August 2006 Briefing - Ophthalmology

Here are what the editors at HealthDay consider to be the most important developments in Ophthalmology for August 2006. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Gene Variants Associated with Macular Degeneration

MONDAY, Aug. 28 (HealthDay News) -- Researchers have identified variants of the complement factor H (CFH) gene that influence the risk of developing age-related macular degeneration but do not affect the protein sequence, according to two studies published online Aug. 27 in Nature Genetics.

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Gene Variant Increases Retinopathy Risk in Diabetics

WEDNESDAY, Aug. 23 (HealthDay News) -- Patients with diabetes or impaired glucose tolerance have nearly twice the risk of developing retinopathy if they carry a variant of the insulin-like growth factor-1 (IGF-1) gene, according to a study in the August issue of Diabetes.

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At-Home Contamination May Be Cause of Fusarium Keratitis

TUESDAY, Aug. 22 (HealthDay News) -- The outbreak of the corneal infection Fusarium keratitis linked to the ReNu with MoistureLoc brand of contact lens solution was most likely due to contamination outside the manufacturing or storage processes, possibly in the patients' homes, according to a study in the Aug. 23/30 issue of the Journal of the American Medical Association. However, it is unlikely that poor contact lens hygiene practices were the major cause of the outbreak.

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Macrophages in Eye May Inhibit Macular Degeneration

MONDAY, Aug. 21 (HealthDay News) -- Macrophages may play an important role in suppressing neovascularization in the eye and interleukin 10 (IL-10), which inhibits macrophage activity, could be an important therapeutic target for age-related macular degeneration, according to a study in mice published in the August issue of PLOS Medicine.

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Carotenoids May Cut Macular Degeneration Risk in Women

FRIDAY, Aug. 18 (HealthDay News) -- High intake of two carotenoids -- lutein and zeaxanthin -- found in foods such as leafy green vegetables, corn and egg yolks, reduce the risk of developing age-related macular degeneration, or AMD, in women under 75 years of age, according to a report in the August issue of the Archives of Ophthalmology.

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Retinal Cells Produced from Human Embryonic Stem Cells

FRIDAY, Aug. 18 (HealthDay News) -- Scientists have developed a method to produce retinal cells from human embryonic stem cells, which may help treat diseases associated with retinal degeneration, according to a study published online Aug. 14 in the Proceedings of the National Academy of Sciences.

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SAFE Strategy Effective in Trachoma-Endemic Areas

MONDAY, Aug. 14 (HealthDay News) -- The combination of surgery, antibiotics, facial cleanliness and environmental change, collectively known as SAFE, is effective in tackling trachoma in areas where it is endemic, according to a study in the Aug. 12 issue of The Lancet.

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Woman Damages Vision After Prednisolone Self-Treatment

FRIDAY, Aug. 11 (HealthDay News) -- A 64-year-old woman who self-diagnosed myalgic encephalomyelitis permanently damaged her eyesight as a result of four years of therapy with oral prednisolone, purchased from an online pharmacy based in Thailand, according to a report published in the Aug. 12 issue of The Lancet.

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Magnetic Brain Stimulation Enhances Peripheral Vision

TUESDAY, Aug. 8 (HealthDay News) -- Researchers have shown that magnetic stimulation of the brain in the visual cortex can stimulate activity in other remote but connected regions of the visual cortex and possibly enhance peripheral vision, according to a report in the Aug. 8 issue of Current Biology.

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Physician's Briefing