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Imaging Technique Identifies Uterine Abnormalities

Technique useful in infertile women and women with abnormal uterine bleeding

FRIDAY, Dec. 29 (HealthDay News) -- Saline infusion sonohysterography, or SIS, an imaging technique involving the instillation of sterile saline into the endometrial lumen during transvaginal sonography to enhance endometrial visualization, is effective at identifying uterine abnormalities in infertile women and women with abnormal uterine bleeding, researchers report in the December issue of Fertility and Sterility.

Ilan Tur-Kaspa, M.D., from the Institute for Human Reproduction in Chicago, and colleagues used SIS to compare uterine anomalies and malformations in 600 women referred for infertility work-up and 409 women with abnormal uterine bleeding.

The researchers found that more women with abnormal uterine bleeding had intracavitary abnormalities (39.6 versus 16.2 percent) including polyps, submucous fibroids and adhesions. In contrast, more women referred for infertility had uterine anomalies (20 versus 9.5 percent), with arcuate uterus being the most common finding.

"An SIS procedure for infertility work-up revealed a substantial percentage of infertile patients with intracavitary abnormalities and uterine anomalies," the authors conclude. "Because the technique is safe, well-tolerated and feasible in an outpatient setting, SIS should be considered routinely in the early stage of infertility and abnormal uterine bleeding investigation."

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