issue of Spine.

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