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Earlier Embryo Transfer Improves Pregnancy Rates

Women who respond poorly to ovarian hyperstimulation benefit

TUESDAY, July 25 (HealthDay News) -- Women who respond poorly to ovarian hyperstimulation have higher pregnancy rates when embryos are transferred at day 2 rather than day 3 following oocyte retrieval, according to an article in the July issue of Fertility and Sterility.

Mustafa Bahceci, M.D., and colleagues from Bahceci Women Health Care Center and German Hospital in Istanbul, Turkey, randomized 281 women who had a poor ovarian response to controlled ovarian hyperstimulation to receive an embryo transfer at either day 2 or day 3 after oocyte retrieval.

The researchers found that women receiving an embryo transfer at day 2 had significantly higher pregnancy rates per oocyte retrieval and per embryo transfer, with rates of 37.2 percent and 38.9 percent, respectively. However, implantation rates did not differ significantly between the two groups, according to the study.

"Our results demonstrated that transferring embryos on day 2 could provide an alternative to the management of poor responder patients," Bahceci and colleagues conclude.

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