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Eye Test Has High Sensitivity for Detecting Glaucoma

But abnormal frequency-doubling threshold perimetry results may have no detectable cause

FRIDAY, Oct. 12 (HealthDay News) -- Frequency-doubling threshold perimetry has a high sensitivity for detecting glaucoma but the cause of abnormal results may be difficult to identify, according to a report published in the October issue of the Archives of Ophthalmology.

Ya Xing Wang, M.D., of the Beijing Institute of Ophthalmology in China, and colleagues performed ophthalmic examinations with fundus photography and frequency-doubling threshold perimetry in 4,349 subjects aged 40 and older.

Among the 207 glaucomatous eyes, the researchers found that 74 (35.7 percent) showed no abnormalities on frequency-doubling threshold perimetry, which suggested a diagnostic sensitivity of 64.3 percent. They also found that abnormal frequency-doubling threshold perimetry results were associated with a probability of about 15 percent for glaucoma. Among the 905 eyes with a visual field defect, the researchers could not identify the cause in 450 eyes (49.7 percent).

"For 85 percent of the subjects with abnormal results of frequency-doubling threshold perimetry, other reasons for visual field defects were present, such as diabetic retinopathy, retinal vein occlusions, age-related macular degeneration and cataract, or a cause of the visual field defect could not be found," the authors write.

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