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Increased Risk of Death Persists After Hip Fracture

Excess annual mortality observed in all patients, but is higher in men at any given age

THURSDAY, March 18 (HealthDay News) -- In older adults, hip fracture is associated with both a short- and long-term increased risk of death, according to a meta-analysis published in the March 16 issue of the Annals of Internal Medicine.

Patrick Haentjens, M.D., of the Universitair Ziekenhuis Brussel in Belgium, and colleagues conducted a meta-analysis of prospective cohort studies that assessed mortality in women (22 cohorts) and men (17 cohorts) ages 50 years and older with hip fracture.

In the first three months after hip fracture, the researchers found that the risk for all-cause mortality was increased by 5.75-fold in women and 7.95-fold in men. They also found that excess annual mortality persists over time for both women and men. Compared to Caucasian women age 80 without a hip fracture, they estimated that Caucasian women with a hip fracture at age 80 have excess annual mortality of 8, 11, 18, and 22 percent at one, two, five, and 10 years, respectively, after the fracture. They also estimated that men with a hip fracture at age 80 have excess annual mortality of 18, 22, 26, and 20 percent at one, two, five and 10 years, respectively, after the fracture.

"At any given age, excess mortality after hip fracture is higher in men than in women," the authors conclude. "These findings may be helpful when performing cost-effectiveness analyses of hip fracture prevention strategies or designing treatment strategies in patients with hip fracture."

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