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May 2010 Briefing - OBGYN & Women's Health

Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for May 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

HER2 Screening on Core Needle Biopsies Found Reliable

FRIDAY, May 28 (HealthDay News) -- Screening breast core needle biopsies (CNB) for human epidermal growth factor receptor 2 (HER2) using immunohistochemistry (IHC) is reliable when applying new American Society of Clinical Oncology-College of American Pathologists (ASCO-CAP) testing criteria, according to research published online May 24 in the Journal of Clinical Oncology.

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Genetic Tests That Don't Ease Decision Making Not Desired

FRIDAY, May 28 (HealthDay News) -- Genetic information that does not clarify decision making about cancer treatment may not be desired, and its impact differs depending on clinical relevance to the recipient, according to research published online May 24 in the Journal of Clinical Oncology.

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Review Examines Racial, Ethnic Reproductive Health Disparities

THURSDAY, May 27 (HealthDay News) -- Racial and ethnic disparities of uncertain etiology exist in several areas of reproductive health, suggesting a need for further research to understand the source of the disparities and to optimize care, according to a review published in the May issue of the American Journal of Obstetrics & Gynecology.

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Antiretroviral Therapy Greatly Cuts HIV Partner Transmission

THURSDAY, May 27 (HealthDay News) -- In heterosexual HIV-1 patients, antiretroviral therapy (ART) can reduce the risk of HIV transmission to sexual partners by 92 percent, according to research published online May 27 in The Lancet.

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Breast Imaging Techniques May Enhance Cancer Detection

WEDNESDAY, May 26 (HealthDay News) -- Contrast-enhanced breast magnetic resonance imaging can detect malignancy in probably benign lesions in the accepted range for mammographically detected Breast Imaging and Reporting and Data System (BI-RADS) category 3 lesions, and mammographic digital screening offers the potential to increase the rate of invasive cancers detected on the basis of calcifications, according to two studies published in the June issue of Radiology.

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Large Variations in C-Section Rates Seen in British Columbia

TUESDAY, May 25 (HealthDay News) -- There is a large, unexplained variation in rates of cesarean deliveries across the 16 health service delivery districts of British Columbia, Canada, according to research published in the June issue of Obstetrics & Gynecology.

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Predisposition to Spontaneous Preterm Delivery Inherited

TUESDAY, May 25 (HealthDay News) -- Spontaneous preterm birth is more likely to occur in women who were born spontaneously preterm themselves, or who have siblings who were, according to research published in the June issue of Obstetrics & Gynecology.

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Pregnant Women Using Herbals Despite Lack of Safety Data

TUESDAY, May 25 (HealthDay News) -- Many women use herbal or natural products immediately prior to or during pregnancy, though little is known about these products' safety or efficacy, according to two articles published in the May issue of the American Journal of Obstetrics & Gynecology.

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Increasing Exercise Linked to Decreasing Obesity in Women

TUESDAY, May 25 (HealthDay News) -- In adult women, there is a crude, graded inverse dose-response relationship between total volume of leisure-time physical activity and obesity, according to a study published in the May issue of the Journal of Epidemiology and Community Health.

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H1N1 in Pregnant Women Is Serious Threat to Fetuses

TUESDAY, May 25 (HealthDay News) -- Pregnant women admitted to the hospital with pandemic novel influenza A(H1N1) are at increased risk for abdominal and gastrointestinal symptoms, fetal distress and mortality, emergency cesarean delivery, and premature births, according to research published in the May 24 issue of the Archives of Internal Medicine.

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Alfalfa Sprouts Recalled Due to Salmonella Outbreak

MONDAY, May 24 (HealthDay News) -- Caldwell Fresh Foods has issued a recall of raw alfalfa sprouts due to a Salmonella Newport outbreak in 10 states, according to the U.S. Food and Drug Administration.

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Misoprostol Does Not Decrease Postpartum Hemorrhage

FRIDAY, May 21 (HealthDay News) -- The prostaglandin analogue misoprostol, when added to standard uterotonic therapy, does not result in decreased postpartum blood loss, according to research published in the May 22 issue of The Lancet.

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Metformin Associated With Decreased B-12

FRIDAY, May 21 (HealthDay News) -- Patients being treated with metformin to control their diabetes may have a higher risk of decreased levels of vitamin B-12 and increased homocysteine levels, according to research published in the May 20 online edition of the BMJ.

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Cesarean Delivery and Celiac Disease Significantly Associated

THURSDAY, May 20 (HealthDay News) -- There is a significant association between cesarean delivery and celiac disease but not Crohn's disease or ulcerative colitis, according to research published online May 17 in Pediatrics.

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Faster Weight Loss Appears to Yield Better Results

THURSDAY, May 20 (HealthDay News) -- People who lose greater amounts of weight initially in weight-loss attempts may experience better weight loss and maintenance results than those who lose weight gradually, according to research published in the June issue of the International Journal of Behavioral Medicine.

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Vitamin D Insufficiency Common in Young Women

THURSDAY, May 20 (HealthDay News) -- Many U.S. women of childbearing age have vitamin D insufficiency, and the current recommended dosage for prenatal vitamin D supplementation may need to be increased to reach recommended levels, according to a study in the American Journal of Obstetrics & Gynecology.

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Fathers Show Risk of Prenatal, Postpartum Depression

TUESDAY, May 18 (HealthDay News) -- A substantial number of expecting and new fathers have prenatal and postpartum depression, and paternal depression is moderately correlated with maternal depression, according to research published in the May 19 issue of the Journal of the American Medical Association.

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Mammograms Before Age 40 May Not Be Appropriate

FRIDAY, May 14 (HealthDay News) -- Screening mammography for women under age 40 results in high rates of recall and additional imaging but low cancer detection rates, according to research published online May 3 in the Journal of the National Cancer Institute.

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Steps Per Day Linked to Metabolic Syndrome Prevalence

THURSDAY, May 13 (HealthDay News) -- Although public health recommendations have tended to focus on moderate-to-vigorous physical activity, an active lifestyle as measured by steps per day is associated with a reduced prevalence of both metabolic syndrome (MetS) and its cardiovascular disease (CVD) risk factors, according to research published online May 4 in the American Journal of Preventive Medicine.

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Environmental Exposures Can Affect Puberty in Young Girls

THURSDAY, May 13 (HealthDay News) -- Environmental exposure to the chemical classes known as phenols, phthalates and phytoestrogens may affect young girls' pubertal development, putting them at risk for health complications later in life, according to a study published online in Environmental Health Perspectives.

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Maternal Vitamin A Improves Offspring's Lung Function

WEDNESDAY, May 12 (HealthDay News) -- Maternal vitamin A supplementation before, during, and after pregnancy in an undernourished population appears to result in improved lung function in offspring, according to a study reported in the May 13 issue of the New England Journal of Medicine.

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Removing Financial Incentives May Reduce Performance

WEDNESDAY, May 12 (HealthDay News) -- The focus of clinicians may change and their performance levels could drop when previously established financial incentives are removed, according to research published May 11 in BMJ.

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New FDA Program Targets Misleading Drug Advertising

WEDNESDAY, May 12 (HealthDay News) -- The U.S. Food and Drug Administration has announced the launch of a new program to educate health care providers regarding their role in making certain that advertisements and promotions for prescription drugs are truthful and not misleading.

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Micrometastases Mean Worse Prognosis in Breast Cancer

WEDNESDAY, May 12 (HealthDay News) -- Breast cancer patients with micrometastases in their lymph nodes have a worse prognosis than node-negative patients, and may be more similar in prognosis to patients with macrometastases, according to research published online May 10 in the Journal of Clinical Oncology.

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High-Dose Vitamin D Linked to Falls, Fractures in Women

TUESDAY, May 11 (HealthDay News) -- Older women receiving an annual large dose of vitamin D may have an increased risk of falls and fractures, according to research published in the May 12 issue of the Journal of the American Medical Association.

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CDC: U.S. Preterm Birth Rate Declines From 2006 to 2008

TUESDAY, May 11 (HealthDay News) -- In 2008, for the second year in a row, the U.S. preterm birth rate (defined as birth prior to 37 weeks of gestation) declined after a long period of relatively steady increase, according to a new report from the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Radiation for Wilms Tumor May Affect Future Pregnancies

TUESDAY, May 11 (HealthDay News) -- Women who have had prior radiation treatment for unilateral Wilms tumor diagnosed in childhood have a higher risk of pregnancy and birth complications, according to research published online May 10 in the Journal of Clinical Oncology.

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Primary Ovarian Insufficiency Patients Often Still Have Eggs

MONDAY, May 10 (HealthDay News) -- The majority of young women with primary ovarian insufficiency (POI) still have immature eggs in their ovaries, suggesting that treatment to restore fertility might be possible, according to research published in Fertility and Sterility.

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High-Pressure Jobs Tied to Heart Disease Risk in Women

FRIDAY, May 7 (HealthDay News) -- Women in a high-pressure work environment have an increased risk of developing ischemic heart disease, according to research published in the May issue of Occupational and Environmental Medicine.

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Hormonal Contraceptives Tied to Female Sexual Dysfunction

FRIDAY, May 7 (HealthDay News) -- Risk for female sexual dysfunction (FSD) is higher among women taking hormonal contraceptives, according to research published online May 4 in the Journal of Sexual Medicine.

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Estrogen Use Linked to More Mammograms, Biopsies

FRIDAY, May 7 (HealthDay News) -- Postmenopausal women taking estrogen alone are more likely to have otherwise avoidable mammograms with short-interval follow-up recommendations or breast biopsies, and their biopsies may be less commonly diagnosed as cancer; however, breast cancer detection among these women is not significantly compromised except, perhaps, in the early years of use, according to research published online May 3 in the Journal of Clinical Oncology.

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New Hormonal Contraceptive Approved

THURSDAY, May 6 (HealthDay News) -- The Bayer Healthcare Pharmaceuticals combination hormonal contraceptive Natazia has been approved by the U.S. Food and Drug Administration.

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Drinking During Pregnancy May Raise Child's Leukemia Risk

THURSDAY, May 6 (HealthDay News) -- In utero exposure to alcohol is associated with a significantly increased risk of childhood acute myeloid leukemia (AML), which is relatively rare, according to research published in the May issue of Cancer Epidemiology, Biomarkers & Prevention.

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Preconception Counseling Benefits Teens With Diabetes

THURSDAY, May 6 (HealthDay News) -- A preconception counseling program aimed at female teenagers with type 1 diabetes is beneficial and cost-effective, and its effects are sustained for at least nine months, according to research published in the April issue of Diabetes Care.

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White Paper Addresses Pros and Cons of HPV Typing

WEDNESDAY, May 5 (HealthDay News) -- A new white paper -- "What is the Role of HPV Typing in the United States Now and in the Next Five Years in a Vaccinated Population?" -- provides guidance to clinicians about the administration of advanced screening technologies for cervical cancer prevention. The paper was published online April 24 in Gynecologic Oncology.

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Global Endometrial Ablation Helpful for Bleeding Disorders

WEDNESDAY, May 5 (HealthDay News) -- Women with bleeding disorders who undergo global endometrial ablation (GEA) for menorrhagia report improved health-related quality of life (HRQoL) and high satisfaction after the procedure, according to research published in the April issue of the American Journal of Obstetrics & Gynecology.

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Vitamin A May Not Prevent Pregnancy-Related Deaths

TUESDAY, May 4 (HealthDay News) -- Weekly vitamin A supplements given to women of reproductive age may not reduce pregnancy-related deaths or all-cause mortality, according to research published online May 4 in The Lancet.

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Antidepressants in Pregnancy May Impact Child Behavior

MONDAY, May 3 (HealthDay News) -- Antidepressant use during pregnancy and twin birth weight differences may affect later behavior in children, while nicotine use during pregnancy may lead to sleep disturbances in children, according to three studies published in the May issue of the Archives of Pediatrics & Adolescent Medicine.

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