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Intermediate Uveitis in Children May Be Self-Limiting

Study finds limited visual loss in subjects despite high rate of ocular complications

MONDAY, April 17 (HealthDay News) -- In children, intermediate uveitis might resolve after several years, according to a study published in the April issue of the American Journal of Ophthalmology.

Joke de Boer, M.D., of University Medical Center Utrecht in the Netherlands, and colleagues examined 32 patients with intermediate uveitis who had an onset of ocular disease before age 16.

The researchers observed bilateral involvement in 94 percent of the patients. They also observed remission in seven out of 15 patients (47 percent) with completed follow-up of five years. For all 32 patients, they found a mean time to remission of 6.4 years. The most frequent complication -- optic disk edema -- was observed in 71 percent of patients, and the most common cause of visual loss -- cystoid macular edema -- was observed in 44 percent.

"Visual loss was limited despite the high rate of severe ocular complications," the authors conclude. "Visual outcome was favorable as only three patients developed unilateral acuity of less than 0.1 after five-year follow-up, and no additional blind eyes manifested."

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